pd 98059 and sesquiterpenes

Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Inhibitors; Flavonoids; Hypoxia, Brain; Nerve Growth Factors; Neurites; Neurons; Plant Roots; Plants, Medicinal; Polycyclic Sesquiterpenes; Rats; Rats, Wistar; Sesquiterpenes

Topics: Animals; Antineoplastic Agents; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Mitogen-Activated Protein Kinases; Mitosis; Sea Urchins; Sesquiterpenes; Signal Transduction

Topics: 3T3 Cells; Animals; Anti-Bacterial Agents; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Movement; Cells, Cultured; Cyclin-Dependent Kinases; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Kinetin; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Purines; Rats; Rats, Sprague-Dawley; Receptors, Platelet-Derived Growth Factor; Sesquiterpenes; Time Factors; Tyrosine

Topics: Animals; Cells, Cultured; Diphosphonates; Endothelial Growth Factors; Endothelium, Vascular; Flavonoids; Glycation End Products, Advanced; Humans; Intercellular Signaling Peptides and Proteins; Lymphokines; Neovascularization, Pathologic; NF-kappa B; Polyisoprenyl Phosphates; Promoter Regions, Genetic; Sesquiterpenes; Transcription Factor AP-1; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

Topics: Animals; Bucladesine; Cell Differentiation; Central Nervous System; Dose-Response Relationship, Drug; Drug Synergism; Drugs, Chinese Herbal; Enzyme Inhibitors; Flavonoids; MAP Kinase Signaling System; Neurites; PC12 Cells; Phosphorylation; Polycyclic Sesquiterpenes; Rats; Sesquiterpenes; Staurosporine

Topics: Aorta; Caffeic Acids; Cells, Cultured; Coronary Vessels; Dactinomycin; Dose-Response Relationship, Drug; Flavonoids; Humans; Hydrogen Peroxide; Imidazoles; Interleukin-8; Lipoproteins, LDL; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenylethyl Alcohol; Pyridines; Sesquiterpenes; Time Factors; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

Topics: Active Transport, Cell Nucleus; Animals; Astrocytes; Bradykinin; Cells, Cultured; Chromones; Flavonoids; Gene Expression Regulation; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Morpholines; NF-kappaB-Inducing Kinase; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Sesquiterpenes; Sesquiterpenes, Guaiane; Signal Transduction

Topics: Alkyl and Aryl Transferases; Androstadienes; Anthracenes; Antibodies, Monoclonal; Cells, Cultured; Chemotaxis; Chromones; Class I Phosphatidylinositol 3-Kinases; Farnesyltranstransferase; Flavonoids; Glucose; Humans; Imidazoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Lovastatin; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polyisoprenyl Phosphates; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; ras Proteins; Sesquiterpenes; Sirolimus; TOR Serine-Threonine Kinases; Wortmannin

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alkaloids; Androstadienes; Antineoplastic Agents, Phytogenic; Benzophenanthridines; Cell Differentiation; Cell Proliferation; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; HL-60 Cells; Humans; Indoles; Lactones; Maleimides; Models, Biological; Morpholines; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phenanthridines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Sesquiterpenes; Sesquiterpenes, Guaiane; Signal Transduction; Wortmannin

Topics: Acetophenones; Animals; Astrocytes; Benzopyrans; Bradykinin; Cell Line; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C-delta; Rats; Receptors, Bradykinin; RNA, Messenger; Sesquiterpenes; Sesquiterpenes, Guaiane

Topics: ADAM Proteins; ADAMTS4 Protein; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cartilage, Articular; Cattle; Cells, Cultured; Chondrocytes; Collagenases; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Interleukin-6; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Matrix Metalloproteinase 13; Matrix Metalloproteinase 3; Matrix Metalloproteinases; Metalloendopeptidases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Procollagen N-Endopeptidase; Receptors, Interleukin-6; Sesquiterpenes; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Transcriptional Activation; Up-Regulation

Topics: Alkaloids; Androstadienes; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Line, Tumor; Cell Survival; Enzyme Inhibitors; Flavonoids; Humans; Hydrogen Peroxide; Immunohistochemistry; Indole Alkaloids; Nerve Growth Factor; Neuroblastoma; Neuroprotective Agents; Oxidants; Oxidative Stress; Protein Kinase Inhibitors; Receptor, Nerve Growth Factor; Receptor, trkA; Receptors, Nerve Growth Factor; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes; Wortmannin

Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Arthritis, Rheumatoid; Blotting, Western; Cell Proliferation; Cells, Cultured; Fibroblasts; Flavonoids; Humans; Immunohistochemistry; Interleukin-17; Interleukin-1beta; Interleukin-6; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Interleukin-6; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes; Signal Transduction; STAT3 Transcription Factor; Stimulation, Chemical; Synovial Membrane; Tumor Necrosis Factor-alpha

Topics: Anti-Inflammatory Agents; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Hyaluronic Acid; Imidazoles; Matrix Metalloproteinase 1; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Oligosaccharides; p38 Mitogen-Activated Protein Kinases; Periodontal Ligament; Pyridines; Sesquiterpenes; Sesquiterpenes, Guaiane; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2

Topics: Amino Acid Chloromethyl Ketones; Anthracenes; Antithrombins; Blotting, Western; Butadienes; Cell Line; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Enzyme Inhibitors; Flavonoids; Gene Expression; Glycoproteins; Hirudins; Humans; JNK Mitogen-Activated Protein Kinases; Lipoproteins, VLDL; Macrophages; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; Nitrobenzenes; Reverse Transcriptase Polymerase Chain Reaction; Sesquiterpenes; Signal Transduction; Sulfonamides; Thrombin; Time Factors

Topics: Aristolochia; Blotting, Western; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Flavonoids; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Structure; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plant Stems; Sesquiterpenes; Signal Transduction

Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcuma; Dacarbazine; Down-Regulation; Drug Resistance, Neoplasm; Flavonoids; Glia Maturation Factor; Glioblastoma; Humans; Inhibitor of Apoptosis Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; RNA Interference; RNA, Small Interfering; Sesquiterpenes; Survivin; Temozolomide

Topics: Anthracenes; Apoptosis; bcl-X Protein; Caffeic Acids; Cell Line, Tumor; Chromones; Flavonoids; Gene Expression Regulation, Developmental; Hematopoiesis; Humans; Macrophage Colony-Stimulating Factor; Macrophages; MAP Kinase Signaling System; Monocytes; Morpholines; NF-kappa B; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Sesquiterpenes; Signal Transduction; Tetradecanoylphorbol Acetate

Topics: AMP-Activated Protein Kinases; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Lung Neoplasms; MAP Kinase Signaling System; Metformin; Phosphorylation; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Small Interfering; Sesquiterpenes; Sp1 Transcription Factor

Topics: Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Flavonoids; GAP-43 Protein; Heterocyclic Compounds, 3-Ring; MAP Kinase Signaling System; Mice; Nerve Growth Factor; Neurites; Phosphorylation; Primary Cell Culture; Rats; Sesquiterpenes; Sesquiterpenes, Guaiane

Topics: A549 Cells; Animals; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Female; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; Lactones; Luminescent Measurements; Lung Neoplasms; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Promoter Regions, Genetic; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Sesquiterpenes; Sp1 Transcription Factor; STAT3 Transcription Factor; Transplantation, Heterologous

Topics: Alkaloids; Animals; Antioxidant Response Elements; Apoptosis; Catalase; Cell Cycle; Chromones; Flavonoids; Gene Expression Regulation; Glutathione Peroxidase; Imidazoles; Kelch-Like ECH-Associated Protein 1; Lipid Peroxides; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; NF-E2-Related Factor 2; NIH 3T3 Cells; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Radiation-Protective Agents; Reactive Oxygen Species; Sesquiterpenes; Signal Transduction; Superoxide Dismutase; X-Rays