penicillamine and acetylcysteine

penicillamine has been researched along with acetylcysteine in 79 studies

Research

Studies (79)

Timeframe	Studies, this research(%)	All Research%
pre-1990	31 (39.24)	18.7374
1990's	18 (22.78)	18.2507
2000's	15 (18.99)	29.6817
2010's	13 (16.46)	24.3611
2020's	2 (2.53)	2.80

Authors

Authors	Studies
DeMaster, EG; Goon, DJ; Nagasawa, HT	1
Cheng, JP; Wang, K; Wang, PG; Wen, Z; Xian, M; Zhang, W	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Brimacombe, KR; Dulcey, AE; Goldsborough, AS; Gottesman, MM; Griffiths, G; Hall, MD; Handley, MD; Kannan, P; Pluchino, KM	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Kalafatas, P; Kotsifopoulos, P; Vorias, N; Voulgaris, E	1
Johannsen, B; Münze, R; Spies, H; Syhre, R	1
Kotsifopoulos, PN	1
Cederbaum, AI; Rubin, E	1
Abbasi, AH; Cestero, RV; Clarkson, TW; Freeman, RB; Kostyniak, PJ	1
Burkart, V; Kallmann, B; Kolb, H; Kolb-Bachofen, V; Kröncke, KD	1
Chern, WH; Han, BJ; Lee, FW; Shaffer, JE	1
Crumley, RL; Jakowatz, JG; Waki, EY	1
Denneberg, T; Lindell, A; Mårtensson, J; Textorius, O	1
Kerem, D; Lalitha, T; Yannai, S	1
Ignarro, LJ; Wood, KS	1
Drummer, OH; Henry, PJ; Horowitz, JD	1
Bast, A; Haenen, GR; Timmerman, H; Vermeulen, NP	1
Casas, JS; Filella, M; García Bugarín, M; Sordo, J	1
Chang, R; Marshall, FF; Singh, A	1
Mason, RP; Mottley, C; Toy, K	1
Lakin, CA; Oliver, JR; Scott, JS	1
Livingston, GL; Schild, JA	1
Ammon, HP; Enz, G; Hehl, KH; Setiadi-Ranti, A; Verspohl, EJ	1
Christophidis, N; Drummer, OH; Horowitz, JD; Louis, WJ	1
Lewis, PA; Maddock, J; Woodward, AJ	1
Habersang, RW; Hale, TW; Henderson, P; Shum, S	1
Norseth, T	1
Raab, W	1
Hollinger, HZ; Kisil, FT; Sehon, AH	1
Corrocher, R; Cortesi, S; De Sandre, G; Perona, G; Vettore, L	1
Bailey, KR; Sheffner, AL	1
Banner, W; Berlin, M; Clarkson, TW; Lund, ME	1
Brown, DT; Marsh, RR; Wetmore, RF	1
Cavrini, V; Di Pietra, AM; Raggi, MA	1
Gruber, C; Gruber, DK; Lent, R; Levenson, SM; Seifter, E	1
Habersang, R; Shum, S; Skarbovig, J	1
Nagasawa, HT; Zera, RT	1
Biaglow, JE; Held, KD	1
Beyersbergen van Henegouwen, GM; van den Broeke, LT	1
Belal, F; Eid, MM; Rizk, MS	1
Dalal, NS; Kasprzak, KS; Shi, X	1
Lopez Garcia, I; Martinez Gil, JA; Viñas, P	1
Lock, EA	1
Abeles, AJ; Block, ER; Patel, JM	1
Hoener, B; Shen, W	1
Herman, AG; Matthys, KE; Zamora, R	1
Clark, JE; Foresti, R; Green, CJ; Motterlini, R	1
Frölich, JC; Gutzki, FM; Rossa, S; Sandmann, J; Tsikas, D	1
Bonavita, F; Caldarera, CM; Clo, C; Guarnieri, C; Muscari, C; Pignatti, C; Stanic, I; Stefanelli, C; Tantini, B	1
Metodiewa, D; Winterbourn, CC	1
Buhimschi, CS; Buhimschi, IA; Kramer, WB; Thompson, LP; Weiner, CP	1
Bundy, RE; Chester, AH; Marczin, N; Yacoub, M	1
Brecher, P; Cohen, RA; Wang, D; Yu, X	1
Aono, H; Horiuchi, M; Matsuoka, H; Mita, S; Nishimura, K; Takai, M; Tsuji, F	1
Delogu, MR; Desole, MS; Esposito, G; Miele, E; Miele, M; Migheli, R; Rocchitta, G; Serra, PA	1
Brash, DE; Havre, PA; McCormick, JJ; O'Reilly, S	1
COLLINI, WR; HARRIS, RC; MATTERN, SR; SHAPIRO, P; ZINSSER, HH	1
Frost, MC; Meyerhoff, ME	1
Billiar, TR; Kim, PK; McCloskey, C; Vallabhaneni, R; Vodovotz, Y; Zuckerbraun, BS	1
Faundez, V; Love, R; Salazar, G	1
Grünblatt, E; Mandel, S; Youdim, MB	1
Fischer, TH; Schoenfisch, MH; Stasko, NA	1
Joshi, D; Shrivastava, S; Shukla, S; Singh, V	1
Aagaard, NK; Holland-Fischer, P; Jørgensen, SP; Ott, P; Thomsen, KL	1
Guan, D; Shen, Z; Wang, H; Wang, X; Xu, Y; Yang, M	1
Sajewicz, W	1
Myerson, AS; Singh, A	1
Karakosta, TD; Tzanavaras, PD	1
Fan, X; Monnier, VM; Nemet, I; Potts, B; Strauch, CM; Xiaoqin, L	1
Akyildiz, BN; Kondolot, M; Konuşkan, B; Kurtoğlu, S	1
Guo, XF; Tu, FQ; Wang, H; Wang, P; Zhang, HS; Zhang, LY	1
Ali, E; Gul, R; Hussain, A; Jabbar, A; Jan, SU; Khan, MF; Kuthu, ZH; Mukhtiar, M; Ullah, I; Wasim, M	1
Hussain, A; Jan, SU; Khan, MF; Mukhtiar, M; Qureshi, MM; Rehman, S; Ullah, N	1
Chao, MR; Chen, YP; Li, CC; Lin, CP; Liu, KL; Wang, TS	1
Alharthi, NS; Arain, SP; Eltayeb, LB; Khan, H; Mangi, AA; Shaikh, ZA; Siyal, FJ	1
Güven, D; Özbek, İ	1

Reviews

1 review(s) available for penicillamine and acetylcysteine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for penicillamine and acetylcysteine

Article	Year
Letter: Cysteamine for paracetamol overdosage. Lancet (London, England), 1974, May-18, Volume: 1, Issue:7864 Topics: Acetaminophen; Acetylcysteine; Blood Specimen Collection; Chemical and Drug Induced Liver Injury; Chromatography, Gas; Clinical Trials as Topic; Cysteamine; Dimercaprol; Humans; Penicillamine; Poisoning; Time Factors	1974

Other Studies

77 other study(ies) available for penicillamine and acetylcysteine

Article	Year
2,5,5-Trimethylthiazolidine-4-carboxylic acid, a D(-)-penicillamine-directed pseudometabolite of ethanol. Detoxication mechanism for acetaldehyde. Journal of medicinal chemistry, 1978, Volume: 21, Issue:12 Topics: Acetaldehyde; Acetylation; Animals; Ethanol; Inactivation, Metabolic; Male; Methods; Penicillamine; Radioisotope Dilution Technique; Rats; Stereoisomerism; Thiazoles	1978
Equilibrium and kinetics studies of transnitrosation between S-nitrosothiols and thiols. Bioorganic & medicinal chemistry letters, 2001, Feb-12, Volume: 11, Issue:3 Topics: Kinetics; Mercaptoethanol; Nitrosation; Nitroso Compounds; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Serum Albumin, Bovine; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Thermodynamics	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin. Journal of medicinal chemistry, 2011, Jul-28, Volume: 54, Issue:14 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Multidrug Resistance-Associated Proteins; Orphan Drug Production; Paclitaxel; RNA Stability; RNA, Messenger; Structure-Activity Relationship; Tiopronin	2011
Susceptibility to autoxidation of lipids of paroxysmal nocturnal hemoglobinuria (PNH)-like red cells. Acta haematologica, 1977, Volume: 58, Issue:3 Topics: Acetylcysteine; Adolescent; Adult; Erythrocyte Membrane; Erythrocytes; Hemoglobinuria, Paroxysmal; Humans; Membrane Lipids; Oxidation-Reduction; Penicillamine	1977
Chemical and biological characterization of different Tc complexes of cysteine and cysteine derivatives. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1978, Volume: 19, Issue:7 Topics: Acetylcysteine; Animals; Cysteine; Isotope Labeling; Male; Penicillamine; Rats; Technetium; Tissue Distribution	1978
Red cell membrane proteins abnormality in paroxysmal nocturnal hemoglobinuria and in in vitro induced PNH-like erythrocytes. Acta haematologica, 1976, Volume: 56, Issue:6 Topics: Acetylcysteine; Electrophoresis, Starch Gel; Erythrocyte Membrane; Erythrocytes; Hemoglobinuria, Paroxysmal; Humans; Membrane Proteins; Penicillamine	1976
Mechanism of the protective action of cysteine and penicillamine against acetaldehyde-induced mitochondrial injury. Biochemical pharmacology, 1976, Oct-01, Volume: 25, Issue:19 Topics: Acetaldehyde; Acetylcysteine; Animals; Carbon Dioxide; Cysteine; In Vitro Techniques; Mitochondria, Liver; Oxygen Consumption; Penicillamine; Rats; Structure-Activity Relationship; Time Factors	1976
An extracorporeal complexing hemodialysis system for the treatment of methylmercury poisoning. I. In vitro studies of the effects of four complexing agents on the distribution and dialyzability of methylmercury in human blood. The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:2 Topics: Acetates; Acetylcysteine; Blood Proteins; Cysteine; Humans; In Vitro Techniques; Mercury Isotopes; Mercury Poisoning; Methylmercury Compounds; Penicillamine; Protein Binding; Radioisotopes; Renal Dialysis; Sulfhydryl Reagents; Time Factors	1975
Toxicity of chemically generated nitric oxide towards pancreatic islet cells can be prevented by nicotinamide. Life sciences, 1992, Volume: 51, Issue:9 Topics: Acetylcysteine; Animals; Benzamides; Cell Survival; Cells, Cultured; Free Radical Scavengers; In Vitro Techniques; Islets of Langerhans; Kinetics; Niacinamide; Nitric Oxide; Nitroprusside; Penicillamine; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Inbred Strains; S-Nitroso-N-Acetylpenicillamine; Sodium Cyanide; Thioctic Acid; Thiosulfate Sulfurtransferase; Vasodilator Agents	1992
Lack of tolerance to a 24-hour infusion of S-nitroso N-acetylpenicillamine (SNAP) in conscious rabbits. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1 Topics: Acetylcholine; Acetylcysteine; Animals; Body Weight; Consciousness; Dose-Response Relationship, Drug; Drug Tolerance; Erythrocyte Aggregation; Hematocrit; Hemodynamics; Male; Nitroglycerin; Nitroprusside; Penicillamine; Rabbits; S-Nitroso-N-Acetylpenicillamine; Time Factors; Vasodilator Agents	1992
Effects of pharmacologic agents on human keloids implanted in athymic mice. A pilot study. Archives of otolaryngology--head & neck surgery, 1991, Volume: 117, Issue:10 Topics: Acetylcysteine; Adolescent; Adult; Animals; Colchicine; Female; Humans; Keloid; Male; Mice; Mice, Nude; Penicillamine; Pilot Projects; Triamcinolone Acetonide	1991
Sulfur amino acid metabolism in cystinuria: a biochemical and clinical study of patients. Kidney international, 1990, Volume: 37, Issue:1 Topics: Acetylcysteine; Adult; Amino Acids, Sulfur; Cysteine; Cystinuria; Female; Homozygote; Humans; Male; Penicillamine; Tiopronin	1990
Effect of N-acetyl-cysteine, D-penicillamine and buthionine sulfoximine on glutathione levels and CNS oxygen toxicity in rats. Pharmacology & toxicology, 1990, Volume: 66, Issue:1 Topics: Acetylcysteine; Administration, Oral; Animals; Brain; Buthionine Sulfoximine; Drinking; Electrocardiography; Glutathione; Glutathione Peroxidase; Injections, Intraperitoneal; Male; Methionine Sulfoximine; Penicillamine; Rats; Rats, Inbred Strains	1990
Hepatic cyclic GMP formation is regulated by similar factors that modulate activation of purified hepatic soluble guanylate cyclase. The Journal of biological chemistry, 1987, Apr-15, Volume: 262, Issue:11 Topics: 1-Methyl-3-isobutylxanthine; Acetaminophen; Acetylcysteine; Animals; Cyclic AMP; Cyclic GMP; Guanylate Cyclase; Heme; Liver; Methylnitronitrosoguanidine; Mice; Nitroglycerin; Penicillamine; Phenobarbital; Phenylhydrazines; Potassium Cyanide; Probenecid; Protoporphyrins; Purinones; S-Nitroso-N-Acetylpenicillamine	1987
S-nitrosothiols as vasodilators: implications regarding tolerance to nitric oxide-containing vasodilators. British journal of pharmacology, 1989, Volume: 98, Issue:3 Topics: Acetylcysteine; Animals; Ascorbic Acid; Cattle; Chromatography, High Pressure Liquid; Coronary Vessels; Cystine; Drug Tolerance; In Vitro Techniques; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroglycerin; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents	1989
Effect of thiols on lipid peroxidation in rat liver microsomes. Chemico-biological interactions, 1989, Volume: 71, Issue:2-3 Topics: Acetylcysteine; Animals; Cysteamine; Cysteine; Dithiothreitol; Glutathione; Kinetics; Lipid Peroxidation; Male; Microsomes, Liver; Penicillamine; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Sulfhydryl Compounds	1989
Thallium (I) interactions in biological fluids: a potentiometric investigation of thallium(I) complex equilibria with some sulphur-containing amino acids. Journal of inorganic biochemistry, 1989, Volume: 35, Issue:2 Topics: Acetylcysteine; Amino Acids; Chemical Phenomena; Chemistry; Cysteine; Kinetics; Penicillamine; Potentiometry; Thallium	1989
Cystine calculi: clinical management and in vitro observations. Urology, 1988, Volume: 31, Issue:3 Topics: Acetylcysteine; Adult; Ascorbic Acid; Bicarbonates; Cystine; Cystinuria; Female; Homozygote; Humans; Kidney Calculi; Male; Middle Aged; Penicillamine; Sodium; Sodium Bicarbonate; Tromethamine	1988
Oxidation of thiol drugs and biochemicals by the lactoperoxidase/hydrogen peroxide system. Molecular pharmacology, 1987, Volume: 31, Issue:4 Topics: Acetylcysteine; Captopril; Cysteamine; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Glutathione; Hydrogen Peroxide; Lactoperoxidase; Oxygen Consumption; Penicillamine; Peroxidases; Sulfhydryl Compounds	1987
The effect of cysteamine, cystamine, and the structurally related compounds taurine, N-acetyl-cysteine, and D-penicillamine on plasma prolactin levels in normal and estrogen-primed hyperprolactinemic rats. Endocrinology, 1987, Volume: 121, Issue:2 Topics: Acetylcysteine; Animals; Cystamine; Cysteamine; Estradiol; Hyperprolactinemia; Male; Metoclopramide; Penicillamine; Prolactin; Rats; Taurine; Thyrotropin-Releasing Hormone	1987
Lathyrogenic agents as therapy for subglottic stenosis--a pilot study. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1987, Volume: 97, Issue:5 Topics: Acetylcysteine; Animals; Cicatrix; Collagen; Combined Modality Therapy; Disease Models, Animal; Dogs; Laryngostenosis; Laser Therapy; Penicillamine	1987
Cysteine analogues potentiate glucose-induced insulin release in vitro. Diabetes, 1986, Volume: 35, Issue:12 Topics: Acetylcysteine; Animals; Cysteamine; Cysteine; Dose-Response Relationship, Drug; Female; Glucose; Glutathione; Insulin; Insulin Secretion; Islets of Langerhans; Male; Penicillamine; Rats; Rats, Inbred Strains; Structure-Activity Relationship	1986
Measurement of penicillamine and N-acetylcysteine in human blood by high-performance liquid chromatography and electrochemical detection. Journal of chromatography, 1986, Jan-24, Volume: 374, Issue:2 Topics: Acetylcysteine; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Drug Stability; Electrochemistry; Humans; Kinetics; Penicillamine; Sulfhydryl Compounds	1986
Improved method for the determination of N-acetylcysteine in human plasma by high-performance liquid chromatography. Journal of chromatography, 1985, Jun-26, Volume: 327 Topics: Acetylcysteine; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Dinitrofluorobenzene; Humans; Penicillamine	1985
N-Acetylcysteine therapy of acute heavy metal poisoning in mice. Veterinary and human toxicology, 1985, Volume: 27, Issue:6 Topics: Acetylcysteine; Acute Disease; Animals; Dimercaprol; Metals; Mice; Penicillamine	1985
The effect of chelating agents on biliary excretion of methyl mercuric salts in the rat. Acta pharmacologica et toxicologica, 1973, Volume: 32, Issue:1 Topics: Acetamides; Acetylcysteine; Animals; Bile; Bile Ducts; Chelating Agents; Dimercaprol; Female; Injections, Intraperitoneal; Injections, Intravenous; Male; Mercury; Methylmercury Compounds; Organometallic Compounds; Penicillamine; Rats; Sex Factors; Stimulation, Chemical; Time Factors	1973
[The action of D-penicillamine (dimethylcysteine) on human dermal proteins; a comparison with acetylcysteine (author's transl)]. Archiv fur dermatologische Forschung, 1974, Feb-20, Volume: 248, Issue:4 Topics: Acetylcysteine; Cadaver; Humans; Hydroxyproline; In Vitro Techniques; Penicillamine; Proteins; Skin; Time Factors	1974
In vitro and in vivo inactivation of reagins with mercaptans. Clinical allergy, 1971, Volume: 1, Issue:4 Topics: Acetylcysteine; Animals; Antigen-Antibody Complex; Cysteamine; Cysteine; Desensitization, Immunologic; Haplorhini; Humans; Immunoglobulin E; Macaca; Mercaptoethanol; Passive Cutaneous Anaphylaxis; Penicillamine; Rhinitis, Allergic, Seasonal; Sulfhydryl Compounds	1971
Ham-positive red cells induced in vitro by N-acetylcysteine or D-penicillamine. British journal of haematology, 1968, Volume: 15, Issue:5 Topics: Acetylcholinesterase; Acetylcysteine; beta-Aminoethyl Isothiourea; Cysteine; Erythrocytes; Hemolysis; Humans; In Vitro Techniques; Penicillamine	1968
The reduction of experimentally induced inflammation by sulfhydryl compounds. Biochemical pharmacology, 1967, Jul-07, Volume: 16, Issue:7 Topics: Acetylcysteine; Animals; Dexamethasone; Drug Synergism; Hydrocortisone; Inflammation; Male; Methionine; Penicillamine; Rabbits; Salicylates	1967
Treatment of acute methylmercury ingestion by hemodialysis with N-acetylcysteine (Mucomyst) infusion and 2,3-dimercaptopropane sulfonate. Journal of toxicology. Clinical toxicology, 1984, Volume: 22, Issue:1 Topics: Acetylcysteine; Administration, Oral; Adult; Benztropine; Haloperidol; Humans; Kinetics; Male; Mercury; Methylmercury Compounds; Penicillamine; Renal Dialysis; Suicide, Attempted; Unithiol	1984
The action of mucolytic agents on respiratory mucins and the implications for secretory otitis media. Transactions - Pennsylvania Academy of Ophthalmology and Otolaryngology, 1982,Fall, Volume: 35, Issue:2 Topics: Acetylcysteine; Adolescent; Animals; Child; Dithiothreitol; Dogs; Expectorants; Humans; In Vitro Techniques; Infant; Male; Mucins; Otitis Media; Otitis Media with Effusion; Penicillamine; Viscosity	1982
Colorimetric determination of acetylcysteine, penicillamine, and mercaptopropionylglycine in pharmaceutical dosage forms. Journal of pharmaceutical sciences, 1982, Volume: 71, Issue:12 Topics: Acetylcysteine; Amino Acids, Sulfur; Capsules; Colorimetry; Penicillamine; Solutions; Spectrophotometry; Tablets; Tiopronin	1982
Chemical debridement of burns: mercaptans. The Journal of trauma, 1981, Volume: 21, Issue:8 Topics: Acetylcysteine; Animals; Bromelains; Burns; Cysteine; Debridement; Drug Evaluation, Preclinical; Humans; Male; Mercaptoethanol; Penicillamine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Swine	1981
Acute lethal arsenite poisoning in mice: effect of treatment with N-acetylcysteine, D-penicillamine and dimercaprol on survival time. Veterinary and human toxicology, 1981, Volume: 23, Issue:Suppl 1 Topics: Acetylcysteine; Animals; Arsenic Poisoning; Dimercaprol; Dose-Response Relationship, Drug; Mice; Penicillamine; Time Factors	1981
N-Acetyl-DL-penicillamine and acetaminophen toxicity in mice. Journal of pharmaceutical sciences, 1980, Volume: 69, Issue:9 Topics: Acetaminophen; Acetylcysteine; Animals; Chemical and Drug Induced Liver Injury; Male; Mice; Necrosis; Penicillamine	1980
Mechanisms for the oxygen radical-mediated toxicity of various thiol-containing compounds in cultured mammalian cells. Radiation research, 1994, Volume: 139, Issue:1 Topics: Acetylcysteine; Animals; Cell Line; Cell Survival; Copper; Cricetinae; Cricetulus; Dithiothreitol; Dose-Response Relationship, Drug; Glutathione; Hydrogen Peroxide; Kinetics; Lung; Mercaptoethylamines; Oxidation-Reduction; Penicillamine; Radiation-Protective Agents; Sulfhydryl Compounds; Superoxides	1994
UV-radiation protecting efficacy of thiols, studied with UVA-induced binding of 8-MOP and CPZ to rat epidermal biomacromolecules in vivo. International journal of radiation biology, 1993, Volume: 63, Issue:4 Topics: Acetylcysteine; Animals; Captopril; Chlorpromazine; Cysteamine; Epidermis; Ergothioneine; Female; Mesna; Methoxsalen; Penicillamine; Radiation-Protective Agents; Rats; Rats, Wistar; Sulfhydryl Compounds; Tiopronin; Ultraviolet Rays	1993
Conductometric determination of some pharmaceutically important thiol compounds in dosage forms. Acta pharmaceutica Hungarica, 1993, Volume: 63, Issue:6 Topics: Acetylcysteine; Capsules; Captopril; Electrochemistry; Mercaptopurine; Penicillamine; Powders; Sulfhydryl Compounds; Tablets; Thioguanine	1993
Generation of free radicals in reactions of Ni(II)-thiol complexes with molecular oxygen and model lipid hydroperoxides. Journal of inorganic biochemistry, 1993, May-15, Volume: 50, Issue:3 Topics: Acetylcysteine; Benzene Derivatives; Cysteine; Electron Spin Resonance Spectroscopy; Free Radicals; Histidine; Lipid Peroxides; Nickel; Oxygen; Penicillamine; Peroxides; Sulfhydryl Compounds; tert-Butylhydroperoxide	1993
Determination of thiol-containing drugs by chemiluminescence-flow injection analysis. Journal of pharmaceutical and biomedical analysis, 1993, Volume: 11, Issue:1 Topics: Acetylcysteine; Catalysis; Copper; Cysteine; Flow Injection Analysis; Hydrogen Peroxide; Hydrogen-Ion Concentration; Luminescent Measurements; Luminol; Penicillamine; Sulfhydryl Compounds; Tiopronin	1993
Piggy-back race. Human & experimental toxicology, 1995, Volume: 14, Issue:11 Topics: Acetylcysteine; Animals; Binding, Competitive; Brain; Capillaries; Cells, Cultured; Cysteine; Endothelium, Vascular; Glutathione; Homocysteine; Leucine; Methylmercury Compounds; Penicillamine; Stereoisomerism; Sulfhydryl Compounds	1995
Nitric oxide exposure and sulfhydryl modulation alter L-arginine transport in cultured pulmonary artery endothelial cells. Free radical biology & medicine, 1996, Volume: 20, Issue:5 Topics: Acetylcysteine; Acrolein; Animals; Arginine; Biological Transport; Cells, Cultured; Dithiothreitol; Endothelium, Vascular; Ethylmaleimide; L-Lactate Dehydrogenase; Lipid Peroxidation; Nitrates; Nitric Oxide; Nitrites; Penicillamine; Pulmonary Artery; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Compounds; Swine	1996
Mitigation of nitrofurantoin-induced toxicity in the perfused rat liver. Human & experimental toxicology, 1996, Volume: 15, Issue:5 Topics: Acetylcysteine; Adenosine Monophosphate; Animals; Anti-Infective Agents, Urinary; Antidotes; Cell Death; Chelating Agents; Dithiothreitol; Egtazic Acid; Free Radical Scavengers; Free Radicals; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Nitrofurantoin; Oxidation-Reduction; Oxidative Stress; Penicillamine; Perfusion; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Sulfobromophthalein; Tiopronin	1996
The protective role of thiols against nitric oxide-mediated cytotoxicity in murine macrophage J774 cells. European journal of pharmacology, 1997, Feb-19, Volume: 321, Issue:1 Topics: Acetylcysteine; Animals; Benzoates; Buthionine Sulfoximine; Cell Line; Cell Survival; Enzyme Inhibitors; Glutathione; Hydroxylamine; Hydroxylamines; Imidazoles; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase; Sulfhydryl Compounds	1997
Thiol compounds interact with nitric oxide in regulating heme oxygenase-1 induction in endothelial cells. Involvement of superoxide and peroxynitrite anions. The Journal of biological chemistry, 1997, Jul-18, Volume: 272, Issue:29 Topics: Acetylcysteine; Animals; Aorta; Buthionine Sulfoximine; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Induction; Glutathione; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Kinetics; Membrane Proteins; Nitrates; Nitric Oxide; Nitrites; Nitroprusside; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Compounds; Superoxides; Umbilical Veins	1997
Investigations of S-transnitrosylation reactions between low- and high-molecular-weight S-nitroso compounds and their thiols by high-performance liquid chromatography and gas chromatography-mass spectrometry. Analytical biochemistry, 1999, Jun-01, Volume: 270, Issue:2 Topics: Acetylcysteine; Chromatography, High Pressure Liquid; Cysteine; Erythrocytes; Gas Chromatography-Mass Spectrometry; Glutathione; Homocysteine; Humans; Hydroxylamine; In Vitro Techniques; Kinetics; Molecular Weight; Nitric Oxide; Nitroso Compounds; Penicillamine; S-Nitroso-N-Acetylpenicillamine; S-Nitrosothiols; Sulfhydryl Compounds	1999
Nitric oxide can function as either a killer molecule or an antiapoptotic effector in cardiomyocytes. Biochimica et biophysica acta, 1999, Jul-08, Volume: 1450, Issue:3 Topics: Acetylcysteine; Animals; Apoptosis; Caspase Inhibitors; Cells, Cultured; Chick Embryo; Glutathione; Heart; Nitric Oxide; Nitro Compounds; Penicillamine; Staurosporine	1999
Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide. Free radical biology & medicine, 1999, Volume: 27, Issue:3-4 Topics: Acetylcysteine; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cysteamine; Cysteine; Dithiothreitol; Glutathione; Hydrogen Peroxide; Oxygen Consumption; Penicillamine; Reactive Oxygen Species; Sulfhydryl Compounds; Superoxides; Xanthine Oxidase	1999
Reduction-oxidation (redox) state regulation of matrix metalloproteinase activity in human fetal membranes. American journal of obstetrics and gynecology, 2000, Volume: 182, Issue:2 Topics: Acetylcysteine; Cesarean Section; Culture Media, Conditioned; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Extraembryonic Membranes; Female; Free Radical Scavengers; Humans; Image Processing, Computer-Assisted; Lipopolysaccharides; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Nitric Oxide Donors; Nitroarginine; Oxidation-Reduction; Penicillamine; Pregnancy; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Xanthine; Xanthine Oxidase	2000
A redox-based mechanism for nitric oxide-induced inhibition of DNA synthesis in human vascular smooth muscle cells. British journal of pharmacology, 2000, Volume: 129, Issue:7 Topics: Acetylcysteine; Animals; Ascorbic Acid; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Free Radical Scavengers; G1 Phase; Glutathione; Humans; Hydroxyurea; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Oxidation-Reduction; Penicillamine; Rats; S Phase; S-Nitrosoglutathione	2000
Distinct effects of N-acetylcysteine and nitric oxide on angiotensin II-induced epidermal growth factor receptor phosphorylation and intracellular Ca(2+) levels. The Journal of biological chemistry, 2000, Apr-21, Volume: 275, Issue:16 Topics: Acetylcysteine; Angiotensin II; Animals; Calcium; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Heart; Inositol 1,4,5-Trisphosphate; Myocardium; Nitric Oxide; Nitric Oxide Donors; Oxidative Stress; Penicillamine; Phosphorylation; Rats; Transcriptional Activation	2000
Effects of sulfhydryl compounds on interleukin-1-induced vascular endothelial growth factor production in human synovial stromal cells. Biological & pharmaceutical bulletin, 2000, Volume: 23, Issue:5 Topics: Acetylcysteine; Cells, Cultured; Cysteine; Endothelial Growth Factors; Humans; Interleukin-1; Lymphokines; Penicillamine; Stromal Cells; Sulfhydryl Compounds; Synovial Membrane; Tiopronin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2000
Analysis of S-nitroso-N-acetylpenicillamine effects on dopamine release in the striatum of freely moving rats: role of endogenous ascorbic acid and oxidative stress. British journal of pharmacology, 2001, Volume: 132, Issue:4 Topics: Acetylcysteine; Animals; Ascorbic Acid; Corpus Striatum; Dopamine; Iron; Male; Microdialysis; Nitric Oxide Donors; Oxidative Stress; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine	2001
Transformed and tumor-derived human cells exhibit preferential sensitivity to the thiol antioxidants, N-acetyl cysteine and penicillamine. Cancer research, 2002, Mar-01, Volume: 62, Issue:5 Topics: Acetylcysteine; Antioxidants; Apoptosis; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Genes, myc; Humans; Neoplasms; Penicillamine; Tumor Suppressor Protein p53	2002
METHODS OF DIMINISHING CYSTINE EXCRETION IN CYSTINURIA. The Journal of urology, 1965, Volume: 93 Topics: Acetylcysteine; Amino Acids; Cysteine; Cystine; Cystinuria; Diet; Diet Therapy; Drug Therapy; Fluids and Secretions; Indoles; Oxandrolone; Penicillamine; Rats; Sulfur; Vitamin B 6 Deficiency	1965
Synthesis, characterization, and controlled nitric oxide release from S-nitrosothiol-derivatized fumed silica polymer filler particles. Journal of biomedical materials research. Part A, 2005, Mar-15, Volume: 72, Issue:4 Topics: Acetylcysteine; Biocompatible Materials; Copper; Cysteine; Nitric Oxide; Nitric Oxide Donors; Particle Size; Penicillamine; Photochemistry; Platelet Aggregation Inhibitors; Polymers; S-Nitrosothiols; Silicon Dioxide	2005
Hypoxia renders hepatocytes susceptible to cell death by nitric oxide. Cellular and molecular biology (Noisy-le-Grand, France), 2005, Sep-05, Volume: 51, Issue:3 Topics: Acetylcysteine; Adenosine Triphosphate; Animals; Apoptosis; Cell Hypoxia; Cells, Cultured; Hepatocytes; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Donors; Oxidation-Reduction; Oxidative Stress; Penicillamine; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury	2005
Neuronal zinc stores are modulated by non-steroidal anti-inflammatory drugs: an optical analysis in cultured hippocampal neurons. Brain research, 2005, Nov-02, Volume: 1061, Issue:1 Topics: Acetylcysteine; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Chelating Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Ethylenediamines; Flow Cytometry; Fluorescent Dyes; Hippocampus; Macrolides; Microscopy, Confocal; Neurons; Niflumic Acid; Penicillamine; Quinolones; Rats; Sulfides; Temperature; Time Factors; Tosyl Compounds; Zinc; Zinc Oxide	2005
The copper chelator, D-penicillamine, does not attenuate MPTP induced dopamine depletion in mice. Journal of neural transmission (Vienna, Austria : 1996), 2007, Volume: 114, Issue:2 Topics: Acetylcysteine; Animals; Chelating Agents; Chromatography, High Pressure Liquid; Corpus Striatum; Dopamine; Dopamine Agents; Iron; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Nerve Degeneration; Neuroprotective Agents; Penicillamine; Salicylic Acid	2007
S-nitrosothiol-modified dendrimers as nitric oxide delivery vehicles. Biomacromolecules, 2008, Volume: 9, Issue:3 Topics: Acetylcysteine; Copper; Delayed-Action Preparations; Dendrimers; Humans; Light; Nitric Oxide; Nitric Oxide Donors; Nylons; Penicillamine; Pharmaceutical Vehicles; Platelet Aggregation; S-Nitrosothiols	2008
Effect of monothiol along with antioxidant against mercury-induced oxidative stress in rat. Indian journal of experimental biology, 2007, Volume: 45, Issue:12 Topics: Acetylcysteine; Animals; Antioxidants; Chelating Agents; Chemical and Drug Induced Liver Injury; Dietary Supplements; Drug Therapy, Combination; Liver Diseases; Magnesium; Male; Mercury Poisoning; Oxidative Stress; Penicillamine; Rats; Rats, Sprague-Dawley; Sodium Selenite; Treatment Outcome; Zinc	2007
A 15-year-old girl with severe hemolytic Wilson's crisis recovered without transplantation after extracorporeal circulation with the Prometheus system. Blood purification, 2009, Volume: 28, Issue:2 Topics: Acetylcysteine; Adolescent; Antidotes; Copper; Extracorporeal Circulation; Female; Free Radical Scavengers; Hemolysis; Hepatolenticular Degeneration; Humans; Liver; Penicillamine; Serum Albumin; Severity of Illness Index	2009
N-acetyl cysteine and penicillamine induce apoptosis via the ER stress response-signaling pathway. Molecular carcinogenesis, 2010, Volume: 49, Issue:1 Topics: Acetylcysteine; Activating Transcription Factor 4; Activating Transcription Factor 6; Apoptosis; Blotting, Western; DNA-Binding Proteins; eIF-2 Kinase; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Flow Cytometry; Heat-Shock Proteins; HeLa Cells; Humans; Penicillamine; Regulatory Factor X Transcription Factors; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Transcription Factor CHOP; Transcription Factors; X-Box Binding Protein 1	2010
Effect of thiol drugs on tert-butyl hydroperoxide induced luminol chemiluminescence in human erythrocytes, erythrocyte lysate, and erythrocyte membranes. Chemico-biological interactions, 2010, Jul-30, Volume: 186, Issue:2 Topics: Acetylcysteine; Erythrocyte Membrane; Erythrocytes; Humans; In Vitro Techniques; Kinetics; Luminescence; Luminol; Mesna; Models, Biological; Oxidative Stress; Penicillamine; Sulfhydryl Compounds; tert-Butylhydroperoxide; Tiopronin	2010
Chiral self assembled monolayers as resolving auxiliaries in the crystallization of valine. Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:9 Topics: Acetylcysteine; Crystallization; Cysteine; Glutathione; Gold; Penicillamine; Solubility; Stereoisomerism; Valine	2010
Automated tagging of pharmaceutically active thiols under flow conditions using monobromobimane. Journal of pharmaceutical and biomedical analysis, 2011, Mar-25, Volume: 54, Issue:4 Topics: Acetylcysteine; Analytic Sample Preparation Methods; Automation, Laboratory; Bridged Bicyclo Compounds; Captopril; Drug Stability; Fluorescent Dyes; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Limit of Detection; Penicillamine; Quality Control; Reproducibility of Results; Spectrometry, Fluorescence; Sulfhydryl Compounds; Sulfhydryl Reagents; Technology, Pharmaceutical	2011
Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice. Molecular vision, 2011, Volume: 17 Topics: Acetylcysteine; Administration, Topical; Aging; Animals; Arginine; Ascorbic Acid; Biological Transport, Active; Cataract; Crystallins; Gene Knock-In Techniques; Glycation End Products, Advanced; Guanidines; Humans; Lens, Crystalline; Mass Spectrometry; Mice; Mice, Transgenic; Ophthalmic Solutions; Penicillamine; Rabbits; Sodium-Coupled Vitamin C Transporters; Spectrometry, Fluorescence	2011
Case series of mercury toxicity among children in a hot, closed environment. Pediatric emergency care, 2012, Volume: 28, Issue:3 Topics: Accidents; Acetylcysteine; Adolescent; Chelating Agents; Child; Decontamination; Environment; Environmental Exposure; Female; Free Radical Scavengers; Hot Temperature; Humans; Male; Mercury; Mercury Poisoning; Penicillamine; Schools; Thermometers; Turkey	2012
A new BODIPY-based long-wavelength fluorescent probe for chromatographic analysis of low-molecular-weight thiols. Analytical and bioanalytical chemistry, 2014, Volume: 406, Issue:26 Topics: Acetylcysteine; Animals; Boron Compounds; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Cysteine; Dipeptides; Fluorescent Dyes; Glutathione; Homocysteine; Iodoacetamide; Limit of Detection; Male; Mice; Penicillamine; Sulfhydryl Compounds	2014
The role of Glutathione, Cysteine and D-Penicillamine in exchanging Palladium and Vanadium metals from albumin metal complex. Pakistan journal of pharmaceutical sciences, 2017, Volume: 30, Issue:6(Suppleme Topics: Acetylcysteine; Binding Sites; Chelating Agents; Coordination Complexes; Glutathione; Oxidation-Reduction; Palladium; Penicillamine; Protein Binding; Serum Albumin, Bovine; Sulfhydryl Compounds; Vanadium	2017
Report: Palladium glutathione, N-acetylcysteine, D-penicillamine conjugation chemistry. Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:1 Topics: Acetylcysteine; Glutathione; Oxidation-Reduction; Palladium; Penicillamine; Solutions; Vanadium	2018
CYP450-mediated mitochondrial ROS production involved in arecoline N-oxide-induced oxidative damage in liver cell lines. Environmental toxicology, 2018, Volume: 33, Issue:10 Topics: Acetylcysteine; Animals; Antioxidants; Areca; Arecoline; Cell Line; Chromans; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; DNA Damage; Liver; Mitochondria; Mutagenicity Tests; Oxidative Stress; Penicillamine; Rats; Reactive Oxygen Species; Salmonella	2018
Glutathione, Cysteine, and D-Penicillamine Role in Exchange of Silver Metal from the Albumin Metal Complex. BioMed research international, 2022, Volume: 2022 Topics: Acetylcysteine; Coordination Complexes; Cysteine; Glutathione; Metals; Penicillamine; Serum Albumin, Bovine; Silver Nitrate; Sulfhydryl Compounds	2022
Characteristics, Treatment, and Prognosis of Elemental Mercury Intoxication in Children: A Single-Center Retrospective Study. Pediatric emergency care, 2022, Oct-01, Volume: 38, Issue:10 Topics: Acetylcysteine; Child; Humans; Mercury; Mercury Poisoning; Penicillamine; Prognosis; Retrospective Studies; Succimer; Sulfonic Acids	2022