pd 98059 has been researched along with thapsigargin in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 15 (78.95) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Ohyashiki, T; Takadera, T | 1 |
| Chen, BC; Lin, LL; Lin, WW | 1 |
| Banfi, C; Battaini, F; Cattaneo, MG; Galli, C; Mussoni, L; Risé, P; Tremoli, E; Vicentini, L | 1 |
| Chao, PH; Henshaw, DR; Hung, CT; Mauck, RL; Mow, VC; Palmer, G; Raia, F; Ratcliffe, A; Valhmu, WB; Wang, CC | 1 |
| Bouillier, H; Dagher, G; Miserey, S; Perret, C; Renaud, JF; Safar, M; Samain, E | 1 |
| Hirasawa, N; Kobayashi, Y; Murakami, A; Ohuchi, K; Oikawa, S; Shiraishi, M | 1 |
| Barrett, KE; Calandrella, SO; Keely, SJ | 1 |
| Lin, WW; Wen, HC | 1 |
| Kozawa, O; Tokuda, H; Uematsu, T | 1 |
| Hirasawa, N; Murakami, A; Ohuchi, K | 1 |
| Dreja, K; Hellstrand, P; Hultgårdh-Nilsson, A; Lindqvist, A; Lövdahl, C; Moses, S | 1 |
| Abdel-Latif, AA; Ansari, HR; Husain, S | 1 |
| Chen, BC; Lin, WW | 1 |
| Bang, OS; Kang, SS; Park, JH | 1 |
| Hughes, TR; Irvine, SA; Mead, JR; Ramji, DP; Singh, NN | 1 |
| Baldwin, J; Bousquet, P; Chen, M; Dontenwill, M; Dupuy, L; Greney, H; Pascal, G; Piletz, JE; Rondé, P; Takeda, K; Urosevic, D | 1 |
| Donnellan, F; Geoghegan, P; Harvey, BJ; Keating, N; Keely, SJ; Murray, FE | 1 |
19 other study(ies) available for pd 98059 and thapsigargin
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Apoptotic cell death and CPP32-like activation induced by thapsigargin and their prevention by nerve growth factor in PC12 cells.
Topics: Animals; Apoptosis; Calcium; Calcium-Transporting ATPases; Caspase 1; Caspase 3; Caspases; Cycloheximide; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Flavonoids; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinase Kinases; Nerve Growth Factors; Neurons; Oligopeptides; PC12 Cells; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Rats; Thapsigargin | 1998 |
Protein kinase C epsilon-dependent pathway of extracellular signal-regulated protein kinase activation by P2Y1 and P2Y2 purinoceptors that activate cytosolic phospholipase A2 in endothelial cells.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Cell Line; Cytosol; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Flavonoids; Indoles; Isoenzymes; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Protein Kinase Inhibitors; Protein Kinases; Receptors, Purinergic P2; Receptors, Purinergic P2Y1; Receptors, Purinergic P2Y2; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Thapsigargin; Thionucleotides; Tritium; Uridine Triphosphate | 1999 |
Very low density lipoprotein-mediated signal transduction and plasminogen activator inhibitor type 1 in cultured HepG2 cells.
Topics: Antioxidants; Arachidonic Acid; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Hepatocellular; Cholesterol, VLDL; Endothelium, Vascular; Enzyme Inhibitors; Estrenes; Fibrinolysis; Flavonoids; Gallic Acid; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Phosphodiesterase Inhibitors; Phospholipase D; Phosphorylation; Plasminogen Activator Inhibitor 1; Protein Kinase C; Pyrrolidinones; Signal Transduction; Thapsigargin; Tritium; Tumor Cells, Cultured; Tyrosine | 1999 |
Mitogen-activated protein kinase signaling in bovine articular chondrocytes in response to fluid flow does not require calcium mobilization.
Topics: Aggrecans; Animals; Biomechanical Phenomena; Calcium; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Egtazic Acid; Extracellular Matrix Proteins; Flavonoids; Gene Expression; Humans; Lectins, C-Type; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proteoglycans; Signal Transduction; Thapsigargin; Transfection | 2000 |
Extracellular signal-regulated kinase pathway is involved in basic fibroblast growth factor effect on angiotensin II-induced Ca(2+) transient in vascular smooth muscle cell from Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Calcium Signaling; Cell Size; DNA; Enzyme Inhibitors; Fibroblast Growth Factor 2; Flavonoids; Hypertension; In Vitro Techniques; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Protein Biosynthesis; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Thapsigargin | 2000 |
Participation of mitogen-activated protein kinase in thapsigargin- and TPA-induced histamine production in murine macrophage RAW 264.7 cells.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Inhibitors; Flavonoids; Histamine Release; Imidazoles; Macrophages; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Carbachol-stimulated transactivation of epidermal growth factor receptor and mitogen-activated protein kinase in T(84) cells is mediated by intracellular Ca2+, PYK-2, and p60(src).
Topics: Calcium; Carbachol; Cell Line; Chlorides; Colon; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Flavonoids; Fluphenazine; Focal Adhesion Kinase 2; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Quinazolines; Signal Transduction; Thapsigargin; Time Factors; Transcriptional Activation; Tyrphostins | 2000 |
Basal cPLA(2) phosphorylation is sufficient for Ca(2+)-induced full activation of cPLA(2) in A549 epithelial cells.
Topics: Acetophenones; Arachidonic Acid; Benzopyrans; Calcium; Cell Line; Cytosol; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Phospholipases A; Phosphorylation; Protein Kinase C; Tetradecanoylphorbol Acetate; Thapsigargin | 2000 |
Basic fibroblast growth factor stimulates vascular endothelial growth factor release in osteoblasts: divergent regulation by p42/p44 mitogen-activated protein kinase and p38 mitogen-activated protein kinase.
Topics: Animals; Calcimycin; Calcium; Endothelial Growth Factors; Enzyme Inhibitors; Fibroblast Growth Factor 2; Flavonoids; Imidazoles; In Vitro Techniques; Ionophores; Lymphokines; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Thapsigargin; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Expression of 74-kDa histidine decarboxylase protein in a macrophage-like cell line RAW 264.7 and inhibition by dexamethasone.
Topics: Animals; Catalysis; Cell Line; Dexamethasone; Enzyme Activation; Enzyme Induction; Flavonoids; Histamine; Histidine Decarboxylase; Imidazoles; Immunoblotting; Macrophages; Mice; Mitogen-Activated Protein Kinases; Pyridines; Thapsigargin | 2001 |
Smooth muscle cell response to mechanical injury involves intracellular calcium release and ERK1/ERK2 phosphorylation.
Topics: Animals; Arteries; Calcimycin; Calcium; Calcium Channel Blockers; Calmodulin; Cell Division; Cell Movement; Cells, Cultured; DNA; Egtazic Acid; Enzyme Inhibitors; Flavonoids; Fluphenazine; Genistein; Intracellular Fluid; Ionomycin; Ionophores; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Octanols; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Stress, Mechanical; Thapsigargin; Verapamil | 2001 |
Activation of p42/p44 mitogen-activated protein kinase and contraction by prostaglandin F2alpha, ionomycin, and thapsigargin in cat iris sphincter smooth muscle: inhibition by PD98059, KN-93, and isoproterenol.
Topics: Adrenergic beta-Agonists; Animals; Benzylamines; Blotting, Western; Calcium-Transporting ATPases; Cats; Densitometry; Dinoprost; Enzyme Activation; Enzyme Inhibitors; Flavonoids; In Vitro Techniques; Ionomycin; Ionophores; Iris; Isoproterenol; Mitogen-Activated Protein Kinase 1; Muscle Contraction; Muscle, Smooth; Sulfonamides; Thapsigargin | 2001 |
PKC- and ERK-dependent activation of I kappa B kinase by lipopolysaccharide in macrophages: enhancement by P2Y receptor-mediated CaMK activation.
Topics: Animals; Benzylamines; Bridged-Ring Compounds; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Enzyme Inhibitors; Flavonoids; I-kappa B Kinase; I-kappa B Proteins; Imidazoles; Indoles; Lipopolysaccharides; Macrophages; Macrophages, Peritoneal; Mitogen-Activated Protein Kinases; NF-kappa B; Norbornanes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Receptors, Purinergic P2; Sulfonamides; Thapsigargin; Thiocarbamates; Thiones; Time Factors; Transcription Factor RelA; Uridine Triphosphate | 2001 |
Activation of PKC but not of ERK is required for vitamin E-succinate-induced apoptosis of HL-60 cells.
Topics: Apoptosis; Caspase 3; Caspases; Cell Membrane; Cell Nucleus; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Activation; fas Receptor; Flavonoids; HL-60 Cells; Humans; Indoles; Isoenzymes; Lamin Type B; Lamins; Maleimides; Mitogen-Activated Protein Kinases; Nuclear Proteins; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinase C; Protein Kinase C-alpha; Protein Transport; Retinoblastoma Protein; Thapsigargin; Tocopherols; U937 Cells; Vitamin E | 2001 |
Interferon-gamma stimulates the expression of the inducible cAMP early repressor in macrophages through the activation of casein kinase 2. A potentially novel pathway for interferon-gamma-mediated inhibition of gene transcription.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Apigenin; Blotting, Western; Calcimycin; Calcium; Casein Kinase II; Cell Line; Cloning, Molecular; Colforsin; Cyclic AMP; Cyclic AMP Response Element Modulator; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; DNA; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Genetic Vectors; Imidazoles; Indoles; Interferon-gamma; Macrophages; Maleimides; Mice; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Protein Kinase C; Protein Serine-Threonine Kinases; Pyridines; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thapsigargin; Time Factors; Transcription, Genetic; Transcriptional Activation; Tyrphostins | 2003 |
IRAS, the human homologue of Nischarin, prolongs survival of transfected PC12 cells.
Topics: Androstadienes; Anilides; Animals; Annexin A5; Apoptosis; Carrier Proteins; Caspase 3; Caspases; Cell Death; Cell Survival; Chromones; Culture Media, Serum-Free; Flavonoids; Flow Cytometry; Humans; Imidazoline Receptors; Immunoblotting; Intracellular Signaling Peptides and Proteins; Morpholines; Oligopeptides; PC12 Cells; Proteins; Rats; Staurosporine; Thapsigargin; Transfection; Wortmannin | 2003 |
JNK mitogen-activated protein kinase limits calcium-dependent chloride secretion across colonic epithelial cells.
Topics: Amino Acids, Cyclic; Anthracenes; Calcium; Carbachol; Cell Line; Cell Polarity; Chlorides; Cholinergic Agonists; Colon; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Intestinal Mucosa; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Phosphorylation; Potassium; Quinazolines; Thapsigargin; Tyrphostins | 2010 |