pectins has been researched along with repaglinide* in 1 studies
1 other study(ies) available for pectins and repaglinide
| Article | Year |
|---|---|
Dual crosslinked pectin-alginate network as sustained release hydrophilic matrix for repaglinide.
Repaglinide, an oral antidiabetic agent, has a rapid onset of action and short half-life of approximately 1h. Developing a controlled and prolonged release delivery system is required to maintain its therapeutic plasma concentration and to eliminate its adverse effects particularly hypoglycemia. The present study aimed to develop controlled release repaglinide loaded beads using sodium alginate and pectin with dual cross-linking for effective control of drug release. The prepared beads were characterized for size, percentage drug entrapment efficiency, in vitro drug release and the morphological examination using scanning electron microscope. For the comparative study, the release profile of a marketed conventional tablet of repaglinide (Prandin Topics: Adhesiveness; Alginates; Carbamates; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Epichlorohydrin; Glucuronic Acid; Hexuronic Acids; Hydrophobic and Hydrophilic Interactions; Kinetics; Mucous Membrane; Particle Size; Pectins; Piperidines; Temperature | 2017 |