penicillamine and 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole

penicillamine has been researched along with 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's13 (50.00)18.2507
2000's13 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baker, JE; Joseph, J; Kalyanaraman, B; Konorev, EA; Tarpey, MM1
Irie, K1
Itoh, T; Kamisaki, Y; Moriwaki, Y1
Ito, M; Kamiya, H; Sakurai, M; Watanabe, M1
Herman, AG; Matthys, KE; Zamora, R1
Hagino, Y; Matsui, S; Nomura, H; Nomura, T; Ohtsuki, M; Sumi-Ichinose, C1
Matsumoto, M; Shida, T; Utoguchi, N; Watanabe, Y1
Byrne, CR; Hanson, PJ1
El-Fakahany, EE; Parsons, AM; Sorman, JL1
Hatori, M; Kamijo, R; Nagumo, M; Sumitani, K; Takizawa, K; Toyoshima, T1
Hatashita, M; Hayashi, S; Kano, E; Kitai, R; Matsumoto, H; Ohnishi, K; Ohnishi, T; Ohtsubo, T; Shioura, H1
Fujikado, T; Hosohata, J; Kawasaki, Y; Tanaka, Y; Tano, Y1
Hanson, PJ; Potter, CL1
Alberici, AC; Benussi, L; Binetti, G; Gasparini, L; Ghidoni, R; Growdon, JH; Moratto, D; Nitsch, RM; Trabucchi, M1
Baumgarten, G; Dibbs, Z; Kalra, D; Mann, DL; Seta, Y; Sivasubramanian, N1
Furukawa, O; Kawauchi, S; Mimaki, H; Sugamoto, S; Takeuchi, K1
Chan, JY; Chan, SH; Wang, LL; Wang, SH1
Beligni, MV; Bethke, PC; Fath, A; Jones, RL; Lamattina, L1
Iida, H; Inoue, N; Ishida, H; Ishikawa, Y; Yuan, Z1
McLean, DL; Sillar, KT1
Attia, M; Fetih, G; Fujita, T; Habib, F; Okada, N; Yamamoto, A1
Hachiro, T; Kawahara, K; Nakajima, T; Nakayama, Y; Yamauchi, Y; Yokokawa, T1
Arce, C; Figueroa, S; González, MP; Martinez-Honduvilla, CJ; Oset-Gasque, MJ1
Badal, S; Brown, PD; Ragoobirsingh, D1
Hong, J; Ishihara, K; Kang, YS; Kim, S; Nakano, Y; Ohuchi, K; Yokomakura, A1
Bird, PS; Seymour, GJ; Sosroseno, W1

Other Studies

26 other study(ies) available for penicillamine and 1,3-dihydroxy-4,4,5,5-tetramethyl-2-(4-carboxyphenyl)tetrahydroimidazole

ArticleYear
Nitronyl nitroxides as probes to study the mechanism of vasodilatory action of nitrovasodilators, nitrone spin traps, and nitroxides: role of nitric oxide.
    Free radical biology & medicine, 1995, Volume: 18, Issue:2

    Topics: Animals; Benzoates; Coronary Circulation; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Imidazoles; Male; Nitric Oxide; Nitrogen Oxides; Nitroprusside; Penicillamine; Pyridines; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Spin Labels; Vasodilation; Vasodilator Agents

1995
[Nitric oxide donors and endogenous nitric oxide induced relaxation in isolated rat duodenum].
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 1995, Volume: 31, Issue:6

    Topics: Animals; Benzoates; Duodenum; Imidazoles; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitroprusside; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents

1995
[cGMP synthesis induced by atrial natriuretic peptide, C-type natriuretic peptide, and nitric oxide in the rat retina].
    Nippon Ganka Gakkai zasshi, 1996, Volume: 100, Issue:3

    Topics: Animals; Atrial Natriuretic Factor; Atropine; Benzoates; Calcimycin; Carbachol; Cyclic GMP; Imidazoles; In Vitro Techniques; Ionophores; Male; Natriuretic Peptide, C-Type; Nitric Oxide; Nitroarginine; Penicillamine; Proteins; Rats; Rats, Wistar; Retina; S-Nitroso-N-Acetylpenicillamine

1996
Inhibition of natural killer cell activity against cytomegalovirus-infected fibroblasts by nitric oxide-releasing agents.
    Cellular immunology, 1996, Nov-25, Volume: 174, Issue:1

    Topics: Benzoates; CD18 Antigens; Cells, Cultured; Cytomegalovirus; Cytotoxicity, Immunologic; Humans; Imidazoles; Interferon-alpha; Killer Cells, Natural; Lymphocyte Function-Associated Antigen-1; Nitric Oxide; Nitroso Compounds; Penicillamine; Pyridines; Receptors, IgG; Receptors, Interleukin-2; S-Nitroso-N-Acetylpenicillamine

1996
The protective role of thiols against nitric oxide-mediated cytotoxicity in murine macrophage J774 cells.
    European journal of pharmacology, 1997, Feb-19, Volume: 321, Issue:1

    Topics: Acetylcysteine; Animals; Benzoates; Buthionine Sulfoximine; Cell Line; Cell Survival; Enzyme Inhibitors; Glutathione; Hydroxylamine; Hydroxylamines; Imidazoles; Interferon-gamma; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Sodium-Potassium-Exchanging ATPase; Sulfhydryl Compounds

1997
Nitric oxide donor NOR 3 inhibits ketogenesis from oleate in isolated rat hepatocytes by a cyclic GMP-independent mechanism.
    Pharmacology & toxicology, 1998, Volume: 82, Issue:1

    Topics: Adenosine Triphosphate; Animals; Benzoates; Calcium; Cells, Cultured; Cyclic GMP; Imidazoles; Lactic Acid; Liver; Male; Molsidomine; Nitric Oxide; Nitro Compounds; Oleic Acid; Penicillamine; Rats; Rats, Wistar; S-Nitroso-N-Acetylpenicillamine; Sodium Nitrite; Vasodilator Agents

1998
Nitric oxide donors enhance rectal absorption of macromolecules in rabbits.
    Pharmaceutical research, 1998, Volume: 15, Issue:6

    Topics: Animals; Area Under Curve; Benzoates; Blood Glucose; Dextrans; Fluorescein-5-isothiocyanate; Imidazoles; Insulin; Intestinal Absorption; Male; Nitric Oxide; Penicillamine; Rabbits

1998
Induction of heat shock protein 72 by a nitric oxide donor in guinea-pig gastric mucosal cells.
    European journal of pharmacology, 1998, Jul-17, Volume: 353, Issue:1

    Topics: Animals; Benzoates; Cell Survival; Cells, Cultured; Dactinomycin; Gastric Mucosa; Guinea Pigs; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Imidazoles; Male; Nitric Oxide; Penicillamine; Protein Synthesis Inhibitors; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Compounds; Time Factors

1998
Regulation of M1 muscarinic receptor-mediated signaling in intact cells by exogenous, but not endogenously produced, nitric oxide.
    Neurochemical research, 1999, Volume: 24, Issue:1

    Topics: Animals; Benzoates; Calcium; Carbachol; CHO Cells; Cricetinae; Enzyme Activation; Feedback; Humans; Imidazoles; Inositol Phosphates; Ionomycin; Kinetics; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitroprusside; Penicillamine; Phosphatidylinositols; Receptor, Muscarinic M1; Receptors, Muscarinic; Recombinant Proteins; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Transfection

1999
Nitric oxide up-regulates the expression of intercellular adhesion molecule-1 on cancer cells.
    Biochemical and biophysical research communications, 1999, Apr-13, Volume: 257, Issue:2

    Topics: Benzoates; Carcinoma, Squamous Cell; Cell Adhesion Molecules; Free Radical Scavengers; Genistein; Humans; Imidazoles; Intercellular Adhesion Molecule-1; Molsidomine; NF-kappa B; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Staurosporine; Tongue Neoplasms; Transcription Factor AP-1; Tumor Cells, Cultured; Up-Regulation

1999
Nitric oxide is an initiator of intercellular signal transduction for stress response after hyperthermia in mutant p53 cells of human glioblastoma.
    Cancer research, 1999, Jul-01, Volume: 59, Issue:13

    Topics: Benzoates; Brain Neoplasms; Cell Division; Coculture Techniques; Genes, p53; Glioblastoma; Guanidines; Heat-Shock Proteins; Hot Temperature; HSP72 Heat-Shock Proteins; Humans; Hyperthermia, Induced; Imidazoles; Kinetics; Mutagenesis; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Signal Transduction; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1999
The effect of nitric oxide on the contractile tone of Müller cells.
    Ophthalmic research, 1999, Volume: 31, Issue:6

    Topics: Animals; Benzoates; Cells, Cultured; Chick Embryo; Imidazoles; Neuroglia; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Retina; S-Nitroso-N-Acetylpenicillamine

1999
Exogenous nitric oxide inhibits apoptosis in guinea pig gastric mucous cells.
    Gut, 2000, Volume: 46, Issue:2

    Topics: Animals; Apoptosis; Benzoates; Caspase 1; Cells, Cultured; Ceramides; Cyclic AMP; Depression, Chemical; DNA Fragmentation; Gastric Mucosa; Guinea Pigs; Imidazoles; In Situ Nick-End Labeling; Male; Nitric Oxide; Nitric Oxide Donors; Penicillamine

2000
Modulation of presenilin-1 processing by nitric oxide during apoptosis induced by serum withdrawal and glucose deprivation.
    Annals of the New York Academy of Sciences, 1999, Volume: 893

    Topics: Alzheimer Disease; Apoptosis; Benzoates; Culture Media, Serum-Free; Cytochrome c Group; Deoxyglucose; Glioma; Glucose; Humans; Hypoglycemia; Imidazoles; Membrane Proteins; Mitochondria; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Penicillamine; Presenilin-1; Protein Processing, Post-Translational; S-Nitroso-N-Acetylpenicillamine; Tumor Cells, Cultured

1999
Nitric oxide provokes tumor necrosis factor-alpha expression in adult feline myocardium through a cGMP-dependent pathway.
    Circulation, 2000, Sep-12, Volume: 102, Issue:11

    Topics: Animals; Benzoates; Cats; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; DNA-Binding Proteins; Electrophoresis; I-kappa B Proteins; Imidazoles; In Vitro Techniques; Myocardium; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxadiazoles; Penicillamine; Phosphorylation; Protein Kinases; Quinoxalines; RNA, Messenger; Thionucleotides; Tumor Necrosis Factor-alpha

2000
Stimulation by nitric oxide of gastric acid secretion in bullfrog fundic mucosa in vitro.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2001, Volume: 52, Issue:1

    Topics: Animals; Arginine; Benzoates; Bucladesine; Cimetidine; Enzyme Inhibitors; Gastric Acid; Gastric Fundus; Gastric Mucosa; Histamine Release; Imidazoles; In Vitro Techniques; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitro Compounds; p-Methoxy-N-methylphenethylamine; Penicillamine; Rana catesbeiana; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase

2001
Differential cardiovascular responses to blockade of nNOS or iNOS in rostral ventrolateral medulla of the rat.
    British journal of pharmacology, 2001, Volume: 133, Issue:4

    Topics: Animals; Benzoates; Blood Pressure; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Imidazoles; Indazoles; Male; Medulla Oblongata; Microinjections; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Penicillamine; Rats; Rats, Sprague-Dawley; RNA, Messenger

2001
Nitric oxide acts as an antioxidant and delays programmed cell death in barley aleurone layers.
    Plant physiology, 2002, Volume: 129, Issue:4

    Topics: Abscisic Acid; alpha-Amylases; Antioxidants; Apoptosis; Benzoates; Butylated Hydroxytoluene; Catalase; Cell Survival; Fluorescent Dyes; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Plant; Gibberellins; Hordeum; Imidazoles; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Oxygen Consumption; Penicillamine; Protoplasts; Reactive Oxygen Species; RNA, Messenger; Seeds; Superoxide Dismutase

2002
Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice.
    European journal of pharmacology, 2003, Mar-19, Volume: 464, Issue:2-3

    Topics: Alkaloids; Amylases; Animals; Azepines; Benzoates; Benzylamines; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Carbazoles; Chelating Agents; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gallic Acid; Genotype; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Indoles; Male; Mice; Mice, Knockout; Molsidomine; Muscarinic Agonists; Myosin-Light-Chain Kinase; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Parotid Gland; Penicillamine; Phosphodiesterase Inhibitors; Pilocarpine; Protein Kinase Inhibitors; Pyrroles; Pyrrolidinones; Quinoxalines; Quinuclidines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Type C Phospholipases

2003
Metamodulation of a spinal locomotor network by nitric oxide.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Oct-27, Volume: 24, Issue:43

    Topics: Adrenergic alpha-Antagonists; Animals; Benzoates; Embryo, Nonmammalian; gamma-Aminobutyric Acid; Glycine; Imidazoles; Larva; Membrane Potentials; Neural Inhibition; Nitric Oxide; Nitric Oxide Donors; Norepinephrine; Penicillamine; Phentolamine; Spinal Cord; Swimming; Synapses; Time Factors; Xenopus laevis

2004
Nitric oxide donors can enhance the intestinal transport and absorption of insulin and [Asu(1,7)]-eel calcitonin in rats.
    Journal of controlled release : official journal of the Controlled Release Society, 2005, Sep-02, Volume: 106, Issue:3

    Topics: Animals; Benzoates; Calcitonin; Drug Stability; Imidazoles; Insulin; Intestinal Absorption; Male; Nitric Oxide Donors; Penicillamine; Rats; Rats, Wistar

2005
Ischemia/reperfusion-induced death of cardiac myocytes: possible involvement of nitric oxide in the coordination of ATP supply and demand during ischemia.
    Journal of molecular and cellular cardiology, 2006, Volume: 40, Issue:1

    Topics: Adenosine Triphosphate; Animals; Benzoates; Cell Death; Cells, Cultured; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Imidazoles; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; omega-N-Methylarginine; Ornithine; Penicillamine; Rats; Rats, Wistar

2006
Mitochondrial involvement in nitric oxide-induced cellular death in cortical neurons in culture.
    Journal of neuroscience research, 2006, Feb-15, Volume: 83, Issue:3

    Topics: Adenosine Triphosphate; Anaphase-Promoting Complex-Cyclosome; Animals; Benzoates; Blotting, Western; Caspase 3; Caspase 9; Caspases; Cell Death; Cell Survival; Cells, Cultured; Cerebral Cortex; Cytochromes; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Imidazoles; Intracellular Space; L-Lactate Dehydrogenase; Membrane Potentials; Mitochondria; Neuroglia; Neurons; Nitric Oxide; Nitric Oxide Donors; Penicillamine; Rats; Reactive Oxygen Species; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligase Complexes

2006
Exogenous nitric oxide inhibits IRS-1 expression in rat hepatocytes and skeletal myocytes.
    Journal of biomedical science, 2006, Volume: 13, Issue:4

    Topics: Animals; Benzoates; Gene Expression Regulation; Glutathione; Hepatocytes; Imidazoles; Immunoblotting; Insulin Receptor Substrate Proteins; Muscle Fibers, Skeletal; Nitric Oxide; Nitro Compounds; Penicillamine; Phosphoproteins; Rats; Signal Transduction; Time Factors

2006
Nitric oxide production by the vacuolar-type (H+)-ATPase inhibitors bafilomycin A1 and concanamycin A and its possible role in apoptosis in RAW 264.7 cells.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:2

    Topics: Animals; Anthracenes; Apoptosis; Benzoates; Cell Line; Cell Proliferation; Dibucaine; Enzyme Inhibitors; Imidazoles; Macrolides; Mice; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Nitriles; Oligomycins; omega-N-Methylarginine; Penicillamine; Phosphorylation; RNA, Messenger; Sulfones; Thapsigargin; Transcription Factor AP-1; Vacuolar Proton-Translocating ATPases

2006
Effect of exogenous nitric oxide on murine splenic immune response induced by Aggregatibacter actinomycetemcomitans lipopolysaccharide.
    Anaerobe, 2009, Volume: 15, Issue:3

    Topics: Animals; Benzoates; Cells, Cultured; Female; Imidazoles; Immunoglobulin G; Immunologic Factors; Interferon-gamma; Interleukin-4; Leukocytes, Mononuclear; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase Type II; Pasteurellaceae; Penicillamine; Spleen

2009