pd 98059 has been researched along with transforming growth factor alpha in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 20 (80.00) | 29.6817 |
| 2010's | 4 (16.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arata, J; Dannenberg, AJ; Eling, TE; Inoue, H; Jetten, AM; Kamitani, H; Matsuura, H; Sakaue, M; Subbaramaiah, K; Tanabe, T | 1 |
| Atabai, K; Geiser, T; Jarreau, PH; Matthay, MA | 1 |
| Pouysségur, J; Viñals, F | 1 |
| Crawford, JM; Sautin, YY; Svetlov, SI | 1 |
| Brattain, MG; Dawson, DM; Gupta, A; St Clair, P; Venkateswarlu, S; Willson, JK | 1 |
| Firestone, GL; Guan, Y; Rubenstein, NM; Woo, PL | 1 |
| Akahoshi, T; Inoue, M; Kawai, S; Kitasato, H; Koshino, T; Murakami, Y; Noda, M; Okamoto, R | 1 |
| Aubert, JP; Copin, MC; Perrais, M; Pigny, P; Van Seuningen, I | 1 |
| Bilter, GK; Der, CJ; Pruitt, K; Pruitt, WM; Westwick, JK | 1 |
| Conaway, M; Li, Y; Masamura, S; Santen, RJ; Wang, JP; Yue, W | 1 |
| Barrow, D; Gee, JM; Harper, ME; Hutcheson, IR; Jones, HE; Knowlden, JM; Madden, T; Nicholson, RI; Wakeling, AE | 1 |
| Brattain, MG; Humphrey, LE; Sawhney, RS; Sharma, B | 1 |
| Li, J; Majumdar, AP; Xiao, ZQ | 1 |
| Davidson, MK; Draper, BK; Komurasaki, T; Nanney, LB | 1 |
| Kruger, JS; Reddy, KB | 1 |
| Beug, H; Damiola, F; Dazy, S; Gandrillon, O; Parisey, N | 1 |
| Cohick, WS; Desury, G; Fleming, J; Hogan, KA; Sivaprasad, U; Verma, PS | 1 |
| Bowling, GH; Khan, SA; Millena, AC; Reddy, SC | 1 |
| Kimura, M; Ogihara, M | 1 |
| Matsumura, F; Park, S | 1 |
| Lin, L; Zheng, Y; Zheng, Z | 1 |
| Levchenko, V; Pavlov, TS; Staruschenko, A; Vandewalle, A; Wilson, PD; Zheleznova, NN | 1 |
| Bollinger, N; Joslin, EJ; Lauffenburger, DA; Opresko, LK; Shankaran, H; Wiley, HS | 1 |
| Chang, LH; Lai, CY; Pan, SL; Teng, CM; Tsai, AC | 1 |
| Kimura, M; Moteki, H; Ogihara, M | 1 |
25 other study(ies) available for pd 98059 and transforming growth factor alpha
| Article | Year |
|---|---|
Regulation of cyclooxygenase-2 by interferon gamma and transforming growth factor alpha in normal human epidermal keratinocytes and squamous carcinoma cells. Role of mitogen-activated protein kinases.
Topics: Amphiregulin; Carcinoma, Squamous Cell; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; EGF Family of Proteins; Eicosanoids; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Gene Expression Regulation, Enzymologic; Glycoproteins; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Interferon-gamma; Isoenzymes; Keratinocytes; Membrane Proteins; Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Regulatory Sequences, Nucleic Acid; RNA, Messenger; Signal Transduction; Transforming Growth Factor alpha; Tumor Cells, Cultured | 1999 |
Interleukin-1beta augments in vitro alveolar epithelial repair.
Topics: Animals; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Flavonoids; In Vitro Techniques; Interleukin-1; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome; Respiratory Mucosa; Specific Pathogen-Free Organisms; Transforming Growth Factor alpha; Wound Healing | 2000 |
Transforming growth factor beta1 (TGF-beta1) promotes endothelial cell survival during in vitro angiogenesis via an autocrine mechanism implicating TGF-alpha signaling.
Topics: Androstadienes; Animals; Blotting, Northern; Blotting, Western; Cell Death; Cell Line; Cell Survival; Cells, Cultured; Chromones; Collagen Type I; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neovascularization, Physiologic; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Binding; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Transforming Growth Factor alpha; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrphostins; Wortmannin | 2001 |
Enhancement of survival by LPA via Erk1/Erk2 and PI 3-kinase/Akt pathways in a murine hepatocyte cell line.
Topics: Androstadienes; Animals; Apoptosis; Bacterial Toxins; Butadienes; Cell Line; Chromones; DNA; Enterotoxins; Enzyme Inhibitors; Flavonoids; Hepatocytes; Humans; Lysophospholipids; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha; Wortmannin | 2001 |
Autocrine heregulin generates growth factor independence and blocks apoptosis in colon cancer cells.
Topics: Adenocarcinoma; Apoptosis; Autocrine Communication; Cell Cycle; Chromones; Colonic Neoplasms; Culture Media; Culture Media, Serum-Free; Dimerization; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Neoplastic; Genes, erbB-2; Growth Substances; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neoplasm Proteins; Neuregulin-1; Neutralization Tests; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, ErbB-3; Signal Transduction; Sirolimus; Transfection; Transforming Growth Factor alpha; Tumor Cells, Cultured | 2002 |
Transforming growth factor-alpha abrogates the glucocorticoid stimulation of tight junction formation and reverses the steroid-induced down-regulation of fascin in rat mammary epithelial tumor cells by a Ras-dependent pathway.
Topics: Actins; Animals; Anti-Inflammatory Agents; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Communication; Dexamethasone; Down-Regulation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Mammary Neoplasms, Experimental; Membrane Potentials; Membrane Proteins; Microfilament Proteins; Phosphoproteins; ras Proteins; Rats; Receptors, Glucocorticoid; Tight Junctions; Transforming Growth Factor alpha; Tumor Cells, Cultured; Zonula Occludens-1 Protein | 2002 |
Activated Ras modifies the proliferative response of rheumatoid synovial cells to TNF-alpha and TGF-alpha.
Topics: Apoptosis; Arthritis, Rheumatoid; Blotting, Northern; Cell Division; Cell Survival; Cells, Cultured; Enzyme Inhibitors; Fibroblasts; Flavonoids; Gene Expression Regulation; Humans; Mitogen-Activated Protein Kinases; Oncogene Protein p21(ras); Signal Transduction; Stimulation, Chemical; Synovial Membrane; Transforming Growth Factor alpha; Tumor Necrosis Factor-alpha | 2001 |
Induction of MUC2 and MUC5AC mucins by factors of the epidermal growth factor (EGF) family is mediated by EGF receptor/Ras/Raf/extracellular signal-regulated kinase cascade and Sp1.
Topics: Base Sequence; Carcinoma, Squamous Cell; DNA Primers; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Mucin 5AC; Mucin-2; Mucins; Polymerase Chain Reaction; ras Proteins; Sp1 Transcription Factor; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
Raf-independent deregulation of p38 and JNK mitogen-activated protein kinases are critical for Ras transformation.
Topics: Animals; Cell Cycle; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cloning, Molecular; Culture Media, Conditioned; Cyclin D1; Cyclins; Enzyme Inhibitors; Flavonoids; Genes, ras; Imidazoles; Intestinal Mucosa; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Pyridines; Rats; Recombinant Proteins; Transforming Growth Factor alpha | 2002 |
Activation of the MAPK pathway enhances sensitivity of MCF-7 breast cancer cells to the mitogenic effect of estradiol.
Topics: Breast Neoplasms; Cell Cycle; Cell Cycle Proteins; Cell Division; DNA-Binding Proteins; Dose-Response Relationship, Drug; E2F Transcription Factors; E2F1 Transcription Factor; Enzyme Activation; Enzyme Inhibitors; Estradiol; Flavonoids; Gene Expression; Humans; Mitogen-Activated Protein Kinases; Proteins; Receptors, Estrogen; Receptors, Progesterone; Response Elements; Transcription Factors; Transcription, Genetic; Transforming Growth Factor alpha; Trefoil Factor-1; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2002 |
Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Breast Neoplasms; Cell Division; Dimerization; Drug Resistance, Neoplasm; ErbB Receptors; Flavonoids; Gefitinib; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Quinazolines; Receptor, ErbB-2; RNA, Messenger; Tamoxifen; Transforming Growth Factor alpha; Trastuzumab; Tumor Cells, Cultured | 2003 |
Integrin alpha2 and extracellular signal-regulated kinase are functionally linked in highly malignant autocrine transforming growth factor-alpha-driven colon cancer cells.
Topics: Butadienes; Chromones; Colonic Neoplasms; Enzyme Inhibitors; Flavonoids; Humans; Integrin alpha2; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Transforming Growth Factor alpha; Tumor Cells, Cultured | 2003 |
Regulation of TGF-alpha-induced activation of AP-1 in the aging gastric mucosa.
Topics: Aging; Animals; DNA; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Gastric Mucosa; Male; Mitogen-Activated Protein Kinase Kinases; Pyrimidines; Quinazolines; Rats; Rats, Inbred F344; Signal Transduction; src-Family Kinases; Transcription Factor AP-1; Transforming Growth Factor alpha | 2003 |
Epiregulin is more potent than EGF or TGFalpha in promoting in vitro wound closure due to enhanced ERK/MAPK activation.
Topics: Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epiregulin; Flavonoids; Humans; Immunoblotting; In Vitro Techniques; Keratinocytes; Mitogen-Activated Protein Kinases; Mitomycin; Nucleic Acid Synthesis Inhibitors; Signal Transduction; Transforming Growth Factor alpha; Wound Healing | 2003 |
Distinct mechanisms mediate the initial and sustained phases of cell migration in epidermal growth factor receptor-overexpressing cells.
Topics: Breast Neoplasms; Cell Division; Cell Line, Tumor; Cell Movement; ErbB Receptors; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Myosin-Light-Chain Kinase; Phorbol 12,13-Dibutyrate; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Protein Serine-Threonine Kinases; rho-Associated Kinases; Transforming Growth Factor alpha; Tyrosine | 2003 |
The MEK-1/ERKs signalling pathway is differentially involved in the self-renewal of early and late avian erythroid progenitor cells.
Topics: Animals; Blotting, Western; Butadienes; Cell Differentiation; Cell Division; Cell Lineage; Chickens; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Flavonoids; Flow Cytometry; Humans; In Situ Nick-End Labeling; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Nitriles; Oligopeptides; Protein Serine-Threonine Kinases; Recombinant Proteins; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Stem Cells; Time Factors; Transforming Growth Factor alpha | 2003 |
Stimulation of insulin-like growth factor (IGF) binding protein-3 synthesis by IGF-I and transforming growth factor-alpha is mediated by both phosphatidylinositol-3 kinase and mitogen-activated protein kinase pathways in mammary epithelial cells.
Topics: Animals; Cattle; Cell Line; Chromones; DNA; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Flavonoids; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Mammary Glands, Animal; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; RNA, Messenger; Transforming Growth Factor alpha | 2004 |
Autocrine regulation of steroidogenic function of Leydig cells by transforming growth factor-alpha.
Topics: Androgens; Animals; Autocrine Communication; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Flavonoids; Gene Expression Regulation; Isoquinolines; Leydig Cells; Luteinizing Hormone; Male; Mitogen-Activated Protein Kinases; Phosphoproteins; Quinazolines; Rats; RNA, Messenger; Steroids; Sulfonamides; Transforming Growth Factor alpha; Tyrphostins | 2004 |
Effects of branched-chain amino acids on DNA synthesis and proliferation in primary cultures of adult rat hepatocytes.
Topics: Amino Acids, Branched-Chain; Animals; Antibodies, Monoclonal; Cell Proliferation; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Hepatocytes; Isoleucine; Leucine; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Models, Biological; Phosphoinositide-3 Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Receptor, IGF Type 1; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Transforming Growth Factor alpha; Type C Phospholipases; Valine | 2005 |
Characterization of anti-apoptotic action of TCDD as a defensive cellular stress response reaction against the cell damaging action of ultra-violet irradiation in an immortalized normal human mammary epithelial cell line, MCF10A.
Topics: Adaptation, Physiological; alpha 1-Antitrypsin; Apoptosis; bcl-2-Associated X Protein; Benzoflavones; Butadienes; Cell Line; DNA Fragmentation; Epidermal Growth Factor; Epithelial Cells; Female; Ferric Compounds; Flavonoids; Glutathione; Humans; Hydrogen Peroxide; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Nitriles; Nitro Compounds; Phenanthrolines; Polychlorinated Dibenzodioxins; Pyrimidines; Pyrroles; Quaternary Ammonium Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transforming Growth Factor alpha; Ultraviolet Rays | 2006 |
TGF-alpha induces upregulation and nuclear translocation of Hes1 in glioma cell.
Topics: Active Transport, Cell Nucleus; Amyloid Precursor Protein Secretases; Basic Helix-Loop-Helix Transcription Factors; Blotting, Western; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Dipeptides; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation, Neoplastic; Glioma; Homeodomain Proteins; Humans; Immunoglobulin J Recombination Signal Sequence-Binding Protein; Phosphorylation; Protease Inhibitors; Protein Kinase Inhibitors; Protein Transport; Receptors, Notch; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription Factor HES-1; Transforming Growth Factor alpha; Up-Regulation | 2008 |
EGF and its related growth factors mediate sodium transport in mpkCCDc14 cells via ErbB2 (neu/HER-2) receptor.
Topics: Amiloride; Amphiregulin; Animals; Benzothiazoles; Blotting, Western; Butadienes; Cell Line; Chromones; Dose-Response Relationship, Drug; EGF Family of Proteins; Epidermal Growth Factor; Epithelial Sodium Channels; Flavonoids; Glycoproteins; Heparin-binding EGF-like Growth Factor; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Ion Transport; Kidney Tubules, Collecting; Kinetics; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, ErbB-2; Sodium; Sodium Channel Blockers; Transforming Growth Factor alpha; Tyrphostins | 2010 |
Structure of the EGF receptor transactivation circuit integrates multiple signals with cell context.
Topics: Cell Line; Dose-Response Relationship, Drug; Epithelial Cells; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gefitinib; Gene Regulatory Networks; Hepatocyte Growth Factor; Humans; Imidazoles; Ligands; Lysophospholipids; Mammary Glands, Human; Phosphorylation; Pyridines; Quinazolines; Signal Transduction; Transcriptional Activation; Transforming Growth Factor alpha | 2010 |
Activated PAR-2 regulates pancreatic cancer progression through ILK/HIF-α-induced TGF-α expression and MEK/VEGF-A-mediated angiogenesis.
Topics: Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Down-Regulation; Flavonoids; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indazoles; Mitogen-Activated Protein Kinase Kinases; Neovascularization, Pathologic; Pancreatic Neoplasms; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Receptor, PAR-2; RNA, Small Interfering; Signal Transduction; Transforming Growth Factor alpha; Up-Regulation; Vascular Endothelial Growth Factor A | 2013 |
Involvement of endogenous transforming growth factor-α in signal transduction pathway for interleukin-1β-induced hepatocyte proliferation.
Topics: Animals; Cell Cycle; Cell Proliferation; Cells, Cultured; Chromones; DNA; Dose-Response Relationship, Drug; Flavonoids; Hepatocytes; Interleukin 1 Receptor Antagonist Protein; Interleukin-1alpha; Interleukin-1beta; Male; MAP Kinase Signaling System; Morpholines; Quinazolines; Rats; Rats, Wistar; Signal Transduction; Sirolimus; Transforming Growth Factor alpha; Tyrphostins | 2014 |