pd 98059 has been researched along with threonine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 12 (60.00) | 29.6817 |
| 2010's | 3 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mothe, I; Van Obberghen, E | 1 |
| Avruch, J; Caudwell, FB; Cohen, P; Dalby, KN; Morrice, N | 1 |
| Bonavida, B; Mori, S; Murakami-Mori, K; Nakamura, S | 1 |
| Bandyopadhyay, G; Burke, TR; Farese, RV; Quon, MJ; Sajan, MP; Standaert, ML | 1 |
| Campbell, DH; Daly, RJ; Sutherland, RL | 1 |
| Chiariello, M; Gomez, E; Gutkind, JS | 1 |
| Kar, S; Quirion, R; Zheng, WH | 1 |
| Castranova, V; Ding, M; Huang, C; Leonard, SS; Li, J; Shi, X; Vallyathan, V; Wang, L | 1 |
| Calvo, V; Gomez-Cambronero, J; Lehman, JA | 1 |
| Katada, T; Kontani, K; Kurosu, H; Momose, H; Nishina, H; Tsujimoto, N; Tsujita, K | 1 |
| Ito, F; Takeuchi, K | 1 |
| Ishikawa, K; Tokumoto, T; Watanabe, K | 1 |
| Cheng, AL; Chuang, SE; Song, YC; Yeh, KH; Yeh, PY | 1 |
| Chang, NS; Heath, J; Hsu, LJ; Jambal, P; Pugazhenthi, S; Schultz, L; Su, M; Sze, CI | 1 |
| Chen, ST; Hsu, JR; Huang, HJ; Hung, SP; Lo, CP; Wang, JP | 1 |
| Inamura, N; Nawa, H; Takei, N | 1 |
| Brown, CM; Kodiha, M; Rassi, JG; Stochaj, U | 1 |
| Kapus, A; Malam, Z; Marshall, JC; Parodo, J; Szaszi, K; Waheed, F | 1 |
| Chen, SL; Gao, X; Li, B; Liu, Y; Mao, W; Wang, Z; Zhang, J | 1 |
| Beiras-Fernandez, A; Cetinkaya, A; Kubin, T; Richter, M; Schönburg, M; Walther, T | 1 |
20 other study(ies) available for pd 98059 and threonine
| Article | Year |
|---|---|
Phosphorylation of insulin receptor substrate-1 on multiple serine residues, 612, 632, 662, and 731, modulates insulin action.
Topics: Amino Acid Sequence; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cloning, Molecular; Enzyme Inhibitors; Ethers, Cyclic; Flavonoids; Humans; Insulin; Insulin Receptor Substrate Proteins; Molecular Sequence Data; Okadaic Acid; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Rats; Recombinant Proteins; Serine; Threonine; Transfection | 1996 |
Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Calcium-Calmodulin-Dependent Protein Kinases; COS Cells; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Mapping; Phosphorylation; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Tetradecanoylphorbol Acetate; Threonine | 1998 |
Implication of TNF receptor-I-mediated extracellular signal-regulated kinases 1 and 2 (ERK1/2) activation in growth of AIDS-associated Kaposi's sarcoma cells: a possible role of a novel death domain protein MADD in TNF-alpha-induced ERK1/2 activation in K
Topics: Acquired Immunodeficiency Syndrome; Antibodies, Monoclonal; Antigens, CD; Calcium-Calmodulin-Dependent Protein Kinases; Carrier Proteins; Cell Division; Dactinomycin; Death Domain Receptor Signaling Adaptor Proteins; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Growth Inhibitors; Growth Substances; Guanine Nucleotide Exchange Factors; Humans; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Sarcoma, Kaposi; Threonine; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine | 1999 |
Protein kinase C-zeta and phosphoinositide-dependent protein kinase-1 are required for insulin-induced activation of ERK in rat adipocytes.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adipocytes; Amino Acid Substitution; Androstadienes; Animals; Chromones; Enzyme Activation; Enzyme Inhibitors; Epididymis; Flavonoids; Genistein; Insulin; Kinetics; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Mutagenesis, Site-Directed; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Recombinant Proteins; Signal Transduction; src Homology Domains; Threonine; Wortmannin | 1999 |
Signaling pathways and structural domains required for phosphorylation of EMS1/cortactin.
Topics: Cell Adhesion; Cells, Cultured; Cortactin; Epidermal Growth Factor; Flavonoids; Humans; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Microfilament Proteins; Neoplasm Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Serine; src Homology Domains; Structure-Activity Relationship; Threonine | 1999 |
Regulation of cyclin-dependent kinase (Cdk) 2 Thr-160 phosphorylation and activity by mitogen-activated protein kinase in late G1 phase.
Topics: 3T3 Cells; Animals; Butadienes; CDC2-CDC28 Kinases; Cyclin A; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinases; DNA Replication; Flavonoids; G1 Phase; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Platelet-Derived Growth Factor; Protein Serine-Threonine Kinases; Threonine | 2000 |
Insulin-like growth factor-1-induced phosphorylation of the forkhead family transcription factor FKHRL1 is mediated by Akt kinase in PC12 cells.
Topics: 3T3 Cells; Androstadienes; Animals; Apoptosis; Blotting, Western; Cell Line; Cells, Cultured; Cerebellum; Cerebral Cortex; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Forkhead Box Protein O1; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Insulin-Like Growth Factor I; Mice; Mutagenesis; Myristic Acid; Nerve Tissue Proteins; Neurons; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Serine; Sirolimus; Threonine; Transcription Factors; Transfection; Vanadates; Wortmannin | 2000 |
UV Induces phosphorylation of protein kinase B (Akt) at Ser-473 and Thr-308 in mouse epidermal Cl 41 cells through hydrogen peroxide.
Topics: Animals; Epidermal Cells; Epidermis; Flavonoids; Free Radical Scavengers; Hydrogen Peroxide; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Serine; Threonine; Ultraviolet Rays | 2001 |
Mechanism of ribosomal p70S6 kinase activation by granulocyte macrophage colony-stimulating factor in neutrophils: cooperation of a MEK-related, THR421/SER424 kinase and a rapamycin-sensitive, m-TOR-related THR389 kinase.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Blotting, Western; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Granulocyte-Macrophage Colony-Stimulating Factor; Immunosuppressive Agents; Inhibitory Concentration 50; Kinetics; MAP Kinase Signaling System; Mice; Models, Biological; Neutrophils; Phosphorylation; Precipitin Tests; Protein Kinases; Ribosomal Protein S6 Kinases, 70-kDa; Ribosomes; Sirolimus; Threonine; Time Factors; TOR Serine-Threonine Kinases | 2003 |
Dual phosphorylation of phosphoinositide 3-kinase adaptor Grb2-associated binder 2 is responsible for superoxide formation synergistically stimulated by Fc gamma and formyl-methionyl-leucyl-phenylalanine receptors in differentiated THP-1 cells.
Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Cell Differentiation; Cell Line; Cross-Linking Reagents; Drug Synergism; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Humans; Mitogen-Activated Protein Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Formyl Peptide; Receptors, IgG; Serine; Superoxides; Threonine | 2003 |
Suppression of adriamycin-induced apoptosis by sustained activation of the phosphatidylinositol-3'-OH kinase-Akt pathway.
Topics: Antibiotics, Antineoplastic; Apoptosis; Biotin; Caspase 9; Caspases; Cell Line; Cell Line, Tumor; Cell Membrane; Chromones; DNA Fragmentation; Down-Regulation; Doxorubicin; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Flavonoids; Hepatocyte Growth Factor; Humans; Immunoblotting; Inositol; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-met; Recombinant Proteins; Serine; Signal Transduction; Threonine; Time Factors | 2004 |
1,10-Phenanthroline phosphorylates (activates) MAP kinase in Xenopus oocytes.
Topics: Animals; Blotting, Western; Butadienes; Cell-Free System; Chromones; Colforsin; Cycloheximide; Enzyme Inhibitors; Female; Flavonoids; Indoles; Kinetics; Maleimides; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oocytes; Pentetic Acid; Phenanthrolines; Phosphorylation; Progesterone; Threonine; Tyrosine; Xenopus laevis; Zinc Sulfate | 2003 |
Suppression of MEK/ERK signaling pathway enhances cisplatin-induced NF-kappaB activation by protein phosphatase 4-mediated NF-kappaB p65 Thr dephosphorylation.
Topics: Antineoplastic Agents; Cell Line; Cell Line, Tumor; Cell Nucleus; Cisplatin; Enzyme Activation; Enzyme Inhibitors; Escherichia coli; Flavonoids; Humans; Immunoblotting; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutagenesis, Site-Directed; NF-kappa B; Phosphoprotein Phosphatases; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Serine; Signal Transduction; Threonine; Transcription Factor RelA; Transfection | 2004 |
Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Anisomycin; Anthracenes; Brain; Cell Line; Cell Line, Tumor; COS Cells; Down-Regulation; Enzyme Inhibitors; Estradiol; Flavonoids; Genetic Vectors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Humans; Immunohistochemistry; In Vitro Techniques; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Neurons; Oxidoreductases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Retroviridae; RNA, Small Interfering; Serine; tau Proteins; Temperature; Threonine; Time Factors; Tumor Suppressor Proteins; Two-Hybrid System Techniques; Tyrosine; WW Domain-Containing Oxidoreductase | 2004 |
Genistein-induced neuronal differentiation is associated with activation of extracellular signal-regulated kinases and upregulation of p21 and N-cadherin.
Topics: Butadienes; Cadherins; Cell Differentiation; Cell Line; Cell Line, Tumor; Central Nervous System; Cyclin-Dependent Kinase 5; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Genistein; Humans; Immunoblotting; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Nitriles; Phosphotyrosine; Proto-Oncogene Proteins p21(ras); Threonine; Time Factors; Tretinoin; Up-Regulation | 2005 |
Enhancement of translation elongation in neurons by brain-derived neurotrophic factor: implications for mammalian target of rapamycin signaling.
Topics: Animals; Blotting, Western; Brain-Derived Neurotrophic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cerebral Cortex; Drug Interactions; Elongation Factor 2 Kinase; Flavonoids; Gene Expression Regulation; Immunohistochemistry; Microtubule-Associated Proteins; Neurons; Peptide Elongation Factor 1; Phosphorus Isotopes; Phosphorylation; Protein Biosynthesis; Protein Kinases; Rats; Ribosomes; RNA, Double-Stranded; Signal Transduction; Sirolimus; Threonine; Time Factors; TOR Serine-Threonine Kinases | 2005 |
Localization of AMP kinase is regulated by stress, cell density, and signaling through the MEK-->ERK1/2 pathway.
Topics: Active Transport, Cell Nucleus; Adenylate Kinase; Cell Count; Cell Nucleus; Cytoplasm; Exportin 1 Protein; Flavonoids; HeLa Cells; Hot Temperature; Humans; Karyopherins; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidative Stress; Peptides; Phosphorylation; Protein Kinase Inhibitors; Receptors, Cytoplasmic and Nuclear; Serum; Signal Transduction; Stress, Physiological; Threonine; Time Factors | 2007 |
Pre-B cell colony-enhancing factor (PBEF/Nampt/visfatin) primes neutrophils for augmented respiratory burst activity through partial assembly of the NADPH oxidase.
Topics: Blotting, Western; Cell Membrane; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; NADPH Oxidases; Neutrophils; Nicotinamide Phosphoribosyltransferase; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Subunits; Protein Transport; Pyridines; Reactive Oxygen Species; Respiratory Burst; Threonine | 2011 |
Resveratrol ameliorates low shear stress‑induced oxidative stress by suppressing ERK/eNOS‑Thr495 in endothelial cells.
Topics: Antioxidants; Atherosclerosis; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Human Umbilical Vein Endothelial Cells; Humans; L-Lactate Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Resveratrol; RNA, Messenger; Shear Strength; Stilbenes; Threonine | 2014 |
The MEK1 inhibitors UO126 and PD98059 block PDGF-AB induced phosphorylation of threonine 292 in porcine smooth muscle cells.
Topics: Animals; Butadienes; Cells, Cultured; Flavonoids; Male; MAP Kinase Kinase 1; Myocytes, Smooth Muscle; Nitriles; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Sus scrofa; Threonine | 2017 |