pd 98059 and pyrazolanthrone

Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

Topics: Animals; Apoptosis; Dioxoles; Heme Oxygenase-1; Hydrogen Peroxide; Lignans; NF-E2-Related Factor 2; PC12 Cells; Rats; Seedlings; Sesamum

Topics: Animals; Cells, Cultured; Coumarins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flowers; Mammea; Mice; Molecular Structure; Nitric Oxide Synthase Type II; Stereoisomerism; Structure-Activity Relationship

Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

Topics: Animals; Cell Line; Dimerization; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Resveratrol; Signal Transduction; Stilbenes; Structure-Activity Relationship

Topics: Animals; Anti-Inflammatory Agents; Diarylheptanoids; Janus Kinase 2; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Sepsis; STAT3 Transcription Factor

Topics: Activating Transcription Factor 2; Animals; Anthracenes; Arthritis, Experimental; Cells, Cultured; Collagenases; Cyclic AMP Response Element-Binding Protein; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Interleukin-1; Isoenzymes; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Matrix Metalloproteinase 13; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Rats; Rats, Inbred Lew; RNA, Messenger; Synovial Membrane; Transcription Factor AP-1; Transcription Factors

Topics: Animals; Anthracenes; Blotting, Western; Cell Line; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Genetic Vectors; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Monocytes; Mutation; p38 Mitogen-Activated Protein Kinases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha

Topics: Administration, Topical; Anthracenes; Anti-Inflammatory Agents; Apoptosis; Bronchi; Budesonide; Caspase 3; Caspases; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Glucocorticoids; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Transforming Growth Factor beta

Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Adenocarcinoma; Anthracenes; Apoptosis; Cell Division; Cell-Free System; Culture Media, Serum-Free; DNA-Binding Proteins; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; ets-Domain Protein Elk-1; Flavonoids; Humans; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Phosphorylation; Plant Extracts; Prostatic Neoplasms; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Seeds; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Transcription Factor AP-1; Transcription Factors; Tumor Cells, Cultured; Vitis

Topics: Anthracenes; Cycloheximide; Dactinomycin; Fibroblast Growth Factor 2; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Muscle, Smooth, Vascular; Proto-Oncogene Proteins c-sis; Pyridines; RNA, Messenger

Topics: Amyloid beta-Peptides; Anthracenes; Cells, Cultured; Chemokines; Cyclic AMP Response Element-Binding Protein; Cytokines; DNA-Binding Proteins; Early Growth Response Protein 1; Flavonoids; Gene Expression Regulation; Humans; Immediate-Early Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Nucleic Acid Heteroduplexes; Peptide Fragments; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; RNA, Messenger; RNA, Small Interfering; Transcription Factor AP-1; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured

Topics: Adaptor Proteins, Signal Transducing; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Anthracenes; Carrier Proteins; Dimerization; Epidermal Growth Factor; ErbB Receptors; Flavonoids; Humans; Hybrid Cells; Imidazoles; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; Mice; Mitogen-Activated Protein Kinases; Neurons; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Protein Structure, Tertiary; Proteins; Pyridines; Rats; Signal Transduction

Topics: Animals; Anthracenes; Apoptosis; Arsenites; Cell Division; Cells, Cultured; DNA; Epithelial Cells; Flavonoids; GADD45 Proteins; Intracellular Signaling Peptides and Proteins; Lung; Mitogen-Activated Protein Kinases; Proteins; Rats; Signal Transduction; Transcription Factor AP-1

Topics: Anthracenes; Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cell Survival; Cytoprotection; Dose-Response Relationship, Radiation; Enzyme Activation; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Korea; Lysophospholipids; Melanocytes; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Pyridines; Sphingosine; Ultraviolet Rays

Topics: Androstadienes; Anthracenes; Apoptosis; Butadienes; Cell Survival; Chromones; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Hydrogen Peroxide; Imidazoles; Insulin-Like Growth Factor I; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Kinetics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oxazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptor, IGF Type 1; RNA, Messenger; Wortmannin

Topics: Acetylcysteine; Anthracenes; Cells, Cultured; Chemokine CXCL1; Chemokines, CXC; Cysteine Proteinase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Humans; I-kappa B Proteins; Imidazoles; Intercellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Leupeptins; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Umbilical Veins

Topics: Anthracenes; Apoptosis; Blotting, Western; Cell Division; Cell Survival; Cells, Cultured; Ceramides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Helicobacter pylori; Humans; JNK Mitogen-Activated Protein Kinases; Lipid Metabolism; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Structure, Tertiary; Signal Transduction; Sphingomyelin Phosphodiesterase; Stomach; Time Factors

Topics: Animals; Annexin A5; Anthracenes; Apoptosis; Brain; Carbofuran; Cell Survival; Cells, Cultured; Endothelium, Vascular; Flavonoids; Flow Cytometry; Imidazoles; Mice; Microcirculation; Microscopy, Electron; Mitogen-Activated Protein Kinases; Pesticides; Pyridines; Signal Transduction; Time Factors

Topics: 3' Untranslated Regions; Animals; Anisomycin; Anthracenes; Butadienes; Cell Line; Cricetinae; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Heterogeneous-Nuclear Ribonucleoproteins; Imidazoles; Mitogen-Activated Protein Kinase Kinases; Nitriles; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Pyridines; Receptors, Adrenergic, beta; RNA Stability; Signal Transduction

Topics: Animals; Anthracenes; Clone Cells; Dinoprost; Flavonoids; Heat-Shock Proteins; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Molecular Chaperones; Neoplasm Proteins; Osteoblasts; Phosphorylation

Topics: Alzheimer Disease; Animals; Anisomycin; Anthracenes; Brain; Cell Line; Cell Line, Tumor; COS Cells; Down-Regulation; Enzyme Inhibitors; Estradiol; Flavonoids; Genetic Vectors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Humans; Immunohistochemistry; In Vitro Techniques; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Neurons; Oxidoreductases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Retroviridae; RNA, Small Interfering; Serine; tau Proteins; Temperature; Threonine; Time Factors; Tumor Suppressor Proteins; Two-Hybrid System Techniques; Tyrosine; WW Domain-Containing Oxidoreductase

Topics: Angiotensin II; Animals; Anthracenes; Blotting, Western; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Flavonoids; Genistein; Imidazoles; Kidney; Losartan; Mice; Microscopy, Fluorescence; Onium Compounds; PAX2 Transcription Factor; Phosphorylation; Plasmids; Pyridines; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Transcription Factors; Tyrphostins; Up-Regulation

Topics: Androstadienes; Animals; Animals, Newborn; Anthracenes; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Flavonoids; Genistein; Imidazoles; Male; Matrix Metalloproteinase 2; Mice; Mice, Knockout; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Pyridines; Skin; Tenascin; Wortmannin

Topics: Alkyl and Aryl Transferases; Androstadienes; Anthracenes; Antibodies, Monoclonal; Cells, Cultured; Chemotaxis; Chromones; Class I Phosphatidylinositol 3-Kinases; Farnesyltranstransferase; Flavonoids; Glucose; Humans; Imidazoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Lovastatin; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polyisoprenyl Phosphates; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; ras Proteins; Sesquiterpenes; Sirolimus; TOR Serine-Threonine Kinases; Wortmannin

Topics: Amphetamine; Animals; Anthracenes; Antimanic Agents; Blotting, Western; Carbamazepine; Cell Line; Cell Survival; Chloramphenicol O-Acetyltransferase; Corticosterone; Dose-Response Relationship, Drug; Flavonoids; Gene Expression Regulation, Enzymologic; Imidazoles; Indoles; Inositol; Lithium; Maleimides; Protein Kinase C; Protein Kinase C-alpha; Pyridines; Receptors, Glucocorticoid; Tamoxifen; Tetradecanoylphorbol Acetate; Valproic Acid

Topics: Animals; Anthracenes; Burns; Enzyme Inhibitors; Female; Flavonoids; Imidazoles; Immunophenotyping; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Tumor Necrosis Factor-alpha

Topics: Animals; Anthracenes; Bradykinin; Dactinomycin; Dexamethasone; Electromyography; Enzyme Inhibitors; Flavonoids; Imidazoles; In Vitro Techniques; Interleukin-4; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Pyridines; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Trachea

Topics: Animals; Anthracenes; Aorta; Cell Division; Cells, Cultured; Chromones; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Enzyme Induction; Flavonoids; Heme Oxygenase (Decyclizing); Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Mice; Mice, Inbred C57BL; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Nitric Oxide; Organ Specificity; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protoporphyrins; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Simvastatin

Topics: Androstadienes; Animals; Anthracenes; Cell Line; Cell Movement; Cell Survival; Chemokine CCL4; Chemotaxis; Chromones; Complement C5a; Diterpenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Macrophage Inflammatory Proteins; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Morpholines; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Wortmannin

Topics: Anthracenes; Antigens, CD; Biological Transport; Cell Differentiation; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dendritic Cells; Dextrans; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Fluorescein-5-isothiocyanate; HLA-DR Antigens; Humans; Imidazoles; Interleukin-12; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Monocytes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Protein Subunits; Pyridines; Tumor Necrosis Factor-alpha; Up-Regulation

Topics: Adrenergic alpha-1 Receptor Agonists; Animals; Anthracenes; Aorta, Thoracic; Bacterial Proteins; Benzopyrans; Butadienes; Catheterization; Cell Division; Dipeptides; ErbB Receptors; Flavonoids; Glycine; Hydroxamic Acids; Imidazoles; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitriles; Organ Culture Techniques; Phenylephrine; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Quinazolines; Rats; Receptors, Adrenergic, alpha-1; Thrombin; Tyrphostins

Topics: Anthracenes; Cells, Cultured; Cyclooxygenase 2; Endometriosis; Endometrium; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; Hydrogen Peroxide; Interleukin-1; Interleukin-6; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Signal Transduction; Stromal Cells; Tumor Necrosis Factor-alpha

Topics: Animals; Anthracenes; Extracellular Signal-Regulated MAP Kinases; Flavonoids; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Male; MAP Kinase Signaling System; Pneumonia; Rats; Rats, Sprague-Dawley; Treatment Outcome

Topics: Anthracenes; Aorta; Arteriosclerosis; Cell Adhesion; Depression, Chemical; Endothelial Cells; Endothelium, Vascular; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Inflammation; Intercellular Adhesion Molecule-1; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; NADPH Oxidases; Neutrophils; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Recombinant Fusion Proteins; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Transcription Factor AP-1; Transcription, Genetic; Transduction, Genetic; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

Topics: Anthracenes; Apoptosis; Caspase 3; Caspases; Cytokines; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Humans; Imidazoles; Immunotoxins; Jurkat Cells; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Mycotoxins; Phosphorylation; Pyridines; T-Lymphocytes; Trichothecenes

Topics: Anthracenes; Antigens, CD; Antigens, Surface; B7-2 Antigen; Blotting, Western; Cadherins; CD83 Antigen; Enzyme Inhibitors; Female; Flavonoids; Flow Cytometry; Humans; Imidazoles; Immunoglobulins; Irritants; Langerhans Cells; Lectins, C-Type; Mannose-Binding Lectins; MAP Kinase Signaling System; Membrane Glycoproteins; Mitogen-Activated Protein Kinases; Nickel; Pyridines; Receptors, CCR7; Receptors, Chemokine; Tumor Necrosis Factor-alpha

Topics: Actins; Anthracenes; Cell Differentiation; Cell Line; Cell Movement; Down-Regulation; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Fibronectins; Flavonoids; Humans; Imidazoles; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Keratins; Kidney Tubules, Proximal; p38 Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction

Topics: Animals; Anthracenes; Aorta; Arteriosclerosis; Blotting, Western; Cells, Cultured; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Hypertrophy; Leptin; Leucine; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; STAT3 Transcription Factor; Time Factors; Trans-Activators; Tyrphostins

Topics: Anthracenes; Apoptosis; Bupleurum; Chromatography, Liquid; Drugs, Chinese Herbal; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Humans; Imidazoles; Immunoblotting; Keratin-8; Keratins; Mass Spectrometry; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Pyridines; Tumor Cells, Cultured

Topics: 3T3 Cells; Animals; Anthracenes; Enzyme Inhibitors; Flavonoids; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Osteoblasts; Phosphorylation; Skull; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A

Topics: Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Anthracenes; Aspartic Acid Endopeptidases; Cell Line, Tumor; Cell Survival; Endopeptidases; Enzyme Inhibitors; Flavonoids; Glioma; Humans; Interleukin-1; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Solubility

Topics: Androstadienes; Anthocyanins; Anthracenes; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspases; Cell Survival; Cytochromes c; DNA, Mitochondrial; Dose-Response Relationship, Drug; Fas Ligand Protein; Flavonoids; Flowers; Hibiscus; HL-60 Cells; Humans; Imidazoles; Membrane Glycoproteins; p38 Mitogen-Activated Protein Kinases; Plant Extracts; Proto-Oncogene Proteins c-jun; Pyridines; RNA, Messenger; Time Factors; Wortmannin

Topics: Analysis of Variance; Animals; Anthracenes; Apoptosis; Blotting, Western; Cells, Cultured; DNA Fragmentation; Flavonoids; Imidazoles; Mice; Microscopy, Electron, Transmission; Mitogen-Activated Protein Kinases; Mollusca; Peptides; Pyridines; Signal Transduction; Thymus Gland; Ultraviolet Rays

Topics: Anthracenes; Apoptosis; Cell Line; Cell Nucleus; Cisplatin; DNA Damage; Doxycycline; Dual-Specificity Phosphatases; Flavonoids; Gene Expression; Humans; JNK Mitogen-Activated Protein Kinases; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Phosphatases; Mutation; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Peptides; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Tyrosine Phosphatases; Signal Transduction; Transfection; Ultraviolet Rays

Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Cell Differentiation; Cell Line, Transformed; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Stem Cells; Telencephalon; Tumor Suppressor Protein p53

Topics: Acetylcysteine; Anthracenes; Cell Line, Tumor; Cell Survival; Epithelial Cells; Flavonoids; Gene Expression Regulation; Humans; Interleukin-8; Motorcycles; NF-kappa B; Proline; RNA, Messenger; Thiocarbamates; Vehicle Emissions

Topics: Adenosine Triphosphate; Animals; Anthracenes; Astrocytes; Brain Ischemia; Cell Culture Techniques; Cell Death; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glucose; Imidazoles; L-Lactate Dehydrogenase; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Molsidomine; Nitric Oxide Donors; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Pyridines; Rats; Rats, Sprague-Dawley

Topics: Animals; Anthracenes; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Transformed; Cell Proliferation; Cell Transformation, Viral; Cells, Cultured; Erythropoietin; Extracellular Signal-Regulated MAP Kinases; Flavonoids; JNK Mitogen-Activated Protein Kinases; Leukemia, Experimental; MAP Kinase Kinase Kinases; Mice; Retroviridae Infections; Signal Transduction; Spleen Focus-Forming Viruses; Transcription Factor AP-1; Tumor Cells, Cultured; Tumor Virus Infections

Topics: Anthracenes; Antibiotics, Antineoplastic; Antioxidants; Blotting, Western; Carbazoles; Carvedilol; Catecholamines; Cell Line; Doxorubicin; Enzyme Activation; Flavonoids; Humans; Imidazoles; Imidazolines; Janus Kinase 1; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinases; Mitogen-Activated Protein Kinases; Myocytes, Cardiac; NADPH Oxidases; p38 Mitogen-Activated Protein Kinases; Propanolamines; Protein-Tyrosine Kinases; Pyridines; Razoxane

Topics: Anthracenes; Chondrocytes; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Interleukin-1; Mitogen-Activated Protein Kinases; Pyridines; RNA, Messenger; Signal Transduction

Topics: Aniline Compounds; Anisomycin; Anthracenes; Cell Line, Tumor; Cytokines; Dose-Response Relationship, Drug; Eukaryotic Initiation Factor-4E; Flavonoids; Humans; Imidazoles; Lipopolysaccharides; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphorylation; Purines; Pyridines; RNA, Messenger; Shiga Toxin 1; Time Factors

Topics: Algorithms; Anthracenes; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; Flavonoids; Genes, bcl-2; Genes, p53; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Silymarin; Ultraviolet Rays

Topics: Adolescent; Adult; Anthracenes; Blood Proteins; Culture Media, Conditioned; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Keloid; Keratinocytes; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Pyridines; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta2; Transforming Growth Factor beta3

Topics: Animals; Anthracenes; Blotting, Western; Bone Marrow Cells; Cell Movement; Cell Proliferation; Cells, Cultured; Chymases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Imidazoles; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Smad3 Protein; Transforming Growth Factor beta; Tryptases; Up-Regulation

Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Anthracenes; Blotting, Western; CCAAT-Enhancer-Binding Protein-beta; Cell Differentiation; Cell Line; Enzyme Induction; Flavonoids; Humans; Imidazoles; Interferon-gamma; Mitogen-Activated Protein Kinases; Monocytes; Protein Kinase Inhibitors; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; STAT1 Transcription Factor; Tetradecanoylphorbol Acetate

Topics: 4-Butyrolactone; Animals; Anthracenes; Blotting, Western; Cell Cycle; Cell Proliferation; Cells, Cultured; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Dose-Response Relationship, Drug; Enzyme Activation; Flavonoids; Imidazoles; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Pyridines; Rats; Rats, Wistar; Reactive Oxygen Species; Retinoblastoma Protein

Topics: Animals; Anthracenes; Cell Line; Enzyme Inhibitors; Flavonoids; Heat-Shock Proteins; Imidazoles; Intracellular Signaling Peptides and Proteins; Mice; Mitogen-Activated Protein Kinases; Osteoblasts; Phosphorylation; Prostaglandin D2; Protein Kinases; Protein Serine-Threonine Kinases

Topics: Anthracenes; Blotting, Western; Cells, Cultured; Dose-Response Relationship, Drug; Emodin; Fibroblasts; Flavonoids; Humans; Imidazoles; Infant, Newborn; JNK Mitogen-Activated Protein Kinases; Luciferases; Male; Matrix Metalloproteinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promoter Regions, Genetic; Pyridines; Rheum; Transcription Factor AP-1; Transfection; Tumor Necrosis Factor-alpha

Topics: Anthracenes; Apoptosis; Blotting, Western; Cell Line, Tumor; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; p38 Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Tumor Necrosis Factor-alpha

Topics: Anthracenes; Apoptosis; Blotting, Western; Butyrates; Caspase 8; Cell Line, Tumor; Chromosomes, Human, Pair 21; Chromosomes, Human, Pair 8; Drug Administration Schedule; Drug Therapy, Combination; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Histone Deacetylase Inhibitors; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Leukemia, Myeloid, Acute; Mannose; p38 Mitogen-Activated Protein Kinases; Pyridines; Translocation, Genetic

Topics: Anthracenes; Bone and Bones; Calcium; Calcium Signaling; Cations, Divalent; Cyclooxygenase 2; Dinoprostone; Estrenes; Fibroblasts; Flavonoids; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Pyrrolidinones; Receptors, Calcium-Sensing; RNA, Messenger; Type C Phospholipases

Topics: Actins; Alanine Transaminase; Animals; Anthracenes; Carbon Tetrachloride Poisoning; Extracellular Signal-Regulated MAP Kinases; Fibrinogen; Flavonoids; Humans; JNK Mitogen-Activated Protein Kinases; Liver; Liver Cirrhosis; Mice; Phosphorylation; Proto-Oncogene Proteins c-jun; Rats; Signal Transduction; Tissue Inhibitor of Metalloproteinase-1; Transcription Factors; Transcription, Genetic

Topics: Animals; Anthracenes; Cells, Cultured; Dose-Response Relationship, Drug; Exportin 1 Protein; Flavonoids; HMGB1 Protein; Humans; Hydrogen Peroxide; Karyopherins; Macrophages; Mice; Monocytes; Oxidative Stress; Reactive Oxygen Species; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship; Time Factors

Topics: Animals; Anthracenes; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chromones; Enzyme Inhibitors; Flavonoids; Imidazoles; Interleukin-1beta; Mice; Morpholines; Nitric Oxide Synthase Type II; Organ of Corti; Phosphatidylinositol 3-Kinases; Pyridines; Signal Transduction; Transcriptional Activation; Up-Regulation

Topics: Animals; Anthracenes; Calcium-Calmodulin-Dependent Protein Kinases; Ceruletide; Cytokines; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pancreas, Exocrine; Pyridines; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha

Topics: Androgens; Anthracenes; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; Interleukin-6; Male; p38 Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Pyridines; Ritodrine

Topics: Amides; Anthracenes; Aorta; Blotting, Western; Boron Compounds; cdc42 GTP-Binding Protein; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Endothelial Cells; Enzyme Activation; Flavonoids; Humans; Imidazoles; Leucine; Mitogen-Activated Protein Kinases; Phosphorylation; Pravastatin; Protein Transport; Pyridines; rac1 GTP-Binding Protein; Thrombomodulin; Time Factors; Tumor Necrosis Factor-alpha

Topics: Acetophenones; Animals; Anthracenes; Benzamides; Chromones; Dioxoles; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Heparin-binding EGF-like Growth Factor; Hepatocytes; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Morpholines; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Onium Compounds; Peptides; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quinazolines; rac1 GTP-Binding Protein; Rats; Reactive Oxygen Species; Transforming Growth Factor beta; Tyrphostins; Up-Regulation

Topics: Anthracenes; Cell Proliferation; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Fibroblasts; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Keloid; Low-Level Light Therapy; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Transcription Factor AP-1; Transforming Growth Factor beta1

Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Anthracenes; Antineoplastic Agents; Antioxidants; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Estradiol; Extracellular Signal-Regulated MAP Kinases; Female; Flavanones; Flavonoids; Glycosides; Humans; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinases; Molecular Structure; Phosphoproteins; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; Quercetin; Reactive Oxygen Species; Signal Transduction; Structure-Activity Relationship; Transfection

Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anthracenes; Apoptosis; Astrocytoma; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dicumarol; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; Ion Channels; JNK Mitogen-Activated Protein Kinases; Necrosis; Niflumic Acid; Nitrobenzoates; Osmolar Concentration; Pyridines; Rats; Taurine

Topics: Animals; Anthracenes; Blotting, Western; Cell Line; Extracellular Signal-Regulated MAP Kinases; Flavanones; Flavones; Flavonoids; Gene Expression Regulation, Enzymologic; Inhibitory Concentration 50; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Plant Extracts; Proto-Oncogene Proteins c-jun; Quercetin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Scutellaria baicalensis; Teichoic Acids

Topics: Animals; Anthracenes; Calcium Signaling; Cell Division; Disease Models, Animal; Femoral Artery; Flavonoids; Hyperplasia; Male; Mice; Mice, Inbred Strains; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Plasminogen Activator Inhibitor 1; Tunica Intima; Urokinase-Type Plasminogen Activator

Topics: Adult; Aged; Anthracenes; Arthritis, Rheumatoid; Basigin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Female; Flavonoids; Humans; Lymphocytes; Macrophages; Male; Middle Aged; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; Osteoarthritis; Phosphoinositide-3 Kinase Inhibitors; Polymerase Chain Reaction; Signal Transduction; Synovial Membrane; Vascular Endothelial Growth Factor A; Young Adult

Topics: Acetaldehyde; Animals; Anthracenes; Blotting, Western; Caspase 3; Cell Nucleus; Cells, Cultured; Ethanol; Flavonoids; Hepatocytes; Histones; Imidazoles; Male; Mitogen-Activated Protein Kinase Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Serine

Topics: Animals; Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Cell Line, Tumor; Electrophoretic Mobility Shift Assay; Flavonoids; Gardenia; Glioma; Glucosides; Imidazoles; Immunoblotting; Iridoid Glucosides; Iridoids; Keratolytic Agents; Masoprocol; Mitogen-Activated Protein Kinases; Molecular Structure; Nerve Growth Factor; NF-kappa B; Peptide Fragments; Pyridines; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factor AP-1; Transcriptional Activation

Topics: Anthracenes; Antineoplastic Agents, Phytogenic; Apoptosis; Benzothiazoles; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Tumor; Cinnamomum aromaticum; Enzyme Inhibitors; Flavonoids; Humans; JNK Mitogen-Activated Protein Kinases; Phytotherapy; Plant Extracts; Toluene

Topics: Anthracenes; Apoptosis; Calcium Signaling; Caspase 3; Cell Line, Tumor; Cell Survival; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Preservatives, Pharmaceutical; Protein Kinase Inhibitors; Pyridines; Stomach Neoplasms; Thimerosal; Time Factors

Topics: Aged; Anthracenes; Bone Diseases; Cell Differentiation; Core Binding Factor Alpha 1 Subunit; Female; Flavonoids; Histone Acetyltransferases; Humans; Leptin; Ligaments, Articular; Male; Middle Aged; Mitogen-Activated Protein Kinase 3; Models, Biological; Nuclear Receptor Coactivator 1; STAT3 Transcription Factor; Thoracic Diseases; Transcription Factors

Topics: Anthracenes; Cell Line, Tumor; Colonic Neoplasms; Enzyme Inhibitors; Enzyme Precursors; Factor VII; Flavonoids; Humans; Imidazoles; MAP Kinase Signaling System; Matrix Metalloproteinase 7; Metalloendopeptidases; Pyridines; Thromboplastin

Topics: Anthracenes; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Division; Cell Line, Tumor; Chromones; Drug Screening Assays, Antitumor; Drug Synergism; Flavonoids; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Imidazoles; Leukemia; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Monocytes; Morpholines; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Pyridines; U937 Cells

Topics: Adenine; Anthracenes; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Blotting, Western; Cadaverine; Diterpenes; Diterpenes, Kaurane; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Flow Cytometry; HeLa Cells; Humans; Imidazoles; Isodon; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Microtubule-Associated Proteins; p38 Mitogen-Activated Protein Kinases; Polyenes; Polyunsaturated Alkamides; Pyridines; ras Proteins

Topics: Anthracenes; Bacterial Proteins; Blotting, Western; DNA; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Interleukin-1beta; Interleukin-6; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Monocytes; Mycoplasma genitalium; NF-kappa B; Protein Binding; Pyridines; Pyrrolidines; Thiocarbamates; Time Factors; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

Topics: Anthracenes; Antioxidants; Apoptosis; Cell Line, Tumor; Central Nervous System Stimulants; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Methamphetamine; Neuroblastoma; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Vitamin E

Topics: Amino Acid Transport System A; Amino Acid Transport Systems; Amino Acids; Androstadienes; Animals; Anthracenes; Cell Line; Chloroquine; Cycloheximide; Dactinomycin; Flavonoids; Insulin; Insulin Antagonists; Muscle, Skeletal; Osmotic Pressure; Protein Synthesis Inhibitors; Rats; Up-Regulation; Wortmannin

Topics: Anthracenes; Blotting, Western; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Dexamethasone; Electrophoretic Mobility Shift Assay; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Models, Biological; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Time Factors; Transcription Factor AP-1

Topics: Animals; Anthracenes; Chromones; Female; Flavonoids; Interleukin-10; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Morpholines; Placenta; Pregnancy; Pregnancy, Animal; Spleen; Thy-1 Antigens; Toll-Like Receptor 2; Toll-Like Receptor 4

Topics: Amino Acid Sequence; Anthracenes; Argonaute Proteins; Arsenites; Blotting, Western; Cell Line; Eukaryotic Initiation Factor-2; Flavonoids; Glutathione Transferase; Humans; Imidazoles; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Mass Spectrometry; Microscopy, Confocal; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Pyridines; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Sodium Compounds

Topics: Anthracenes; Cathepsin B; Cathepsin L; Cathepsins; Caveolin 1; Cells, Cultured; Cysteine Endopeptidases; Dipeptides; Fibroblasts; Flavonoids; Gingiva; Humans; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Periodontitis; Phosphorylation; Protease Inhibitors; Protein Kinase Inhibitors; Receptors, Interleukin-6; Recombinant Proteins; RNA Interference; RNA, Small Interfering; Signal Transduction; Time Factors; Transcription Factor AP-1; Transfection; Up-Regulation

Topics: Animals; Animals, Newborn; Anthracenes; Becaplermin; Cell Line; Dose-Response Relationship, Drug; Drug Synergism; Fibroblast Growth Factor 2; Flavonoids; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 3; Models, Biological; Osteoblasts; Phosphorylation; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Receptor, Platelet-Derived Growth Factor beta; Tyrphostins; Vascular Endothelial Growth Factor A

Topics: Anthracenes; Antigens, CD; B7-H1 Antigen; Carcinoma, Transitional Cell; Cell Line, Tumor; Chromones; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharide Receptors; Lipopolysaccharides; MAP Kinase Signaling System; Morpholines; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Pyridines; Toll-Like Receptor 4; Up-Regulation; Urinary Bladder Neoplasms

Topics: Acetophenones; Adrenergic alpha-1 Receptor Antagonists; Anthracenes; Aorta; Apoptosis; Benzothiazoles; Cells, Cultured; Culture Media, Serum-Free; Dioxanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Mitochondria; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Prazosin; Pyridines; Reactive Oxygen Species; Receptors, Adrenergic, alpha-1; Time Factors; Toluene; Tumor Suppressor Protein p53

Topics: Animals; Anthracenes; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; MAP Kinase Signaling System; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Schwann Cells

Topics: Anthracenes; Cell Line, Tumor; Cytotoxicity, Immunologic; Flavonoids; Gene Expression Regulation, Neoplastic; GPI-Linked Proteins; Humans; Intercellular Signaling Peptides and Proteins; Interleukin-18; Jurkat Cells; Leukemia; Mitogen-Activated Protein Kinases

Topics: Anthracenes; Base Sequence; Cell Line, Tumor; Chromones; Cytochrome P450 Family 7; Elafin; Enzyme Activation; Estradiol; Estrogens; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; MAP Kinase Signaling System; Molecular Sequence Data; Morpholines; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Pyridines; Steroid Hydroxylases

Topics: Animals; Anthracenes; Antiviral Agents; Arginase; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; GC Rich Sequence; Imidazoles; Interferon-gamma; Interleukin-10; Interleukin-12; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type II; Oligodeoxyribonucleotides; p38 Mitogen-Activated Protein Kinases; Pyridines; Up-Regulation

Topics: Aggrecans; Animals; Anthracenes; Apoptosis; Benzamides; Cytokine TWEAK; Enzyme Induction; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Extracellular Matrix; Flavonoids; Immunoenzyme Techniques; Intervertebral Disc; Matrix Metalloproteinase 3; Mice; Mice, Inbred C57BL; Recombinant Proteins; Signal Transduction; Tissue Culture Techniques; Tumor Necrosis Factor-alpha; Tumor Necrosis Factors; Up-Regulation

Topics: Animals; Anthracenes; Binding Sites; Carcinoma; Cell Line; Cell Line, Tumor; Cottontail rabbit papillomavirus; Disease Models, Animal; DNA Mutational Analysis; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase 3; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Pyridines; Rabbits; Signal Transduction; Transcription Factor AP-1; Transcription Factors; Viral Proteins

Topics: Anthracenes; Anti-Inflammatory Agents; Benzophenanthridines; Cell Line; Curcumin; Enzyme Activation; Epithelial Cells; Esophagus; Flavonoids; Humans; Hydrogen-Ion Concentration; Imidazoles; Interleukin-6; Interleukin-8; Mitogen-Activated Protein Kinases; Mucous Membrane; NF-kappa B; Peptides; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Telomerase; Time Factors; Transcription, Genetic; Up-Regulation

Topics: Androstadienes; Anthracenes; Cell Proliferation; Cells, Cultured; Dexamethasone; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glucocorticoids; Humans; Lung; MAP Kinase Kinase 4; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Signal Transduction; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Wortmannin

Topics: Androstadienes; Animals; Anthracenes; Cell Line, Transformed; Cisplatin; Coculture Techniques; Cytokines; Cytotoxicity, Immunologic; Flavonoids; Inflammation Mediators; Macrophage Activation; Macrophages, Peritoneal; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Nitric Oxide; Signal Transduction; Toll-Like Receptor 2; Toll-Like Receptor 4; Wortmannin

Topics: Anthracenes; Cell Line; Chromones; Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Flavonoids; Genes, Reporter; Humans; Hypothalamus; Imidazoles; Isoquinolines; Morpholines; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyridines; Regulatory Elements, Transcriptional; Sequence Deletion; Sulfonamides; Transfection

Topics: Anthracenes; Blotting, Western; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Flavonoids; Humans; Imidazoles; Infant, Newborn; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Mitogen-Activated Protein Kinases; Plant Growth Regulators; Pyridines; Skin; Ultraviolet Rays; Zeatin

Topics: Allopurinol; Anthracenes; Blotting, Western; Cadmium; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; Liver; NADPH Oxidases; Onium Compounds; Phosphorylation; Potassium Cyanide; Pyridines; Signal Transduction; STAT3 Transcription Factor; Sulfones

Topics: Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Arecoline; Cheek; Cholinergic Agonists; Connective Tissue Growth Factor; Curcumin; Endothelial Cells; Epithelial Cells; Fibroblasts; Flavonoids; Humans; Imidazoles; Mouth Mucosa; Nitriles; Oral Submucous Fibrosis; Pyridines; Sulfones

Topics: Aminoquinolines; Animals; Anthracenes; Antigens, CD; Cytotoxicity, Immunologic; Embryo Loss; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Imiquimod; Interferon-gamma; Killer Cells, Natural; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred NOD; Poly I-C; Pregnancy; T-Lymphocytes; Toll-Like Receptor 3; Toll-Like Receptor 7; Tumor Necrosis Factor-alpha; Uterus

Topics: Anthracenes; Cadmium; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Fibroblasts; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lung; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Pyridines

Topics: Acetaminophen; Animals; Anthracenes; Cell Line; Cytochrome P-450 CYP1A2 Inhibitors; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; Indomethacin; Interleukin-1beta; Lipopolysaccharides; Macrophages; MAP Kinase Kinase 1; MAP Kinase Kinase 4; Mice; p38 Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Pyridines; Signal Transduction; Theophylline; Tumor Necrosis Factor-alpha

Topics: Anthracenes; Antibodies, Monoclonal; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Chemokine CCL5; Chemotaxis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Focal Adhesion Protein-Tyrosine Kinases; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Phosphorylation; Protein Multimerization; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Surface Plasmon Resonance; Syndecan-1; Syndecan-4

Topics: Adaptor Proteins, Signal Transducing; Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Kidney Neoplasms; Leupeptins; Mitogen-Activated Protein Kinase 8; p38 Mitogen-Activated Protein Kinases; Proteasome Inhibitors; Pyridines; Signal Transduction

Topics: Analysis of Variance; Animals; Anthracenes; Blotting, Western; Cells, Cultured; Early Growth Response Protein 1; Enzyme Inhibitors; Female; Flavonoids; Gonadotropin-Releasing Hormone; Imidazoles; JNK Mitogen-Activated Protein Kinases; Luteinizing Hormone, beta Subunit; Male; MAP Kinase Kinase 1; Neoplasm Proteins; Phosphorylation; Pituitary Gland; Pyridines; Rats; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors

Topics: Androstadienes; Anthracenes; Anticarcinogenic Agents; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Flavonoids; Genistein; HeLa Cells; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Uterine Cervical Neoplasms; Wortmannin

Topics: Animals; Anthracenes; Bacterial Outer Membrane Proteins; Butadienes; Cell Adhesion Molecules; Cell Survival; Cronobacter sakazakii; Dendritic Cells; Enterobacteriaceae Infections; Enzyme Inhibitors; Epithelial Cells; Flavonoids; HeLa Cells; Humans; Imidazoles; Interleukin-10; Lectins, C-Type; Lipopolysaccharides; Lymphocyte Activation; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Mitogen-Activated Protein Kinase Kinases; Nitriles; Pyridines; Rats; Receptors, Cell Surface; Transfection; Transforming Growth Factor beta

Topics: Anthracenes; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibrinolysin; Fibroblasts; Flavonoids; Gingiva; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 1; NF-kappa B; Peptides; Phosphorylation; Plasminogen; RNA, Messenger; Serine Proteinase Inhibitors; Signal Transduction; Triclosan; Tumor Necrosis Factor-alpha; Urokinase-Type Plasminogen Activator

Topics: Amino Acids, Cyclic; Anthracenes; Calcium; Carbachol; Cell Line; Cell Polarity; Chlorides; Cholinergic Agonists; Colon; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Intestinal Mucosa; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Phosphorylation; Potassium; Quinazolines; Thapsigargin; Tyrphostins

Topics: Animals; Anthracenes; Arthritis, Experimental; Cytokines; Enzyme Inhibitors; Female; Flavonoids; Glycation End Products, Advanced; HMGB1 Protein; Imidazoles; Lipopolysaccharides; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Toll-Like Receptor 2; Toll-Like Receptor 4; Up-Regulation

Topics: Anthracenes; Bone Marrow Cells; Cells, Cultured; Child; Child, Preschool; Female; Flavonoids; Humans; Imidazoles; Infant; Leukemia Inhibitory Factor; Male; Myelodysplastic Syndromes; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Serum; Stromal Cells

Topics: Active Transport, Cell Nucleus; Animals; Anthracenes; Cell Line; Cell Nucleus; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; Insulin-Like Growth Factor I; Ligands; MAP Kinase Kinase 4; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptors, Androgen; Signal Transduction

Topics: Anthracenes; Apoptosis; Blotting, Western; Caspase 3; Cells, Cultured; Endothelial Cells; Flavonoids; Flow Cytometry; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Palmitic Acid; Pyridines; Stem Cells; Up-Regulation

Topics: Animals; Anthracenes; Apoptosis; Cell Line; Cell Nucleus; Cell Survival; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Fluorescence Resonance Energy Transfer; Helicobacter Infections; Helicobacter pylori; Host-Pathogen Interactions; Imidazoles; Immunoblotting; Macromolecular Substances; Macrophages; Mice; Mice, Inbred C57BL; Ornithine Decarboxylase; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factor AP-1

Topics: Acetylcysteine; Anthracenes; Apoptosis; Dual Specificity Phosphatase 1; Flavonoids; Gene Knockdown Techniques; Glucosephosphate Dehydrogenase; Hep G2 Cells; Humans; Hydrogen Peroxide; Imidazoles; Mitogen-Activated Protein Kinases; Protein Tyrosine Phosphatases; Pyridines

Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adult; Anthracenes; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chemokine CCL2; Chemokine CXCL10; Chemokine CXCL11; Chromones; Chronic Periodontitis; Enzyme Inhibitors; Female; Fibroblasts; Flavonoids; Gingiva; Humans; Imidazoles; Inflammation Mediators; Interferon-gamma; Interleukin-6; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Male; Middle Aged; Morpholines; Nod2 Signaling Adaptor Protein; Periodontal Attachment Loss; Periodontal Pocket; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Tumor Necrosis Factor-alpha

Topics: Adenosine Triphosphate; Anthracenes; Antimicrobial Cationic Peptides; Calcium-Calmodulin-Dependent Protein Kinases; Cathelicidins; Cell Movement; Cells, Cultured; Dental Pulp; Endodontics; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Heparin; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Phosphorylation; Protein Tyrosine Phosphatases; Purinergic P2 Receptor Agonists; Quinazolines; Receptors, Cell Surface; Receptors, Purinergic P2X; Regenerative Medicine; Tissue Engineering; Tyrphostins

Topics: Animals; Anthracenes; Antibodies; Antigen Presentation; Antigens; Antigens, CD1d; CD3 Complex; Cytokines; Down-Regulation; Enzyme Inhibitors; Flavonoids; Galactosylceramides; Imidazoles; Interferon-gamma; Interleukin-2; Interleukin-4; Mice; Mice, Inbred C57BL; Natural Killer T-Cells; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Receptors, Antigen, T-Cell; Spleen

Topics: Adolescent; Adult; Animals; Anthracenes; Autoantigens; Calcium-Calmodulin-Dependent Protein Kinases; Cell Culture Techniques; Chemokine CCL2; Cytokines; Female; Flavonoids; Humans; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Joint Dislocations; Male; Microarray Analysis; NF-kappa B; Osteoarthritis; Rats; Rats, Inbred Lew; RNA, Messenger; Synovial Fluid; Synovial Membrane; Synovitis; Temporomandibular Joint Disc; Temporomandibular Joint Disorders; Young Adult

Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Anthracenes; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Caspase 3; Caspase 7; Caspase 9; Cell Line, Tumor; Cyclosporins; Cytochromes c; DNA Damage; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutathione; Humans; Imidazoles; Immunoblotting; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Pyridines; Reactive Oxygen Species; U937 Cells

Topics: Animals; Anthracenes; Cardiomyopathy, Dilated; Fibrosis; Flavonoids; Heart Function Tests; Lamin Type A; Male; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Mutation; Myocardium; Pilot Projects; Protein Kinase Inhibitors

Topics: Anthracenes; Cell Movement; Cells, Cultured; Coronary Vessels; Extracellular Signal-Regulated MAP Kinases; Fibrin; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Pyridines

Topics: Actin Cytoskeleton; Animals; Anthracenes; Burns; Chemokine CCL2; Endothelial Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; Intercellular Adhesion Molecule-1; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; P-Selectin; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Tight Junctions

Topics: Animals; Anthracenes; Antioxidants; Ascorbic Acid; Blotting, Western; Caspase 3; Catalase; Cell Line; Cell Survival; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Heme Oxygenase-1; Insulin; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myoblasts, Skeletal; NF-kappa B; Oxidative Stress; Phosphorylation; Protoporphyrins; Reactive Oxygen Species; Signal Transduction

Topics: 14-3-3 Proteins; Anthracenes; Biomarkers, Tumor; Blotting, Western; Cells, Cultured; Coculture Techniques; Culture Media, Conditioned; Dermis; Exonucleases; Exoribonucleases; Fibroblasts; Flavonoids; Gene Expression Profiling; Humans; Imidazoles; Keratinocytes; MAP Kinase Signaling System; Pyridines; Reverse Transcriptase Polymerase Chain Reaction

Topics: Acetylcysteine; Anthracenes; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase Inhibitors; Cell Line, Tumor; Chromatin; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glioma; Humans; JNK Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Vitamin K 3

Topics: Anthracenes; Cell Hypoxia; Cell Line, Tumor; Down-Regulation; Flavonoids; GPI-Linked Proteins; HEK293 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Mitogen-Activated Protein Kinases; Neoplasms; Promoter Regions, Genetic; Protein Binding; Pyridines; Response Elements; RNA, Messenger; Signal Transduction

Topics: Animals; Anthracenes; Antineoplastic Agents; Apoptosis; Benzamides; Flavonoids; Flow Cytometry; Imatinib Mesylate; Imidazoles; Melanoma, Experimental; Membrane Potentials; Mice; Mitochondria; Piperazines; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Reactive Oxygen Species

Topics: Adrenergic alpha-2 Receptor Agonists; Animals; Anthracenes; Aorta; Dexmedetomidine; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Male; Muscle Contraction; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Protein Isoforms; Pyridines; Rats; Rats, Sprague-Dawley

Topics: Amino Acid Chloromethyl Ketones; Anthracenes; Antithrombins; Blotting, Western; Butadienes; Cell Line; Cells, Cultured; Cyclooxygenase 2 Inhibitors; Enzyme Inhibitors; Flavonoids; Gene Expression; Glycoproteins; Hirudins; Humans; JNK Mitogen-Activated Protein Kinases; Lipoproteins, VLDL; Macrophages; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; Nitrobenzenes; Reverse Transcriptase Polymerase Chain Reaction; Sesquiterpenes; Signal Transduction; Sulfonamides; Thrombin; Time Factors

Topics: Anthracenes; Aquaporin 1; Cell Line; Down-Regulation; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Peptidoglycan; Pyridines; Staphylococcus aureus

Topics: Animals; Anthracenes; Cells, Cultured; Coumarins; Enzyme Inhibitors; Flavonoids; GABA Modulators; Humans; Hypnotics and Sedatives; Interleukin-1beta; Interleukin-6; Midazolam; Mitogen-Activated Protein Kinases; Neuroglia; Propofol; Rats; STAT3 Transcription Factor

Topics: Anthracenes; Arthritis, Rheumatoid; Cell Cycle; Cell Proliferation; Cells, Cultured; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Flavonoids; G1 Phase Cell Cycle Checkpoints; Genistein; Humans; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Synovial Membrane; Tumor Necrosis Factor-alpha

Topics: Anthracenes; Cell Line; Chromones; Connective Tissue Growth Factor; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; JNK Mitogen-Activated Protein Kinases; Morpholines; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Stress, Mechanical

Topics: Animals; Anthracenes; Cecum; Cell Line; Cell Survival; Chromones; Cyclooxygenase 2; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Ethanol; Flavonoids; Flowers; Genetic Vectors; Heme Oxygenase-1; HMGB1 Protein; Imidazoles; Lipopolysaccharides; Lung; Macrophages; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Morpholines; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; Plant Extracts; Protein Transport; Prunella; Pyridines; Sepsis; Signal Transduction; Transfection

Topics: Animals; Anthracenes; Apoptosis; Blotting, Western; Cell Line; Flavonoids; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Polyethylene Glycols; Polymethacrylic Acids; Transcription Factors

Topics: 3T3 Cells; Androstadienes; Animals; Anthracenes; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Escherichia coli; Flavonoids; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Osteoblasts; Osteoprotegerin; Phosphoinositide-3 Kinase Inhibitors; Porphyromonas endodontalis; RANK Ligand; Real-Time Polymerase Chain Reaction; Receptor Activator of Nuclear Factor-kappa B; Signal Transduction; Time Factors; Toll-Like Receptor 2; Toll-Like Receptor 4; Wortmannin

Topics: Anthracenes; Endothelial Cells; Flavonoids; Humans; Imidazoles; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NF-kappa B; Nicotine; Protein Kinase Inhibitors; Pyridines; Reactive Oxygen Species; Receptors, Urokinase Plasminogen Activator; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transcription Factor AP-1

Topics: Anthracenes; Cells, Cultured; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Interleukin-8; Lipopolysaccharides; MAP Kinase Signaling System; MicroRNAs; NF-kappa B; Nuclear Receptor Co-Repressor 2; Pyridines; Transcription, Genetic; Transcriptional Activation; U937 Cells

Topics: Acetic Acid; Androstadienes; Animals; Anthracenes; Benzoquinones; Disease Models, Animal; Flavonoids; Imidazoles; Injections, Spinal; Male; MAP Kinase Signaling System; Mice; Microglia; Nociception; Nociceptive Pain; Pain; Pain Measurement; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Spinal Cord; Wortmannin

Topics: Anthracenes; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Flavonoids; Ginsenosides; Hep G2 Cells; Humans; Matrix Metalloproteinase 1; Mitogen-Activated Protein Kinases; Promoter Regions, Genetic; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transcription Factor AP-1

Topics: Animals; Anthracenes; Cell Line, Transformed; Cicatrix; Collagen Type I; Connective Tissue Growth Factor; Cornea; Corneal Stroma; Enzyme Activation; Eye Injuries, Penetrating; Fibroblasts; Fibronectins; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Phosphorylation; Pyridines; Rats; Rats, Wistar; Telomerase; Transforming Growth Factor beta1; Wound Healing

Topics: Anthracenes; Benzamides; Catechin; Cell Line; Cells, Cultured; Connective Tissue Growth Factor; Dinoprostone; Dioxoles; Dose-Response Relationship, Drug; Fibroblasts; Flavonoids; Humans; Imidazoles; Lung; MAP Kinase Kinase 4; Mouth Mucosa; Oral Submucous Fibrosis; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta1

Topics: Anthracenes; Cell Line, Tumor; Chemokines; Cytokines; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Macrophages; Mitogen-Activated Protein Kinase Kinases; Pyridines; Shiga Toxin 1; Stress, Physiological; Time Factors

Topics: Animals; Anthracenes; Calcitonin Gene-Related Peptide; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Migraine Disorders; Neurons; Organ Culture Techniques; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Trigeminal Ganglion; Tumor Necrosis Factor-alpha; Up-Regulation

Topics: Adrenal Gland Neoplasms; Animals; Anthracenes; Apoptosis; Brain-Derived Neurotrophic Factor; Carrier Proteins; Cell Line, Tumor; Cell Survival; Cycloheximide; Extracellular Signal-Regulated MAP Kinases; Flavonoids; HEK293 Cells; Homer Scaffolding Proteins; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Pheochromocytoma; Protein Kinase Inhibitors; Protein Synthesis Inhibitors; Pyridines; Rats; RNA Interference; RNA, Small Interfering; Tumor Necrosis Factor-alpha

Topics: Anthracenes; Blotting, Western; Cells, Cultured; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Interleukin 1 Receptor Antagonist Protein; Interleukin-1beta; Interleukin-23 Subunit p19; JNK Mitogen-Activated Protein Kinases; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Periodontal Ligament; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription Factor AP-1; Transcription Factor RelA; Up-Regulation

Topics: Anthracenes; Anti-Bacterial Agents; Blotting, Northern; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Dermis; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Flavonoids; Gene Expression Regulation; Hepatocyte Growth Factor; Humans; Infant, Newborn; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Phosphorylation; Polymyxin B

Topics: Animals; Anthracenes; Arthritis, Experimental; Carrageenan; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Pyridines; Random Allocation; Rats; Rats, Sprague-Dawley

Topics: Animals; Anthracenes; Cells, Cultured; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation; Inflammation; Interleukin-12 Subunit p40; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Macrophages, Peritoneal; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; NF-kappa B; Peptidoglycan; PPAR gamma; RNA Interference; RNA, Small Interfering; Toll-Like Receptor 2; Transcription Factor RelA; Tumor Necrosis Factor-alpha

Topics: Anthracenes; Epithelial Cells; Escherichia coli Infections; Flavonoids; Gene Expression; Humans; Imidazoles; Interleukin-1; JNK Mitogen-Activated Protein Kinases; Kidney; MAP Kinase Signaling System; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; RNA Stability; RNA, Messenger

Topics: Angiogenesis Inhibitors; Animals; Animals, Genetically Modified; Anthracenes; Cell Line, Tumor; Cell Movement; Chromones; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glioma; High-Throughput Screening Assays; Humans; Imidazoles; Macrophages; MAP Kinase Kinase 4; Morpholines; Neovascularization, Pathologic; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Signal Transduction; Transforming Growth Factor beta1; Xenograft Model Antitumor Assays; Zebrafish

Topics: 3T3-L1 Cells; Adiponectin; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Anthracenes; Chromones; Enzyme Inhibitors; Flavonoids; MAP Kinase Kinase 4; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Ribonucleotides; RNA, Messenger; Thioctic Acid

Topics: Adolescent; Adult; Anthracenes; Cell Culture Techniques; Chemokine CCL20; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Flavonoids; Gene Expression Profiling; Humans; Imidazoles; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Joint Dislocations; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NF-kappa B; Oligonucleotide Array Sequence Analysis; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Synovial Membrane; Temporomandibular Joint Disorders; Time Factors; Tumor Necrosis Factor-alpha; Young Adult

Topics: Anthracenes; Blotting, Western; Caveolin 1; Cell Survival; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gingiva; Humans; Inflammation; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 1; Matrix Metalloproteinase 10; Matrix Metalloproteinase 14; Periodontal Ligament; Periodontitis; Phosphorylation; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Endothelial Growth Factor A

Topics: Anastomosis, Surgical; Animals; Anthracenes; Apoptosis; Caspase 3; Cell Proliferation; Cells, Cultured; Cicatrix; Cytochromes c; Cytoprotection; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Immunosuppressive Agents; JNK Mitogen-Activated Protein Kinases; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Tacrolimus

Topics: Animals; Anthracenes; Cartilage, Articular; Cattle; Cell Dedifferentiation; Cell Proliferation; Cell Survival; Chondrocytes; Chondrogenesis; Extracellular Matrix; Flavonoids; Gene Expression; Glycosaminoglycans; Imidazoles; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phenotype; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines

Topics: Animals; Animals, Newborn; Anthracenes; Blotting, Western; Cells, Cultured; Endothelin-1; Enzyme Inhibitors; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Oligopeptides; Patch-Clamp Techniques; Peptides, Cyclic; Piperidines; Pyridines; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

Topics: Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cell Culture Techniques; Cell Movement; Cells, Cultured; Connective Tissue Growth Factor; Curcumin; Enzyme Inhibitors; Fibroblasts; Flavonoids; Gingiva; Gingival Overgrowth; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lovastatin; MAP Kinase Kinase 4; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Signal Transduction; Smad3 Protein; src-Family Kinases; Transforming Growth Factor beta1

Topics: Adult; Anthracenes; Calcium-Calmodulin-Dependent Protein Kinases; Cell Culture Techniques; Cells, Cultured; Cytokines; Dose-Response Relationship, Drug; Endothelin B Receptor Antagonists; Endothelin Receptor Antagonists; Endothelin-1; Female; Flavonoids; Humans; Imidazoles; Interleukin-1beta; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Peptides, Cyclic; Periodontal Ligament; Periodontitis; Piperidines; Pyridines; Time Factors; Tumor Necrosis Factor-alpha

Topics: Acetylcysteine; Anthracenes; Antioxidants; Breast Neoplasms; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; MCF-7 Cells; Oxidative Stress; Peroxiredoxins; Reactive Oxygen Species; RNA, Messenger; Up-Regulation

Topics: Animals; Anthracenes; Bone Marrow Cells; Cell Movement; Cells, Cultured; Chemokine CCL2; Chemotaxis, Leukocyte; Extracellular Signal-Regulated MAP Kinases; Flavonoids; G-Protein-Coupled Receptor Kinase 2; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Immunological; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptors, CCR2; RNA Interference; RNA, Small Interfering; Toll-Like Receptor 4

Topics: Alkaline Phosphatase; Animals; Anthracenes; Calcium-Calmodulin-Dependent Protein Kinases; Cell Culture Techniques; Cell Differentiation; Cell Line; Cell Proliferation; Coculture Techniques; Core Binding Factor Alpha 1 Subunit; Culture Media, Conditioned; Embryonic Stem Cells; Fibroblast Growth Factor 4; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Fibroblasts; Flavonoids; Gingiva; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Osteocalcin; Osteogenesis; Osteopontin; Periodontal Ligament; Skin

Topics: Anthracenes; Chromones; Down-Regulation; Epithelial-Mesenchymal Transition; Flavonoids; HEK293 Cells; Homeodomain Proteins; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 1; MAP Kinase Signaling System; Membrane Glycoproteins; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; RNA Interference; RNA, Small Interfering; Tight Junctions; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Suppressor Proteins; Zinc Finger E-box-Binding Homeobox 1

Topics: Anthracenes; Catechin; Cells, Cultured; Chemokine CCL11; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Gingiva; Humans; Imidazoles; Interleukin-1beta; Interleukin-4; JNK Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Th2 Cells; Tumor Necrosis Factor-alpha

Topics: Alanine Transaminase; Animals; Anthracenes; Aspartate Aminotransferases; Carbon Monoxide; Ethanol; Flavonoids; Glutathione; Heme Oxygenase-1; Hepatocytes; Imidazoles; Interleukin-6; L-Lactate Dehydrogenase; Liver Diseases, Alcoholic; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Organometallic Compounds; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Phytochemicals; Pyridines; Quercetin; Rats; Tumor Necrosis Factor-alpha

Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MCF-7 Cells; Myeloid Cell Leukemia Sequence 1 Protein; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA Interference; RNA, Small Interfering; Superoxide Dismutase; Triple Negative Breast Neoplasms; Withanolides

Topics: Adenosine Triphosphate; Anthracenes; Antioxidants; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Survival; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Histones; HL-60 Cells; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Leukemia, Promyelocytic, Acute; M Phase Cell Cycle Checkpoints; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Reactive Oxygen Species

Topics: Adipose Tissue; Adult; Anthracenes; Chemokine CXCL12; Culture Media, Conditioned; Epidermal Growth Factor; Female; Flavonoids; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Lipectomy; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Stem Cells; Vascular Endothelial Growth Factor A

Topics: Acute Disease; Animals; Anthracenes; Ceruletide; Cyclic AMP; Flavonoids; Immunoblotting; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neutrophil Infiltration; Pancreas; Pancreatitis; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Rats; Rats, Wistar; Time Factors

Topics: Alkaline Phosphatase; Animals; Anthracenes; Antlers; Blotting, Western; Calcium; Cell Line; Collagen; Deer; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Male; MAP Kinase Signaling System; Osteoblasts; Osteogenesis; Pyridines; Real-Time Polymerase Chain Reaction

Topics: Anthracenes; Apoptosis; Benzothiazoles; Caspase 3; Caspase 9; Cell Line, Tumor; Cyclin-Dependent Kinase Inhibitor p21; Diterpenes, Kaurane; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonoids; G1 Phase Cell Cycle Checkpoints; Humans; Imidazoles; Isodon; JNK Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Phosphorylation; Plant Preparations; Pyridines; RNA, Messenger; Toluene; Tumor Suppressor Protein p53

Topics: Anthracenes; Cell Hypoxia; Cell Line, Tumor; Flavonoids; HMGB1 Protein; Humans; Imidazoles; MAP Kinase Signaling System; NF-kappa B; Protein Kinase Inhibitors; Pyridines; Pyrrolidines; RNA, Messenger; Thiocarbamates

Topics: 3T3-L1 Cells; Adipose Tissue; Androstadienes; Animals; Anthracenes; Butadienes; Chromones; Dactinomycin; Endothelin-1; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Morpholines; Nitriles; Oligopeptides; Piperidines; Proto-Oncogene Proteins c-akt; Resistin; Signal Transduction; STAT3 Transcription Factor; Tyrphostins; Wortmannin

Topics: Anthracenes; Apoptosis; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Flavonoids; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Pyridines; Quercetin; TRPM Cation Channels

Topics: Anthracenes; Antioxidant Response Elements; Benzofurans; Cell Survival; Flavonoids; Heme Oxygenase-1; Hep G2 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-E2-Related Factor 2; Oxidative Stress; Phosphorylation; Protective Agents; Reactive Oxygen Species; Signal Transduction; tert-Butylhydroperoxide; Up-Regulation

Topics: Animals; Anthracenes; Anti-Inflammatory Agents; Benzhydryl Compounds; Cell Line; Endocrine Disruptors; Enzyme Activation; Estradiol; Estrogen Receptor Antagonists; Estrogen Receptor Modulators; Estrogens; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Fulvestrant; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Microglia; Neurodegenerative Diseases; NF-kappa B; Phenols; Tumor Necrosis Factor-alpha

Topics: Animals; Animals, Newborn; Anthracenes; Butadienes; Cell Hypoxia; Flavonoids; Gene Expression Regulation; Heart Ventricles; Hepatocyte Growth Factor; JNK Mitogen-Activated Protein Kinases; Microfilament Proteins; Myocytes, Cardiac; Nitriles; Oxygen; Primary Cell Culture; Protein Kinase Inhibitors; Rats; RNA, Messenger; Signal Transduction

Topics: Anthracenes; Bronchi; Cells, Cultured; Epithelial Cells; Flavonoids; Gene Expression; Humans; Interleukin-8; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Phosphorylation; Protein Kinase Inhibitors; Pseudomonas aeruginosa; Pseudomonas Infections; Pyrrolidines; RNA, Messenger; Thiocarbamates

Topics: Anthracenes; Apoptosis; bcl-X Protein; Caffeic Acids; Cell Line, Tumor; Chromones; Flavonoids; Gene Expression Regulation, Developmental; Hematopoiesis; Humans; Macrophage Colony-Stimulating Factor; Macrophages; MAP Kinase Signaling System; Monocytes; Morpholines; NF-kappa B; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Sesquiterpenes; Signal Transduction; Tetradecanoylphorbol Acetate

Topics: Anthracenes; Cell Line; Cell Survival; Chemokines; Flavonoids; Humans; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Phosphorylation; Protein Kinase Inhibitors; Sirolimus; TOR Serine-Threonine Kinases

Topics: 3T3 Cells; Animals; Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Down-Regulation; Fibroblast Growth Factor 2; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Recombinant Proteins; Resveratrol; Stilbenes

Topics: Adipose Tissue; Alzheimer Disease; Anthracenes; Cell Line, Tumor; Cell Survival; Chromones; Culture Media, Conditioned; Flavonoids; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction

Topics: Acrylates; Angiotensin II; Animals; Anthracenes; Cell Line; Cell Movement; Cell Proliferation; Cytokines; Early Growth Response Protein 1; Flavonoids; Gene Expression Regulation; Imidazoles; Macrophages; Male; MAP Kinase Signaling System; Mice; Prostaglandin D2; Thiophenes; Up-Regulation

Topics: Alkaline Phosphatase; Animals; Anthracenes; Bone Density Conservation Agents; Cell Differentiation; Cell Proliferation; Collagen Type I; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation, Developmental; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; Mesenchymal Stem Cells; Osteoblasts; Osteocalcin; Osteogenesis; Osteopontin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction

Topics: Anthracenes; Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cell Line; Cell Proliferation; Collagen Type I; Collagen Type IV; Dose-Response Relationship, Drug; Extracellular Matrix; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mesangial Cells; Mevalonic Acid; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyridines; Signal Transduction; Transforming Growth Factor beta1

Topics: Active Transport, Cell Nucleus; alpha Karyopherins; Animals; Anthracenes; beta Karyopherins; Cells, Cultured; Flavonoids; Gene Expression; Male; Mitogen-Activated Protein Kinases; Myofibroblasts; Plasminogen Activator Inhibitor 1; Rats, Sprague-Dawley; Smad Proteins; Transforming Growth Factor beta1

Topics: Animals; Anthracenes; Benzophenanthridines; Cells, Cultured; Chromones; Colon; Flavonoids; Genistein; Imidazoles; Interstitial Cells of Cajal; Intestine, Small; Membrane Potentials; Mice; Mitogen-Activated Protein Kinases; Morpholines; Naphthalenes; Protein-Tyrosine Kinases; Pyridines; Rifabutin

Topics: Anthracenes; Benzamides; Catechin; Cells, Cultured; Collagen Type I; Dioxoles; Early Growth Response Protein 1; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Humans; Mouth Mucosa; Oral Submucous Fibrosis; Signal Transduction; Transforming Growth Factor beta1

Topics: Acute Lung Injury; Animals; Anthracenes; Apoptosis; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; Uncoupling Protein 2

Topics: Anthracenes; Fibroblasts; Flavonoids; Humans; Interleukin-6; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Phosphorylation; Plant Extracts; Procollagen; Pterocarpus; Skin; Skin Aging; Transcription Factor AP-1; Transforming Growth Factor beta; Ultraviolet Rays

Topics: Anthracenes; Cell Line, Tumor; Cell Movement; Female; Flavonoids; Gene Knockdown Techniques; Humans; Leptin; MAP Kinase Signaling System; Matrix Metalloproteinase 7; Neoplasm Invasiveness; Ovarian Neoplasms

Topics: Animals; Anthracenes; Becaplermin; Cell Line; Cell Movement; Flavonoids; HSP27 Heat-Shock Proteins; Imidazoles; Mice; Mitogen-Activated Protein Kinases; Osteoblasts; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Pyridines; Sirolimus

Topics: Animals; Anisomycin; Anthracenes; Flagella; Flavonoids; Imidazoles; Leishmania donovani; MAP Kinase Signaling System; Microscopy, Video; Movement; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protozoan Proteins

Topics: Animals; Anthracenes; Cell Movement; Cells, Cultured; Epidermal Growth Factor; Flavonoids; Heterocyclic Compounds, 4 or More Rings; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Resveratrol; rho-Associated Kinases; Sirtuin 1; Stilbenes

Topics: Acetylcholine; Animals; Anthracenes; Aorta; Basic Helix-Loop-Helix Transcription Factors; Blood Pressure; Body Weight; Bone Morphogenetic Protein 4; Carrier Proteins; Chronic Disease; Disease Models, Animal; Endothelium, Vascular; Flavonoids; Hypertension; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; In Vitro Techniques; Kidney; Male; Nitric Oxide Synthase Type III; Nitroprusside; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats, Sprague-Dawley; Surgical Instruments; Systole; Vasodilation

Topics: Alkaline Phosphatase; Animals; Anthracenes; Biomarkers; Cell Differentiation; Cell Line; Dexamethasone; Down-Regulation; Enzyme Inhibitors; Flavonoids; Imidazoles; Integrin-Binding Sialoprotein; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Odontoblasts; Osteogenesis; Osteopontin; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Signal Transduction; Up-Regulation

Topics: Anthracenes; Bone Marrow Cells; Calcium; Cell Differentiation; Dental Cementum; Flavonoids; Gene Expression Regulation; Humans; Mesenchymal Stem Cells; Proteins; Wnt Signaling Pathway; Wnt3A Protein

Topics: Anthracenes; Autocrine Communication; Axitinib; Butadienes; Flavonoids; Gene Expression Regulation; Human Umbilical Vein Endothelial Cells; Humans; Imidazoles; Indazoles; MAP Kinase Kinase 1; MAP Kinase Kinase 4; Membrane Proteins; Nitriles; Phosphatidylinositol 3-Kinases; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; Pyrimidines; RNA, Small Interfering; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

Topics: Annexin A3; Anthracenes; Cell Line, Tumor; Cell Movement; Cell Survival; Colorectal Neoplasms; Down-Regulation; Drug Resistance, Neoplasm; Flavonoids; Gene Expression Regulation, Neoplastic; Gene Silencing; HCT116 Cells; Humans; MAP Kinase Signaling System; Oxaliplatin

Topics: Animals; Anthracenes; Anthraquinones; Cell Proliferation; Cells, Cultured; Dideoxyadenosine; Diterpenes, Kaurane; Flavonoids; Hematopoietic Stem Cells; Janus Kinases; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Neural Stem Cells; NF-kappa B; Nitriles; Phosphorylation; Pyrazoles; Pyrimidines; Regenerative Medicine; Signal Transduction; STAT3 Transcription Factor; Sulfonamides

Topics: Adult; Anilides; Anthracenes; Cell Line; Collagen Type I; Collagen Type I, alpha 1 Chain; Female; Fibroblasts; Flavonoids; Humans; Keloid; Lysophospholipids; Male; MAP Kinase Signaling System; Middle Aged; Mitogen-Activated Protein Kinases; Organophosphonates; Phosphorylation; Pyrazoles; Pyridines; Signal Transduction; Sphingosine; Sphingosine-1-Phosphate Receptors; Young Adult

Topics: Animals; Anthracenes; Apoptosis; Benzo(a)pyrene; Enzyme Inhibitors; Flavonoids; Hemocytes; Imidazoles; Mitogen-Activated Protein Kinases; Pectinidae; Phosphorylation; Pyridines

Topics: Adult; Anthracenes; Cells, Cultured; Chemokines, CXC; Cholesterol Side-Chain Cleavage Enzyme; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Female; Flavonoids; Gene Expression Regulation; Granulosa Cells; Humans; Imidazoles; Phosphoproteins; Polycystic Ovary Syndrome; Progesterone; Progesterone Reductase; Pyridines

Topics: Adolescent; Adult; Anthracenes; Blood Donors; Blood Transfusion; Cell Line; Cell Survival; Erythrocytes; Exosomes; Flavonoids; Humans; Imidazoles; Immunity, Innate; Inflammation Mediators; Male; MAP Kinase Signaling System; Mast Cells; Middle Aged; Mitogen-Activated Protein Kinases; Pyridines; Toll-Like Receptor 3; Young Adult