penicillamine and hydralazine

penicillamine has been researched along with hydralazine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199019 (61.29)18.7374
1990's7 (22.58)18.2507
2000's3 (9.68)29.6817
2010's2 (6.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Gladkikh, SP; Piruzian, LA; Podymov, VK2
CHase, PH; Lee, SL1
Asboe-Hansen, G4
Rumsby, PC; Shepherd, DM1
Schwarz, JA1
Chaudhuri, G; Cuevas, JM; Ignarro, LJ; Vargas, HM1
Sim, E2
Gatenby, PA1
Biarese, V; Cargnino, M; Lerda, R; Lovisetto, P; Mairano, D; Marchi, L1
Bernstein, RM; Clayton, AL; Hobbs, RN1
Batchelor, JR; Spears, CJ1
Messner, RP; Thomas, TJ1
Barland, P; Epstein, A1
Harpey, JP1
Berning, H; Muehrcke, RC; Thiele, KG1
Holborow, EJ1
Gharavi, A; Hughes, GR; Mansilla, R; Ryan, PF; Rynes, RI; Sewell, J1
Ha, V; Marshall, MK; Pinnell, SR; Walker, LC; Yeowell, HN1
Bennett, T; Gardiner, SM; Kemp, PA; Moncada, S; Palmer, RM1
Nässberger, L1
Chambers, TJ; Chow, JW; Fox, SW; Lean, JM1
Choi, HK; Merkel, PA; Niles, JL; Walker, AM1
Li, J; Mannargudi, B; Uetrecht, JP1

Reviews

8 review(s) available for penicillamine and hydralazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug-induced systemic lupus erythematosus: a critical review.
    Seminars in arthritis and rheumatism, 1975, Volume: 5, Issue:1

    Topics: Adult; Allopurinol; Anti-Arrhythmia Agents; Anticonvulsants; Antithyroid Agents; Antitubercular Agents; Contraceptives, Oral, Synthetic; Female; Humans; Hydralazine; Hypertension; Lupus Erythematosus, Systemic; Male; Middle Aged; Penicillamine; Procainamide; Psychotropic Drugs; Reserpine; Sulfonamides; Tuberculosis

1975
Drug-induced immune complex disease.
    Biochemical Society transactions, 1991, Volume: 19, Issue:1

    Topics: Amino Acid Sequence; Antigen-Antibody Complex; Complement Activation; Complement C4; Humans; Hydralazine; Immune Complex Diseases; Lupus Erythematosus, Systemic; Molecular Sequence Data; Penicillamine; Procainamide

1991
The role of complement in the aetiopathogenesis of systemic lupus erythematosus.
    Autoimmunity, 1991, Volume: 11, Issue:1

    Topics: Antigen-Antibody Complex; Complement Pathway, Classical; Complement System Proteins; HLA Antigens; Humans; Hydralazine; Immune Complex Diseases; Isoniazid; Lupus Erythematosus, Systemic; Major Histocompatibility Complex; Penicillamine

1991
Drug-induced immune-complex disease.
    Complement and inflammation, 1989, Volume: 6, Issue:2

    Topics: Humans; Hydralazine; Immune Complex Diseases; Isoniazid; Lupus Erythematosus, Systemic; Penicillamine; Practolol; Procainamide

1989
[Drug-induced lupus].
    Recenti progressi in medicina, 1985, Volume: 76, Issue:2

    Topics: Acetylation; Adrenergic beta-Antagonists; Antibodies, Antinuclear; Anticonvulsants; B-Lymphocytes; Diagnosis, Differential; HLA Antigens; Humans; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Lymphocyte Activation; Penicillamine; Procainamide; Sulfasalazine; T-Lymphocytes, Regulatory

1985
Drug-induced autoimmune disease.
    Advances in nephrology from the Necker Hospital, 1987, Volume: 16

    Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Gold; HLA Antigens; Humans; Hydralazine; Lupus Erythematosus, Systemic; Penicillamine

1987
Lupus-like syndromes induced by drugs.
    Annals of allergy, 1974, Volume: 33, Issue:5

    Topics: Antibodies, Antinuclear; Antibody Formation; Arthritis, Rheumatoid; Chlorpromazine; DNA, Single-Stranded; Drug-Related Side Effects and Adverse Reactions; False Positive Reactions; Female; Fluorescent Antibody Technique; Glucocorticoids; Humans; Hydralazine; Isoantigens; Isoniazid; Lupus Erythematosus, Systemic; Lymphocyte Activation; Male; Neutrophils; Nucleoproteins; Penicillamine; Phenytoin; Procainamide; Remission, Spontaneous; Syphilis Serodiagnosis

1974

Trials

1 trial(s) available for penicillamine and hydralazine

ArticleYear
Treatment of generalized scleroderma with inhibitors of connective tissue formation.
    Acta dermato-venereologica, 1975, Volume: 55, Issue:6

    Topics: Adult; Age Factors; Clinical Trials as Topic; Connective Tissue; Depression, Chemical; Dextrothyroxine; Drug Interactions; Female; Glucocorticoids; Humans; Hydralazine; Male; Middle Aged; Penicillamine; Penicillins; Scleroderma, Systemic; Time Factors

1975

Other Studies

22 other study(ies) available for penicillamine and hydralazine

ArticleYear
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
[Molecular aspects of disorders in fibrillogenesis of connective tissue caused by medicinal ligands].
    Doklady Akademii nauk SSSR, 1979, Jun-11, Volume: 246, Issue:5

    Topics: Animals; Connective Tissue; Humans; Hydralazine; Isoniazid; Penicillamine; Phenytoin; Procainamide; Protein-Lysine 6-Oxidase

1979
[Molecular aspects of connective tissue fibrillogenesis disorders caused by drug ligands].
    Doklady Akademii nauk SSSR, 1979, Volume: 246, Issue:5

    Topics: Animals; Chemical Phenomena; Chemistry; Collagen; Collagen Diseases; Elastin; Humans; Hydralazine; Isoniazid; Ligands; Penicillamine; Phenytoin; Procainamide; Protein-Lysine 6-Oxidase

1979
Treatment of generalized scleroderma: updated results.
    Acta dermato-venereologica, 1979, Volume: 59, Issue:5

    Topics: Chlorpromazine; Collagen; Drug Evaluation; Glutamine; Glycosaminoglycans; Humans; Hydralazine; Levodopa; Penicillamine; Penicillin G; Phenytoin; Prednisone; Scleroderma, Systemic

1979
Effect of penicillamine, hydrallazine and phenelzine on the function of pyridoxal-5'-phosphate [proceedings].
    British journal of pharmacology, 1979, Volume: 67, Issue:3

    Topics: Animals; Hydralazine; Penicillamine; Phenelzine; Pyridoxal Phosphate; Rats

1979
[Drug-induced disorders of lupus erythematosus type (author's transl)].
    Arzneimittel-Forschung, 1977, Volume: 27, Issue:96

    Topics: Animals; Antibody Formation; Anticonvulsants; Chlorpromazine; Drug-Related Side Effects and Adverse Reactions; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Penicillamine; Procainamide; Rats

1977
[Treatment of generalized scleroderma with connective tissue inhibitors].
    Ugeskrift for laeger, 1976, May-24, Volume: 138, Issue:22

    Topics: Adrenal Cortex Hormones; Adult; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydralazine; Male; Middle Aged; Penicillamine; Penicillin G Procaine; Prognosis; Scleroderma, Systemic; Thyroxine

1976
Comparison of the inhibitory potencies of N(G)-methyl-, N(G)-nitro- and N(G)-amino-L-arginine on EDRF function in the rat: evidence for continuous basal EDRF release.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 257, Issue:3

    Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Blood Pressure; Hydralazine; In Vitro Techniques; Male; Nitrates; Nitric Acid; Nitric Oxide; Nitroarginine; omega-N-Methylarginine; Penicillamine; Phenylephrine; Rats; Rats, Inbred Strains; S-Nitroso-N-Acetylpenicillamine; Sympathetic Nervous System; Vasodilation; Vasopressins

1991
Antibodies to the five histones and poly(adenosine diphosphate-ribose) in drug induced lupus: implications for pathogenesis.
    Annals of the rheumatic diseases, 1987, Volume: 46, Issue:5

    Topics: Antibodies, Antinuclear; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemic; Nucleoside Diphosphate Sugars; Penicillamine; Poly Adenosine Diphosphate Ribose; Sulfasalazine

1987
Effects of lupus-inducing drugs on the B to Z transition of synthetic DNA.
    Arthritis and rheumatism, 1986, Volume: 29, Issue:5

    Topics: Canavanine; Circular Dichroism; DNA; Hydralazine; Isoniazid; Lupus Erythematosus, Systemic; Nucleic Acid Conformation; Penicillamine; Polydeoxyribonucleotides; Procainamide

1986
The diagnostic value of antihistone antibodies in drug-induced lupus erythematosus.
    Arthritis and rheumatism, 1985, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aged; Antibodies, Antinuclear; Autoantibodies; Child; Disopyramide; Female; Fluorescent Antibody Technique; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemic; Male; Middle Aged; Penicillamine; Phenytoin; Procainamide

1985
[Kidney diseases caused by drugs].
    Deutsche medizinische Wochenschrift (1946), 1967, Sep-08, Volume: 92, Issue:36

    Topics: Acute Kidney Injury; Adult; Anemia; Arthritis, Rheumatoid; Dextrans; Drug-Related Side Effects and Adverse Reactions; Fanconi Syndrome; Female; Glomerulonephritis; Hepatolenticular Degeneration; Humans; Hydralazine; Kidney Diseases; Kidney Failure, Chronic; Male; Methysergide; Middle Aged; Nephrotic Syndrome; Penicillamine; Phenacetin; Potassium Deficiency; Retroperitoneal Fibrosis; Sulfonamides; Tetracycline

1967
Drug effects on autoantibodies and immune complexes.
    Agents and actions. Supplements, 1980, Volume: 7

    Topics: Acetylation; Antibodies, Antinuclear; Antigen-Antibody Complex; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Binding Sites; Complement C1; Humans; Hydralazine; Immunoglobulin M; Lupus Erythematosus, Systemic; Methyldopa; Penicillamine; Procainamide; Rheumatoid Factor

1980
The heterogeneity of serologic findings and predisposing host factors in drug-induced lupus erythematosus.
    Arthritis and rheumatism, 1981, Volume: 24, Issue:8

    Topics: Acetylation; Antibodies, Antinuclear; Antilymphocyte Serum; Arthritis, Rheumatoid; Complement Fixation Tests; Female; Histocompatibility Antigens Class II; Humans; Hydralazine; Keratoconjunctivitis; Lupus Erythematosus, Systemic; Male; Penicillamine; Time Factors

1981
Treatment of generalized scleroderma with inhibitors of collagen synthesis.
    International journal of dermatology, 1982, Volume: 21, Issue:3

    Topics: Catechin; Chlorpromazine; Collagen; Dextrothyroxine; Glutamine; Humans; Hydralazine; Levodopa; Penicillamine; Penicillin G; Phenytoin; Prednisone; Scleroderma, Systemic

1982
Regulation of lysyl oxidase mRNA in dermal fibroblasts from normal donors and patients with inherited connective tissue disorders.
    Archives of biochemistry and biophysics, 1994, Volume: 308, Issue:1

    Topics: Aminopropionitrile; Ascorbic Acid; Bleomycin; Cell Line; Collagen; Connective Tissue Diseases; DNA Probes; DNA, Complementary; Female; Fibroblasts; Gene Expression Regulation, Enzymologic; Humans; Hydralazine; Kinetics; Male; Minoxidil; Penicillamine; Pregnancy; Protein-Lysine 6-Oxidase; Reference Values; RNA, Messenger; Skin

1994
Regional and cardiac haemodynamic effects of NG, NG,dimethyl-L-arginine and their reversibility by vasodilators in conscious rats.
    British journal of pharmacology, 1993, Volume: 110, Issue:4

    Topics: Animals; Arginine; Glutathione; Hemodynamics; Hydralazine; Male; Nitroprusside; Nitroso Compounds; omega-N-Methylarginine; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Vasodilator Agents

1993
Granulocyte autoantibodies--markers for drug-induced autoimmune adverse effects.
    Clinical nephrology, 1993, Volume: 39, Issue:5

    Topics: Antibodies, Antineutrophil Cytoplasmic; Autoantibodies; Autoimmune Diseases; Biomarkers; Glomerulonephritis; Humans; Hydralazine; Penicillamine

1993
Role of nitric oxide and prostaglandins in mechanically induced bone formation.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1998, Volume: 13, Issue:6

    Topics: Animals; Blotting, Northern; Bone Development; Coccyx; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Genes, fos; Glutathione; Hydralazine; Indomethacin; Nitric Oxide; Nitroso Compounds; omega-N-Methylarginine; Penicillamine; Prostaglandins; Rats; Rats, Wistar; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; Vasodilator Agents; Weight-Bearing

1998
Drug-associated antineutrophil cytoplasmic antibody-positive vasculitis: prevalence among patients with high titers of antimyeloperoxidase antibodies.
    Arthritis and rheumatism, 2000, Volume: 43, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Antibodies; Antibodies, Antineutrophil Cytoplasmic; Female; Humans; Hydralazine; Male; Middle Aged; Penicillamine; Peroxidase; Propylthiouracil; Sulfasalazine; Vasculitis

2000
Covalent binding of penicillamine to macrophages: implications for penicillamine-induced autoimmunity.
    Chemical research in toxicology, 2009, Volume: 22, Issue:7

    Topics: Aldehydes; Animals; Autoimmunity; Biotin; Hydralazine; Macrophages; Male; Penicillamine; Protein Binding; Proteins; Rats; Rats, Inbred BN; Schiff Bases

2009