pd 98059 and thromboplastin

pd 98059 has been researched along with thromboplastin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (25.00)18.2507
2000's10 (50.00)29.6817
2010's5 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bitar, R; Dackiw, AP; Davreux, CJ; Lu, Z; McGilvray, ID; Rotstein, OD1
Boneu, B; Constans, J; Sié, P; Xuereb, JM2
Bergenhem, NC; Ezban, M; Foster, DC; Jacobsen, N; Kelly, JD; Petersen, LC; Poulsen, LK; Sørensen, BB; Thastrup, O1
Linder, S; Ljungdahl, S; Shoshan, MC; Swedenborg, J; Zhou, JN1
Dackiw, AP; Kapus, A; Levy, G; Lu, Z; Marshall, JC; McGilvray, ID; Rotstein, OD; Wei, AC1
Binder, BR; Clauss, M; Hofer, E; Lucerna, M; Mechtcheriakova, D; Schabbauer, G1
Guha, M; Hollis, A; Mackman, N; McGovern, P; O'Connell, MA; Pawlinski, R; Stern, D; Yan, SF1
Peppelenbosch, MP; Petersen, LC; Richel, DJ; Slofstra, SH; Stam, JC; Sørensen, BB; van Bergen en Henegouwen, PM; Van den Brande, JH; Versteeg, HH1
Dackiw, AP; Marshall, JC; McGilvray, ID; Rotstein, OD; Tsai, V1
Fujisawa, K; Hata, Y; Hisatomi, T; Honda, M; Ishibashi, T; Kubota, T; Murata, T; Nakagawa, K; Sakamoto, T; Sassa, Y; Sueishi, K; Yamanaka, I1
Aoki, S; Gabazza, EC; Suzuki, K; Takeya, H; Ueno, H1
Bucciarelli, LG; Harja, E; Lu, Y; Schmidt, AM; Stern, DM; Yan, SF; Zou, YS1
Barbarroja, N; Buendía, P; Dorado, G; López-Pedrera, C; Torres, A; Velasco, F1
Liu, YC; Pan, YS; Rong, L; Tang, JQ; Wan, YL; Wang, X; Wu, T; Zhu, J1
Akhmedov, A; Angstenberger, J; Camici, GG; Gebhard, C; Lüscher, TF; Mocharla, P; Sahbai, S; Tanner, FC1
Guyton, RA; Jiang, R; Levy, JH; Tanaka, KA; Vinten-Johansen, J; Wang, NP; Zhao, ZQ1
Abe, R; Madri, JA; Nixon, A; Rochier, A; Sumpio, BE; Yamashita, N1
Biswas, I; Garg, I; Khan, GA; Singh, B1
Aoki, M; Hirose, E; Ishimaru, Y; Kawata, J; Matsmoto, T; Narahara, S; Ono, T; Sagara, K; Yamaguchi, Y1

Other Studies

20 other study(ies) available for pd 98059 and thromboplastin

ArticleYear
VLA-4 integrin cross-linking on human monocytic THP-1 cells induces tissue factor expression by a mechanism involving mitogen-activated protein kinase.
    The Journal of biological chemistry, 1997, Apr-11, Volume: 272, Issue:15

    Topics: Calcium-Calmodulin-Dependent Protein Kinases; DNA-Binding Proteins; Enzyme Inhibitors; Fibronectins; Flavonoids; Genistein; Humans; Integrin alpha4beta1; Integrin beta1; Integrins; Isoflavones; NF-kappa B; Nuclear Proteins; Phosphorylation; Receptors, Lymphocyte Homing; Receptors, Very Late Antigen; Thromboplastin; Trans-Activators; Tyrosine; Viral Proteins; Zinc Fingers

1997
Up-regulation of tissue factor expression by platelet-derived growth factor in human vascular smooth muscle cells in culture--role of mitogen-activated protein kinase and effects of intracellular cyclic AMP.
    Thrombosis and haemostasis, 1997, Volume: 78, Issue:6

    Topics: Adult; Antigens; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic AMP; Enzyme Inhibitors; Flavonoids; Humans; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Signal Transduction; Thromboplastin; Up-Regulation

1997
Signal transduction via the mitogen-activated protein kinase pathway induced by binding of coagulation factor VIIa to tissue factor.
    The Journal of biological chemistry, 1998, Mar-13, Volume: 273, Issue:11

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cricetinae; Dogs; Factor VII; Factor VIIa; Factor X; Factor Xa; Flavonoids; Gene Expression Regulation; Genes, Reporter; Kidney; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Recombinant Proteins; Signal Transduction; Thromboplastin

1998
Activation of tissue-factor gene expression in breast carcinoma cells by stimulation of the RAF-ERK signaling pathway.
    Molecular carcinogenesis, 1998, Volume: 21, Issue:4

    Topics: Base Sequence; Benzoquinones; Breast Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Dactinomycin; DNA, Complementary; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Genistein; Humans; Hydroquinones; Lactams, Macrocyclic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neovascularization, Pathologic; NF-kappa B; Okadaic Acid; Phenols; Proto-Oncogene Proteins c-raf; Quinones; Rifabutin; Signal Transduction; Tetradecanoylphorbol Acetate; Thromboplastin; Transcription Factor AP-1; Transcription, Genetic; Tretinoin; Tumor Cells, Cultured

1998
Murine hepatitis virus strain 3 induces the macrophage prothrombinase fgl-2 through p38 mitogen-activated protein kinase activation.
    The Journal of biological chemistry, 1998, Nov-27, Volume: 273, Issue:48

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Induction; Enzyme Inhibitors; Female; Fibrinogen; Flavonoids; Gene Expression Regulation; Imidazoles; Kinetics; Macrophages, Peritoneal; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Murine hepatitis virus; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction; Thromboplastin

1998
Inhibition of tissue factor synthesis by disruption of ERK kinases and PKC signaling pathways in human vascular SMCs.
    Thrombosis and haemostasis, 2000, Volume: 84, Issue:1

    Topics: Adult; Animals; Cattle; Cells, Cultured; Culture Media; Culture Media, Serum-Free; Enzyme Activation; Enzyme Inhibitors; Fetal Blood; Fibroblast Growth Factor 2; Flavonoids; Gene Expression Regulation; Genes, Immediate-Early; Humans; Lipopolysaccharides; Mammary Arteries; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Naphthalenes; Platelet-Derived Growth Factor; Polyenes; Polyunsaturated Alkamides; Protein Kinase C; Thrombin; Thromboplastin

2000
Specificity, diversity, and convergence in VEGF and TNF-alpha signaling events leading to tissue factor up-regulation via EGR-1 in endothelial cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2001, Volume: 15, Issue:1

    Topics: Cells, Cultured; DNA-Binding Proteins; Early Growth Response Protein 1; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Epidermal Growth Factor; Flavonoids; Genes, Dominant; Humans; I-kappa B Kinase; Immediate-Early Proteins; Lymphokines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutation; Protein Kinase C; Protein Serine-Threonine Kinases; Receptor Cross-Talk; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Substrate Specificity; Tetradecanoylphorbol Acetate; Thromboplastin; Transcription Factors; Tumor Necrosis Factor-alpha; Umbilical Veins; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2001
Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor alpha expression by inducing Elk-1 phosphorylation and Egr-1 expression.
    Blood, 2001, Sep-01, Volume: 98, Issue:5

    Topics: DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Activation; Enzyme Inhibitors; ets-Domain Protein Elk-1; Flavonoids; Gene Expression Regulation; Humans; Immediate-Early Proteins; Lipopolysaccharides; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Thromboplastin; Transcription Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

2001
VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation.
    The Journal of biological chemistry, 2002, Jul-26, Volume: 277, Issue:30

    Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Cricetinae; Cytoplasm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eukaryotic Initiation Factor-4E; Factor VIIa; Flavonoids; Glycogen Synthase Kinase 3; Humans; Peptide Initiation Factors; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; Sirolimus; Thrombin; Thromboplastin; Time Factors; Transfection; Up-Regulation

2002
Monocyte adhesion and transmigration induce tissue factor expression: role of the mitogen-activated protein kinases.
    Shock (Augusta, Ga.), 2002, Volume: 18, Issue:1

    Topics: Antibodies; CD18 Antigens; Cell Adhesion; Cell Movement; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Fibronectins; Flavonoids; Humans; Imidazoles; Inflammation; Integrin beta1; Mitogen-Activated Protein Kinases; Monocytes; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Pyridines; Thromboplastin; Tumor Necrosis Factor-alpha

2002
Functional role of Egr-1 mediating VEGF-induced tissue factor expression in the retinal capillary endothelium.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2002, Volume: 240, Issue:12

    Topics: Animals; Blotting, Western; Capillaries; Cattle; Cells, Cultured; DNA-Binding Proteins; Early Growth Response Protein 1; Electrophoretic Mobility Shift Assay; Endothelial Growth Factors; Endothelium, Vascular; Flavonoids; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Lymphokines; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Plicamycin; Rats; Rats, Inbred BN; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Thromboplastin; Transcription Factors; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
Synergistic effect of sphingosine 1-phosphate on thrombin-induced tissue factor expression in endothelial cells.
    Blood, 2003, Sep-01, Volume: 102, Issue:5

    Topics: Cells, Cultured; Drug Synergism; Endothelium, Vascular; Enzyme Inhibitors; Feedback, Physiological; Flavonoids; Gene Expression; Hemostatics; Humans; I-kappa B Proteins; Immediate-Early Proteins; Lysophospholipids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-KappaB Inhibitor alpha; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophospholipid; RNA, Messenger; Sphingosine; Thrombin; Thromboplastin; Umbilical Veins

2003
Early growth response-1 promotes atherogenesis: mice deficient in early growth response-1 and apolipoprotein E display decreased atherosclerosis and vascular inflammation.
    Circulation research, 2004, Feb-20, Volume: 94, Issue:3

    Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Blood Glucose; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chemokine CCL2; Cholesterol; Disease Progression; DNA-Binding Proteins; Early Growth Response Protein 1; Enzyme Inhibitors; Female; Flavonoids; Gene Expression; Immediate-Early Proteins; Intercellular Adhesion Molecule-1; Interleukin-1; Lipoproteins, LDL; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Plasminogen Activator Inhibitor 1; RNA, Messenger; Thromboplastin; Time Factors; Transcription Factors; Triglycerides; Vascular Cell Adhesion Molecule-1

2004
Promyelocytic leukemia retinoid signaling targets regulate apoptosis,tissue factor and thrombomodulin expression.
    Haematologica, 2004, Volume: 89, Issue:3

    Topics: Apoptosis; Benzoates; Cell Differentiation; Cell Line, Tumor; Flavonoids; Gene Expression; Humans; Leukemia, Promyelocytic, Acute; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Retinoids; Tetrahydronaphthalenes; Thrombomodulin; Thromboplastin

2004
[Regulation of promatrilysin expression by tissue factor/actived coagulation factor VII complex in LoVo colon cancer cell line].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2007, Oct-18, Volume: 39, Issue:5

    Topics: Anthracenes; Cell Line, Tumor; Colonic Neoplasms; Enzyme Inhibitors; Enzyme Precursors; Factor VII; Flavonoids; Humans; Imidazoles; MAP Kinase Signaling System; Matrix Metalloproteinase 7; Metalloendopeptidases; Pyridines; Thromboplastin

2007
PDGF-CC induces tissue factor expression: role of PDGF receptor alpha/beta.
    Basic research in cardiology, 2010, Volume: 105, Issue:3

    Topics: Becaplermin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Leukocytes, Mononuclear; Lymphokines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; RNA, Messenger; Thromboplastin

2010
Factor Xa induces tissue factor expression in endothelial cells by P44/42 MAPK and NF-κB-dependent pathways.
    The Journal of surgical research, 2011, Volume: 169, Issue:2

    Topics: Antithrombins; Cells, Cultured; Chromones; Endothelium, Vascular; Factor Xa; Flavonoids; Hirudins; Humans; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; NF-kappa B; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Sulfones; Thrombin; Thromboplastin; Up-Regulation

2011
Pulsatile to-fro flow induces greater and sustained expression of tissue factor RNA in HUVEC than unidirectional laminar flow.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:4

    Topics: Atherosclerosis; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; MAP Kinase Kinase Kinases; p38 Mitogen-Activated Protein Kinases; Pulsatile Flow; Pyridines; Stress, Mechanical; Thrombin; Thromboplastin

2011
A key role of toll-like receptor 3 in tissue factor activation through extracellular signal regulated kinase 1/2 pathway in a murine hypoxia model.
    Blood cells, molecules & diseases, 2012, Aug-15, Volume: 49, Issue:2

    Topics: Animals; Antibodies, Neutralizing; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fibrin; Flavonoids; Gene Expression Regulation; Hypoxia; Male; MAP Kinase Signaling System; Phosphorylation; Poly I-C; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Thromboplastin; Toll-Like Receptor 3

2012
Mechanism of tissue factor production by monocytes stimulated with neutrophil elastase.
    Blood cells, molecules & diseases, 2015, Volume: 54, Issue:2

    Topics: Calcium Channel Blockers; Carbazoles; Enzyme Inhibitors; Estrenes; Flavonoids; Gallic Acid; Gene Expression Regulation; Humans; Imidazoles; Indoles; Leukocyte Elastase; Maleimides; Monocytes; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Pyrrolidinones; RNA, Messenger; Signal Transduction; Thromboplastin; Type C Phospholipases

2015