penicillamine has been researched along with acetaldehyde in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (39.13) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 7 (30.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DeMaster, EG; Goon, DJ; Nagasawa, HT | 1 |
| Alexander, CS; DeMaster, EG; Goon, DJ; Nagasawa, HT | 1 |
| Cederbaum, AI; Rubin, E | 1 |
| Alexander, CS; Constantino, NV; Goon, DJ; Nagasawa, HT | 1 |
| Phillips, SC | 1 |
| Elberling, JE; Nagasawa, HT; Roberts, JC | 1 |
| Suzuki, Y; Yamasaki, K | 1 |
| Nagasawa, HT; Zera, RT | 1 |
| Klemm, WR; Mikeska, JA; Sherry, CJ | 1 |
| Darley-Usmar, VM; Hogg, N; Moncada, S; Wilson, MT | 1 |
| Cronholm, T | 1 |
| Cohen, JF; DeMaster, EG; Elberling, JA; Lin, RC; Nagasawa, HT | 1 |
| Aragon, CM; Font, L; Miquel, M | 3 |
| Aragon, CM; Beltrán, J; Font, L; Hernández, F; Miquel, M; Pozo, OJ; Serrano, E | 1 |
| Abate, P; March, SM; Molina, JC; Spear, NE | 1 |
| Granero, L; Hipólito, L; Martí-Prats, L; Orrico, A; Polache, A; Sánchez-Catalán, MJ; Zornoza, T | 1 |
| Aragon, CM; Baliño, P; Font, L; Ledesma, JC | 1 |
| Aragon, CM; Baliño, P; Tarragon, E | 1 |
| Granero, L; López-Moreno, JA; Martí-Prats, L; Polache, A; Zornoza, T | 1 |
| Acquas, E; Bennardini, F; Carta, A; Peana, AT; Porcheddu, V; Rosas, M | 1 |
| Aragón, CG; Baliño, P; Muriach, M; Romero-Cano, R; Sánchez-Andrés, JV; Valls, V | 1 |
23 other study(ies) available for penicillamine and acetaldehyde
| Article | Year |
|---|---|
2,5,5-Trimethylthiazolidine-4-carboxylic acid, a D(-)-penicillamine-directed pseudometabolite of ethanol. Detoxication mechanism for acetaldehyde.
Topics: Acetaldehyde; Acetylation; Animals; Ethanol; Inactivation, Metabolic; Male; Methods; Penicillamine; Radioisotope Dilution Technique; Rats; Stereoisomerism; Thiazoles | 1978 |
Lowering of ethanol-derived circulating blood acetaldehyde in rats by D-penicillamine.
Topics: Acetaldehyde; Animals; Breath Tests; Cysteine; Cystine; Ethanol; Male; Penicillamine; Rats | 1977 |
Mechanism of the protective action of cysteine and penicillamine against acetaldehyde-induced mitochondrial injury.
Topics: Acetaldehyde; Acetylcysteine; Animals; Carbon Dioxide; Cysteine; In Vitro Techniques; Mitochondria, Liver; Oxygen Consumption; Penicillamine; Rats; Structure-Activity Relationship; Time Factors | 1976 |
Diversion of ethanol metabolism by sulfhydryl amino acids. D-penicillamine-directed excretion of 2,5,5-trimethyl-D-thiazolidine-4-carboxylic acid in the urine of rats after ethanol administration.
Topics: Acetaldehyde; Animals; Cysteine; Ethanol; Male; Penicillamine; Rats; Thiazoles | 1975 |
Cytoprotective value of lysine, penicillamine, and pyridoxal phosphate against the neurotoxicity of acetaldehyde.
Topics: Acetaldehyde; Animals; Brain; Lysine; Male; Penicillamine; Pyridoxal Phosphate; Rats; Rats, Inbred Strains | 1989 |
Beta-substituted cysteines as sequestering agents for ethanol-derived acetaldehyde in vivo.
Topics: Acetaldehyde; Animals; Chemical Phenomena; Chemistry; Cyanamide; Cysteine; Disulfiram; Ethanol; Male; Oxidation-Reduction; Penicillamine; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1987 |
Inhibition of pea diamine oxidase by cycloserine.
Topics: Acetaldehyde; Amine Oxidase (Copper-Containing); Copper; Cycloserine; Fructose; Hydroxylamines; Kinetics; Levulinic Acids; Mannose; Methanol; Oxygen Consumption; Penicillamine; Phenanthrolines; Picolines; Plants; Pyridoxal Phosphate; Pyruvates; Spectrum Analysis; Time Factors | 1968 |
Metabolism of paraldehyde to acetaldehyde by rat liver microsomes.
Topics: Acetaldehyde; Animals; Biotransformation; Chromatography, Thin Layer; Kinetics; Male; Microsomes, Liver; Paraldehyde; Penicillamine; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains | 1981 |
Serial-order analysis of spike trains: ethanol effects on cerebellar neurons, with and without penicillamine.
Topics: Acetaldehyde; Animals; Cerebellum; Electroencephalography; Ethanol; Evoked Potentials; Male; Neurons; Penicillamine; Rats | 1980 |
The oxidation of alpha-tocopherol in human low-density lipoprotein by the simultaneous generation of superoxide and nitric oxide.
Topics: Acetaldehyde; Catalase; Free Radicals; Humans; Hydroxides; Hydroxyl Radical; Lipoproteins, LDL; Molsidomine; Nitric Oxide; Nitrogen Dioxide; Oxidation-Reduction; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase; Superoxides; Thiobarbiturates; Vitamin E; Xanthine Oxidase | 1993 |
Ethanol metabolism in isolated hepatocytes. Effects of methylene blue, cyanamide and penicillamine on the redox state of the bound coenzyme and on the substrate exchange at alcohol dehydrogenase.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Cyanamide; Ethanol; Female; In Vitro Techniques; Liver; Methylene Blue; NAD; Oxidation-Reduction; Penicillamine; Rats; Rats, Sprague-Dawley | 1993 |
N-Terminal dipeptides of D(-)-penicillamine as sequestration agents for acetaldehyde.
Topics: Acetaldehyde; Animals; Cell-Free System; Cells, Cultured; Dipeptides; Ethanol; Liver; Male; Penicillamine; Rats; Rats, Wistar; Structure-Activity Relationship | 2000 |
Prevention of ethanol-induced behavioral stimulation by D-penicillamine: a sequestration agent for acetaldehyde.
Topics: Acetaldehyde; Animals; Depression, Chemical; Dose-Response Relationship, Drug; Ethanol; Exploratory Behavior; Injections, Intraperitoneal; Locomotion; Mice; Motor Activity; Penicillamine | 2005 |
Ethanol-induced conditioned place preference, but not aversion, is blocked by treatment with D -penicillamine, an inactivation agent for acetaldehyde.
Topics: Acetaldehyde; Animals; Cocaine; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Antagonism; Ethanol; Male; Mice; Morphine; Motor Activity; Penicillamine | 2006 |
Voluntary ethanol consumption decreases after the inactivation of central acetaldehyde by d-penicillamine.
Topics: Acetaldehyde; Administration, Oral; Alcohol Drinking; Analysis of Variance; Animals; Central Nervous System Depressants; Dose-Response Relationship, Drug; Drinking Behavior; Drug Antagonism; Ethanol; Injections, Intraventricular; Male; Motor Activity; Penicillamine; Rats; Rats, Long-Evans; Self Administration; Sucrose; Taste | 2006 |
Liquid chromatography/tandem mass spectrometry determination of (4S,2RS)-2,5,5-trimethylthiazolidine-4-carboxylic acid, a stable adduct formed between D-(-)-penicillamine and acetaldehyde (main biological metabolite of ethanol), in plasma, liver and brain
Topics: Acetaldehyde; Animals; Brain; Chromatography, High Pressure Liquid; Drug Combinations; Ethanol; Liver; Organ Specificity; Penicillamine; Rats; Spectrometry, Mass, Electrospray Ionization; Thiazolidines; Tissue Distribution | 2007 |
The role of acetaldehyde in ethanol reinforcement assessed by Pavlovian conditioning in newborn rats.
Topics: Acetaldehyde; Animals; Animals, Newborn; Animals, Suckling; Catalase; Conditioning, Classical; Ethanol; Female; Male; Motivation; Penicillamine; Rats; Rats, Wistar; Reinforcement, Psychology | 2013 |
Efficacy of D-penicillamine, a sequestering acetaldehyde agent, in the prevention of alcohol relapse-like drinking in rats.
Topics: Acetaldehyde; Alcohol Drinking; Alcoholism; Animals; Brain; Chelating Agents; Dose-Response Relationship, Drug; Ethanol; Infusion Pumps, Implantable; Male; Osmotic Pressure; Penicillamine; Rats; Rats, Wistar; Secondary Prevention; Time Factors; Tissue Distribution; Ventral Tegmental Area | 2013 |
Modulation of ethanol-induced conditioned place preference in mice by 3-amino-1,2,4-triazole and D-penicillamine depends on ethanol dose and number of conditioning trials.
Topics: Acetaldehyde; Amitrole; Animals; Brain; Catalase; Conditioning, Classical; Cues; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Penicillamine | 2013 |
Centrally formed acetaldehyde mediates ethanol-induced brain PKA activation.
Topics: Acetaldehyde; Amitrole; Animals; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Ethanol; Male; Mice; Penicillamine; Phosphorylation; Thioctic Acid | 2014 |
Acetaldehyde sequestration by D-penicillamine prevents ethanol relapse-like drinking in rats: evidence from an operant self-administration paradigm.
Topics: Acetaldehyde; Alcohol Drinking; Animals; Chelating Agents; Conditioning, Operant; Ethanol; Male; Penicillamine; Rats; Rats, Wistar; Recurrence; Reproducibility of Results; Self Administration | 2015 |
Role of ethanol-derived acetaldehyde in operant oral self-administration of ethanol in rats.
Topics: Acetaldehyde; Administration, Oral; Alcohol Drinking; Amitrole; Animals; Conditioning, Operant; Cues; Ethanol; Male; Penicillamine; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration | 2015 |
Effects of Acute Ethanol Administration on Brain Oxidative Status: The Role of Acetaldehyde.
Topics: Acetaldehyde; Animals; Brain; Dipeptides; Ethanol; Glutamic Acid; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Glutathione Reductase; Male; Malondialdehyde; Mice; Oxidative Stress; Penicillamine; Protein Carbonylation; Thioctic Acid | 2019 |