penicillamine and copper sulfate

penicillamine has been researched along with copper sulfate in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19906 (25.00)18.7374
1990's7 (29.17)18.2507
2000's10 (41.67)29.6817
2010's0 (0.00)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Reed, VD; Smith, RC1
Newton, K; Pullar, T; Toothill, C; Wright, V; Wrigley, H1
Yamamoto, I; Yamauchi, T1
Hirohata, K; Matsubara, T; Saura, R; Ziff, M1
Lipsky, PE1
Eskola, J; Lehtonen, OP; Leino, R; Soppi, E1
Hirohata, K; Matsubara, T1
Messner, RP; Staite, ND; Zoschke, DC1
Dew, G; Duncan, S; Hunter, T; Reynolds, JJ1
Akamatsu, T; Matsubara, T; Mizuno, K; Saegusa, Y1
Hantson, P; Lievens, M; Mahieu, P1
Al-Sa'doni, HH; Butler, AR; Flitney, FW; Megson, IL1
Aaseth, J; Afanas'ev, IB; Korkina, LG1
Bando, Y; Chone, Y; Izumi, K; Jiao, Z; Kinouchi, T; Kitaura, K; Minami, T; Mochizuki, M; Ohnishi, Y; Suzuki, Y; Uehara, H; Yamada, T1
Shimazaki, S; Takeda, T; Yukioka, T1
Buglass, AJ; Lee, SH1
Martin, W; McIntosh, L; Nelli, S1
Bonfante-Cabarcas, R; Castañeda-Perozo, D; Gutiérrez-Reyes, E; Moreno-Yanez, J; Nello-Pérez, C; Papale-Centofanti, J; Pascuzzo-Lima, C1
Avella, M; Botham, KM; Elliott, J; Goulter, AB1
Allaouchiche, B; Chassard, D; Faure, A; Mathon, L; Poupelin, JC1
Lui, EM; Suntres, ZE1
Gupte, A; Mumper, RJ2
Hans, R; Kaur, A; Pannu, AK; Selvam, S; Shankar, JA; Tyagi, L1

Trials

1 trial(s) available for penicillamine and copper sulfate

ArticleYear
A study of adjunctive copper sulphate treatment in patients with rheumatoid arthritis who have relapsed while taking D-penicillamine.
    British journal of clinical pharmacology, 1991, Volume: 31, Issue:1

    Topics: Adult; Aged; Arthritis, Rheumatoid; Copper; Copper Sulfate; Double-Blind Method; Drug Therapy, Combination; Humans; Middle Aged; Penicillamine; Recurrence

1991

Other Studies

23 other study(ies) available for penicillamine and copper sulfate

ArticleYear
Inhibition by thiols of copper(II)-induced oxidation of oxyhemoglobin.
    Chemico-biological interactions, 1992, Apr-15, Volume: 82, Issue:2

    Topics: Animals; Antioxidants; Cattle; Copper; Copper Sulfate; Methemoglobin; Oxidation-Reduction; Oxyhemoglobins; Penicillamine; Sulfhydryl Compounds; Uric Acid

1992
CuSO4 as an inhibitor of B cell proliferation.
    Japanese journal of pharmacology, 1990, Volume: 54, Issue:4

    Topics: Animals; B-Lymphocytes; Concanavalin A; Copper; Copper Sulfate; Female; Hemolytic Plaque Technique; Immunosuppression Therapy; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Penicillamine; Spleen

1990
Inhibition of human endothelial cell proliferation in vitro and neovascularization in vivo by D-penicillamine.
    The Journal of clinical investigation, 1989, Volume: 83, Issue:1

    Topics: Catalase; Cell Division; Copper; Copper Sulfate; Disulfides; DNA Replication; Drug Synergism; Endothelium, Vascular; Gold Sodium Thiomalate; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Neovascularization, Pathologic; Penicillamine; Sulfhydryl Compounds

1989
Suggested mode of action of D-penicillamine as an immunosuppressive agent in rheumatoid arthritis.
    Zeitschrift fur Rheumatologie, 1988, Volume: 47 Suppl 1

    Topics: Arthritis, Rheumatoid; Ceruloplasmin; Copper; Copper Sulfate; DNA Replication; Humans; Hydrogen Peroxide; Killer Cells, Natural; Lymphocyte Activation; Penicillamine; Synovial Membrane; T-Lymphocytes; T-Lymphocytes, Helper-Inducer

1988
Immune functions in inflammatory bowel and coeliac diseases.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 1988, Volume: 96, Issue:9

    Topics: Adult; Aged; Antibody Formation; Antigens, Differentiation; Celiac Disease; Colitis, Ulcerative; Concanavalin A; Copper; Copper Sulfate; Crohn Disease; Female; Humans; Immunoglobulins; Leukocyte Count; Lymphocyte Activation; Lymphocytes; Male; Middle Aged; Penicillamine; Phytohemagglutinins

1988
Suppression of human fibroblast proliferation by D-penicillamine and copper sulfate in vitro.
    Arthritis and rheumatism, 1988, Volume: 31, Issue:8

    Topics: Cell Division; Copper; Copper Sulfate; Depression, Chemical; DNA; Fibroblasts; Humans; Hydrogen Peroxide; In Vitro Techniques; Interleukin-1; Penicillamine; Phagocytes

1988
In vitro production and scavenging of hydrogen peroxide by D-penicillamine. Relationship to copper availability.
    Arthritis and rheumatism, 1985, Volume: 28, Issue:8

    Topics: Ceruloplasmin; Concanavalin A; Copper; Copper Sulfate; Cysteine; Humans; Hydrogen Peroxide; Lymphocyte Activation; Monocytes; Penicillamine; Time Factors

1985
The effects of antirheumatic drugs on the production of collagenase and tissue inhibitor of metalloproteinases (TIMP) by stimulated rabbit articular chrondrocytes.
    The Journal of rheumatology, 1984, Volume: 11, Issue:1

    Topics: Anti-Inflammatory Agents; Cartilage, Articular; Cells, Cultured; Chloroquine; Concanavalin A; Copper; Copper Sulfate; Dexamethasone; Enzyme Inhibitors; Gold Sodium Thiomalate; Humans; Microbial Collagenase; Penicillamine; Tissue Inhibitor of Metalloproteinases

1984
Inhibition of mitogen-induced response of human peripheral blood mononuclear cells by bucillamine, a new antirheumatic sulfhydryl drug.
    Rheumatology international, 1994, Volume: 13, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Copper; Copper Sulfate; Cysteine; DNA; Humans; Hydrogen Peroxide; Leukocytes, Mononuclear; Mitogens; Penicillamine; Phytohemagglutinins

1994
Accidental ingestion of a zinc and copper sulfate preparation.
    Journal of toxicology. Clinical toxicology, 1996, Volume: 34, Issue:6

    Topics: Aged; Aged, 80 and over; Cardiovascular System; Chelating Agents; Copper Sulfate; Digestive System; Dimercaprol; Female; Humans; Inflammation; Penicillamine; Poisoning; Renal Insufficiency; Respiratory Tract Diseases; Zinc

1996
Synthesis, decomposition, and vasodilator action of some new S-nitrosated dipeptides.
    Nitric oxide : biology and chemistry, 1998, Volume: 2, Issue:3

    Topics: Animals; Copper Sulfate; Dipeptides; Hemoglobins; In Vitro Techniques; Male; Nitric Oxide; Nitrosation; Penicillamine; Rats; Rats, Wistar; Vasodilation; Vasodilator Agents

1998
Hemolytic activity of copper sulfate as influenced by epinephrine and chelating thiols.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1998, Volume: 19, Issue:3

    Topics: Adult; Antidotes; Ceruloplasmin; Chelating Agents; Copper Sulfate; Drug Synergism; Epinephrine; Hemolysis; Homocysteine; Humans; Penicillamine; Succimer

1998
Low susceptibility of Long-Evans Cinnamon rats to N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder carcinogenesis and inhibitory effect of urinary copper.
    Japanese journal of cancer research : Gann, 2000, Volume: 91, Issue:1

    Topics: Age Factors; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Chelating Agents; Copper; Copper Sulfate; Disease Susceptibility; Hydrogen-Ion Concentration; Iron; Male; Metallothionein; Penicillamine; Rats; Rats, Inbred F344; Rats, Inbred LEC; Rats, Long-Evans; Species Specificity; Urinary Bladder Neoplasms; Urine; Zinc

2000
Cupric sulfate intoxication with rhabdomyolysis, treated with chelating agents and blood purification.
    Internal medicine (Tokyo, Japan), 2000, Volume: 39, Issue:3

    Topics: Acute Disease; Adolescent; Chelating Agents; Copper Sulfate; Dimercaprol; Drug Therapy, Combination; Hemodiafiltration; Hemoperfusion; Humans; Male; Penicillamine; Poisoning; Rhabdomyolysis

2000
Elimination of amino acid interferences in the chiral ligand-exchange chromatographic analysis of lactic acid enantiomers in wine.
    Journal of chromatographic science, 2000, Volume: 38, Issue:5

    Topics: Amino Acids; Aspartic Acid; Cations; Chromatography, Liquid; Copper Sulfate; False Positive Reactions; Fermentation; Indicators and Reagents; Ion Exchange; Lactic Acid; Penicillamine; Quality Control; Silicon Dioxide; Stereoisomerism; Wine

2000
Role of copper ions and cytochrome P450 in the vasodilator actions of the nitroxyl anion generator, Angeli's salt, on rat aorta.
    European journal of pharmacology, 2001, Feb-02, Volume: 412, Issue:3

    Topics: Animals; Aorta; Chelating Agents; Chlorides; Copper Sulfate; Cuprizone; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Edetic Acid; Estradiol; Free Radical Scavengers; In Vitro Techniques; Male; Manganese Compounds; Nitric Oxide Donors; Nitrites; Oxidation-Reduction; Penicillamine; Phenanthrolines; Proadifen; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sodium Azide; Superoxide Dismutase; Vasodilation

2001
Supersensitivity of the cholinergic muscarinic system in the rat's brain is induced by high concentrations of Cu+2.
    Investigacion clinica, 2002, Volume: 43, Issue:2

    Topics: Animals; Atropine; Brain Chemistry; Cerebral Cortex; Chelating Agents; Cholinergic Fibers; Copper Sulfate; Corpus Striatum; Dose-Response Relationship, Drug; Hippocampus; Male; Maze Learning; Memory; Motor Activity; Muscarinic Agonists; Muscarinic Antagonists; Nerve Tissue Proteins; Penicillamine; Pyridoxine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Zinc Sulfate

2002
Chylomicron-remnant-like particles inhibit the basal nitric oxide pathway in porcine coronary artery and aortic endothelial cells.
    Clinical science (London, England : 1979), 2003, Volume: 105, Issue:3

    Topics: Animals; Aorta; Arteriosclerosis; Cells, Cultured; Chylomicron Remnants; Chylomicrons; Copper Sulfate; Coronary Vessels; Endothelium, Vascular; Female; In Vitro Techniques; Lipoproteins; Male; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Oxidation-Reduction; Penicillamine; Swine

2003
[Acute cupric sulfate intoxication: pathophysiology and therapy about a case report].
    Annales francaises d'anesthesie et de reanimation, 2003, Volume: 22, Issue:6

    Topics: Adult; Chelating Agents; Copper Sulfate; Erythrocyte Transfusion; Hemolysis; Humans; Intellectual Disability; Male; Meningitis; Nausea; Penicillamine; Poisoning; Vomiting

2003
Prooxidative effect of copper--metallothionein in the acute cytotoxicity of hydrogen peroxide in Ehrlich ascites tumour cells.
    Toxicology, 2006, Jan-16, Volume: 217, Issue:2-3

    Topics: Animals; Calcium; Carcinoma, Ehrlich Tumor; Cell Survival; Copper; Copper Sulfate; Deferoxamine; Dose-Response Relationship, Drug; Glutathione Disulfide; Hydrogen Peroxide; Injections, Intraperitoneal; Iron; Lipid Peroxidation; Male; Mannitol; Metallothionein; Mice; Oxidative Stress; Penicillamine; Pinocytosis; Time Factors; Tumor Cells, Cultured; Zinc

2006
An investigation into copper catalyzed D-penicillamine oxidation and subsequent hydrogen peroxide generation.
    Journal of inorganic biochemistry, 2007, Volume: 101, Issue:4

    Topics: Breast Neoplasms; Catalysis; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Copper; Copper Sulfate; Edetic Acid; Female; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Iron; Oxidation-Reduction; Penicillamine; Reactive Oxygen Species; Temperature

2007
Copper chelation by D-penicillamine generates reactive oxygen species that are cytotoxic to human leukemia and breast cancer cells.
    Free radical biology & medicine, 2007, Nov-01, Volume: 43, Issue:9

    Topics: Breast Neoplasms; Cell Line, Tumor; Chelating Agents; Copper Sulfate; HL-60 Cells; Humans; Hydrogen Peroxide; Leukemia; Penicillamine; Reactive Oxygen Species; Sulfhydryl Compounds

2007
Severe copper sulphate poisoning: A case rescued with plasmapheresis.
    Tropical doctor, 2023, Volume: 53, Issue:2

    Topics: Copper; Copper Sulfate; Humans; Penicillamine; Plasmapheresis; Poisoning; Sulfates

2023