penicillamine has been researched along with cysteine in 336 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 191 (56.85) | 18.7374 |
| 1990's | 73 (21.73) | 18.2507 |
| 2000's | 51 (15.18) | 29.6817 |
| 2010's | 17 (5.06) | 24.3611 |
| 2020's | 4 (1.19) | 2.80 |
| Authors | Studies |
|---|---|
| DeMaster, EG; Goon, DJ; Nagasawa, HT | 1 |
| Cheng, JP; Wang, K; Wang, PG; Wen, Z; Xian, M; Zhang, W | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Kuntz, RR; Wu, JT | 1 |
| Otomo, S; Sasajima, M; Takahashi, K; Tanaka, I | 1 |
| Lange, K | 1 |
| Mason, J; McGivern, J | 1 |
| Stephens, AD | 1 |
| Purkiss, P; Watts, RW | 1 |
| Fenton, JC; Stephens, AD | 1 |
| Crawhall, JC | 1 |
| Crawhall, JC; Oshima, RG; Schneider, JA; Thoene, JG | 1 |
| Brown, DH; Smith, WE | 1 |
| Perrett, D | 1 |
| Chen, SN; Hoffman, MZ | 1 |
| Chatagner, F; Portemer, C | 1 |
| Jordan, RB; Letter, JE | 1 |
| Schonbeck, ND; Shafer, JA; Skalski, M | 1 |
| Finley, JW; Friedman, M; Snow, JT | 2 |
| Maini, RN; Roffe, L; Room, G | 1 |
| Ament, HJ; Henrichs, AM; Muijsers, AO; Van De Stadt, RJ; Van Der Korst, JK | 2 |
| Chwaliński, S; Krzystyniak, K; Ryzewski, J | 1 |
| Ishaque, M; Kato, L | 1 |
| Donahe, S; Janauer, GE; Lewkowicz, C; Zucconi, TD | 1 |
| Emerit, I; Emerit, J; Keck, M; Levy, A | 1 |
| Friedman, M; Noma, AT; Wagner, JR | 1 |
| Garnier, A; Tosi, L | 1 |
| Alexander, CS; DeMaster, EG; Goon, DJ; Nagasawa, HT | 1 |
| Johannsen, B; Münze, R; Spies, H; Syhre, R | 1 |
| Kanno, Y; Muneoka, Y; Shiba, Y; Yamami, T | 1 |
| Nigrovic, V | 1 |
| Clarkson, TW; Magos, L | 1 |
| Baum, J; Chwalinska-Sadowska, H | 1 |
| Cederbaum, AI; Rubin, E | 1 |
| Aaseth, J | 1 |
| Akopyan, TN; Braunstein, AE; Goryachenkova, EV | 1 |
| Abbasi, AH; Cestero, RV; Clarkson, TW; Freeman, RB; Kostyniak, PJ | 1 |
| Kretzschmar, R; Worstmann, W | 1 |
| Alexander, CS; Constantino, NV; Goon, DJ; Nagasawa, HT | 1 |
| Funakoshi, T; Kiyozumi, M; Kojima, S; Shimada, H; Takahashi, Y | 1 |
| Benov, LC; Monovich, OH; Ribarov, SR | 1 |
| Ichimori, Y; Kondo, K; Ohkawa, S; Okishio, M | 1 |
| Kiyozumi, M; Kojima, S; Tagawa, Y; Takahashi, Y | 1 |
| Arimori, S; Ichikawa, Y; Shimizu, H | 1 |
| García-López, MT; Herranz, R; Pérez, C | 1 |
| Hayashi, M; Matsunaga, K; Mita, S; Okahara, A | 1 |
| Becker, D; Sevilla, MD; Yan, M | 1 |
| Khan, MF; Sorenson, JR | 1 |
| Denneberg, T; Lindell, A; Mårtensson, J; Textorius, O | 1 |
| Matsunaga, K; Mita, S | 1 |
| Glatt, H; Herbst, M; Oesch, F; Utesch, D | 1 |
| Hayashi, M; Iso, T; Kasamatsu, S; Nakata, K; Sasano, M; Suda, H; Yamauchi, H | 1 |
| Bonnefont, JP; Charpentier, C; Kamoun, P; Parvy, P; Saudubray, JM; Tardy, P | 1 |
| Bast, A; Haenen, GR; Timmerman, H; Vermeulen, NP | 1 |
| Arad, A; Pagano, DA; Siskindovich, S; Stark, AA; Zeiger, E | 1 |
| Casas, JS; Filella, M; García Bugarín, M; Sordo, J | 1 |
| Andrews, JC; Bavister, BD | 1 |
| Dodds, AW; Goldin, A; Sim, E | 1 |
| Becker, D; Champagne, M; Sevilla, MD; Swarts, S | 1 |
| Bird, HA; Dixon, JS; Martin, MF; McKenna, F; Wright, V | 1 |
| Ishikawa, K; Sakaguchi, M | 1 |
| Mason, RP; Mottley, C; Toy, K | 1 |
| Pilkington, AE; Waring, RH | 1 |
| Nicholson, JK; Walshe, JA; Wilson, ID | 1 |
| Aoyama, E; Chikuma, M; Kobayashi, N; Nakagawa, T; Nakayama, M; Sakurai, H; Tanaka, H | 1 |
| Howell, SB; Velury, S | 1 |
| Hammond, JW; Sampson, DC; Stewart, PM | 1 |
| Ammon, HP; Enz, G; Hehl, KH; Setiadi-Ranti, A; Verspohl, EJ | 1 |
| Refsvik, T | 5 |
| Elberling, JE; Nagasawa, HT; Roberts, JC | 1 |
| Baker, LR; Greenwood, RN; Matthey, F; Perrett, D | 1 |
| Abe, C; Hayashi, M; Iso, T; Nozawa, RT; Shiokawa, Y; Yokota, T | 1 |
| Beyer, J; Boesen, PD; Helin, P; Hørslev-Petersen, K | 1 |
| Glatt, H; Oesch, F | 1 |
| Anderson, CH; Holwerda, RA | 1 |
| Messner, RP; Staite, ND; Zoschke, DC | 1 |
| Fujimura, K; Hikida, M; Horiuchi, M; Iso, T; Kuwano, M; Morikawa, K; Uemura, O; Yamauchi, H | 1 |
| de Weck, AL; Pfeuti, C; Schneider, CH | 1 |
| Jókay, I; Kassay, L; Kiss, A | 1 |
| Axelsson, H; Johansson, BG; Rymo, L | 1 |
| Schmid, A | 2 |
| Körber, F; Margraf-Modersohn, D; Siegmund, P | 1 |
| Blumberg, WE; Peisach, J | 1 |
| Mauermayer, W; Wenzl, H | 1 |
| Cambie, E; Feher, J; Francois, J; Van Den Eeckhout, E | 1 |
| Berman, MB; Manabe, R | 1 |
| Moser, P; Verzár, F | 1 |
| Ehrenfeld, E; Jaffe, IA; Merryman, P | 1 |
| Pestaña, A; Sandoval, IV; Sols, A | 1 |
| Aposhian, HV | 2 |
| Asakura, S; Nagamori, S; Okamura, S; Oya, M; Toshioka, N | 1 |
| Schütt, A; Siegers, CP; Strubelt, O | 1 |
| Dörl, F; Faur, A; Păsculescu, G | 1 |
| Kallistratos, G; Malorny, G | 1 |
| Friedman, M; Masri, MS; Noma, AT | 1 |
| Butler, M; Giannina, T; Steinetz, B | 1 |
| Kuntz, RR; Tung, TL | 2 |
| Thomas, G; West, GB | 1 |
| Fels, H; Rauen, HM; Schriewer, H | 1 |
| Kuzel, K | 1 |
| Planas-Bohne, F | 1 |
| Planas-Bohne, F; Polig, E | 1 |
| Dietze, F; Lisewski, G; Reitzig, P; Schulz, HJ | 1 |
| Denneberg, T; Ekberg, M; Jeppsson, JO | 1 |
| Bradley, KH; Schulman, JD | 1 |
| Demopoulos, HB; Hourani, BT | 1 |
| Hoppe, D; Schöllkopf, U | 1 |
| Langenfeld, R | 1 |
| Pesek, JJ; Sudmeier, JL | 1 |
| Hollinger, HZ; Kisil, FT; Sehon, AH | 1 |
| Catalanotto, FA; Henkin, RI | 1 |
| Kasuya, M | 1 |
| Breitmaier, E; Flohé, L; Günzler, WA; Jung, G; Voelter, W | 1 |
| Braunstein, AE; Goryachenkova, EV; Tolosa, EA; Willhardt, IH; Yefremova, LL | 1 |
| Budke, L; Vergroesen, AJ; Vos, O | 1 |
| Christensen, MF; Henriksen, O; Nielsen, JA | 1 |
| Lapière, CM; Van Caneghem, P | 1 |
| Calick, A; Fabianek, J; Herp, A; Pigman, W | 1 |
| Békési, I; Hernádi, F; Kovács, P; Nagy, Z | 1 |
| Bacon, VA; Halpern, B; Jellum, E; Patton, W; Pereira, W | 1 |
| Alexander, M; Kludas, M | 1 |
| Corrocher, R; Cortesi, S; De Sandre, G; Falezza, G; Perona, G | 1 |
| Hirayama, K; Takahashi, H | 1 |
| Evered, DF; Wass, M | 1 |
| Chang, CC; Lorber, A; Masuoka, D; Meacham, I | 1 |
| Blahd, W; Krishnamurthy, GT; Lederer, M; Tubis, M | 1 |
| Stephens, AD; Watts, RW | 1 |
| Loddo, B; Mazzucato, P; Tagliamonte, A | 1 |
| Doornbos, DA | 3 |
| Crawhall, JC; Lietman, PS; Schneider, JA; Seegmiller, JE | 1 |
| DeMoss, RD; Gopinathan, KP | 1 |
| Copeland, W; Kelly, S | 1 |
| Harkness, RD; Nimni, ME | 1 |
| Corrocher, R; Cortesi, S; De Sandre, G; Perona, G; Vettore, L | 1 |
| Kimura, ET; Klamer, B; Makstenieks, M | 1 |
| Aboulker, P; Balan, A; Charpentier, C; Leluc, R; Lemonnier, A; Levillain, L; Thomas, J; Thuong, CT | 1 |
| Körber, F; Modersohn, D; Siegmund, P | 1 |
| Hasenbank, G; Körber, F; Siegmund, P | 1 |
| Gravelle, RA; Hanafi, DE; Purdie, JW | 1 |
| Boyde, TR | 1 |
| Kosaka, S | 1 |
| Anderson, AJ | 1 |
| Bradley, KH; Crawhall, JC; Thompson, CJ | 1 |
| Geever, EF; Levenson, SM; Seifter, E; Youssef, S | 1 |
| Boström, H; Wester, PO | 1 |
| Degroot, LJ | 1 |
| Mattok, GL | 1 |
| Doornbos, DA; Feitsma, MT | 1 |
| Tappel, AL | 1 |
| Kostyniak, PJ | 1 |
| Emery, P; Huston, G; Idle, JR; Mitchell, SC; Panayi, GS; Shah, RR; Smith, RL; Waring, RH; Welsh, KI | 1 |
| Goto, K; Hisadome, M; Kawazoe, Y; Tsumagari, T | 1 |
| Aihara, H; Nakaike, S; Otomo, S; Tanaka, C; Tomita, N; Umemoto, M | 1 |
| Breckenridge, AM; Park, BK; Yeung, JH | 1 |
| Asmus, KD; Bonifacić, M | 1 |
| Abd-Elfattah, AS; Shamoo, AE | 1 |
| Johnson, S; Kaung, C; Roboz, J; Yu, TF | 1 |
| Haley, CS; Idle, JR; Mitchell, SC; Smith, RL; Waring, RH | 1 |
| Butler, M; Carruthers, G; Freeman, D; Harth, M; Rothwell, R; Weir, D | 1 |
| Ballatori, N; Clarkson, TW | 1 |
| Gergely, A; Sóvágó, I | 1 |
| Asper, R; Schmucki, O | 1 |
| Inoue, K; Kyogoku, K; Noda, K; Ohzeki, M; Otake, T | 1 |
| Grasedyck, K; Lindner, J; Meyer, F; Peters, K | 1 |
| Ohmori, H; Okimura, T; Yamamoto, I | 1 |
| Gruber, C; Gruber, DK; Lent, R; Levenson, SM; Seifter, E | 1 |
| Cain, K; Skilleter, DN | 1 |
| Domer, FR; Hellstrom, WJ; Kadowitz, PJ; Sikka, SC; Wang, R | 1 |
| Beck, JK; Kojda, G; Meyer, W; Noack, E | 1 |
| Harris, N; Karupiah, G | 1 |
| Koivisto, A; Nedergaard, J | 1 |
| Beauvais, F; Dubertret, L; Michel, L | 1 |
| Brooks, P; Conaghan, PG | 1 |
| Fairclough, RH; Richman, DP; Xu, Q | 1 |
| Fujisaki, T; Hou, H; Nakamura, K; Nakano, A; Yamamoto, M; Yasutake, A | 1 |
| Ozawa, T; Shimazu, Y; Ueda, J | 1 |
| Bina, S; Hart, JL; Muldoon, SM | 1 |
| Gustafsson, LE; Iversen, HH; Leone, AM; Wiklund, NP | 1 |
| Brooks, P; Conaghan, PG; Girgis, L | 1 |
| Lenhart, A; Mao, Y; Shi, X | 1 |
| Hirohata, S; Lipsky, PE | 2 |
| Barbier, AJ; Lefebvre, RA | 1 |
| Dalal, NS; Dong, Z; Gannett, PM; Shi, X | 1 |
| Coles, B; Ketterer, B; Kramer, H; Meyer, DJ; Ozer, N | 1 |
| Akamatsu, T; Matsubara, T; Mizuno, K; Saegusa, Y | 1 |
| Keire, DA; Mariappan, SV; Peng, J; Rabenstein, DL | 1 |
| Bolgar, M; Hunt, JT; Lee, VG; Liu, EC; McMullen, D; Moreland, S; Webb, ML | 1 |
| Li, CG; Rand, MJ | 1 |
| Hirohata, S; Inoue, T; Ito, K; Iwamoto, S; Kawashima, C; Kisaki, T; Nishioka, Y; Sawada, T; Shinohara, S; Tohma, S | 1 |
| Doyle, DV; Ensor, M; Foster, OJ; Perrett, D; Scott, DL | 1 |
| Dalal, NS; Kasprzak, KS; Shi, X | 1 |
| Lopez Garcia, I; Martinez Gil, JA; Viñas, P | 1 |
| George, MJ; Shibata, EF | 1 |
| Lock, EA | 1 |
| Askew, SC; Butler, AR; Flitney, FW; Kemp, GD; Megson, IL | 1 |
| Aposhian, HV; Maiorino, RM; Xu, ZF | 1 |
| Hogg, N; Joseph, J; Kalyanaraman, B; Karoui, H | 1 |
| Constantine-Paton, M; Rentería, RC | 1 |
| Correa, JG; Stoppani, AO | 1 |
| Day, RO; Handel, ML; Sivertsen, S; Sutherland, RL; Watts, CK | 1 |
| Bates, JN; Holmes, RW; Snyder, GD; Van Voorhis, BJ | 1 |
| Kimura, T; Miyazaki, H; Murayama, T; Narita, H; Nomura, Y; Ono, S; Satoh, S; Toda, M | 1 |
| Wroński, M | 1 |
| Abdel-Rahman, SZ; Ahmed, AE; Nouraldeen, AM; Rajaraman, S | 1 |
| Adachi, K; Aoki, T; Hara, J; Kitano, A; Kobayashi, K; Matsumoto, T; Nakamura, S; Obata, A; Obayashi, M; Okabe, H; Okawa, K; Oshitani, N; Suzuki, N; Tabata, A; Watanabe, Y; Yasuda, K | 1 |
| Bonfoco, E; Leist, M; Lipton, SA; Nicotera, P; Orrenius, S; Zhivotovsky, B | 1 |
| Balint, GA | 1 |
| Kim, HA; Song, YW | 1 |
| Alexander, PW; Hibbert, DB; Hidayat, A | 1 |
| Bernassola, F; Corasaniti, MT; Finazzi-Agro, A; Knight, RA; Melino, G; Nistico, G | 1 |
| Brorson, JR; Zhang, H | 1 |
| D'Souza, SW; Lees, RD; Slater, P | 1 |
| Hefter, GT; May, PM; Tran-Ho, LC | 1 |
| Gryglewski, RJ; Marcinkiewicz, E; Michalska, Z; Robak, J | 1 |
| Cheung, PY; Danial, H; Jong, J; Schulz, R | 1 |
| Graves, JE; Kooy, NW; Lewis, SJ | 1 |
| Kubo, T; Matsuno, H; Matsuura, K; Muraguchi, A; Nezuka, T; Sugiyama, E; Tsuji, H | 1 |
| Beauvais, F; Joly, F | 1 |
| Burner, U; Jantschko, W; Obinger, C | 1 |
| Frölich, JC; Gutzki, FM; Rossa, S; Sandmann, J; Tsikas, D | 1 |
| Darley-Usmar, VM; Hogg, N; Kalyanaraman, B; Matalon, S; Patel, RP; Spencer, NY | 1 |
| Hata, F; Ishii, T; Nakajima, H; Nishio, H; Sunami, O; Takeuchi, T | 1 |
| Bogdanowich-Knipp, SJ; Chakrabarti, S; Dillman, RK; Siahaan, TJ; Williams, TD | 1 |
| Metodiewa, D; Winterbourn, CC | 1 |
| Imai, N; Ishihara, N; Miyata, K; Nozaki, H; Terayama, Y | 1 |
| Coe, FL; Nakagawa, Y | 1 |
| Barnes, S; Hirooka, K; Kourennyi, DE | 1 |
| Kumagai, S; Morinobu, A; Wang, Z | 1 |
| Aono, H; Horiuchi, M; Matsuoka, H; Mita, S; Nishimura, K; Takai, M; Tsuji, F | 1 |
| Hirata, D; Iwamoto, M; Kamimura, T; Kano, S; Masuyama, JI; Mimori, A; Minota, S; Okazaki, H; Sato, H; Yoshio, T | 1 |
| Esler, MD; Gruskin, S; Kaye, DM; Smith, AI | 1 |
| Dongre, N; Eisenach, JC; Li, X; Pan, HL; Rose, G; Tobin, JR | 1 |
| Chong, CR; Joshua-Tor, L; van Aalten, DM | 1 |
| Badorff, C; Dimmeler, S; Fichtlscherer, B; Knowlton, KU; Muelsch, A; Rhoads, RE; Zeiher, AM | 1 |
| Chen, SR; Eisenach, JC; Pan, HL | 1 |
| Choi, EJ; Huh, SH; Kim, MS; Lee, SH; Park, HS | 1 |
| Hansen, L; Hirota, S; Marzilli, LG; Taylor, AT; Xu, X | 1 |
| Sissons, CH; Yakub, S | 1 |
| Basu, A; Lander, HM; Ogiste, JS; Sehajpal, PK | 1 |
| Donoghue, JF; Kwek, K; Read, MA; Walters, WA; Zhang, XQ | 1 |
| Fukushima, K; Inoue, T; Takeshita, K | 1 |
| Artz, JD; Bennett, BM; Thatcher, GR; Toader, V; Zavorin, SI | 1 |
| Hayes, EL; Kanterewicz, BI; Klann, E; Knapp, LT | 1 |
| Buxton, IL; Kaiser, RA; Malmquist, NA; Tichenor, S | 1 |
| Choi, EJ; Kang, SI; Kim, IY; Kim, JY; Park, HS | 1 |
| La Spada, G; Marino, A; Montaleone, B; Musci, G; Soffli, A; Sorrenti, G | 1 |
| Campiglia, P; Carotenuto, A; Grieco, P; Maggi, CA; Novellino, E; Patacchini, R; Rovero, P; Zampelli, E | 1 |
| Inoue, T; Nakaike, S; Sugimoto, M; Takeshita, K; Yamashita, M | 1 |
| EISEN, HN; LEVINE, B; TABACHNICK, M | 1 |
| DU VIGNEAUD, V; KUCHINSKAS, EJ | 1 |
| DU VIGNEAUD, V; HORVATH, A; KUCHINSKAS, EJ | 2 |
| APOSHIAN, HV; RHEA, WG; WOLFF, SM | 1 |
| BAKER, RA; BOULDING, JE; FISTER, WP | 1 |
| OSBORN, SB; WALSHE, JM | 1 |
| APOSHIAN, HV; BLAIR, RM | 1 |
| HARRIS, CE | 1 |
| KLIMAN, B; PETERSON, RE; SEVEN, MJ | 1 |
| APOSHIAN, HV; APOSHIAN, MM | 1 |
| LEVINE, BB | 1 |
| HARTLEY, BS; WALSHE, JM | 1 |
| MACKAY, D | 1 |
| CONTRACTOR, SF | 1 |
| DOORNBOS, DA; FABER, JS | 2 |
| MUELLER, OH | 1 |
| AKERFELDT, S; LOEVGREN, G | 1 |
| LENZ, GR; MARTELL, AE | 1 |
| TRUSCOE, R | 1 |
| CRAWHALL, JC; THOMPSON, CJ | 1 |
| BOYCE, WH; KING, JS | 1 |
| COLLINI, WR; HARRIS, RC; MATTERN, SR; SHAPIRO, P; ZINSSER, HH | 1 |
| PATRICK, AD | 1 |
| HAANEN, CA; JANSEN, AP; MAJOOR, CL; SEIGNETTE, WT | 1 |
| Cho, JH; Choi, EJ; Huh, SH; Kim, MS; Park, HS; Ryoo, K; Yu, JW | 1 |
| Griesbeck, AG; Heckroth, H | 1 |
| Koppenol, WH; Papina, AA; Serezhenkov, VA; Vanin, AF | 1 |
| Ckless, K; Guala, AS; Janssen-Heininger, YM; Korn, SH; Reynaert, NL; van der Vliet, A; Vos, N; Wouters, EF | 1 |
| Harris, RM; Mitchell, SC; Roopnarinsingh, ES; Steventon, GB; Waring, RH | 1 |
| Costello, AL; Gibney, BR; Petros, AK; Shaner, SE; Tierney, DL | 1 |
| Jordan, RB; McDonald, R; Sisley, MJ | 1 |
| Calhorda, MJ; Cavaco, I; Correia, I; Costa, D; Costa, PJ; Félix, V; Gillard, RD; Henriques, RT; Pessoa, JC; Vilas-Boas, LF; Wiggins, R | 1 |
| Cao, XN; Jin, LT; Li, JH; Lin, L; Xian, YZ; Xu, HH; Yamamoto, K | 1 |
| Ohno, I | 1 |
| Kaneki, M; Martyn, JA; Ota, H; Sugita, H; Tokunaga, E; Yasukawa, T | 1 |
| Frost, MC; Meyerhoff, ME | 1 |
| Asplin, JR; Dolin, DJ; Flagel, L; Goldfarb, DS; Grasso, M | 1 |
| Cheah, J; Han, Y; Huang, Y; Huganir, RL; Juluri, K; Lowenstein, C; Luo, H; Man, HY; Sekine-Aizawa, Y; Snyder, SH | 1 |
| Aoyama, M; Asai, K; Fukuoka, M; Kobayashi, M; Kusabe, T; Otsuka, T; Tanikawa, T; Waguri-Nagaya, Y | 1 |
| Harris, RM; Mitchell, SC; Roopnarinesingh, ES; Steventon, GB; Waring, RH | 1 |
| Aikath, D; Chattopadhyay, I; Das, SK; Gangopadhyay, PK; Gupta, A; Hashmi, MA; Ray, K | 1 |
| Berezné, A; Guillevin, L; Mouthon, L; Poiraudeau, S | 1 |
| Akizawa, T; Koshikawa, S; Kuroki, A | 1 |
| Goldstein, S; Merenyi, G; Samuni, A | 1 |
| Bhushan, R; Kumar, R | 1 |
| Mimori, T; Yukawa, N | 1 |
| Jalilehvand, F; Leung, BO; Pettersson, LG; Risberg, ED; Sandström, M | 1 |
| Jalilehvand, F; Leung, BO; Mah, V | 1 |
| Igashira-Kamiyama, A; Kawamoto, T; Konno, T; Tamura, M; Tsuge, K; Yamagishi, M | 1 |
| Perkel, JM | 1 |
| Igashira-Kamiyama, A; Konno, T; Sameshima, Y; Tsuge, K; Yoshinari, N | 1 |
| Igashira-Kamiyama, A; Kawamoto, T; Konno, T; Seko, H; Tsuge, K | 1 |
| Myerson, AS; Singh, A | 1 |
| GRANT, GA; RICHARDSON, EM; SAVARD, K | 1 |
| Carru, C; Deiana, L; Pinna, GA; Sotgia, S; Zinellu, A | 2 |
| Bhushan, R; Dubey, R | 1 |
| Baňasová, M; Hrabárová, E; Juránek, I; Nagy, M; Priesolová, E; Soltés, L; Valachová, K | 1 |
| Chiotellis, A; Papadopoulos, M; Pelecanou, M; Pirmettis, I; Tsoukalas, C | 1 |
| Ianni, F; Natalini, B; Sardella, R | 1 |
| Jalilehvand, F; Leung, BO; Mah, V; Parvez, M; Wu, Q | 1 |
| Guo, XF; Tu, FQ; Wang, H; Wang, P; Zhang, HS; Zhang, LY | 1 |
| Byrne, C; Devi, P; Houlihan, KM; Jensen, P; Rutledge, PJ | 1 |
| Hefter, G; Königsberger, E; Königsberger, LC; May, PM | 1 |
| Wu, C; Zhai, L; Zhao, Y; Zheng, Y | 1 |
| Grenács, Á; Lihi, N; Sóvágó, I; Várnagy, K | 1 |
| Lin, P; Wu, C; Yao, H; Zha, M; Zhao, Y | 1 |
| Ghasemi, F; Hormozi-Nezhad, MR; Shahrajabian, M | 1 |
| Chen, Z; Jin, K; Li, J; Li, X; Liu, J; Tan, Y; Yang, J | 1 |
| Aryanian, Z; Daneshpazhooh, M; Etesami, I; Ghaedi, F; Goodarzi, A; Kalantari, Y; Mahmoudi, H; Tavakolpour, S; Teymourpour, A | 1 |
| Li, X; Liu, J | 1 |
| Alharthi, NS; Arain, SP; Eltayeb, LB; Khan, H; Mangi, AA; Shaikh, ZA; Siyal, FJ | 1 |
| Chen, JM; Du, M; Du, X; Laakso, LM; Levin, JI; Sandanayaka, V; Skotnicki, JS; Venkatesan, AM; Xu, J; Xu, W; Zask, A; Zhang, Y | 1 |
| Audic, N; Ermolenko, L; Franck, G; Garcia-Alvarez, MC; Martin, MT; Nhiri, N; Potier, P; Sasaki, NA; Wang, Q | 1 |
15 review(s) available for penicillamine and cysteine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
The management of cystinuria in 1976.
Topics: Cysteine; Humans; Penicillamine; Proteinuria | 1977 |
Canadian experience with penicillamine therapy for cystinuria.
Topics: Adolescent; Adult; Canada; Cysteine; Female; Humans; Male; Penicillamine; Proteinuria | 1977 |
Cystine depletion of cystinotic cells by aminothiols.
Topics: Cell-Free System; Cystamine; Cysteamine; Cysteine; Cystinosis; Fibroblasts; Humans; Penicillamine; Sulfhydryl Compounds | 1977 |
Complexes of L-cysteine and D-penicillamine with gold (I) and (III).
Topics: Cysteine; Gold; Penicillamine | 1977 |
"Yellow nail syndrome" and rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Middle Aged; Nail Diseases; Nails; Penicillamine; Syndrome | 1991 |
Penicillamine and analogous chelating agents.
Topics: Acetates; Amino Acid Oxidoreductases; Animals; Chelating Agents; Copper; Cysteine; D-Amino-Acid Oxidase; Female; Hepatolenticular Degeneration; Humans; Lethal Dose 50; Liver; Lyases; Mercury Poisoning; Penicillamine; Rats; Species Specificity; Stereoisomerism; Venoms | 1971 |
Disease-modifying antirheumatic drugs, including methotrexate, gold, antimalarials, and D-penicillamine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Drug Therapy, Combination; Gold; Humans; Methotrexate; Penicillamine; Sulfasalazine | 1995 |
Disease-modifying antirheumatic drugs, including methotrexate, sulfasalazine, gold, antimalarials, and penicillamine.
Topics: Age Factors; Antimalarials; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Digestive System; Gold; Humans; Liver; Methotrexate; Penicillamine; Sulfasalazine | 1994 |
POLAROGRAPHIC ANALYSIS OF PROTEINS, AMINO ACIDS, AND OTHER COMPOUNDS BY MEANS OF THE BRDI CKA REACTION.
Topics: Amino Acids; Aminobutyrates; Animals; Cattle; Cobalt; Cysteine; Cystine; gamma-Globulins; Penicillamine; Pepsin A; Polarography; Proteins; Research; Serum Albumin; Serum Albumin, Bovine; Sulfhydryl Compounds; Trypsin | 1963 |
[Drug induced nephrotic syndrome].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antirheumatic Agents; Cysteine; Humans; Nephrotic Syndrome; Organogold Compounds; Penicillamine | 2004 |
[Therapeutic management of systemic sclerosis].
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Cyclophosphamide; Cysteine; Epoprostenol; Humans; Hypertension, Pulmonary; Immunosuppressive Agents; Interferons; Lung Diseases, Interstitial; Orthotic Devices; Penicillamine; Peripheral Blood Stem Cell Transplantation; Physical Therapy Modalities; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Scleroderma, Systemic; Vasodilator Agents | 2006 |
[Drug-induced nephrotic syndrome].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antineoplastic Agents; Antirheumatic Agents; Bone Density Conservation Agents; Cysteine; Diphosphonates; Gold Compounds; Humans; Interferons; Lithium Compounds; Nephrotic Syndrome; Pamidronate; Penicillamine | 2007 |
[Effect of disease modifying anti-rheumatic drugs on radiographic progression in rheumatoid arthritis].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Cysteine; Disease Progression; Drug Therapy, Combination; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Methotrexate; Penicillamine; Radiography; Randomized Controlled Trials as Topic; Sulfasalazine; Tacrolimus | 2009 |
Drug-induced pemphigus: A systematic review of 170 patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Antirheumatic Agents; Captopril; Cysteine; Drug-Related Side Effects and Adverse Reactions; Humans; Pemphigus; Penicillamine | 2021 |
4 trial(s) available for penicillamine and cysteine
| Article | Year |
|---|---|
SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteine; Drug Eruptions; Elasticity; Female; Gold; Humans; Middle Aged; Penicillamine; Tensile Strength; Time Factors | 1986 |
Rheumatoid arthritis: supplemental L-cysteine in penicillamine treatment--a controlled study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Female; Humans; Male; Middle Aged; Penicillamine | 1985 |
The treatment of cystinuria with N-acetyl-D-penicillamine, a comparison with the results of D-penicillamine treatment.
Topics: Acylation; Adolescent; Adult; Child; Cysteine; Cystinuria; Desensitization, Immunologic; Drug Hypersensitivity; Edema; Female; Humans; Hypoproteinemia; Kidney Diseases; Male; Penicillamine; Prednisolone; Proteinuria; Serum Albumin; Urea; Urinary Calculi | 1971 |
A comparison between bucillamine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Middle Aged; Penicillamine | 1997 |
317 other study(ies) available for penicillamine and cysteine
| Article | Year |
|---|---|
2,5,5-Trimethylthiazolidine-4-carboxylic acid, a D(-)-penicillamine-directed pseudometabolite of ethanol. Detoxication mechanism for acetaldehyde.
Topics: Acetaldehyde; Acetylation; Animals; Ethanol; Inactivation, Metabolic; Male; Methods; Penicillamine; Radioisotope Dilution Technique; Rats; Stereoisomerism; Thiazoles | 1978 |
Equilibrium and kinetics studies of transnitrosation between S-nitrosothiols and thiols.
Topics: Kinetics; Mercaptoethanol; Nitrosation; Nitroso Compounds; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Thermodynamics | 2001 |
Letter: The reactions of hydrogens atoms in aqueous solutions: effect of pH on reactions with cysteine and penicillamine.
Topics: Cysteine; Hydrogen; Hydrogen-Ion Concentration; Penicillamine; Radiation-Protective Agents; Radiation-Sensitizing Agents; Solutions; Water | 1975 |
[Studies on D-penicillamine (1): Inhibitory effect of D-penicillamine on the heat-Cu++ induced denaturation of human gamma-globulin (author's transl)].
Topics: Animals; Benzenesulfonates; Cattle; Chelating Agents; Copper; Cysteine; gamma-Globulins; Gold; Hot Temperature; Humans; Maleimides; Mercaptopurine; Penicillamine; Protein Binding; Protein Denaturation; Serum Albumin, Bovine; Thiomalates | 1978 |
Nephropathy induced by D-penicillamine.
Topics: Animals; Chemical Phenomena; Chemistry; Complement C1; Cysteine; Fluorescent Antibody Technique; Haplorhini; Humans; Immunoglobulin G; Kidney; Kidney Diseases; Kidney Glomerulus; Lymphocyte Activation; Macaca mulatta; Microscopy, Electron; Penicillamine; Proteinuria; Time Factors | 1978 |
The effect of chelation on the fate of intravenously administered cadmium in rats.
Topics: Animals; Cadmium; Chelating Agents; Cysteine; Digestive System; Dimercaprol; Edetic Acid; Female; Glutathione; Histidine; Injections, Intravenous; Kidney; Liver; Penicillamine; Rats | 1979 |
Low Dose D-penicillamine in cystinuria.
Topics: Adolescent; Adult; Cysteine; Female; Humans; Penicillamine; Proteinuria | 1977 |
Serum immunoglobulins in D-penicillamine-treated cystinurics.
Topics: Cysteine; Humans; Immunoglobulin G; Immunoglobulins; Penicillamine; Proteinuria | 1977 |
An outline of D-penicillamine metabolism.
Topics: Amino Acids; Biotransformation; Cysteine; Feces; Half-Life; Humans; Penicillamine | 1977 |
Effect of pH on the reactivity of the carbonate radical in aqueous solution.
Topics: Carbonates; Chymotrypsin; Cysteine; Histidine; Hydrogen-Ion Concentration; Methane; Methionine; Muramidase; Penicillamine; Photochemistry; Propionates; Ribonucleases; Solutions; Tyrosine; Water | 1975 |
Rat liver cysteine sulfinate decarboxylase: purification, new appraisal of the molecular weight and determination of catalytic properties.
Topics: Animals; Borohydrides; Carboxy-Lyases; Cysteine; Dithiothreitol; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Molecular Weight; Norepinephrine; Penicillamine; Protein Conformation; Pyridoxal Phosphate; Rats; Sulfhydryl Compounds; Sulfinic Acids; Temperature | 1975 |
Complexing of nickel(II) by cysteine, tyrosine, and related ligands and evidence for Zwitterion reactivity.
Topics: Binding Sites; Cysteine; Glutathione; Hydrogen-Ion Concentration; Kinetics; Ligands; Methionine; Methods; Nickel; Penicillamine; Tyrosine | 1975 |
Reactions of pyrzdoxal 5'-phosphate, 6-aminocaproic acid, cysteine, and penicilamine. Models for reactions of Schiff base linkages in pyridoxal 5'-phosphate-requiring enymes.
Topics: Aminocaproates; Anaerobiosis; Cysteine; Dithionitrobenzoic Acid; Hydrogen-Ion Concentration; Kinetics; Penicillamine; Pyridoxal Phosphate; Schiff Bases; Thiazoles | 1975 |
Oxidation of sulfhydryl groups to disulfides by sulfoxides.
Topics: Chemical Phenomena; Chemistry; Cysteine; Deuterium; Disulfides; Glutathione; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Penicillamine; Sulfhydryl Compounds; Sulfoxides; Valine | 1975 |
The inhibitory effect of D-penicillamine on human lymphocyte cultures stimulated by phytohaemagglutinin, the antagonistic action of L-cysteine and synergistic inhibition by copper sulphate.
Topics: Adult; Arthritis, Rheumatoid; Blood; Cells, Cultured; Copper; Culture Media; Cysteine; Drug Synergism; Humans; Lymphocyte Activation; Penicillamine; Phytohemagglutinins | 1979 |
Blood levels and side-effects of D-penicillamine.
Topics: Arthritis, Rheumatoid; Copper; Cysteine; Humans; Kinetics; Penicillamine | 1979 |
Studies on the influence of thiols on lymphocytes (T-type lymphocytes) functions.
Topics: Animals; Cysteine; Oxidation-Reduction; Penicillamine; Pyridoxal Phosphate; Rats; Structure-Activity Relationship; Sulfhydryl Compounds; T-Lymphocytes; Thymus Gland; Uridine | 1978 |
Oxidation of various substrates by host grown Mycobacteria leprae and M. lepraemurium.
Topics: Culture Media; Cysteine; Dithioerythritol; Mycobacterium leprae; Mycobacterium lepraemurium; Oxidation-Reduction; Oxygen Consumption; Penicillamine; Polysorbates; Succinates; Yeasts | 1977 |
Acid dissociation and metal complex formation constants of penicillamine, cysteine, and antiarthritic gold complexes at simulated biological conditions.
Topics: Acids; Chelating Agents; Chemical Phenomena; Chemistry; Cysteine; Gold; Organometallic Compounds; Penicillamine; Potentiometry | 1979 |
Chromosomal breakage in Crohn's disease: anticlastogenic effect of D-penicillamine and L-cysteine.
Topics: Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Colitis, Ulcerative; Crohn Disease; Culture Media; Cysteine; Humans; Lymphocytes; Penicillamine | 1979 |
Ion-exchange chromatography of sulfur amino acids on a single-column amino acid analyzer.
Topics: Amino Acids; Autoanalysis; Chromatography, Ion Exchange; Cysteine; Glutathione; Penicillamine; Taurine | 1979 |
Circular dichroism and resonance Raman spectra of the Cu(II)-Cu(I) complex of D-penicillamine. The CuS(CYs) stretching mode in blue copper proteins.
Topics: Circular Dichroism; Copper; Cysteine; Metalloproteins; Molecular Conformation; Penicillamine; Protein Conformation; Spectrum Analysis, Raman | 1979 |
Lowering of ethanol-derived circulating blood acetaldehyde in rats by D-penicillamine.
Topics: Acetaldehyde; Animals; Breath Tests; Cysteine; Cystine; Ethanol; Male; Penicillamine; Rats | 1977 |
Chemical and biological characterization of different Tc complexes of cysteine and cysteine derivatives.
Topics: Acetylcysteine; Animals; Cysteine; Isotope Labeling; Male; Penicillamine; Rats; Technetium; Tissue Distribution | 1978 |
Effects of heavy metal ions on the electrical properties of mucous epithelial cells in the newt stomach.
Topics: Animals; Cysteine; Electric Conductivity; Epithelial Cells; Epithelium; Gastric Mucosa; In Vitro Techniques; Membrane Potentials; Metals; Penicillamine; Salamandridae | 1978 |
Intrarenal modulation of the efficacy of mercurial diuretics.
Topics: Animals; Citrates; Cysteine; Diuresis; Dogs; Drug Synergism; Humans; Kidney; Organomercury Compounds; Penicillamine; Rats | 1977 |
The effect of oral doses of a polythiol resin on the excretion of methylmercury in mice treated with cysteine, D-penicillamine or phenobarbitone.
Topics: Animals; Cysteine; Feces; Kinetics; Male; Mercury; Methylmercury Compounds; Mice; Penicillamine; Phenobarbital; Resins, Plant; Sulfhydryl Compounds; Time Factors | 1976 |
The effect of D-penicillamine on polymorphonuclear leukocyte function.
Topics: Cysteine; Dose-Response Relationship, Drug; Glucuronidase; L-Lactate Dehydrogenase; Latex; Microspheres; Neutrophils; Penicillamine; Phagocytosis | 1976 |
Mechanism of the protective action of cysteine and penicillamine against acetaldehyde-induced mitochondrial injury.
Topics: Acetaldehyde; Acetylcysteine; Animals; Carbon Dioxide; Cysteine; In Vitro Techniques; Mitochondria, Liver; Oxygen Consumption; Penicillamine; Rats; Structure-Activity Relationship; Time Factors | 1976 |
Mobilization of methyl mercury in vivo and vitro using N-acetyl-DL-penicillamine and other complexing agents.
Topics: Animals; Brain Chemistry; Chelating Agents; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutathione; Homocysteine; Methylmercury Compounds; Mice; Penicillamine | 1976 |
Beta-cyanoalanine synthase: purification and characterization.
Topics: Amino Acids; Aminooxyacetic Acid; Carbon-Sulfur Lyases; Chromatography, Gel; Chromatography, Ion Exchange; Cyanides; Cycloserine; Cysteine; Electrophoresis, Polyacrylamide Gel; Isoelectric Focusing; Kinetics; Lyases; Molecular Weight; Penicillamine; Plants; Propionates; Pyridoxal Phosphate; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors | 1975 |
An extracorporeal complexing hemodialysis system for the treatment of methylmercury poisoning. I. In vitro studies of the effects of four complexing agents on the distribution and dialyzability of methylmercury in human blood.
Topics: Acetates; Acetylcysteine; Blood Proteins; Cysteine; Humans; In Vitro Techniques; Mercury Isotopes; Mercury Poisoning; Methylmercury Compounds; Penicillamine; Protein Binding; Radioisotopes; Renal Dialysis; Sulfhydryl Reagents; Time Factors | 1975 |
Proceedings: Antiarthritic properties of cystein derivatives in comparison with D-penicillamin in rats.
Topics: Animals; Arthritis, Rheumatoid; Cysteine; Elasticity; Female; Freund's Adjuvant; Penicillamine; Rats; Tendons | 1975 |
Diversion of ethanol metabolism by sulfhydryl amino acids. D-penicillamine-directed excretion of 2,5,5-trimethyl-D-thiazolidine-4-carboxylic acid in the urine of rats after ethanol administration.
Topics: Acetaldehyde; Animals; Cysteine; Ethanol; Male; Penicillamine; Rats; Thiazoles | 1975 |
Relative reactivities of sulfhydryl groups with N-acetyl dehydroalanine and N-acetyl dehydroalanine methyl ester.
Topics: Alanine; Chemical Phenomena; Chemistry; Cysteine; Esters; Magnetic Resonance Spectroscopy; Penicillamine; Sulfhydryl Compounds; Temperature; Time Factors | 1976 |
Characterization of gold in urine and bile following administration of gold sodium thiomalate with chelating agents to rats.
Topics: Animals; Bile; Chelating Agents; Chromatography; Cysteine; Electrophoresis; Gold; Gold Sodium Thiomalate; Injections, Intravenous; Male; Penicillamine; Rats; Rats, Inbred Strains; Succimer; Unithiol | 1992 |
Study of activated oxygen production by some thiols using chemiluminescence.
Topics: Cysteine; Glutathione; Kinetics; Lipid Peroxidation; Luminescent Measurements; Malondialdehyde; Oxidation-Reduction; Penicillamine; Succimer; Sulfhydryl Compounds; Superoxides; Unithiol | 1992 |
Interaction between endothelium-derived relaxing factors, S-nitrosothiols, and endothelin-1 on Ca2+ mobilization in rat vascular smooth muscle cells.
Topics: Animals; Calcium; Cells, Cultured; Cysteine; Drug Interactions; Endothelins; Glutathione; Muscle, Smooth, Vascular; Nitric Oxide; Nitroso Compounds; Penicillamine; Rats; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; S-Nitrosothiols | 1992 |
Protective effects of chelating agents against renal toxicity of gold sodium thiomalate in rats.
Topics: Animals; Chelating Agents; Cysteine; Glycosuria; Gold Sodium Thiomalate; Kidney Diseases; Male; Penicillamine; Rats; Rats, Inbred Strains; Succimer; Unithiol | 1991 |
Synergistic inhibition of aminopeptidase B by penicillamine or cysteine and metallic salts.
Topics: Aminopeptidases; Animals; Cysteine; Drug Synergism; In Vitro Techniques; L Cells; Metals; Mice; Penicillamine | 1991 |
Effect of bucillamine (SA96) on type II collagen induced arthritis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cell Division; Collagen; Cysteine; Dose-Response Relationship, Drug; Indomethacin; Male; Penicillamine; Rats; Synovial Membrane | 1991 |
The formation and structure of the sulfoxyl radicals RSO(.), RSOO(.), RSO2(.), and RSO2OO(.) from the reaction of cysteine, glutathione and penicillamine thiyl radicals with molecular oxygen.
Topics: Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Oxygen; Penicillamine; Sulfhydryl Compounds | 1990 |
Copper(II) (3,5-diisopropylsalicylate)2 oxidizes thiols to symmetrical disulfides and oxidatively converts mixtures of 5-thio-2-nitrobenzoic acid and nonsymmetrical 5-thio-2-nitrobenzoic acid disulfides to symmetrical disulfides.
Topics: Cysteine; Disulfides; Dithionitrobenzoic Acid; Drug Interactions; Glutathione; Nitrobenzoates; Oxidation-Reduction; Penicillamine; Salicylates; Sulfhydryl Compounds | 1991 |
Sulfur amino acid metabolism in cystinuria: a biochemical and clinical study of patients.
Topics: Acetylcysteine; Adult; Amino Acids, Sulfur; Cysteine; Cystinuria; Female; Homozygote; Humans; Male; Penicillamine; Tiopronin | 1990 |
Differences in the effects of the antirheumatic drugs, bucillamine and D-penicillamine, on mitogen-induced proliferation of mouse spleen cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalase; Cell Division; Cells, Cultured; Concanavalin A; Copper; Cysteine; Male; Mice; Mice, Inbred C3H; Penicillamine; Spleen; Structure-Activity Relationship | 1990 |
Mutagenicity experiments on L-cysteine and D-penicillamine using V79 cells as indicators and for metabolic activation.
Topics: Amino Acids, Sulfur; Animals; Cells, Cultured; Cysteine; Drug Resistance; Kidney; Male; Mitochondria; Mutagenicity Tests; Mutagens; Penicillamine; Rats; Rats, Inbred Strains; Salmonella typhimurium; Thioguanine | 1990 |
[Pharmacological studies on N-(2-mercapto-2-methylpropanoyl)-L-cysteine(SA96). IV. Effects of SA96 and its main metabolite, SA679, on denaturation of human gamma-globulin and adjuvant arthritis in rats].
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Cysteine; gamma-Globulins; Indomethacin; Male; Organ Size; Penicillamine; Protein Denaturation; Rats; Rats, Inbred Lew; Serum Albumin, Bovine | 1985 |
Attempt at therapy in sulphite oxidase deficiency.
Topics: Cysteine; Female; Humans; Infant, Newborn; Metabolism, Inborn Errors; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Penicillamine; Sulfites; Taurine | 1989 |
Effect of thiols on lipid peroxidation in rat liver microsomes.
Topics: Acetylcysteine; Animals; Cysteamine; Cysteine; Dithiothreitol; Glutathione; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; Penicillamine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Sulfhydryl Compounds | 1989 |
Effect of pH on mutagenesis by thiols in Salmonella typhimurium TA102.
Topics: Chemical Phenomena; Chemistry; Cysteine; Dipeptides; Glutathione; Hydrogen-Ion Concentration; Mutagenicity Tests; Mutagens; Penicillamine; Salmonella typhimurium; Sulfhydryl Compounds | 1989 |
Thallium (I) interactions in biological fluids: a potentiometric investigation of thallium(I) complex equilibria with some sulphur-containing amino acids.
Topics: Acetylcysteine; Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Kinetics; Penicillamine; Potentiometry; Thallium | 1989 |
Capacitation of hamster spermatozoa with the divalent cation chelators D-penicillamine, L-histidine, and L-cysteine in a protein-free culture medium.
Topics: Animals; Cations, Divalent; Chelating Agents; Cricetinae; Culture Media; Cysteine; Epididymis; Female; Fertilization in Vitro; Histidine; Male; Penicillamine; Sperm Capacitation; Zinc | 1989 |
Inhibition of the covalent binding reaction of complement component C4 by penicillamine, an anti-rheumatic agent.
Topics: Anaphylatoxins; Complement C4; Complement C4a; Complement C4b; Complement Pathway, Classical; Cysteine; Hemolysis; Humans; Penicillamine | 1989 |
An ESR investigation of the reactions of glutathione, cysteine and penicillamine thiyl radicals: competitive formation of RSO., R., RSSR-., and RSS(.).
Topics: Chemical Phenomena; Chemistry; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Nitrogen; Oxygen; Penicillamine; Sulfhydryl Compounds | 1988 |
Biochemical and clinical changes occurring during the treatment of rheumatoid arthritis with novel antirheumatoid drugs.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Viscosity; Captopril; Cysteine; Female; Humans; Male; Middle Aged; Penicillamine; Sulfasalazine; Sulfates; Zinc; Zinc Sulfate | 1985 |
Oxidation of thiol drugs and biochemicals by the lactoperoxidase/hydrogen peroxide system.
Topics: Acetylcysteine; Captopril; Cysteamine; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Hydrogen Peroxide; Lactoperoxidase; Oxygen Consumption; Penicillamine; Peroxidases; Sulfhydryl Compounds | 1987 |
D-penicillamine metabolism: in vitro studies of S-oxidation mechanisms.
Topics: Animals; Carbocysteine; Cysteine; Cytochrome P-450 Enzyme System; Cytosol; Female; Male; Microsomes, Liver; Oxidation-Reduction; Penicillamine; Rats; Sulfates | 1988 |
Application of high resolution 1H-NMR spectroscopy to the detection of penicillamine and its metabolites in human urine.
Topics: Cysteine; Humans; Magnetic Resonance Spectroscopy; Penicillamine | 1988 |
Thiol exchange reactions involving selenotrisulfides.
Topics: Chromatography, High Pressure Liquid; Cysteine; Glutathione; Penicillamine; Selenious Acid; Selenium; Sulfhydryl Compounds; Sulfides | 1988 |
Measurement of plasma thiols after derivatization with monobromobimane.
Topics: Bridged Bicyclo Compounds; Chromatography, High Pressure Liquid; Cysteine; Glutathione; Homocysteine; Humans; Penicillamine; Sulfhydryl Compounds; Ultrafiltration | 1988 |
Measurement of urinary cystine and cysteinyl-penicillamine in patients with cystinuria.
Topics: Amino Acids; Chromatography, Gas; Chromatography, High Pressure Liquid; Cysteine; Cystinuria; Electrochemistry; Humans; Penicillamine; Sulfhydryl Compounds | 1986 |
Cysteine analogues potentiate glucose-induced insulin release in vitro.
Topics: Acetylcysteine; Animals; Cysteamine; Cysteine; Dose-Response Relationship, Drug; Female; Glucose; Glutathione; Insulin; Insulin Secretion; Islets of Langerhans; Male; Penicillamine; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1986 |
Metabolization of 14C-N-acetylpenicillamine and 14C-cysteine in relation to 1-chloro-2,4-dinitrobenzene and sulphobromophtalein conjugation and biliary excretion in the rat.
Topics: Animals; Bile; Chromatography, Gel; Chromatography, Thin Layer; Cysteine; Dinitrochlorobenzene; Liver; Male; Penicillamine; Rats; Rats, Inbred Strains; Sulfobromophthalein | 1987 |
Beta-substituted cysteines as sequestering agents for ethanol-derived acetaldehyde in vivo.
Topics: Acetaldehyde; Animals; Chemical Phenomena; Chemistry; Cyanamide; Cysteine; Disulfiram; Ethanol; Male; Oxidation-Reduction; Penicillamine; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1987 |
The use of D-penicillamine in patients with rheumatoid arthritis undergoing hemodialysis.
Topics: Arthritis, Rheumatoid; Cysteine; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Penicillamine; Renal Dialysis; Time Factors | 1986 |
Effects of immunomodulators on candidacidal activity of normal peritoneal cells in BALB/c mice.
Topics: Animals; Anti-Inflammatory Agents; Candidiasis; Cysteine; Female; Hydrocortisone; Levamisole; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Penicillamine | 1986 |
Mechanism of N-acetylpenicillamine (NAPA) potentiation of biliary excretion of methyl mercury in the rat. Influence of glutathione depletors, and metabolization of NAPA and of cysteine in relation to 1-chloro-2,4-dinitrobenzene (DNB) and bromosulphophthal
Topics: Animals; Bile; Biological Transport; Cyclohexanes; Cyclohexenes; Cysteine; Dinitrochlorobenzene; Glutathione; Liver; Methylmercury Compounds; Penicillamine; Rats; Sulfobromophthalein | 1986 |
Mutagenicity of cysteine and penicillamine and its enantiomeric selectivity.
Topics: Animals; Cysteine; Kidney; Liver; Male; Mutagenicity Tests; Mutagens; Penicillamine; Rats; Rats, Inbred Strains; Salmonella typhimurium; Stereoisomerism | 1985 |
Mechanistic flexibility in the reduction of copper(II) complexes of aliphatic polyamines by mercapto amino acids.
Topics: Amino Acids, Sulfur; Chemical Phenomena; Chemistry; Copper; Cysteine; Glutathione; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Oxidation-Reduction; Penicillamine; Polyamines | 1985 |
In vitro production and scavenging of hydrogen peroxide by D-penicillamine. Relationship to copper availability.
Topics: Ceruloplasmin; Concanavalin A; Copper; Copper Sulfate; Cysteine; Humans; Hydrogen Peroxide; Lymphocyte Activation; Monocytes; Penicillamine; Time Factors | 1985 |
[Pharmacological studies of N-(2-mercapto-2-methylpropionyl)-L-cysteine (SA 96). VI. Effects on vitamin B6, metals and skin collagen in rats].
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Collagen; Cysteine; Liver; Male; Metals; Penicillamine; Pyridoxine; Rats; Rats, Inbred Strains; Skin | 1985 |
Aspects of formation of the D-penicillamine-antigenic determinant from penicilloyl compounds.
Topics: Antibody Specificity; Cysteine; Epitopes; Penicillamine; Penicillanic Acid; Peptides; Protein Binding | 1973 |
Inhibition of endotoxin-induced platelet agglutination, histamine and serotonin release in vitro by thiol-compounds.
Topics: Animals; Ascorbic Acid; beta-Aminoethyl Isothiourea; Blood Platelets; Cysteine; Endotoxins; Glutathione; Glycolates; Hemagglutination; Histamine Release; In Vitro Techniques; Mercaptoethanol; Penicillamine; Rabbits; Serotonin; Thioglycolates | 1964 |
Isolation of immunoglobulin A (IgA) from human colostrum.
Topics: Alkylation; Amino Acids; Aspartic Acid; Buffers; Chromatography, Gel; Colostrum; Cysteine; Electrophoresis; Female; gamma-Globulins; Glutamates; Humans; Immunoelectrophoresis; Penicillamine; Pregnancy; Ultracentrifugation | 1966 |
[Effect of different thiols on renal excretion of water and osmotically active substances in the rabbit].
Topics: Absorption; Alanine; Animals; beta-Aminoethyl Isothiourea; Cysteine; Dimercaprol; Kidney Concentrating Ability; Kidney Tubules; Osmolar Concentration; Penicillamine; Rabbits; Serine; Urine | 1968 |
[Effect of mercaptans on urine volume and osmolarity in rabbits].
Topics: Alanine; Animals; beta-Aminoethyl Isothiourea; Cysteine; Dimercaprol; Female; Kidney; Osmolar Concentration; Penicillamine; Rabbits; Receptors, Drug; Serine; Sodium Chloride; Thiosulfates; Urine; Vasopressins | 1969 |
[Inhibition of aerobic glycolysis in ascites tumor cells by thiazolidines of L-glyceraldehyde].
Topics: Air; Animals; Carcinoma, Ehrlich Tumor; Cysteine; Depression, Chemical; Glyceraldehyde; Glycolysis; Lactates; Mice; Penicillamine; Spectrophotometry; Stereoisomerism; Thiazoles | 1970 |
A mechanism for the action of penicillamine in the treatment of Wilson's disease.
Topics: Chelating Agents; Copper; Cysteine; Edetic Acid; Electron Spin Resonance Spectroscopy; Hepatolenticular Degeneration; Methods; Models, Biological; Nitrogen; Penicillamine; Sulfur; Thiosemicarbazones | 1969 |
[Satisfactory prophylaxis of urinary lithiasis with D-penicillamine in cystinuria].
Topics: Adult; Cysteine; Cystine; Cystinuria; Diet Therapy; Female; Humans; Penicillamine; Urinary Calculi | 1970 |
Collagenase inhibitors (penicillamine).
Topics: Adult; Alkalies; Animals; Arginine; Bacitracin; Burns, Chemical; Cicatrix; Contact Lenses, Hydrophilic; Cornea; Corneal Ulcer; Cystamine; Cysteine; Cystine; Edetic Acid; Eye Burns; Female; Fibroblasts; Glutathione; Humans; Leukocytes; Magnesium Sulfate; Male; Methods; Microbial Collagenase; Middle Aged; Penicillamine; Rabbits; Spectrophotometry, Atomic | 1973 |
Corneal collagenases: evidence for zinc metalloenzymes.
Topics: Animals; Calcium; Carbon Radioisotopes; Chemistry, Organic; Chromatography; Cornea; Corneal Ulcer; Culture Techniques; Cysteine; Edetic Acid; Humans; Indicators and Reagents; Metalloproteins; Microbial Collagenase; Organic Chemistry Phenomena; Penicillamine; Phenanthrolines; Quinolines; Rabbits; Zinc; Zinc Isotopes | 1973 |
Influences on the structural stability of collagen in relation to ageing.
Topics: Aging; Animals; Biomechanical Phenomena; Collagen; Connective Tissue; Cysteine; Drug Interactions; Formaldehyde; Methionine; Muscle Contraction; Penicillamine; Perchlorates; Rats; Sodium Chloride; Tail; Tendons | 1973 |
Effect of D-penicillamine on poliovirus replication in HeLa cells.
Topics: Antiviral Agents; Carbon Radioisotopes; Cysteine; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Penicillamine; Poliovirus; RNA, Viral; Sulfhydryl Compounds; Time Factors; Uridine; Viral Proteins; Virus Replication | 1974 |
Inhibition by homocysteine of serine dehydratase and other pyridoxal 5'-phosphate enzymes of the rat through cofactor blockage.
Topics: Alanine Transaminase; Animals; Cysteine; Homocysteine; Homocystinuria; Humans; L-Serine Dehydratase; Liver; Male; Norepinephrine; Penicillamine; Pyridoxal Phosphate; Rats; Spectrophotometry; Stereoisomerism; Tyrosine Transaminase | 1971 |
[Studies on the oxidation-reduction potentials of 2-mercaptopropionylglycine and penicillamine using thiol-disulfide exchange reactions with cysteine and glutathione (author's transl)].
Topics: Amino Acids, Sulfur; Cysteine; Disulfides; Glutathione; Glycine; Oxidation-Reduction; Penicillamine; Sulfhydryl Compounds | 1974 |
The curative effects of cysteamine, cysteine, and dithiocarb in experimental paracetamol poisoning.
Topics: Acetaminophen; Alcohols; Animals; Carboxylic Acids; Chemical and Drug Induced Liver Injury; Cysteamine; Cysteine; Dimercaprol; Enzymes; Flavonoids; Glutathione; Lethal Dose 50; Liver; Male; Mice; Penicillamine; Poisoning; Thiazoles; Thiocarbamates; Thioctic Acid | 1974 |
[Current treatment of hepatolenticular degenerescence].
Topics: Adrenal Cortex Hormones; Cysteine; Diet Therapy; Dimercaprol; Edetic Acid; Folic Acid; Hepatolenticular Degeneration; Humans; Penicillamine | 1972 |
[Experimental studies on the chemical dissolution of cystine stones].
Topics: Animals; Cysteamine; Cysteine; Cystine; Disulfides; Dithiothreitol; Glutathione; Glycine; Isomerism; Kidney Calculi; Lethal Dose 50; Mercaptopurine; Mice; Penicillamine; Rabbits; Rats; Solubility; Spectrophotometry, Infrared; Sulfhydryl Compounds; Water | 1972 |
New internal standards for basic amino acid analyses.
Topics: Amino Acids; Benzyl Compounds; Chemical Phenomena; Chemistry; Chromatography, Ion Exchange; Cysteine; Hydrogen-Ion Concentration; Methods; Nitro Compounds; Penicillamine; Pyridines; Styrenes; Time Factors; Vinyl Compounds | 1973 |
The role of sulfhydryl groups in three models of inflammatory disease.
Topics: Animals; Arthritis; Carrageenan; Croton Oil; Cyclophosphamide; Cysteine; Dexamethasone; Disulfides; Edema; Ethylmaleimide; Freund's Adjuvant; Glycoproteins; Granuloma; Indomethacin; Male; Penicillamine; Rats; Sulfhydryl Compounds | 1973 |
The reactions of hydrogen atoms in aqueous solutions: thiols.
Topics: Cysteamine; Cysteine; Hydrogen; Mercaptoethanol; Penicillamine; Propionates; Radiation-Protective Agents; Radiochemistry; Sulfhydryl Compounds | 1973 |
Hydrated electron reactions with thiols in acidic aqueous solutions.
Topics: Cysteamine; Cysteine; Hydrogen-Ion Concentration; Penicillamine; Radiation Effects; Solutions; Sulfhydryl Compounds; Water | 1973 |
Amino acids and inflammation.
Topics: Amino Acids; Animals; Carrageenan; Cysteine; Dextrans; Dose-Response Relationship, Drug; Esters; Freund's Adjuvant; Glycine; Hindlimb; Inflammation; Penicillamine; Phenylalanine; Rats | 1973 |
[The anti-hepatotoxic effect of aliphatic and heterocyclic mercapto compounds in CCl4-induced liver damage in the rat. I].
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cholinesterases; Cysteine; Homocysteine; Male; Penicillamine; Rats; Structure-Activity Relationship; Sulfhydryl Compounds | 1973 |
Simple polarographic determination of cystine in urine with cystinuria.
Topics: Amino Acids; Blood Proteins; Cobalt; Cysteine; Cystinuria; Evaluation Studies as Topic; Homocysteine; Humans; Manganese; Methods; Nickel; Oxidation-Reduction; Penicillamine; Polarography; Polyethylene Glycols; Sulfites; Time Factors; Zinc | 1973 |
[Studies on the formation of mixed disulfides between D-penicillamine and serum proteins (author's transl)].
Topics: Animals; Blood Proteins; Cysteine; Cystine; Disulfides; Ethylmaleimide; Male; Penicillamine; Protein Binding; Rats; Serum Albumin | 1973 |
Compartmental study on the pharmacokinetics of D-penicillamine.
Topics: Animals; Biological Transport; Blood Proteins; Cysteine; Diffusion; Disulfides; Injections, Intravenous; Kidney; Kinetics; Liver; Mathematics; Models, Biological; Muscles; Organ Specificity; Penicillamine; Protein Binding; Rats; Skin; Time Factors | 1973 |
[Malabsorption syndrome and intestinal pseudoobstruction in primary vascular and heart amyloidosis].
Topics: Adult; Amyloidosis; Antibody Formation; Antigen-Antibody Complex; Azathioprine; Chloramphenicol; Cysteine; Heart Diseases; Humans; Intestinal Obstruction; Malabsorption Syndromes; Male; Melphalan; Penicillamine; Prednisone; Time Factors; Vascular Diseases | 1973 |
Penicillamine treatment of cystinuria.
Topics: Adult; Autoanalysis; Ceruloplasmin; Chromatography, Ion Exchange; Copper; Cysteine; Cystinuria; Depression, Chemical; Female; Follow-Up Studies; Humans; Male; Middle Aged; Penicillamine; Time Factors; Zinc | 1974 |
Cystinosis: selective induction of vacuolation in fibroblasts by L-cysteine-D-penicillamine disulfide.
Topics: Biological Transport; Culture Techniques; Cysteine; Cystine; Cystinosis; Cytoplasm; Fibroblasts; Humans; Lysosomes; Microscopy, Phase-Contrast; Penicillamine; Sulfides | 1970 |
Inhibition of S-91 mouse melanoma metastases and growth by D-penicillamine.
Topics: Animals; Catechol Oxidase; Copper; Cysteine; Melanoma; Mice; Neoplasm Metastasis; Penicillamine; Tyrosine | 1969 |
Beta-substituted N-formyl-S-benzylcysteines.
Topics: Cysteine; Penicillamine | 1970 |
[Action of antibiotic substances from the garden tulip Tulipa gesneriana on bacteria].
Topics: Amino Acids; Anti-Bacterial Agents; Bacillus subtilis; Bacteriological Techniques; Chromatography, Paper; Cysteine; Glycosides; Hydroxybutyrates; Oxygen Consumption; Penicillamine; Plant Extracts; Plants | 1970 |
35Cl nuclear magnetic resonance studies of metal binding to bovine serum albumin.
Topics: Animals; Cadmium; Cattle; Chlorine; Copper; Cyanides; Cysteine; Dimercaprol; Edetic Acid; Hydrogen-Ion Concentration; Lead; Magnetic Resonance Spectroscopy; Manganese; Mercury; Metals; Methylation; Penicillamine; Propionates; Protein Binding; Radioisotopes; Serum Albumin, Bovine; Sodium Chloride; Sulfhydryl Compounds; Thallium; Zinc | 1971 |
In vitro and in vivo inactivation of reagins with mercaptans.
Topics: Acetylcysteine; Animals; Antigen-Antibody Complex; Cysteamine; Cysteine; Desensitization, Immunologic; Haplorhini; Humans; Immunoglobulin E; Macaca; Mercaptoethanol; Passive Cutaneous Anaphylaxis; Penicillamine; Rhinitis, Allergic, Seasonal; Sulfhydryl Compounds | 1971 |
Effects of thiols on sodium chloride preference and copper and zinc metabolism in the rat.
Topics: Anemia, Hypochromic; Animals; Body Weight; Copper; Cysteine; Food Preferences; Male; Organ Size; Penicillamine; Priapism; Rats; Sodium Chloride; Taste; Testicular Diseases; Zinc | 1972 |
Effects of inorganic, aryl, alkyl and other mercury compounds on the outgrowth of cells and fibers from dorsal root ganglia in tissue culture.
Topics: Animals; Binding Sites; Cells, Cultured; Chick Embryo; Cysteine; Dimercaprol; Ganglia; Mercury; Neurons; Organometallic Compounds; Penicillamine; Phosphatidylethanolamines; Sphingomyelins; Structure-Activity Relationship | 1972 |
[Dissociation behavior of cysteine and related SH-compounds. A 13 C-NMR spectroscopic study on pH dependence of charge distribution].
Topics: Amines; Butyrates; Carbon Isotopes; Chemical Phenomena; Chemistry; Cysteamine; Cysteine; Homocysteine; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Methylation; Penicillamine; Propionates; Sulfhydryl Compounds; Tritium; Valine | 1972 |
Specificity and some other properties of liver serine sulphhydrase: evidence for its identity with cystathionine -synthase.
Topics: Acetates; Alanine; Amino Acids; Animals; Catalysis; Chickens; Chlorine; Chromatography, Gel; Chromatography, Paper; Cycloserine; Cysteamine; Cysteine; Electrophoresis, Paper; Glycolates; Homocysteine; Hydro-Lyases; Hydroxylamines; Isoelectric Focusing; Kinetics; L-Serine Dehydratase; Liver; Mercaptoethanol; Nitriles; Penicillamine; Propionates; Pyridoxal Phosphate; Rats; Serine; Species Specificity; Sulfhydryl Compounds; Sulfides; Sulfuric Acids; Thioglycolates | 1971 |
Protection against x-irradiation by sulphydryl compounds. II. Studies on the relation between chemical structure and protective activity for tissue culture cells.
Topics: beta-Aminoethyl Isothiourea; Chemical Phenomena; Chemistry; Culture Techniques; Cysteamine; Cysteine; Glutathione; Homocysteine; Hydrogen-Ion Concentration; Oxygen; Penicillamine; Radiation-Protective Agents; Sulfhydryl Compounds; Temperature; Thioglycolates | 1967 |
Treatment of cystinosis with a diet poor in cystine and methionine.
Topics: Amino Acids; Body Height; Body Weight; Child; Child, Preschool; Cysteine; Cystine; Cystinosis; Cystinuria; Diet Therapy; Dwarfism; Ergocalciferols; Female; Humans; Ketoglutaric Acids; Male; Methionine; Pedigree; Penicillamine; Pyruvates; Renal Tubular Transport, Inborn Errors | 1970 |
[The effect of ionizing radiation on the interrelationship of collagen molecules in the fibrils].
Topics: Amino Acids; Animals; Autoanalysis; Collagen; Cystamine; Cysteine; Dialysis; Electrophoresis, Disc; Guinea Pigs; Hydrogen-Ion Concentration; Hydroxyproline; Mercaptoethanol; Oxygen; Penicillamine; Polymers; Radiation Effects; Rats; Solutions; Spectrophotometry; Time Factors | 1970 |
Dermal connective tissue permeability in rheumatoid arthritics.
Topics: Adult; Animals; Arthritis, Rheumatoid; Ascorbic Acid; Carbamates; Cell Membrane Permeability; Connective Tissue; Cysteine; Dye Dilution Technique; Ethanol; Humans; Hyaluronic Acid; Injections, Intradermal; Isotonic Solutions; Penicillamine; Prednisone; Rats; Skin; Sodium Salicylate; Thiourea | 1966 |
The radiosensitivity of Escherichia coli B cultures. 3. Pre- and post-irradiation effect of compounds of the cysteine and cysteamine type.
Topics: Cysteamine; Cysteine; Escherichia coli; Penicillamine; Radiation Effects; Radiation-Protective Agents | 1966 |
Quantitative determination of biologically important thiols and disulfides by gas-liquid chromatography.
Topics: Aldehydes; Chromatography, Gas; Cystamine; Cysteamine; Cysteine; Cystine; Homocysteine; Homocystine; Hot Temperature; Hydrogen-Ion Concentration; Lactones; Methionine; Methods; Penicillamine; Sulfhydryl Compounds; Sulfides | 1969 |
[Collagen synthesis inhibition by D-penicillamine in patients with chronic, aggressive hepatitis].
Topics: Chelating Agents; Chronic Disease; Collagen; Connective Tissue; Cysteine; Female; Hepatic Encephalopathy; Hepatitis; Humans; Middle Aged; Penicillamine; Prednisolone | 1969 |
On the mechanism of the in vitro production of Ham-positive red cells by sulphydryl compounds: role of pH and Free -SH groups.
Topics: beta-Aminoethyl Isothiourea; Blood Group Antigens; Cysteine; Erythrocytes; Glutathione Reductase; Hemolysis; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Mercaptoethanol; Mercaptoethylamines; Penicillamine; Propionates; Sulfhydryl Compounds | 1970 |
Studies on the treatment for methyl mercury poisoning "lowering of the methyl mercury content in the poisoned animal brain".
Topics: Animals; Brain Chemistry; Cysteine; Female; Liver; Mercury; Mercury Poisoning; Penicillamine; Protein Binding; Pyridoxine; Rats; Sulfhydryl Compounds | 1970 |
Transport of penicillamine across mucosa of the rat small intestine in vitro.
Topics: Alanine; Animals; Benzoates; Biological Transport; Chemical Phenomena; Chemistry; Chromatography; Cyanides; Cysteine; In Vitro Techniques; Indicators and Reagents; Intestinal Mucosa; Intestine, Small; Inulin; Male; Mathematics; Penicillamine; Potassium; Pyridoxine; Rats; Spectrophotometry; Stereoisomerism; Sulfhydryl Reagents; Sulfides; Sulfur Isotopes; Tetroses; Valine; Water | 1970 |
Effect of thiols in biological systems on protein sulfhydryl content.
Topics: Acetamides; Animals; Autoradiography; Blood Proteins; Cysteine; Erythrocytes; Ethylmaleimide; Glycine; Humans; Kidney; Liver; Lung; Mice; Muscles; Penicillamine; Polarography; Skin; Spleen; Sulfhydryl Compounds; Sulfhydryl Reagents; Sulfur Isotopes; Tetroses; Time Factors | 1970 |
Whole-body and renal clearance of 203 Hg-chlormerodrin. The effect of chelating agents on clearance.
Topics: Aged; Chelating Agents; Chlormerodrin; Cysteine; Glomerular Filtration Rate; Humans; Kidney; Male; Mercury Isotopes; Middle Aged; Penicillamine; Time Factors | 1970 |
[Amino acids which are able to antagonize the antipolio effect of guanidine and D-penicillamine. Common features of their genetic codes].
Topics: Amino Acids; Aminobutyrates; Cysteine; Ethionine; Genetic Code; Guanidines; Isoleucine; Leucine; Methionine; Penicillamine; Phenylalanine; Poliomyelitis; Valine | 1967 |
[A new percentage assay for L-cysteine, L-cysteine HCl D-penicillamine, D-penicillamine HCl and N-acetyl-D-penicillamine. A critical evaluation method of a number of assay methods].
Topics: Cysteine; Penicillamine | 1967 |
Cystinosis. Plasma cystine and cysteine concentrations and the effect of D-penicillamine and dietary treatment.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Blood Chemical Analysis; Cysteine; Cystine; Cystinosis; Cystinuria; Diet Therapy; Female; Humans; Infant; Male; Methionine; Nitrogen; Penicillamine; Pyruvates | 1968 |
The role of tris(hydroxymethyl)aminomethane and cysteine in the dissociation of tryptophanase.
Topics: Acrylic Resins; Bacillus; Centrifugation, Density Gradient; Chemical Phenomena; Chemistry, Physical; Chromatography, Gel; Cysteine; Hydrogen-Ion Concentration; Lyases; Penicillamine; Pyridoxal Phosphate; Tromethamine; Tryptophan | 1968 |
A hypothesis on the homocystinuric's response to pyridoxine.
Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Chemistry, Clinical; Cysteine; Homocystinuria; Humans; Intellectual Disability; Male; Penicillamine; Pyridoxine | 1968 |
Chemical and mechanical changes in the collagenous framework of skin induced by thiol compounds.
Topics: Aminopropionitrile; Animals; Biomechanical Phenomena; Collagen; Cysteamine; Cysteine; Hydrogen-Ion Concentration; Hydroxyproline; In Vitro Techniques; Male; Penicillamine; Rats; Skin; Tail | 1968 |
Ham-positive red cells induced in vitro by N-acetylcysteine or D-penicillamine.
Topics: Acetylcholinesterase; Acetylcysteine; beta-Aminoethyl Isothiourea; Cysteine; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Penicillamine | 1968 |
Stability constants of metal complexes of L-cysteine, D-penicillamine, N-acetyl-D-penicillamine and some biguanides. Determination of stoichiometric stability constants by an accurate method for pH measurement.
Topics: Biguanides; Cysteine; Drug Stability; Hydrogen-Ion Concentration; Penicillamine | 1968 |
Effects of oral cysteine, penicillamine and N-acetyl-penicillamine on adjuvant arthritis in rats.
Topics: Adjuvants, Immunologic; Animals; Arthritis; Cysteine; Male; Mycobacterium; Penicillamine; Pyridoxine; Rats | 1968 |
[New attempts at the reduction of cystinuria].
Topics: Amides; Animals; Chromatography; Cysteine; Cystinuria; Dogs; Electrophoresis; Glycine; Humans; Penicillamine; Propionates; Rats | 1968 |
[On photometric titration of thiazolidines with p-mercuribenzoate and its application to the enzymatic-photometric determination of penicillin].
Topics: Benzoates; Cysteine; Glyceraldehyde; Penicillamine; Penicillin G; Penicillinase; Photometry; Sodium Hydroxide; Thiazoles | 1968 |
[On the reactions of D- and L-penicillamine with some aldimines of pyridoxal phosphate].
Topics: Alanine Transaminase; Chemical Phenomena; Chemistry; Cysteine; Imines; Ketoglutaric Acids; Penicillamine; Pyridoxal Phosphate; Pyridoxine; Spectrophotometry; Stereoisomerism | 1968 |
Sulfur-containing amino acids. II. Chromatography of disulfides and trisulfides with an automatic analyzer.
Topics: Amino Acids; Autoanalysis; Chromatography, Ion Exchange; Cysteine; Methods; Penicillamine; Sulfides | 1968 |
The reaction between cyanide and the mixed disulphide of cysteine and penicillamine.
Topics: Chemical Phenomena; Chemistry; Cyanides; Cysteine; Penicillamine; Sulfides | 1968 |
Effects of SH-compounds on rheumatoid factors in rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Blood Protein Electrophoresis; Cysteine; Hemagglutination Tests; Humans; Injections; Joints; Penicillamine; Rabbits; Rheumatoid Factor; Serologic Tests; Sulfhydryl Compounds; Synovial Fluid; Ultracentrifugation; Viscosity | 1969 |
Effects of lysosomal collagenolytic enzymes, anti-inflammatory drugs and other substances on some properties of insoluble collagen.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cathepsins; Collagen; Copper; Cysteine; Hydroxyproline; In Vitro Techniques; Lathyrism; Liver; Lysosomes; Mucoproteins; Penicillamine; Phenylacetates; Phenylbutazone; Rats; Solubility | 1969 |
Separation of cystine, penicillamine disulfide and cysteine-penicillamine mixed disulfide by automatic amino acid analysis.
Topics: Autoanalysis; Blood Chemical Analysis; Chemistry, Clinical; Chromatography, Ion Exchange; Cysteine; Cystine; Cystinuria; Humans; In Vitro Techniques; Penicillamine; Sulfides; Urine | 1966 |
Penicillamine and wound healing in young guinea pigs.
Topics: Animals; Collagen; Cysteine; Guinea Pigs; Milk; Penicillamine; Wound Healing | 1967 |
Excretion of trace elements in two penicillamine-treated cases of cystinuria.
Topics: Activation Analysis; Adult; Amino Acids; Calcium; Chromatography, Paper; Cysteine; Cystinuria; Female; Humans; Male; Middle Aged; Penicillamine; Phosphorus; Potassium; Sodium; Trace Elements | 1967 |
The determination of the acid dissociation constants of L-cysteine, D-penicillamine, N-acetyl-D-penicillamine and some biguanides by an accurate method for pH measurement.
Topics: Biguanides; Chemistry Techniques, Analytical; Cysteine; Hydrogen-Ion Concentration; Penicillamine | 1967 |
Stimulation and inhibition of thyroid iodinating enzyme systems.
Topics: Aminopterin; Animals; Cattle; Cysteine; Folic Acid; Fumarates; Hydrogen Peroxide; Hydrogen-Ion Concentration; In Vitro Techniques; Iodine; Iodine Isotopes; Microsomes; Mitochondria; Penicillamine; Peroxidases; Phenanthrolines; Thyroid Gland | 1967 |
Reactions of adrenochrome with some thiols.
Topics: Adrenochrome; Chemical Phenomena; Chemistry; Chromatography, Paper; Cysteine; Dimercaprol; Penicillamine; Spectrophotometry; Sulfhydryl Compounds; Ultraviolet Rays | 1967 |
The acid strength of the sulfhydryl and ammonium groups in L-cysteine and D-penicillamine; the determination of the micro acid stability constants.
Topics: Cysteine; Drug Stability; Penicillamine; Quaternary Ammonium Compounds; Sulfhydryl Compounds | 1967 |
Selenium--glutathione peroxidase: properties and synthesis.
Topics: Amino Acid Sequence; Animals; Aurothioglucose; Cysteine; Glutathione Peroxidase; Gold; Humans; Kinetics; Liver; Penicillamine; Protein Biosynthesis; RNA, Transfer, Amino Acyl; Selenious Acid; Selenium; Selenocysteine | 1984 |
Mobilization and removal of methylmercury in the dog during extracorporeal complexing hemodialysis with 2,3-dimercaptosuccinic acid (DMSA).
Topics: Animals; Cysteine; Dogs; Extracorporeal Circulation; Half-Life; Kinetics; Methylmercury Compounds; Penicillamine; Renal Dialysis; Succimer; Sulfhydryl Compounds; Time Factors | 1982 |
D-Penicillamine induced toxicity in rheumatoid arthritis: the role of sulphoxidation status and HLA-DR3.
Topics: Adult; Aged; Arthritis, Rheumatoid; Biotransformation; Carbocysteine; Cysteine; Female; Histocompatibility Antigens Class II; HLA-DR3 Antigen; HLA-DR4 Antigen; Humans; Male; Middle Aged; Penicillamine; Risk | 1984 |
[Effect of cysteine ethylester hydrochloride (Cystanin) on host defense mechanism].
Topics: Adjuvants, Immunologic; Animals; Cysteine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hemolytic Plaque Technique; Humans; Immunity; Infections; Leukocytes; Male; Mice; Mice, Inbred BALB C; Penicillamine; Phagocytosis; Rats; Rats, Inbred Strains | 1983 |
Immunopharmacologic studies of D-penicillamine-L-cysteine disulfide.
Topics: Animals; Arthritis, Experimental; Concanavalin A; Cysteine; Female; Hemolytic Plaque Technique; Hypersensitivity, Delayed; Immunity; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred Strains; Penicillamine; Rats; Rats, Inbred Strains | 1983 |
Drug protein conjugates--VI. Role of glutathione in the metabolism of captopril and captopril plasma protein conjugates.
Topics: Acetaminophen; Alanine Transaminase; Animals; Ascorbic Acid; Blood Proteins; Captopril; Cysteine; Glutathione; Liver; Male; Mice; Mice, Inbred CBA; Penicillamine; Proline; Protein Binding; Rats; Rats, Inbred Strains | 1983 |
Radical reactions in aqueous disulphide-thiol systems.
Topics: Cysteamine; Cysteine; Disulfides; Oxidation-Reduction; Penicillamine; Pulse Radiolysis; Sulfhydryl Compounds; Thioctic Acid | 1984 |
Regeneration of a functionally active rat brain muscarinic receptor by D-penicillamine after inhibition with methylmercury and mercuric chloride.
Topics: Animals; Brain; Cysteine; In Vitro Techniques; Male; Mercuric Chloride; Mercury; Methylmercury Compounds; Penicillamine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Muscarinic; Sulfhydryl Compounds; Synaptosomes | 1981 |
Studies on the metabolism of D-penicillamine and its interaction with probenecid in cystinuria and rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cysteine; Cystinuria; Drug Therapy, Combination; Female; Humans; Male; Penicillamine; Pilot Projects; Probenecid; Time Factors | 1984 |
Genetic aspects of the polymodally distributed sulphoxidation of S-carboxymethyl-L-cysteine in man.
Topics: Adolescent; Adult; Carbocysteine; Contraceptives, Oral; Cysteine; Female; Humans; Individuality; Male; Penicillamine; Polymorphism, Genetic; Sulfoxides | 1984 |
N-acetylpenicillamine potentiated excretion of methyl mercury in rat bile: influence of S-methylcysteine.
Topics: Animals; Bile; Bile Ducts; Chromatography, Gel; Cysteine; Drug Synergism; Glutathione; Injections, Intravenous; Liver; Male; Mercury Isotopes; Methylmercury Compounds; Penicillamine; Rats; Rats, Inbred Strains | 1984 |
D-penicillamine in patients with rheumatoid arthritis. Serum levels, pharmacokinetic aspects, and correlation with clinical course and side effects.
Topics: Arthritis, Rheumatoid; Cysteine; Drug Administration Schedule; Humans; Intestinal Absorption; Kinetics; Penicillamine; Time Factors | 1984 |
The mechanism of biliary excretion of methyl mercury: studies with methylthiols.
Topics: Animals; Bile; Cysteine; Hydrocarbons, Iodinated; Male; Methylmercury Compounds; Penicillamine; Rats; Rats, Inbred Strains; Time Factors; Tiopronin | 1983 |
Pharmacokinetics of the major metabolites of D-penicillamine in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Biotransformation; Chromatography, High Pressure Liquid; Cysteine; Dose-Response Relationship, Drug; Female; Humans; Metabolic Clearance Rate; Middle Aged; Penicillamine | 1984 |
The influence of some thiols on biliary excretion of methyl mercury.
Topics: Animals; Bile; Cysteine; Male; Mercury; Mercury Radioisotopes; Methylmercury Compounds; Penicillamine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Time Factors; Tiopronin | 1983 |
Biliary transport of glutathione and methylmercury.
Topics: Animals; Bile; Cysteine; Female; Glutathione; Male; Methylmercury Compounds; Penicillamine; Phenobarbital; Rats; Rats, Inbred Strains; Sulfhydryl Compounds | 1983 |
Metal ion complexing with D-penicillamine, L-cysteine and other biologically important thiol compounds.
Topics: Chemical Phenomena; Chemistry; Copper; Cysteine; Metals; Penicillamine; Peptides; Sulfhydryl Compounds | 1981 |
[Cystinuria therapy by ascorbic acid (author's transl)].
Topics: Ascorbic Acid; Cysteine; Cystine; Cystinuria; Humans; Intestinal Absorption; Kidney; Penicillamine; Tiopronin | 1982 |
[Determination of D-penicillamine and its metabolites in blood and urine].
Topics: Animals; Chromatography, High Pressure Liquid; Cysteine; Dogs; Humans; Male; Penicillamine; Rats; Rats, Inbred Strains; Time Factors | 1982 |
[The effect of sulfur compounds (N-acetylhomocysteine-thiolactone and penicillamine) on liver collagen metabolism in chronic thioacetamide poisoning].
Topics: Acetamides; Animals; Collagen; Cysteine; Hydroxyproline; Liver; Penicillamine; Rats; Thioacetamide; Thiophenes | 1980 |
SA96: an immunopharmacological profile in vitro.
Topics: Animals; Antibody Formation; Antibody-Producing Cells; Cattle; Concanavalin A; Cysteine; Dose-Response Relationship, Drug; Female; Fetal Blood; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Mice; Mice, Inbred BALB C; Penicillamine; Spleen | 1982 |
Chemical debridement of burns: mercaptans.
Topics: Acetylcysteine; Animals; Bromelains; Burns; Cysteine; Debridement; Drug Evaluation, Preclinical; Humans; Male; Mercaptoethanol; Penicillamine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Swine | 1981 |
Effects of thiol agents on the accumulation of cadmium by rat liver parenchymal and Kupffer cells.
Topics: Animals; Cadmium; Cysteine; Dimercaprol; Dithiothreitol; Kupffer Cells; Liver; Male; Penicillamine; Rats; Sulfhydryl Reagents; Tissue Distribution | 1981 |
Nitric oxide mediates penile erection in cats.
Topics: Acetylcholine; Animals; Arginine; Cats; Cysteine; Dose-Response Relationship, Drug; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Penicillamine; Penile Erection; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Substance P; Vasodilator Agents | 1994 |
Nitrovasodilator-induced relaxation and tolerance development in porcine vena cordis magna: dependence on intact endothelium.
Topics: Animals; Arginine; Cysteine; Dinoprost; Drug Tolerance; Endothelium, Vascular; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitrates; Nitroglycerin; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Substance P; Swine; Vasodilator Agents | 1994 |
Inhibition of viral replication by nitric oxide and its reversal by ferrous sulfate and tricarboxylic acid cycle metabolites.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Cell Line; Cells, Cultured; Chlorocebus aethiops; Citric Acid Cycle; Cysteine; DNA Replication; DNA, Viral; Epithelium; Female; Ferrous Compounds; Fibroblasts; Herpesvirus 1, Human; Humans; Kidney; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Nitric Oxide; Nitric Oxide Synthase; Penicillamine; Peptide Fragments; S-Nitroso-N-Acetylpenicillamine; Tricarboxylic Acids; Vaccinia virus; Vasodilator Agents; Virus Replication | 1995 |
Modulation of calcium-activated non-selective cation channel activity by nitric oxide in rat brown adipose tissue.
Topics: Adipose Tissue; Alkylation; Animals; Calcium; Cysteine; Depression, Chemical; In Vitro Techniques; Ion Channels; Male; Nitric Oxide; Nitroglycerin; Nitroprusside; Oxidation-Reduction; Patch-Clamp Techniques; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Sulfhydryl Compounds | 1995 |
Exogenous nitric oxide elicits chemotaxis of neutrophils in vitro.
Topics: Aminoquinolines; Cells, Cultured; Chemotactic Factors; Chemotaxis, Leukocyte; Cysteine; Enzyme Inhibitors; Guanylate Cyclase; Humans; Molsidomine; Neutrophils; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols | 1995 |
Effects of D-penicillamine on multiple immunogenic epitopes of the acetylcholine receptor.
Topics: Animals; Antibodies, Monoclonal; Antigen-Antibody Reactions; Cysteine; Epitopes; In Vitro Techniques; Iodoacetamide; Penicillamine; Receptors, Nicotinic; Torpedo | 1993 |
Stimulation of elemental mercury oxidation by SH compounds.
Topics: Acetates; Acetic Acid; Buffers; Cysteine; Fresh Water; Glutathione; Hydrochloric Acid; Hydrogen-Ion Concentration; Mercury; Oxidation-Reduction; Penicillamine; Sulfhydryl Compounds; Sulfuric Acids; Water Pollutants, Chemical | 1995 |
Reactions of copper(II)-oligopeptide complexes with hydrogen peroxide: effects of biological reductants.
Topics: Amino Acid Sequence; Antioxidants; Ascorbic Acid; Copper; Cysteamine; Cysteine; DNA Damage; Electron Spin Resonance Spectroscopy; Glutathione; Hydrogen Peroxide; Hydroxyl Radical; Kinetics; Molecular Sequence Data; Oligopeptides; Oxidation-Reduction; Penicillamine | 1995 |
Comparative effects of exogenous nitrovasodilators on cGMP levels in different canine blood vessels.
Topics: Animals; Arteries; Cyclic GMP; Cysteine; Dogs; In Vitro Techniques; Kinetics; Muscle, Smooth, Vascular; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Vasodilator Agents | 1995 |
Smooth muscle relaxing effects of NO, nitrosothiols and a nerve-induced relaxing factor released in guinea-pig colon.
Topics: Animals; Colon; Cysteine; Electric Stimulation; Female; Guinea Pigs; Half-Life; Hydroxylamine; Hydroxylamines; In Vitro Techniques; Iron; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitrogen Oxides; Nitroglycerin; Nitroso Compounds; Penicillamine; Rabbits; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Vasodilator Agents | 1994 |
ESR spin trapping investigation on peroxynitrite decomposition: no evidence for hydroxyl radical production.
Topics: Ascorbic Acid; Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Formates; Free Radicals; Glutathione; Hydroxyl Radical; Nitrates; Penicillamine; Spin Labels | 1994 |
Comparative inhibitory effects of bucillamine and D-penicillamine on the function of human B cells and T cells.
Topics: Adult; B-Lymphocytes; Cysteine; Humans; Immunoglobulin M; Interferon-gamma; Interleukin-6; Penicillamine; T-Lymphocytes | 1994 |
Influence of S-nitrosothiols and nitrate tolerance in the rat gastric fundus.
Topics: Aminoquinolines; Animals; Cyclic GMP; Cysteine; Drug Tolerance; Electric Stimulation; Female; Gastric Fundus; Glutathione; In Vitro Techniques; Male; Nitric Oxide; Nitroglycerin; Nitroso Compounds; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; S-Nitrosothiols | 1994 |
Chromate-mediated free radical generation from cysteine, penicillamine, hydrogen peroxide, and lipid hydroperoxides.
Topics: Chromates; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Hydrogen Peroxide; Hydroxyl Radical; Lipid Peroxides; Penicillamine | 1994 |
Kinetics and equilibria of S-nitrosothiol-thiol exchange between glutathione, cysteine, penicillamines and serum albumin.
Topics: Cysteine; Glutathione; Humans; Kinetics; Nitroso Compounds; Penicillamine; S-Nitrosoglutathione; Serum Albumin; Time Factors | 1994 |
Inhibition of mitogen-induced response of human peripheral blood mononuclear cells by bucillamine, a new antirheumatic sulfhydryl drug.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Copper; Copper Sulfate; Cysteine; DNA; Humans; Hydrogen Peroxide; Leukocytes, Mononuclear; Mitogens; Penicillamine; Phytohemagglutinins | 1994 |
Nuclear magnetic resonance studies of the binding of captopril and penicillamine by serum albumin.
Topics: Binding, Competitive; Captopril; Cysteine; Disulfides; Humans; Lactates; Magnetic Resonance Spectroscopy; Penicillamine; Protein Binding; Serum Albumin; Serum Albumin, Bovine; Sulfhydryl Compounds | 1993 |
Control of peptide disulfide regioisomer formation by mixed cysteine-penicillamine bridges. Application to endothelin-1.
Topics: Amino Acid Sequence; Animals; Chromatography, High Pressure Liquid; Cysteine; Disulfides; Endothelins; Isomerism; Mass Spectrometry; Molecular Sequence Data; Oxidation-Reduction; Penicillamine; Peptides; Rabbits; Rats | 1993 |
Differential effects of hydroxocobalamin on relaxations induced by nitrosothiols in rat aorta and anococcygeus muscle.
Topics: Animals; Aorta, Thoracic; Coenzyme A; Cysteine; Glutathione; Hemoglobins; Hydroxocobalamin; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Nitroso Compounds; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; S-Nitrosothiols; Vasodilator Agents | 1993 |
[Analysis of the state of patients with rheumatoid arthritis using a personal computer].
Topics: Age Factors; Arthritis, Rheumatoid; Cysteine; Databases, Factual; Female; Gold Sodium Thiomalate; Humans; Male; Microcomputers; Middle Aged; Penicillamine; Quality of Life; Time Factors | 1993 |
The long-term use of D-penicillamine for treating rheumatoid arthritis: is continuous therapy necessary?
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Clinical Protocols; Cysteine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Patient Compliance; Penicillamine; Time Factors | 1993 |
Generation of free radicals in reactions of Ni(II)-thiol complexes with molecular oxygen and model lipid hydroperoxides.
Topics: Acetylcysteine; Benzene Derivatives; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Histidine; Lipid Peroxides; Nickel; Oxygen; Penicillamine; Peroxides; Sulfhydryl Compounds; tert-Butylhydroperoxide | 1993 |
Regulation of B cell function by bucillamine, a novel disease-modifying antirheumatic drug.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; B-Lymphocytes; Copper; Cysteine; Depression, Chemical; Humans; Immunoglobulin M; Lymphocyte Activation; Penicillamine | 1993 |
Determination of thiol-containing drugs by chemiluminescence-flow injection analysis.
Topics: Acetylcysteine; Catalysis; Copper; Cysteine; Flow Injection Analysis; Hydrogen Peroxide; Hydrogen-Ion Concentration; Luminescent Measurements; Luminol; Penicillamine; Sulfhydryl Compounds; Tiopronin | 1993 |
Regulation of calcium-activated potassium channels by S-nitrosothiol compounds and cyclic guanosine monophosphate in rabbit coronary artery myocytes.
Topics: Animals; Calcium; Coronary Vessels; Cyclic GMP; Cysteine; In Vitro Techniques; Muscle, Smooth, Vascular; Penicillamine; Potassium Channels; Rabbits; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Vasodilator Agents | 1995 |
Piggy-back race.
Topics: Acetylcysteine; Animals; Binding, Competitive; Brain; Capillaries; Cells, Cultured; Cysteine; Endothelium, Vascular; Glutathione; Homocysteine; Leucine; Methylmercury Compounds; Penicillamine; Stereoisomerism; Sulfhydryl Compounds | 1995 |
Chemical mechanisms underlying the vasodilator and platelet anti-aggregating properties of S-nitroso-N-acetyl-DL-penicillamine and S-nitrosoglutathione.
Topics: Animals; Cysteine; gamma-Glutamyltransferase; Glutathione; In Vitro Techniques; Molecular Structure; Nitrogen Oxides; Nitroso Compounds; Penicillamine; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; S-Nitrosoglutathione; S-Nitrosothiols; Vasodilator Agents | 1995 |
Determination and metabolism of dithiol chelating agents. XVII. In humans, sodium 2,3-dimercapto-1-propanesulfonate is bound to plasma albumin via mixed disulfide formation and is found in the urine as cyclic polymeric disulfides.
Topics: Adult; Captopril; Chelating Agents; Chromatography, Thin Layer; Cysteine; Disulfides; Dithiothreitol; Humans; Male; Penicillamine; Protein Binding; Serum Albumin; Unithiol | 1996 |
Effect of superoxide dismutase mimics on radical adduct formation during the reaction between peroxynitrite and thiols--an ESR-spin trapping study.
Topics: Cyclic N-Oxides; Cysteine; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Free Radicals; Glutathione; Glutathione Disulfide; Kinetics; Nitrates; Organometallic Compounds; Oxygen; Penicillamine; Spin Labels; Sulfhydryl Compounds; Sulfites; Superoxide Dismutase; Superoxides | 1996 |
Exogenous nitric oxide causes collapse of retinal ganglion cell axonal growth cones in vitro.
Topics: Animals; Axons; Cells, Cultured; Cysteine; Free Radical Scavengers; Mercaptoethanol; Molsidomine; Neurites; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Nitroso Compounds; Penicillamine; Retinal Ganglion Cells; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Signal Transduction; Sulfhydryl Reagents; Time Factors; Vasodilator Agents; Xenopus laevis | 1996 |
Catecholamines enhance dihydrolipoamide dehydrogenase inactivation by the copper Fenton system. Enzyme protection by copper chelators.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Binding Sites; Captopril; Catecholamines; Catechols; Cattle; Chelating Agents; Copper; Cysteine; Dihydrolipoamide Dehydrogenase; Dopamine; Epinephrine; Hydrogen Peroxide; Hydroxyl Radical; Iron; Kinetics; Mammals; Norepinephrine; Oxidation-Reduction; Oxidopamine; Penicillamine | 1996 |
D-penicillamine causes free radical-dependent inactivation of activator protein-1 DNA binding.
Topics: Breast Neoplasms; Cell Nucleus; Cysteine; DNA, Neoplasm; Female; Free Radicals; Humans; Hydrogen Peroxide; Iron; Kinetics; Nuclear Proteins; Penicillamine; Polydeoxyribonucleotides; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Transcription Factor AP-1; Tumor Cells, Cultured | 1996 |
Nitric oxide inhibits aromatase activity: mechanisms of action.
Topics: Androstenedione; Aromatase Inhibitors; Carbon Monoxide; Cells, Cultured; Cysteine; Enzyme Inhibitors; Ethylmaleimide; Female; Gene Expression Regulation, Enzymologic; Granulosa Cells; Humans; Luteal Cells; Mercaptoethanol; Microsomes; NADP; Nitric Oxide; Penicillamine; Placenta; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Reagents | 1996 |
NO donors stimulate noradrenaline release from rat hippocampus in a calmodulin-dependent manner in the presence of L-cysteine.
Topics: Animals; Calmodulin; Cyclic GMP; Cysteine; Enzyme Inhibitors; Glutathione; Hippocampus; In Vitro Techniques; Male; Nitric Oxide; Norepinephrine; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Stereoisomerism; Sulfhydryl Compounds | 1996 |
Separation of urinary thiols as tributyltinmercaptides and determination using capillary isotachophoresis.
Topics: Antidotes; Cysteine; Disulfides; Electrophoresis; Electrophoresis, Capillary; Homocysteine; Humans; Hydrogen-Ion Concentration; Hydrolysis; Indicators and Reagents; Penicillamine; Sulfhydryl Compounds; Trialkyltin Compounds | 1996 |
Role of glutathione modulation in acrylonitrile-induced gastric DNA damage in rats.
Topics: Acrylonitrile; Animals; Cysteine; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Gastric Mucosa; Glutathione; Male; Maleates; Penicillamine; Proadifen; Rats; Rats, Sprague-Dawley; Stomach; Time Factors | 1996 |
Effect of bucillamine on the rat trinitrobenzene sulfonic acid induced model of colitis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cysteine; Male; Penicillamine; Rats; Rats, Wistar; Trinitrobenzenes | 1996 |
Cytoskeletal breakdown and apoptosis elicited by NO donors in cerebellar granule cells require NMDA receptor activation.
Topics: Animals; Apoptosis; Astrocytes; Calcium; Cells, Cultured; Cerebellum; Cysteine; Cytoskeleton; Dizocilpine Maleate; DNA Fragmentation; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Nitric Oxide; Penicillamine; Potassium; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Signal Transduction; Tyrosine | 1996 |
A novel approach to reduce the unwanted gastric side-effects of orally administered non-steroidal anti-inflammatory drugs in rats.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cysteine; Drug Therapy, Combination; Epoprostenol; Female; Gastric Mucosa; Gastrointestinal Diseases; Glutathione; Indomethacin; Penicillamine; Piroxicam; Rats; Rats, Wistar | 1997 |
Amperometric detection of organic thiols at a tungsten wire electrode following their separation by liquid chromatography.
Topics: Chromatography, Liquid; Cysteine; Electrochemistry; Electrodes; Glutathione; Homocysteine; Humans; Penicillamine; Seawater; Sensitivity and Specificity; Sulfhydryl Compounds; Thiourea; Tungsten | 1997 |
S-nitrosylation regulates apoptosis.
Topics: Apoptosis; Caspase 3; Caspases; Cysteine; Cysteine Endopeptidases; fas Receptor; GTP Phosphohydrolases; GTP-Binding Proteins; Humans; Jurkat Cells; Necrosis; Nitric Oxide; Penicillamine; Poly(ADP-ribose) Polymerases; Protein Glutamine gamma Glutamyltransferase 2; S-Nitroso-N-Acetylpenicillamine; Transglutaminases; Tumor Cells, Cultured | 1997 |
Disrupted [Ca2+]i homeostasis contributes to the toxicity of nitric oxide in cultured hippocampal neurons.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Analysis of Variance; Animals; Benzamides; Calcium; Cells, Cultured; Cysteine; Cysteine Proteinase Inhibitors; Dipeptides; Embryo, Mammalian; Enzyme Inhibitors; Free Radical Scavengers; Hemoglobins; Hippocampus; Homeostasis; Molsidomine; Neurons; Nitric Oxide; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Superoxide Dismutase | 1997 |
Nitric oxide does not modulate kainate receptor binding in human brain.
Topics: Brain; Cysteine; Female; Humans; Male; Middle Aged; Molsidomine; Nitric Oxide; Penicillamine; Receptors, Kainic Acid; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols | 1997 |
Complexation of copper(I) by thioamino acids. Implications for copper speciation in blood plasma.
Topics: Computer Simulation; Copper; Cysteine; Databases, Factual; Glutathione; Humans; Hydrogen-Ion Concentration; Ligands; Models, Biological; Oxidation-Reduction; Penicillamine; Thioamides | 1997 |
Nitric oxide donation and nitrite assays in the presence of thiols and albumin as determined by Griess' and Werringloer's methods.
Topics: Amino Acids; Cysteine; Glutathione; Molsidomine; Nitric Oxide; Nitrites; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Serum Albumin, Bovine; Sodium Nitrite; Sulfhydryl Compounds | 1997 |
Thiols protect the inhibition of myocardial aconitase by peroxynitrite.
Topics: Aconitate Hydratase; Animals; Citrates; Cysteine; Dose-Response Relationship, Drug; Drug Interactions; Ferrous Compounds; Glutathione; Glycine; Male; Myocardium; Nitrates; Penicillamine; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Compounds | 1998 |
Peroxynitrite-mediated vasorelaxation: evidence against the formation of circulating S-nitrosothiols.
Topics: Animals; Blood Flow Velocity; Cysteine; Glutathione; Hemodynamics; Male; Mercaptoethanol; Nitrates; Nitroso Compounds; Penicillamine; Rats; Rats, Sprague-Dawley; Regional Blood Flow; S-Nitrosoglutathione; S-Nitrosothiols; Serum Albumin, Bovine; Vasodilation | 1998 |
Pharmacological effects of SA96 (bucillamine) and its metabolites as immunomodulating drugs--the disulfide structure of SA-96 metabolites plays a critical role in the pharmacological action of the drug.
Topics: Adjuvants, Immunologic; Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cells, Cultured; Cysteine; Disulfides; Female; Gas Chromatography-Mass Spectrometry; Humans; Interleukin-6; Interleukin-8; Male; Middle Aged; Penicillamine; Rats; Structure-Activity Relationship; Synovial Fluid | 1998 |
Effects of nitric oxide on the eosinophil survival in vitro. A role for nitrosyl-heme.
Topics: Apoptosis; Cell Survival; Cysteine; Cytokines; Eosinophils; Guanylate Cyclase; Heme; Hemin; Humans; Interleukin-5; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols | 1999 |
Kinetics of oxidation of aliphatic and aromatic thiols by myeloperoxidase compounds I and II.
Topics: Cysteine; Electrons; Glutathione; Homovanillic Acid; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Neutrophils; Oxidants; Oxidation-Reduction; Penicillamine; Pentetic Acid; Peroxidase; Structure-Activity Relationship; Substrate Specificity; Sulfhydryl Compounds; Thioctic Acid; Thiouridine | 1999 |
Investigations of S-transnitrosylation reactions between low- and high-molecular-weight S-nitroso compounds and their thiols by high-performance liquid chromatography and gas chromatography-mass spectrometry.
Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Cysteine; Erythrocytes; Gas Chromatography-Mass Spectrometry; Glutathione; Homocysteine; Humans; Hydroxylamine; In Vitro Techniques; Kinetics; Molecular Weight; Nitric Oxide; Nitroso Compounds; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Sulfhydryl Compounds | 1999 |
Biochemical characterization of human S-nitrosohemoglobin. Effects on oxygen binding and transnitrosation.
Topics: Allosteric Regulation; Cysteine; Erythrocytes; Ethylmaleimide; Glutathione; Hemoglobins; Humans; Kinetics; Nitrosation; Nitroso Compounds; Oxygen; Penicillamine; S-Nitrosoglutathione; S-Nitrosothiols; Spectrophotometry; Sulfhydryl Compounds; Vasodilation | 1999 |
Critical role of sulfenic acid formation of thiols in the inactivation of glyceraldehyde-3-phosphate dehydrogenase by nitric oxide.
Topics: Binding Sites; Cysteine; Dithiothreitol; Enzyme Repression; Glyceraldehyde-3-Phosphate Dehydrogenases; Hydrogen Peroxide; NAD; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxidation-Reduction; Penicillamine; Sulfenic Acids; Sulfhydryl Compounds | 1999 |
Solution stability of linear vs. cyclic RGD peptides.
Topics: Chromatography, High Pressure Liquid; Cysteine; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Oligopeptides; Penicillamine; Peptides, Cyclic; Protein Conformation; Protein Denaturation; Solubility; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure-Activity Relationship | 1999 |
Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide.
Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cysteamine; Cysteine; Dithiothreitol; Glutathione; Hydrogen Peroxide; Oxygen Consumption; Penicillamine; Reactive Oxygen Species; Sulfhydryl Compounds; Superoxides; Xanthine Oxidase | 1999 |
[Short interval change of 99mTc-ethyl cysteinate dimer single photon emission computed tomography in Wilson's disease].
Topics: Adolescent; Brain; Cysteine; Female; Hepatolenticular Degeneration; Humans; Magnetic Resonance Imaging; Organotechnetium Compounds; Penicillamine; Radiopharmaceuticals; Thalamus; Tomography, Emission-Computed, Single-Photon | 1999 |
A modified cyanide-nitroprusside method for quantifying urinary cystine concentration that corrects for creatinine interference.
Topics: Adult; Artifacts; Ascorbic Acid; Captopril; Chlorides; Colorimetry; Creatinine; Cyanides; Cysteine; Cystinuria; Dose-Response Relationship, Drug; Female; Ferrous Compounds; Humans; Male; Middle Aged; Nitroprusside; Penicillamine; Reference Values; Reproducibility of Results; Serum Albumin; Tiopronin; Zinc Compounds | 1999 |
Calcium channel activation facilitated by nitric oxide in retinal ganglion cells.
Topics: 1-Methyl-3-isobutylxanthine; Ambystoma; Animals; Calcium Channel Blockers; Calcium Channels; Cyclic GMP; Cysteine; In Vitro Techniques; Larva; Membrane Potentials; Nisoldipine; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; omega-Conotoxin GVIA; Patch-Clamp Techniques; Penicillamine; Retinal Ganglion Cells; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Tetrodotoxin; Thionucleotides | 2000 |
Bucillamine suppresses human Th1 cell development by a hydrogen peroxide-independent mechanism.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Cysteine; Flow Cytometry; Humans; Hydrogen Peroxide; Interferon-gamma; Interleukin-12; Interleukin-2; Interleukin-4; Leukocyte Common Antigens; Oxidants; Penicillamine; Th1 Cells | 2000 |
Effects of sulfhydryl compounds on interleukin-1-induced vascular endothelial growth factor production in human synovial stromal cells.
Topics: Acetylcysteine; Cells, Cultured; Cysteine; Endothelial Growth Factors; Humans; Interleukin-1; Lymphokines; Penicillamine; Stromal Cells; Sulfhydryl Compounds; Synovial Membrane; Tiopronin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
In vitro and in vivo inhibition of activation induced T cell apoptosis by bucillamine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; B-Lymphocytes; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cysteine; Dexamethasone; Enterotoxins; Flow Cytometry; Glucocorticoids; Hybridomas; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Penicillamine; Reactive Oxygen Species; Superantigens; Thymus Gland | 2000 |
Nitric oxide mediated modulation of norepinephrine transport: identification of a potential target for S-nitrosylation.
Topics: Amino Acid Sequence; Animals; Biological Transport; Carrier Proteins; CHO Cells; Cricetinae; Cysteine; Molecular Sequence Data; Nitric Oxide; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Penicillamine; Symporters | 2000 |
S-nitroso-l-cysteine releases norepinephrine in rat spinal synaptosomes.
Topics: Adrenergic Uptake Inhibitors; Animals; Binding, Competitive; Calcium; Calmodulin; Cysteine; Desipramine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Egtazic Acid; Leucine; Magnesium; Male; Nickel; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Nomifensine; Norepinephrine; omega-Conotoxins; Penicillamine; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Sodium; Spinal Cord; Synaptosomes | 2000 |
Crystal structure of carboxypeptidase A complexed with D-cysteine at 1.75 A - inhibitor-induced conformational changes.
Topics: Binding Sites; Carboxypeptidases; Carboxypeptidases A; Crystallography; Cysteine; Drug Design; Enzyme Inhibitors; Metalloproteins; Models, Molecular; Motion; Penicillamine; Stereoisomerism; Zinc | 2000 |
Nitric oxide inhibits dystrophin proteolysis by coxsackieviral protease 2A through S-nitrosylation: A protective mechanism against enteroviral cardiomyopathy.
Topics: Animals; Blotting, Western; Cardiomyopathy, Dilated; Catalytic Domain; COS Cells; Cysteine; Cysteine Endopeptidases; Densitometry; Dystrophin; Enterovirus Infections; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Hydrazines; Mice; Nitric Oxide; Nitric Oxide Donors; Nitrogen Oxides; Penicillamine; Peptide Hydrolases; S-Nitroso-N-Acetylpenicillamine; Spermine; Sulfhydryl Compounds; Viral Fusion Proteins; Viral Proteins | 2000 |
Intrathecal S-nitroso-N-acetylpenicillamine and L-cysteine attenuate nerve injury-induced allodynia through noradrenergic activation in rats.
Topics: Animals; Cysteine; Hyperalgesia; Injections, Spinal; Male; Mechanoreceptors; Mercaptoethanol; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Norepinephrine; Pain Threshold; Penicillamine; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; S-Nitrosothiols; Spinal Cord | 2000 |
Nitric oxide negatively regulates c-Jun N-terminal kinase/stress-activated protein kinase by means of S-nitrosylation.
Topics: Animals; Cell Line; Cells, Cultured; Cyclic GMP; Cysteine; Enzyme Activation; Humans; Interferon-gamma; JNK Mitogen-Activated Protein Kinases; Macrophages; Male; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitric Oxide; Nitric Oxide Donors; Oxidation-Reduction; Penicillamine; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds | 2000 |
Nature of cysteine-based Re(V)=O(N2S2) radiopharmaceuticals at physiological pH ascertained by investigation of a new complex with a meso N2S2 ligand having carboxyl groups anti to the oxo group.
Topics: Crystallography, X-Ray; Cysteine; Hydrogen-Ion Concentration; Isomerism; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Organometallic Compounds; Penicillamine; Radiopharmaceuticals; Rhenium; Spectrum Analysis, Raman | 2000 |
Suppression of urease levels in Streptococcus salivarius by cysteine, related compounds and by sulfide.
Topics: Bacterial Proteins; Bacteriological Techniques; Cysteamine; Cysteine; Dental Plaque; Dithiothreitol; Enzyme Inhibitors; Glutathione; Humans; Hydrogen-Ion Concentration; Hydrolysis; Mercaptoethanol; Penicillamine; Periodontal Diseases; Species Specificity; Streptococcus; Sulfides; Urease | 2000 |
Targeting cysteine residues of human immunodeficiency virus type 1 protease by reactive free radical species.
Topics: Bacteria; Cysteine; Electrophoresis, Polyacrylamide Gel; HIV Protease; HIV Protease Inhibitors; Humans; Inclusion Bodies; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Spectrometry, Mass, Electrospray Ionization; Vasodilator Agents | 1999 |
Effects of nitrovasodilators on the human fetal-placental circulation in vitro.
Topics: Adolescent; Adult; Antioxidants; Arteries; Chorion; Cysteine; Female; Fetus; Gestational Age; Glutathione; Humans; In Vitro Techniques; Nitrates; Nitroglycerin; Nitroprusside; Nitroso Compounds; Oxygen; Penicillamine; Placenta; Pregnancy; S-Nitrosoglutathione; Superoxide Dismutase; Vasodilation; Vasodilator Agents | 2001 |
Effects of KE-758; an active metabolite of the new anti-rheumatic drug KE-298, D-penicillamine, bucillamine and auranofin on the proliferation of murine lymphocytes, and the production of nitric oxide by murine macrophages.
Topics: Animals; Antirheumatic Agents; Auranofin; Cell Division; Cell Line; Concanavalin A; Cysteine; Female; Hydrogen Peroxide; In Vitro Techniques; Interferon-gamma; Ionomycin; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Macrophages; Mice; Mice, Inbred DBA; Nitric Oxide; Penicillamine; Phenylpropionates; Recombinant Proteins; Tetradecanoylphorbol Acetate | 2001 |
In vitro activation of soluble guanylyl cyclase and nitric oxide release: a comparison of NO donors and NO mimetics.
Topics: Animals; Aorta; Cysteine; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Glutathione; Guanylate Cyclase; Hydrazines; Indazoles; Molecular Mimicry; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Nitroso Compounds; Penicillamine; Rats; S-Nitrosoglutathione; Solubility | 2001 |
Peroxynitrite-induced tyrosine nitration and inhibition of protein kinase C.
Topics: Animals; Brain; Cysteine; Isoenzymes; Male; Neurodegenerative Diseases; Nitrates; Nitric Oxide Donors; Nitroprusside; Nitroso Compounds; Oxidants; Oxidation-Reduction; Penicillamine; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Rats; Rats, Sprague-Dawley; S-Nitrosothiols; Tissue Extracts; Tyrosine | 2001 |
NO-induced relaxation of labouring and non-labouring human myometrium is not mediated by cyclic GMP.
Topics: Charybdotoxin; Cyclic GMP; Cysteine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Guanylate Cyclase; Humans; In Vitro Techniques; Labor, Obstetric; Molsidomine; Muscle Relaxation; Muscle, Smooth; Myometrium; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxadiazoles; Oxytocin; Penicillamine; Peptides; Pregnancy; Quinoxalines; S-Nitrosothiols; Scorpion Venoms; Time Factors; Uterus | 2001 |
Redox regulation of cytosolic glycerol-3-phosphate dehydrogenase: Cys(102) is the target of the redox control and essential for the catalytic activity.
Topics: Animals; Binding Sites; Catalysis; CHO Cells; Cricetinae; Cysteine; Cystine; Cytosol; Ethylmaleimide; Glutathione; Glycerolphosphate Dehydrogenase; In Vitro Techniques; Nitric Oxide Donors; Oxidation-Reduction; Penicillamine; Sodium Selenite; Transfection | 2002 |
Thiol-induced discharge of acontial nematocytes.
Topics: Alkylating Agents; Animals; Anthozoa; Bites and Stings; Chemoreceptor Cells; Cysteine; Disulfides; Glutathione; Homocysteine; Iodoacetamide; Oxidation-Reduction; Penicillamine; Sulfhydryl Compounds | 2002 |
A new, potent urotensin II receptor peptide agonist containing a Pen residue at the disulfide bridge.
Topics: Animals; Binding, Competitive; CHO Cells; Cricetinae; Cysteine; Disulfides; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Oligopeptides; Penicillamine; Peptides, Cyclic; Radioligand Assay; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Structure-Activity Relationship | 2002 |
KE-758, an active metabolite of the new anti-rheumatic drug KE-298, suppresses production of tumor necrosis factor-alpha and interleukin-1 beta in THP-1, a human monocyte cell line.
Topics: Antirheumatic Agents; Auranofin; Cell Line; Cysteine; Enzyme-Linked Immunosorbent Assay; Humans; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Monocytes; Penicillamine; Phenylbutyrates; Phenylpropionates; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha | 2002 |
A new mixed disulphide: penicillamine-cysteine.
Topics: Cysteine; Disulfides; Penicillamine; Penicillins; Sulfides | 1954 |
An increased vitamin B6 requirement in the rat on a diet containing L-penicillamine.
Topics: Animals; Cysteine; Diet; Penicillamine; Rats; Vitamin B 6 | 1957 |
An anti-vitamin B6 action of L-penicillamine.
Topics: Cysteine; Penicillamine; Vitamin B 6 | 1957 |
L-penicillamine and rat liver transaminase activity.
Topics: Animals; Cysteine; Liver; Penicillamine; Rats; Transaminases | 1957 |
The inhibition of serine metabolism in Leuconostoc mesenteroides P-60. I. Microbiological activity of D- and L-penicillamine.
Topics: Cysteine; Leuconostoc; Penicillamine; Serine | 1957 |
The treatment of hepatolenticular degeneration with penicillamine; with report of two cases.
Topics: Cysteine; Hepatolenticular Degeneration; Humans; Penicillamine | 1958 |
Effects of penicillamine and dimercaprol on turnover of copper in patients with Wilson's disease.
Topics: Copper; Cysteine; Dimercaprol; Hepatolenticular Degeneration; Humans; Penicillamine | 1958 |
Protection by D-penicillamine against the lethal effects of mercuric chloride.
Topics: Cysteine; Humans; Mercuric Chloride; Mercury; Mercury Poisoning; Penicillamine | 1958 |
The inhibition of Escherichia coli by 1-penicillamine and its reversal by isoleucine, valine or leucine.
Topics: Cysteine; Escherichia coli; Isoleucine; Leucine; Penicillamine; Valine | 1958 |
A comparison of intravenous calcium disodium versenate and oral penicillamine in promoting elimination of lead.
Topics: Biological Transport; Cysteine; Edetic Acid; Lead Poisoning; Penicillamine | 1958 |
Clinical studies with penicillamine in hepatolenticular degeneration.
Topics: Biomedical Research; Cysteine; Hepatolenticular Degeneration; Penicillamine | 1959 |
N-acetyl-DL-penicillamine, a new oral protective agent against the lethal effects of mercuric chloride.
Topics: Cysteine; Humans; Mercuric Chloride; Mercury; Penicillamine; Protective Agents; Valine | 1959 |
Formation of D-penicillamine-cysteine mixed disulphide by reaction of D-benzylpenicilloic acid with cystine.
Topics: Cysteine; Cystine; Disulfides; Penicillamine; Penicillin G; Penicillins; Valine | 1960 |
PENICILLAMINE AND MIXED DISULPHIDE EXCRETION IN WILSON'S DISEASE.
Topics: Cysteine; Cystinuria; Disulfides; Hepatolenticular Degeneration; Humans; Penicillamine; Sulfides | 1963 |
THE REACTION OF THIOL AMINO ACIDS WITH PYRIDOXAL 5'-PHOSPHATE IN THE ABSENCE AND IN THE PRESENCE OF L-GLUTAMIC ACID.
Topics: Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Glutamates; Glutamic Acid; Penicillamine; Phosphates; Pyridoxal Phosphate; Research; Sulfhydryl Compounds | 1963 |
PROTECTION AGAINST NITROGEN MUSTARD BY CYSTEINE AND RELATED SUBSTANCES, INVESTIGATED USING (3H)METHYL-DI-(2-CHLOROETHYL) AMINE.
Topics: Amines; Cystamine; Cysteamine; Cysteine; Mechlorethamine; Mice; Penicillamine; Pharmacology; Radiation-Protective Agents; Research; Tritium | 1963 |
[METAL COMPLEXES OF DRUGS].
Topics: Chemistry, Pharmaceutical; Coordination Complexes; Cysteine; Metals; Penicillamine; Pharmacy; Research; Zinc | 1964 |
STUDIES ON METAL COMPLEXES OF DRUGS; D-PENICILLAMINE AND N-ACETYL-D-PENICILLAMINE.
Topics: Chemistry, Pharmaceutical; Cobalt; Coordination Complexes; Cysteine; Iron; Lead; Manganese; Mercury; Nickel; Penicillamine; Zinc | 1964 |
SPECTROPHOTOMETRIC DETERMINATION OF DISULFIDES, SULFINIC ACIDS, THIO ETHERS, AND THIOLS WITH THE PALLADIUM (II) ION.
Topics: Benzoates; Cysteamine; Cysteine; Cystine; Disulfides; Ethers; Glutathione; Homocysteine; Lactones; Methionine; Palladium; Penicillamine; Phosphates; Research; Spectrophotometry; Sulfhydryl Compounds; Sulfides; Sulfinic Acids; Sulfites; Thiosulfates | 1964 |
METAL CHELATES OF SOME SULFUR-CONTAINING AMINO ACIDS.
Topics: Acetates; Amino Acids; Cadmium; Calcium; Chelating Agents; Cobalt; Copper; Cysteine; Ethionine; Lead; Magnesium; Manganese; Mercury; Metals; Methionine; Nickel; Penicillamine; Potentiometry; Propionates; Research; Silver; Strontium; Sulfur; Zinc | 1964 |
EFFECT OF THIOLS ON EXTRACTION AND ACTIVITY OF OX-KIDNEY URATE OXIDASE.
Topics: Chemical Phenomena; Chemistry; Cysteine; Dimercaprol; Glutathione; Kidney; Oxidoreductases; Penicillamine; Pharmacology; Research; Sulfhydryl Compounds; Urate Oxidase | 1964 |
CYSTINURIA: EFFECT OF D-PENICILLAMINE ON PLASMA AND URINARY CYSTINE CONCENTRATIONS.
Topics: Arginine; Blood; Cysteine; Cystine; Cystinuria; Drug Therapy; Humans; Lysine; Penicillamine; Sulfides; Urine | 1965 |
EFFECT OF PENICILLAMINE ON CYSTINURIA.
Topics: Arginine; Body Fluids; Cysteine; Cystinuria; Drug Therapy; Homocysteine; Humans; Lysine; Ornithine; Penicillamine; Urine | 1965 |
METHODS OF DIMINISHING CYSTINE EXCRETION IN CYSTINURIA.
Topics: Acetylcysteine; Amino Acids; Cysteine; Cystine; Cystinuria; Diet; Diet Therapy; Drug Therapy; Fluids and Secretions; Indoles; Oxandrolone; Penicillamine; Rats; Sulfur; Vitamin B 6 Deficiency | 1965 |
DEFICIENCIES OF -SH-DEPENDENT ENZYMES IN CYSTINOSIS.
Topics: Alcohol Oxidoreductases; Alkaline Phosphatase; Child; Coenzyme A; Cysteine; Cystine; Cystinosis; Dimercaprol; Electron Transport Complex II; Enzymes; Glucose-6-Phosphatase; Glycerolphosphate Dehydrogenase; Hexokinase; Hydro-Lyases; Kidney; Leucyl Aminopeptidase; Liver; Muscles; Penicillamine; Pharmacology; Phosphogluconate Dehydrogenase; Succinate Dehydrogenase; Sulfhydryl Compounds; Tissue Extracts; Transaminases | 1965 |
[The effects of penicillamine and versenate in the treatment of Wilson's disease and lead poisoning].
Topics: Cysteine; Edetic Acid; Hepatolenticular Degeneration; Humans; Lead Poisoning; Penicillamine | 1959 |
Inhibition of apoptosis signal-regulating kinase 1 by nitric oxide through a thiol redox mechanism.
Topics: Animals; Cell Line; Cysteine; Enzyme Activation; Enzyme Inhibitors; Fibrosarcoma; Humans; Hydrogen Peroxide; Interferon-gamma; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; Mice; Mutagenesis, Site-Directed; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Oxidation-Reduction; Penicillamine; Structure-Activity Relationship; Sulfhydryl Compounds; Transfection; Tumor Cells, Cultured | 2004 |
Photofragmentation of C,N-protected alpha-amino acids: comparing tert-leucine with sulfur-containing amino acids methionine and cysteine.
Topics: Acetonitriles; Cysteine; Electron Transport; Esters; Glycine; Leucine; Methanol; Methionine; Methylation; Penicillamine; Photolysis; Sulfhydryl Compounds | 2003 |
The mechanisms of S-nitrosothiol decomposition catalyzed by iron.
Topics: Catalysis; Cysteine; Electron Spin Resonance Spectroscopy; Hemoglobins; Iron; Kinetics; Nitrogen Oxides; Penicillamine; S-Nitrosoglutathione; S-Nitrosothiols; Sorbitol; Spectrophotometry, Ultraviolet; Spin Labels; Thiocarbamates | 2004 |
Nitric oxide represses inhibitory kappaB kinase through S-nitrosylation.
Topics: Amino Acid Substitution; Animals; Cell Line; Cysteine; Enzyme Inhibitors; Epithelial Cells; Humans; I-kappa B Kinase; I-kappa B Proteins; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Mice; Mitogen-Activated Protein Kinases; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; omega-N-Methylarginine; Penicillamine; Protein Serine-Threonine Kinases; Pulmonary Alveoli; Recombinant Proteins; S-Nitrosothiols; Tumor Necrosis Factor-alpha | 2004 |
The effect of cysteine analogues on the excretion of urinary sulphate in the rat following cysteine administration.
Topics: Animals; Anti-Infective Agents, Local; Antirheumatic Agents; Carbocysteine; Cysteine; Drug Interactions; Injections, Intraperitoneal; Male; Models, Chemical; Penicillamine; Rats; Rats, Wistar; Sulfates; Valine | 2004 |
Comparison of cysteine and penicillamine ligands in a Co(II) maquette.
Topics: Amino Acid Sequence; Cobalt; Cysteine; Ligands; Metalloproteins; Models, Molecular; Molecular Structure; Penicillamine; Protein Conformation; Spectrophotometry, Ultraviolet | 2004 |
Linkage isomerism, structure, and reactivity studies of sulfenamide complexes of cobalt(III).
Topics: Cobalt; Crystallography, X-Ray; Cysteine; Hydrogen-Ion Concentration; Isomerism; Kinetics; Models, Chemical; Molecular Conformation; Molecular Structure; Organometallic Compounds; Penicillamine; Sulfamerazine | 2004 |
N-Salicylideneamino acidato complexes of oxovanadium(IV). The cysteine and penicillamine complexes.
Topics: Aldehydes; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Circular Dichroism; Cysteine; Ligands; Penicillamine; Vanadates | 2004 |
Platinum particles-modified electrode for HPLC with pulsed amperometric detection of thiols in rat striatum.
Topics: Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Cysteine; Electrochemistry; Electrodes; Glutathione; Oxidation-Reduction; Penicillamine; Platinum; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Sensitivity and Specificity; Sulfhydryl Compounds; Time Factors | 2004 |
S-nitrosylation-dependent inactivation of Akt/protein kinase B in insulin resistance.
Topics: 3T3 Cells; Adipocytes; Animals; Cell Line, Tumor; Cells, Cultured; COS Cells; Cysteine; Diabetes Mellitus, Experimental; DNA, Complementary; Extracellular Signal-Regulated MAP Kinases; Immunoblotting; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscle, Skeletal; Mutation; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen; Oxidative Stress; Penicillamine; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Time Factors; Transfection | 2005 |
Synthesis, characterization, and controlled nitric oxide release from S-nitrosothiol-derivatized fumed silica polymer filler particles.
Topics: Acetylcysteine; Biocompatible Materials; Copper; Cysteine; Nitric Oxide; Nitric Oxide Donors; Particle Size; Penicillamine; Photochemistry; Platelet Aggregation Inhibitors; Polymers; S-Nitrosothiols; Silicon Dioxide | 2005 |
Effect of cystine-binding thiol drugs on urinary cystine capacity in patients with cystinuria.
Topics: Administration, Oral; Adult; Captopril; Case-Control Studies; Cysteine; Cystinuria; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Male; Middle Aged; Penicillamine; Probability; Prospective Studies; Reference Values; Risk Assessment; Tiopronin; Treatment Outcome; Urinalysis | 2005 |
S-nitrosylation of N-ethylmaleimide sensitive factor mediates surface expression of AMPA receptors.
Topics: Adenylyl Imidodiphosphate; Aldehydes; Animals; Blotting, Western; Cells, Cultured; Cerebellum; Cysteine; Diagnostic Imaging; Dizocilpine Maleate; Drug Interactions; Embryo, Mammalian; Enzyme Activation; Enzyme Inhibitors; Epoxy Compounds; Ethylmaleimide; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hippocampus; Immunoprecipitation; Mice; Mice, Knockout; Mutagenesis; N-Ethylmaleimide-Sensitive Proteins; Nerve Tissue Proteins; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Penicillamine; Protein Binding; Rats; Receptors, AMPA; Recombinant Fusion Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfhydryl Reagents; Time Factors; Transfection; Vesicular Transport Proteins | 2005 |
The inhibitory effect of disease-modifying anti-rheumatic drugs and steroids on gliostatin/platelet-derived endothelial cell growth factor production in human fibroblast-like synoviocytes.
Topics: Adrenal Cortex Hormones; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cells; Cells, Cultured; Cysteine; Dexamethasone; Elbow; Female; Fibroblasts; Humans; Knee; Methotrexate; Middle Aged; Organogold Compounds; Orthopedic Procedures; Penicillamine; Phenylacetates; Sulfasalazine; Synovial Membrane; Thymidine Phosphorylase | 2005 |
Induction of cysteine dioxygenase activity by oral administration of cysteine analogues to the rat: implications for drug efficacy and safety.
Topics: Administration, Oral; Animals; Anti-Infective Agents, Local; Antirheumatic Agents; Carbocysteine; Cysteine; Cysteine Dioxygenase; Cysteine Synthase; Cytosol; Drug Administration Schedule; Enzyme Activation; Liver; Male; Oxidation-Reduction; Penicillamine; Rats; Sulfur | 2005 |
Subcortical white matter abnormalities related to drug resistance in Wilson disease.
Topics: Adenosine Triphosphatases; Antidotes; Brain; Cation Transport Proteins; Child; Copper-Transporting ATPases; Cysteine; Disease Progression; Drug Resistance; Follow-Up Studies; Hepatolenticular Degeneration; Humans; Magnetic Resonance Imaging; Male; Penicillamine | 2006 |
Kinetics of the reaction between nitroxide and thiyl radicals: nitroxides as antioxidants in the presence of thiols.
Topics: Antioxidants; Cysteine; Free Radicals; Glutathione; Kinetics; Molecular Structure; Nitrogen Oxides; Penicillamine; Stereoisomerism; Sulfhydryl Compounds; Time Factors | 2008 |
Analytical and preparative enantioseparation of DL-penicillamine and DL-cysteine by high-performance liquid chromatography on alpha-acid glycoprotein and beta-cyclodextrin columns using ninhydrin as a reversible tagging reagent.
Topics: beta-Cyclodextrins; Chromatography, High Pressure Liquid; Cysteine; Dinitrophenols; Glycoproteins; Hydrogen-Ion Concentration; Ninhydrin; Penicillamine; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Zinc | 2009 |
Theoretical and experimental sulfur K-edge X-ray absorption spectroscopic study of cysteine, cystine, homocysteine, penicillamine, methionine and methionine sulfoxide.
Topics: Cysteine; Cystine; Homocysteine; Hydrogen-Ion Concentration; Mercury; Methionine; Molecular Conformation; Nickel; Penicillamine; Protons; Spectrometry, X-Ray Emission; Sulfur Compounds; Water | 2009 |
Cadmium(II) complex formation with cysteine and penicillamine.
Topics: Cadmium; Cysteine; Magnetic Resonance Spectroscopy; Penicillamine; Spectrum Analysis; X-Rays | 2009 |
Synthesis and linkage isomerization of thiolato-bridged Ru(II)Ag(I)Ru(II) trinuclear complex with D-penicillaminate.
Topics: Chelating Agents; Circular Dichroism; Cysteine; Ethanol; Isomerism; Molecular Structure; Penicillamine; Perchlorates; Ruthenium; Silver; Stereoisomerism; Sulfhydryl Compounds; Water | 2009 |
Novel twist on the biotin switch cracks endothelial cell S-nitrosoproteome.
Topics: Biotin; Cysteine; Penicillamine; Proteins; Proteomics; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols | 2009 |
A multinuclear coordination system of L-cysteine and L-penicillamine that induce opposite chiralities at metal centers.
Topics: Cysteine; Metals; Penicillamine; Stereoisomerism | 2009 |
Autoxidation of thiol-containing amino acid to its disulfide derivative that links two copper(II) centers: the important role of auxiliary ligand.
Topics: 2,2'-Dipyridyl; Amino Acids; Copper; Crystallography, X-Ray; Cysteine; Disulfides; Ligands; Molecular Conformation; Oxidation-Reduction; Penicillamine; Sulfhydryl Compounds | 2010 |
Chiral self assembled monolayers as resolving auxiliaries in the crystallization of valine.
Topics: Acetylcysteine; Crystallization; Cysteine; Glutathione; Gold; Penicillamine; Solubility; Stereoisomerism; Valine | 2010 |
Synthesis of a new alpha-amino acid, S-methyl-betabeta dimethylcysteine.
Topics: Amino Acids; Cysteine; Penicillamine | 1946 |
D-penicillamine interferes with S-homocysteinylation and S-cysteinylation of LDL apolipoprotein B.
Topics: Apolipoproteins B; Cysteine; Hepatolenticular Degeneration; Homocysteine; Humans; Penicillamine; Sulfhydryl Compounds | 2011 |
Synthesis of (S)-naproxen-benzotriazole and its application as chiral derivatizing reagent for microwave-assisted synthesis and indirect high performance liquid chromatographic separation of diastereomers of penicillamine, cysteine and homocysteine.
Topics: Chromatography, High Pressure Liquid; Cysteine; Homocysteine; Hydrogen-Ion Concentration; Linear Models; Methanol; Microwaves; Naproxen; Penicillamine; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism; Triazoles | 2011 |
Free-radical degradation of high-molecular-weight hyaluronan induced by ascorbate plus cupric ions. Testing of bucillamine and its SA981-metabolite as antioxidants.
Topics: Antioxidants; Antirheumatic Agents; Ascorbic Acid; Cations; Copper; Cysteine; Free Radicals; Hyaluronic Acid; Hydroxyl Radical; Molecular Weight; Oxidation-Reduction; Penicillamine; Peroxides; Viscosity | 2011 |
Application of an unusual ninhydrin-based reaction for the indirect chiral resolution of D,L-penicillamine.
Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cysteine; Ninhydrin; Penicillamine; Stereoisomerism | 2011 |
Synthesis, characterization and biological evaluation of novel neutral fac-M(CO)3(SNO) complexes (M=Re, 99mTc) bearing the o-methoxyphenylpiperazine moiety.
Topics: Animals; Cysteine; Isotope Labeling; Male; Metabolic Clearance Rate; Organ Specificity; Penicillamine; Propiophenones; Radiopharmaceuticals; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Technetium; Tissue Distribution | 2012 |
Enantioseparations by high-performance liquid chromatography based on chiral ligand-exchange.
Topics: Chromatography, High Pressure Liquid; Cysteine; Hydroxyproline; Ligands; Molecular Structure; Penicillamine; Phenylalanine; Proline; Silica Gel; Stereoisomerism | 2013 |
Silver(I) complex formation with cysteine, penicillamine, and glutathione.
Topics: Coordination Complexes; Cysteine; Glutathione; Magnetic Resonance Spectroscopy; Models, Molecular; Penicillamine; Silver; X-Ray Absorption Spectroscopy | 2013 |
A new BODIPY-based long-wavelength fluorescent probe for chromatographic analysis of low-molecular-weight thiols.
Topics: Acetylcysteine; Animals; Boron Compounds; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cysteine; Dipeptides; Fluorescent Dyes; Glutathione; Homocysteine; Iodoacetamide; Limit of Detection; Male; Mice; Penicillamine; Sulfhydryl Compounds | 2014 |
Bio-inspired nitrile hydration by peptidic ligands based on L-cysteine, L-methionine or L-penicillamine and pyridine-2,6-dicarboxylic acid.
Topics: Acetamides; Acetonitriles; Biocatalysis; Catalytic Domain; Cobalt; Cysteine; Hydro-Lyases; Iron; Methionine; Models, Molecular; Molecular Mimicry; Oxidation-Reduction; Penicillamine; Picolinic Acids | 2014 |
Formation constants of copper(I) complexes with cysteine, penicillamine and glutathione: implications for copper speciation in the human eye.
Topics: Computer Simulation; Coordination Complexes; Copper; Cysteine; Eye; Glutathione; Humans; Hydrogen-Ion Concentration; Models, Biological; Penicillamine; Potentiometry | 2015 |
Orthogonal Cysteine-Penicillamine Disulfide Pairing for Directing the Oxidative Folding of Peptides.
Topics: Cysteine; Oxidation-Reduction; Penicillamine; Peptides; Protein Folding | 2015 |
The influence of penicillamine/cysteine mutation on the metal complexes of peptides.
Topics: Amino Acid Sequence; Cadmium; Circular Dichroism; Coordination Complexes; Cysteine; Hydrogen-Ion Concentration; Molecular Conformation; Nickel; Penicillamine; Peptides; Potentiometry; Spectrometry, Mass, Electrospray Ionization; Zinc | 2017 |
A phage display-based strategy for the de novo creation of disulfide-constrained and isomer-free bicyclic peptide affinity reagents.
Topics: Amino Acid Sequence; Bridged Bicyclo Compounds, Heterocyclic; Cell Surface Display Techniques; Consensus Sequence; Cysteine; Disulfides; Isomerism; Kelch-Like ECH-Associated Protein 1; Ligands; Oxidation-Reduction; Penicillamine; Peptides, Cyclic | 2018 |
Nanoparticle-based Chemiluminescence for Chiral Discrimination of Thiol-Containing Amino Acids.
Topics: Cadmium Compounds; Cysteine; Humans; Luminescence; Luminescent Measurements; Nanoparticles; Penicillamine; Quantum Dots; Tablets; Tellurium; Urinalysis | 2018 |
Cysteine/Penicillamine Ligation Independent of Terminal Steric Demands for Chemical Protein Synthesis.
Topics: Aldehydes; Amino Acid Sequence; Cysteine; Penicillamine; Peptide Fragments; Programmed Cell Death 1 Receptor; Proteins | 2020 |
Serine/Threonine Ligation and Cysteine/Penicillamine Ligation.
Topics: Cysteine; Esters; Penicillamine; Peptides; Serine; Threonine | 2022 |
Glutathione, Cysteine, and D-Penicillamine Role in Exchange of Silver Metal from the Albumin Metal Complex.
Topics: Acetylcysteine; Coordination Complexes; Cysteine; Glutathione; Metals; Penicillamine; Serum Albumin, Bovine; Silver Nitrate; Sulfhydryl Compounds | 2022 |
Acetylenic TACE inhibitors. Part 2: SAR of six-membered cyclic sulfonamide hydroxamates.
Topics: ADAM Proteins; ADAM17 Protein; Animals; Biological Availability; Caspase Inhibitors; Cell Line; Crystallography, X-Ray; Cysteine Proteinase Inhibitors; Dogs; Humans; Hydroxamic Acids; Inhibitory Concentration 50; Lipopolysaccharides; Mice; Molecular Structure; Monocytes; Rats; Species Specificity; Structure-Activity Relationship; Sulfonamides; Tumor Necrosis Factor-alpha | 2005 |
N-Terminal 2,3-diaminopropionic acid (Dap) peptides as efficient methylglyoxal scavengers to inhibit advanced glycation endproduct (AGE) formation.
Topics: beta-Alanine; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Glycation End Products, Advanced; Magnetic Resonance Spectroscopy; Peptides; Pyruvaldehyde | 2009 |