penicillamine and bucillamine

penicillamine has been researched along with bucillamine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19905 (16.13)18.7374
1990's14 (45.16)18.2507
2000's10 (32.26)29.6817
2010's1 (3.23)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Funakoshi, T; Kiyozumi, M; Kojima, S; Shimada, H; Takahashi, Y1
Kiyozumi, M; Kojima, S; Tagawa, Y; Takahashi, Y1
Arimori, S; Ichikawa, Y; Shimizu, H1
Hayashi, M; Matsunaga, K; Mita, S; Okahara, A1
Matsunaga, K; Mita, S1
Hayashi, M; Iso, T; Kasamatsu, S; Nakata, K; Sasano, M; Suda, H; Yamauchi, H1
Ishikawa, K; Sakaguchi, M1
Abe, C; Hayashi, M; Iso, T; Nozawa, RT; Shiokawa, Y; Yokota, T1
Fujimura, K; Hikida, M; Horiuchi, M; Iso, T; Kuwano, M; Morikawa, K; Uemura, O; Yamauchi, H1
Ohmori, H; Okimura, T; Yamamoto, I1
Brooks, P; Conaghan, PG1
Brooks, P; Conaghan, PG; Girgis, L1
Hirohata, S; Lipsky, PE2
Akamatsu, T; Matsubara, T; Mizuno, K; Saegusa, Y1
Hirohata, S; Inoue, T; Ito, K; Iwamoto, S; Kawashima, C; Kisaki, T; Nishioka, Y; Sawada, T; Shinohara, S; Tohma, S1
Adachi, K; Aoki, T; Hara, J; Kitano, A; Kobayashi, K; Matsumoto, T; Nakamura, S; Obata, A; Obayashi, M; Okabe, H; Okawa, K; Oshitani, N; Suzuki, N; Tabata, A; Watanabe, Y; Yasuda, K1
Kim, HA; Song, YW1
Kubo, T; Matsuno, H; Matsuura, K; Muraguchi, A; Nezuka, T; Sugiyama, E; Tsuji, H1
Kumagai, S; Morinobu, A; Wang, Z1
Aono, H; Horiuchi, M; Matsuoka, H; Mita, S; Nishimura, K; Takai, M; Tsuji, F1
Hirata, D; Iwamoto, M; Kamimura, T; Kano, S; Masuyama, JI; Mimori, A; Minota, S; Okazaki, H; Sato, H; Yoshio, T1
Fukushima, K; Inoue, T; Takeshita, K1
Inoue, T; Nakaike, S; Sugimoto, M; Takeshita, K; Yamashita, M1
Ohno, I1
Aoyama, M; Asai, K; Fukuoka, M; Kobayashi, M; Kusabe, T; Otsuka, T; Tanikawa, T; Waguri-Nagaya, Y1
Berezné, A; Guillevin, L; Mouthon, L; Poiraudeau, S1
Akizawa, T; Koshikawa, S; Kuroki, A1
Mimori, T; Yukawa, N1
Baňasová, M; Hrabárová, E; Juránek, I; Nagy, M; Priesolová, E; Soltés, L; Valachová, K1
Aryanian, Z; Daneshpazhooh, M; Etesami, I; Ghaedi, F; Goodarzi, A; Kalantari, Y; Mahmoudi, H; Tavakolpour, S; Teymourpour, A1

Reviews

8 review(s) available for penicillamine and bucillamine

ArticleYear
"Yellow nail syndrome" and rheumatoid arthritis.
    The Tokai journal of experimental and clinical medicine, 1991, Volume: 16, Issue:5-6

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Middle Aged; Nail Diseases; Nails; Penicillamine; Syndrome

1991
Disease-modifying antirheumatic drugs, including methotrexate, gold, antimalarials, and D-penicillamine.
    Current opinion in rheumatology, 1995, Volume: 7, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Drug Therapy, Combination; Gold; Humans; Methotrexate; Penicillamine; Sulfasalazine

1995
Disease-modifying antirheumatic drugs, including methotrexate, sulfasalazine, gold, antimalarials, and penicillamine.
    Current opinion in rheumatology, 1994, Volume: 6, Issue:3

    Topics: Age Factors; Antimalarials; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Digestive System; Gold; Humans; Liver; Methotrexate; Penicillamine; Sulfasalazine

1994
[Drug induced nephrotic syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62, Issue:10

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Antirheumatic Agents; Cysteine; Humans; Nephrotic Syndrome; Organogold Compounds; Penicillamine

2004
[Therapeutic management of systemic sclerosis].
    Presse medicale (Paris, France : 1983), 2006, Volume: 35, Issue:12 Pt 2

    Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Cyclophosphamide; Cysteine; Epoprostenol; Humans; Hypertension, Pulmonary; Immunosuppressive Agents; Interferons; Lung Diseases, Interstitial; Orthotic Devices; Penicillamine; Peripheral Blood Stem Cell Transplantation; Physical Therapy Modalities; Prospective Studies; Randomized Controlled Trials as Topic; Retrospective Studies; Scleroderma, Systemic; Vasodilator Agents

2006
[Drug-induced nephrotic syndrome].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Antineoplastic Agents; Antirheumatic Agents; Bone Density Conservation Agents; Cysteine; Diphosphonates; Gold Compounds; Humans; Interferons; Lithium Compounds; Nephrotic Syndrome; Pamidronate; Penicillamine

2007
[Effect of disease modifying anti-rheumatic drugs on radiographic progression in rheumatoid arthritis].
    Clinical calcium, 2009, Volume: 19, Issue:3

    Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Cysteine; Disease Progression; Drug Therapy, Combination; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Methotrexate; Penicillamine; Radiography; Randomized Controlled Trials as Topic; Sulfasalazine; Tacrolimus

2009
Drug-induced pemphigus: A systematic review of 170 patients.
    International immunopharmacology, 2021, Volume: 92

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Antirheumatic Agents; Captopril; Cysteine; Drug-Related Side Effects and Adverse Reactions; Humans; Pemphigus; Penicillamine

2021

Trials

2 trial(s) available for penicillamine and bucillamine

ArticleYear
SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) in rheumatoid arthritis.
    Scandinavian journal of rheumatology, 1986, Volume: 15, Issue:1

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteine; Drug Eruptions; Elasticity; Female; Gold; Humans; Middle Aged; Penicillamine; Tensile Strength; Time Factors

1986
A comparison between bucillamine and D-penicillamine in the treatment of rheumatoid arthritis.
    Rheumatology international, 1997, Volume: 17, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Middle Aged; Penicillamine

1997

Other Studies

21 other study(ies) available for penicillamine and bucillamine

ArticleYear
Characterization of gold in urine and bile following administration of gold sodium thiomalate with chelating agents to rats.
    Toxicology, 1992, Volume: 74, Issue:1

    Topics: Animals; Bile; Chelating Agents; Chromatography; Cysteine; Electrophoresis; Gold; Gold Sodium Thiomalate; Injections, Intravenous; Male; Penicillamine; Rats; Rats, Inbred Strains; Succimer; Unithiol

1992
Protective effects of chelating agents against renal toxicity of gold sodium thiomalate in rats.
    Archives of toxicology, 1991, Volume: 65, Issue:7

    Topics: Animals; Chelating Agents; Cysteine; Glycosuria; Gold Sodium Thiomalate; Kidney Diseases; Male; Penicillamine; Rats; Rats, Inbred Strains; Succimer; Unithiol

1991
Effect of bucillamine (SA96) on type II collagen induced arthritis in rats.
    The Journal of rheumatology, 1991, Volume: 18, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cell Division; Collagen; Cysteine; Dose-Response Relationship, Drug; Indomethacin; Male; Penicillamine; Rats; Synovial Membrane

1991
Differences in the effects of the antirheumatic drugs, bucillamine and D-penicillamine, on mitogen-induced proliferation of mouse spleen cells.
    Agents and actions, 1990, Volume: 30, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Catalase; Cell Division; Cells, Cultured; Concanavalin A; Copper; Cysteine; Male; Mice; Mice, Inbred C3H; Penicillamine; Spleen; Structure-Activity Relationship

1990
[Pharmacological studies on N-(2-mercapto-2-methylpropanoyl)-L-cysteine(SA96). IV. Effects of SA96 and its main metabolite, SA679, on denaturation of human gamma-globulin and adjuvant arthritis in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 85, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Arthritis, Experimental; Cysteine; gamma-Globulins; Indomethacin; Male; Organ Size; Penicillamine; Protein Denaturation; Rats; Rats, Inbred Lew; Serum Albumin, Bovine

1985
Effects of immunomodulators on candidacidal activity of normal peritoneal cells in BALB/c mice.
    International journal of immunopharmacology, 1986, Volume: 8, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Candidiasis; Cysteine; Female; Hydrocortisone; Levamisole; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Penicillamine

1986
[Pharmacological studies of N-(2-mercapto-2-methylpropionyl)-L-cysteine (SA 96). VI. Effects on vitamin B6, metals and skin collagen in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1985, Volume: 86, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Body Weight; Collagen; Cysteine; Liver; Male; Metals; Penicillamine; Pyridoxine; Rats; Rats, Inbred Strains; Skin

1985
SA96: an immunopharmacological profile in vitro.
    International journal of tissue reactions, 1982, Volume: 4, Issue:1

    Topics: Animals; Antibody Formation; Antibody-Producing Cells; Cattle; Concanavalin A; Cysteine; Dose-Response Relationship, Drug; Female; Fetal Blood; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Mercaptoethanol; Mice; Mice, Inbred BALB C; Penicillamine; Spleen

1982
Comparative inhibitory effects of bucillamine and D-penicillamine on the function of human B cells and T cells.
    Arthritis and rheumatism, 1994, Volume: 37, Issue:6

    Topics: Adult; B-Lymphocytes; Cysteine; Humans; Immunoglobulin M; Interferon-gamma; Interleukin-6; Penicillamine; T-Lymphocytes

1994
Inhibition of mitogen-induced response of human peripheral blood mononuclear cells by bucillamine, a new antirheumatic sulfhydryl drug.
    Rheumatology international, 1994, Volume: 13, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Copper; Copper Sulfate; Cysteine; DNA; Humans; Hydrogen Peroxide; Leukocytes, Mononuclear; Mitogens; Penicillamine; Phytohemagglutinins

1994
[Analysis of the state of patients with rheumatoid arthritis using a personal computer].
    Ryumachi. [Rheumatism], 1993, Volume: 33, Issue:2

    Topics: Age Factors; Arthritis, Rheumatoid; Cysteine; Databases, Factual; Female; Gold Sodium Thiomalate; Humans; Male; Microcomputers; Middle Aged; Penicillamine; Quality of Life; Time Factors

1993
Regulation of B cell function by bucillamine, a novel disease-modifying antirheumatic drug.
    Clinical immunology and immunopathology, 1993, Volume: 66, Issue:1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; B-Lymphocytes; Copper; Cysteine; Depression, Chemical; Humans; Immunoglobulin M; Lymphocyte Activation; Penicillamine

1993
Effect of bucillamine on the rat trinitrobenzene sulfonic acid induced model of colitis.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1996, Volume: 45, Issue:10

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Colitis; Cysteine; Male; Penicillamine; Rats; Rats, Wistar; Trinitrobenzenes

1996
Pharmacological effects of SA96 (bucillamine) and its metabolites as immunomodulating drugs--the disulfide structure of SA-96 metabolites plays a critical role in the pharmacological action of the drug.
    International journal of immunopharmacology, 1998, Volume: 20, Issue:6

    Topics: Adjuvants, Immunologic; Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cells, Cultured; Cysteine; Disulfides; Female; Gas Chromatography-Mass Spectrometry; Humans; Interleukin-6; Interleukin-8; Male; Middle Aged; Penicillamine; Rats; Structure-Activity Relationship; Synovial Fluid

1998
Bucillamine suppresses human Th1 cell development by a hydrogen peroxide-independent mechanism.
    The Journal of rheumatology, 2000, Volume: 27, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Cysteine; Flow Cytometry; Humans; Hydrogen Peroxide; Interferon-gamma; Interleukin-12; Interleukin-2; Interleukin-4; Leukocyte Common Antigens; Oxidants; Penicillamine; Th1 Cells

2000
Effects of sulfhydryl compounds on interleukin-1-induced vascular endothelial growth factor production in human synovial stromal cells.
    Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:5

    Topics: Acetylcysteine; Cells, Cultured; Cysteine; Endothelial Growth Factors; Humans; Interleukin-1; Lymphokines; Penicillamine; Stromal Cells; Sulfhydryl Compounds; Synovial Membrane; Tiopronin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2000
In vitro and in vivo inhibition of activation induced T cell apoptosis by bucillamine.
    The Journal of rheumatology, 2000, Volume: 27, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; B-Lymphocytes; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cysteine; Dexamethasone; Enterotoxins; Flow Cytometry; Glucocorticoids; Hybridomas; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Penicillamine; Reactive Oxygen Species; Superantigens; Thymus Gland

2000
Effects of KE-758; an active metabolite of the new anti-rheumatic drug KE-298, D-penicillamine, bucillamine and auranofin on the proliferation of murine lymphocytes, and the production of nitric oxide by murine macrophages.
    International immunopharmacology, 2001, Volume: 1, Issue:5

    Topics: Animals; Antirheumatic Agents; Auranofin; Cell Division; Cell Line; Concanavalin A; Cysteine; Female; Hydrogen Peroxide; In Vitro Techniques; Interferon-gamma; Ionomycin; Lipopolysaccharides; Lymphocyte Activation; Lymphocytes; Macrophages; Mice; Mice, Inbred DBA; Nitric Oxide; Penicillamine; Phenylpropionates; Recombinant Proteins; Tetradecanoylphorbol Acetate

2001
KE-758, an active metabolite of the new anti-rheumatic drug KE-298, suppresses production of tumor necrosis factor-alpha and interleukin-1 beta in THP-1, a human monocyte cell line.
    Drugs under experimental and clinical research, 2002, Volume: 28, Issue:5

    Topics: Antirheumatic Agents; Auranofin; Cell Line; Cysteine; Enzyme-Linked Immunosorbent Assay; Humans; Interferon-gamma; Interleukin-1; Lipopolysaccharides; Monocytes; Penicillamine; Phenylbutyrates; Phenylpropionates; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha

2002
The inhibitory effect of disease-modifying anti-rheumatic drugs and steroids on gliostatin/platelet-derived endothelial cell growth factor production in human fibroblast-like synoviocytes.
    Rheumatology international, 2005, Volume: 25, Issue:8

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cells; Cells, Cultured; Cysteine; Dexamethasone; Elbow; Female; Fibroblasts; Humans; Knee; Methotrexate; Middle Aged; Organogold Compounds; Orthopedic Procedures; Penicillamine; Phenylacetates; Sulfasalazine; Synovial Membrane; Thymidine Phosphorylase

2005
Free-radical degradation of high-molecular-weight hyaluronan induced by ascorbate plus cupric ions. Testing of bucillamine and its SA981-metabolite as antioxidants.
    Journal of pharmaceutical and biomedical analysis, 2011, Nov-01, Volume: 56, Issue:3

    Topics: Antioxidants; Antirheumatic Agents; Ascorbic Acid; Cations; Copper; Cysteine; Free Radicals; Hyaluronic Acid; Hydroxyl Radical; Molecular Weight; Oxidation-Reduction; Penicillamine; Peroxides; Viscosity

2011