penbutolol has been researched along with metoprolol in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (38.89) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carrupt, PA; Gaillard, P; Schambel, P; Testa, B | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Caron, G; Ermondi, G | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bard, B; Carrupt, PA; Martel, S | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Jones, LH; Nadanaciva, S; Rana, P; Will, Y | 1 |
| Hansson, BG; Hökfelt, B | 1 |
| Boucher, M; Chapuy, E; Duchêne-Marullaz, P | 1 |
| Johansson, SR; McCall, M; Vedin, JA; Wilhelmsson, C | 1 |
| Kirch, W; Mutschler, E; Spahn, H | 2 |
| Dymling, JF; Hansson, BG; Hökfelt, B; Manhem, P | 1 |
| Kuhn, S; Mucklow, JC | 1 |
| Chadha, DR; Houtzagers, JJ | 1 |
| Hjorth, S; Sharp, T | 1 |
| Arnt, J; Moltzen, EK; Sánchez, C | 1 |
1 review(s) available for penbutolol and metoprolol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 trial(s) available for penbutolol and metoprolol
| Article | Year |
|---|---|
Duration of action of beta blockers.
Topics: Adrenergic beta-Antagonists; Adult; Alprenolol; Atenolol; Blood Pressure; Coronary Disease; Heart Rate; Humans; Metoprolol; Penbutolol; Physical Exertion; Pindolol; Propranolol; Regression Analysis; Rest; Sotalol; Time Factors; Timolol | 1980 |
The comparative beta-adrenoceptor blocking effects of penbutolol, atenolol and sustained-release metoprolol in healthy volunteers.
Topics: Adolescent; Adult; Atenolol; Blood Pressure; Delayed-Action Preparations; Heart Rate; Humans; Male; Maximal Expiratory Flow Rate; Metoprolol; Middle Aged; Penbutolol; Propanolamines | 1984 |
Once-daily penbutolol or atenolol can replace combination therapy in essential hypertension.
Topics: Atenolol; Blood Pressure; Chlorthalidone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Metoprolol; Penbutolol; Propanolamines; Propranolol; Pulse | 1982 |
14 other study(ies) available for penbutolol and metoprolol
| Article | Year |
|---|---|
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes | 1996 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Lipophilicity of basic drugs measured by hydrophilic interaction chromatography.
Topics: Chemistry, Pharmaceutical; Chromatography; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Pharmaceutical Preparations; Solubility; Technology, Pharmaceutical | 2009 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone | 2016 |
Negative consequences of blood pressure reduction. The effect of sympathetic inhibition on plasma levels of catecholamines, growth hormone, glucagon and cortisol.
Topics: Adrenergic beta-Antagonists; Blood Glucose; Catecholamines; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hypertension; Metoprolol; Penbutolol; Physical Exertion; Posture | 1979 |
Membrane stabilizing activity and beta-adrenoceptor antagonist-induced bradycardia in conscious dogs.
Topics: Adrenergic beta-Antagonists; Animals; Atrial Function; Bradycardia; Consciousness; Dogs; Dose-Response Relationship, Drug; Female; Heart Atria; Heart Block; Heart Rate; Heart Ventricles; Male; Membranes; Metoprolol; Penbutolol; Pindolol; Propranolol; Refractory Period, Electrophysiological; Stereoisomerism; Ventricular Function | 1992 |
The interaction between H2-receptor antagonists and beta-adrenoceptor blockers.
Topics: Adrenergic beta-Antagonists; Atenolol; Cimetidine; Drug Interactions; Histamine H2 Antagonists; Humans; Kinetics; Metoprolol; Penbutolol; Pindolol; Propranolol; Ranitidine | 1984 |
Effects of penbutolol and metoprolol on blood pressure, plasma catecholamines and renin activity in hypertensive patients.
Topics: Aldosterone; Blood Pressure; Catecholamines; Female; Humans; Hypertension; Male; Metoprolol; Penbutolol; Pilot Projects; Propanolamines; Renin | 1983 |
The interaction of cimetidine with metoprolol, atenolol, propranolol, pindolol and penbutolol.
Topics: Atenolol; Biological Availability; Cimetidine; Drug Interactions; Guanidines; Humans; Metoprolol; Penbutolol; Pindolol; Propanolamines; Propranolol | 1983 |
In vivo microdialysis evidence for central serotonin1A and serotonin1B autoreceptor blocking properties of the beta adrenoceptor antagonist (-)penbutolol.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Animals; Citalopram; Dialysis; Hippocampus; Male; Metoprolol; Penbutolol; Perfusion; Pindolol; Propanolamines; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stereoisomerism | 1993 |
The antiaggressive potency of (-)-penbutolol involves both 5-HT1A and 5-HT1B receptors and beta-adrenoceptors.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic beta-Antagonists; Aggression; Animals; Male; Methoxydimethyltryptamines; Metoprolol; Mice; Penbutolol; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Social Isolation | 1996 |