pd 98059 has been researched along with pd 169316 in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 14 (82.35) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A | 1 |
| Hatakeyama, D; Kawamura, H; Kozawa, O; Matsuno, H; Uematsu, T | 1 |
| Inaguma, Y; Ito, H; Iwamoto, I; Kato, K; Lida, K | 1 |
| Bode, AM; Dong, Z; Liu, G; Ma, WY; Zhang, Y | 1 |
| Hatakeyama, D; Kozawa, O; Uematsu, T | 1 |
| Arena, S; Benatti, U; Corsaro, A; Damonte, G; Florio, T; Millo, E; Schettini, G; Tagliavini, F; Thellung, S; Villa, V | 1 |
| Hatakeyama, D; Ito, H; Kato, K; Kozawa, O; Matsuno, H; Niwa, M; Shibata, T; Tatematsu, N; Uematsu, T | 1 |
| Hara, A; Hatakeyama, D; Hirade, K; Hotta, K; Ito, H; Kanamori, Y; Katayama, M; Kato, K; Kozawa, O; Matsuno, H; Mori, H; Niwa, M; Uematsu, T | 1 |
| Akamatsu, S; Hatakeyama, D; Kozawa, O; Shibata, T; Tanabe, K; Tokuda, H; Yoshida, M | 1 |
| Shafer, LM; Slice, LW | 1 |
| Collman, RG; Freedman, BD; Lee, C; Tomkowicz, B | 1 |
| Harada, A; Kato, K; Kozawa, O; Matsushima-Nishiwaki, R; Takai, S; Tokuda, H; Yasuda, E; Yoshida, M | 1 |
| Carmona-Cuenca, I; Del Castillo, G; Fabregat, I; Fernández, M; Murillo, MM; Ortiz, C; Roncero, C; Sánchez, A | 1 |
| Chen, J; Farhan, M; Liao, R; Little, PJ; Wang, T; Wang, Z; Yan, F; Zheng, W | 1 |
| Dey, CS; Mukhopadhyay, AG; Reddy, GS | 1 |
17 other study(ies) available for pd 98059 and pd 169316
| Article | Year |
|---|---|
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase | 2013 |
Endothelin-1 induces vascular endothelial growth factor synthesis in osteoblasts: involvement of p38 mitogen-activated protein kinase.
Topics: Animals; Endothelial Growth Factors; Endothelin-1; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation; Imidazoles; Lymphokines; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinases; Naphthalenes; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phorbol Esters; Protein Kinase C; Pyridines; Pyrrolidinones; Receptor, Endothelin A; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Protein kinase inhibitors can suppress stress-induced dissociation of Hsp27.
Topics: Anisomycin; Arsenites; Butadienes; Cadmium Chloride; Carcinogens; Dithiothreitol; Enzyme Inhibitors; Flavonoids; Glioma; Heat-Shock Proteins; Humans; Hydrogen Peroxide; Imidazoles; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Nitriles; Osmotic Pressure; Oxidants; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Sodium Compounds; Sorbitol; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 2001 |
Phosphorylation of 4E-BP1 is mediated by the p38/MSK1 pathway in response to UVB irradiation.
Topics: Androstadienes; Carrier Proteins; Eukaryotic Initiation Factor-4E; Flavonoids; Imidazoles; Isoquinolines; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pyridines; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Sirolimus; Sulfonamides; Ultraviolet Rays; Wortmannin | 2002 |
Divergent regulation by p44/p42 MAP kinase and p38 MAP kinase of bone morphogenetic protein-4-stimulated osteocalcin synthesis in osteoblasts.
Topics: Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Butadienes; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Kinetics; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; Osteoblasts; Osteocalcin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines | 2002 |
p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Neuroblastoma; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Prion Diseases; Prions; Pyridines; Tumor Cells, Cultured | 2002 |
Upregulation by retinoic acid of transforming growth factor-beta-stimulated heat shock protein 27 induction in osteoblasts: involvement of mitogen-activated protein kinases.
Topics: Animals; Blotting, Northern; Cell Line; Enzyme Activation; Flavonoids; Heat-Shock Proteins; Imidazoles; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Tretinoin; Up-Regulation | 2002 |
Involvement of p38 mitogen-activated protein kinase in heat shock protein 27 induction in human neutrophils.
Topics: Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Cycloheximide; Dactinomycin; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Heat-Shock Proteins; Humans; Imidazoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neutrophils; Nucleic Acid Synthesis Inhibitors; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Synthesis Inhibitors; Pyridines; Pyrrolidines; RNA, Messenger; Thiocarbamates; Time Factors; Tumor Necrosis Factor-alpha | 2003 |
Involvement of MAP kinases in TGF-beta-stimulated vascular endothelial growth factor synthesis in osteoblasts.
Topics: 3T3 Cells; Angiogenesis Inducing Agents; Animals; Butadienes; Dose-Response Relationship, Drug; Drug Synergism; Endothelial Growth Factors; Flavonoids; Imidazoles; Intercellular Signaling Peptides and Proteins; Lymphokines; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Nitriles; Osteoblasts; Pyridines; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2003 |
Anisomycin induces COX-2 mRNA expression through p38(MAPK) and CREB independent of small GTPases in intestinal epithelial cells.
Topics: Animals; Anisomycin; Bacterial Proteins; Bacterial Toxins; Blotting, Western; Butadienes; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; DNA Primers; Flavonoids; Gene Expression Regulation; Imidazoles; Intestinal Mucosa; Monomeric GTP-Binding Proteins; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; RNA Interference; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Sorbitol | 2005 |
HIV-1 gp120-induced TNF-{alpha} production by primary human macrophages is mediated by phosphatidylinositol-3 (PI-3) kinase and mitogen-activated protein (MAP) kinase pathways.
Topics: Androstadienes; Butadienes; Cells, Cultured; Chromones; Flavonoids; HIV Envelope Protein gp120; Humans; Imidazoles; Macrophages; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Receptors, CCR5; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha; Wortmannin | 2005 |
Prostaglandin D2 induces the phosphorylation of HSP27 in osteoblasts: function of the MAP kinase superfamily.
Topics: Animals; Anthracenes; Cell Line; Enzyme Inhibitors; Flavonoids; Heat-Shock Proteins; Imidazoles; Intracellular Signaling Peptides and Proteins; Mice; Mitogen-Activated Protein Kinases; Osteoblasts; Phosphorylation; Prostaglandin D2; Protein Kinases; Protein Serine-Threonine Kinases | 2006 |
Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism.
Topics: Acetophenones; Animals; Anthracenes; Benzamides; Chromones; Dioxoles; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Heparin-binding EGF-like Growth Factor; Hepatocytes; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Morpholines; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Onium Compounds; Peptides; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quinazolines; rac1 GTP-Binding Protein; Rats; Reactive Oxygen Species; Transforming Growth Factor beta; Tyrphostins; Up-Regulation | 2007 |
Elucidating the role of the FoxO3a transcription factor in the IGF-1-induced migration and invasion of uveal melanoma cancer cells.
Topics: Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Chromones; Flavonoids; Forkhead Box Protein O3; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Imidazoles; Insulin-Like Growth Factor I; Melanoma; Mitogen-Activated Protein Kinase Kinases; Morpholines; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Protein Transport; Proto-Oncogene Proteins c-akt; Signal Transduction; Transcriptional Activation; Uveal Neoplasms | 2016 |
The p38 MAP kinase inhibitor, PD 169316, inhibits flagellar motility in Leishmania donovani.
Topics: Animals; Anisomycin; Anthracenes; Flagella; Flavonoids; Imidazoles; Leishmania donovani; MAP Kinase Signaling System; Microscopy, Video; Movement; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protozoan Proteins | 2017 |