Compounds > pd 98059

pd 98059 and melatonin

pd 98059 has been researched along with melatonin in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's6 (50.00)29.6817
2010's5 (41.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Barrett, P; Morgan, PJ; Ross, AW; Thompson, M; Webster, CA1
Heath, J; Straume, M; Yadav, G; Zatz, M1
Cahill, GM; Hasegawa, M1
Cheng, XW; Gui, SY; Jiang, ZK; Wang, Y; Wei, W; Xiao, LL; Zhou, Q; Zhu, HQ1
Arcangeletti, M; Betti, M; Canonico, B; Ferri, P; Galli, F; Luchetti, F; Papa, S1
Baik, HH; Cho, HY; Chung, JH; Ha, E; Nah, SS; Park, HJ; Won, HJ1
Jeong, SJ; Kang, JW; Kim, JS; Kim, M; Kim, SH; Lee, EM; Park, KH; Park, YG; Rhee, YH1
Liu, L; Reiter, RJ; Xu, Y; Zhu, Y1
Blandino, G; Marani, M; Muti, P; Santoro, R; Strano, S1
Gim, SA; Koh, PO1
Chen, D; Jiang, L; Li, Z; Liu, L; Liu, Y; Pan, Y; Pu, X; Reiter, RJ; Xu, Y1

Other Studies

12 other study(ies) available for pd 98059 and melatonin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
A novel interaction between inhibitory melatonin receptors and protein kinase C-dependent signal transduction in ovine pars tuberalis cells.
    Endocrinology, 1998, Volume: 139, Issue:4

    Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cytosol; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression; Genes, fos; L Cells; Melatonin; Mice; Pituitary Gland; Protein Kinase C; Receptors, Cell Surface; Receptors, Cytoplasmic and Nuclear; Receptors, Melatonin; RNA, Messenger; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate

1998
Are changes in MAPK/ERK necessary or sufficient for entrainment in chick pineal cells?
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Nov-05, Volume: 23, Issue:31

    Topics: Acetylserotonin O-Methyltransferase; Animals; Blood Proteins; Caffeine; Cells, Cultured; Central Nervous System Stimulants; Chickens; Circadian Rhythm; Darkness; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Imidazoles; Light; Melatonin; Mitogen-Activated Protein Kinases; Osmolar Concentration; Pineal Gland; Pyridines

2003
Regulation of the circadian oscillator in Xenopus retinal photoreceptors by protein kinases sensitive to the stress-activated protein kinase inhibitor, SB 203580.
    The Journal of biological chemistry, 2004, May-21, Volume: 279, Issue:21

    Topics: Animals; Casein Kinases; Circadian Rhythm; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Light; Male; MAP Kinase Kinase 4; Melatonin; Mitogen-Activated Protein Kinase Kinases; Oscillometry; Phosphorylation; Photoreceptor Cells; Precipitin Tests; Protein Isoforms; Protein Kinases; Pyridines; Time Factors; Transcription Factors; Xenopus

2004
Melatonin prevents oxidized low-density lipoprotein-induced increase of myosin light chain kinase activation and expression in HUVEC through ERK/MAPK signal transduction.
    Journal of pineal research, 2008, Volume: 45, Issue:3

    Topics: Analysis of Variance; Antioxidants; Blotting, Western; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Immunohistochemistry; Lipoproteins, LDL; MAP Kinase Signaling System; Melatonin; Mitogen-Activated Protein Kinases; Myosin-Light-Chain Kinase; Reverse Transcriptase Polymerase Chain Reaction; Umbilical Veins

2008
ERK MAPK activation mediates the antiapoptotic signaling of melatonin in UVB-stressed U937 cells.
    Free radical biology & medicine, 2009, Feb-01, Volume: 46, Issue:3

    Topics: Apoptosis; Cytochromes c; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; Melatonin; Mitochondria; Monocytes; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Pyridines; Radiation Tolerance; Signal Transduction; U937 Cells; Ultraviolet Rays

2009
Melatonin inhibits human fibroblast-like synoviocyte proliferation via extracellular signal-regulated protein kinase/P21(CIP1)/P27(KIP1) pathways.
    Journal of pineal research, 2009, Volume: 47, Issue:1

    Topics: Aged; Arthritis, Rheumatoid; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Humans; Melatonin; Middle Aged; Signal Transduction; Synovial Membrane

2009
Melatonin promotes osteoblastic differentiation through the BMP/ERK/Wnt signaling pathways.
    Journal of pineal research, 2011, Volume: 51, Issue:2

    Topics: Active Transport, Cell Nucleus; Animals; Antioxidants; beta Catenin; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 4; Calcification, Physiologic; Carrier Proteins; Cell Differentiation; Cell Line; Cell Nucleus; Core Binding Factor Alpha 1 Subunit; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Melatonin; Mice; Osteoblasts; Osteocalcin; Time Factors; Wnt Proteins; Wnt-5a Protein; Wound Healing

2011
Prevention of ERK activation involves melatonin-induced G(1) and G(2) /M phase arrest in the human osteoblastic cell line hFOB 1.19.
    Journal of pineal research, 2012, Volume: 53, Issue:1

    Topics: Antioxidants; Cell Cycle Checkpoints; Cell Line; Cyclin B1; Cyclin D1; Cyclin-Dependent Kinase 4; Down-Regulation; Enzyme Activation; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Melatonin; Osteoblasts; p38 Mitogen-Activated Protein Kinases

2012
Melatonin triggers p53Ser phosphorylation and prevents DNA damage accumulation.
    Oncogene, 2012, Jun-14, Volume: 31, Issue:24

    Topics: Animals; Antioxidants; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; Cell Proliferation; DNA Damage; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Melatonin; Mice; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Promyelocytic Leukemia Protein; Protein Serine-Threonine Kinases; Pyridines; Serine; Transcription Factors; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2012
Melatonin attenuates hepatic ischemia through mitogen-activated protein kinase signaling.
    The Journal of surgical research, 2015, Volume: 198, Issue:1

    Topics: Animals; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Ischemia; Liver; Male; MAP Kinase Signaling System; Melatonin; Mice; Mice, Inbred ICR; Phosphorylation

2015
Inhibition of ERK1/2 Signaling Pathway is Involved in Melatonin's Antiproliferative Effect on Human MG-63 Osteosarcoma Cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 39, Issue:6

    Topics: Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cyclin B1; Cyclin D1; Cyclin-Dependent Kinases; Down-Regulation; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Melatonin; Osteosarcoma; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-akt

2016