pd 98059 and lovastatin

pd 98059 has been researched along with lovastatin in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (20.00)18.2507
2000's7 (70.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Garlock, GL; Jivraj, S; Stapleton, SR; Wagle, A1
Mahata, M; Mahata, SK; O'Connor, DT; Parmer, RJ; Wu, H1
Aklilu, F; Gladu, J; Goltzman, D; Rabbani, SA1
Bank, I; Chess, L; Goldstein, I; Koltakov, A; Li, J; Nir-Glickman, E; Roitelman, J1
Allen, WE; Campbell, M; Sawyer, C; Trimble, ER; Vanhaesebroeck, B1
Khosravi, F; Minden, MD; Penn, LZ; Wong, WW; Wu, J1
Goez, P; Hagelgans, A; Hempel, U; Heyne, B; Jaross, W; Menschikowski, M; Neumeister, V; Siegert, G1
Bifulco, M; Carella, C; Fiorentino, L; Gazzerro, P; Gerbasio, D; Laezza, C; Matarese, G; Mazziotti, G; Portella, G1
Chang, HH; Chang, JZ; Deng, YT; Kuo, MY; Liu, CM; Yang, WH1

Other Studies

10 other study(ies) available for pd 98059 and lovastatin

ArticleYear
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Insulin regulation of glucose-6-phosphate dehydrogenase gene expression is rapamycin-sensitive and requires phosphatidylinositol 3-kinase.
    The Journal of biological chemistry, 1998, Jun-12, Volume: 273, Issue:24

    Topics: Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Flavonoids; Gene Expression Regulation, Enzymologic; Glucosephosphate Dehydrogenase; Insulin; Liver; Lovastatin; Male; Morpholines; Oligopeptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polyenes; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; RNA, Messenger; Sirolimus; Wortmannin

1998
Neurotrophin activation of catecholamine storage vesicle protein gene expression: signaling to chromogranin a biosynthesis.
    Neuroscience, 1999, Volume: 88, Issue:2

    Topics: Alkaloids; Animals; Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Catecholamines; Chamomile; Chromaffin Cells; Chromaffin Granules; Chromogranin A; Chromogranins; Enzyme Inhibitors; Flavonoids; Gene Deletion; Gene Expression; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Mice; Mitogen-Activated Protein Kinase Kinases; Molecular Sequence Data; Mutagenesis; Nerve Growth Factors; Oils, Volatile; PC12 Cells; Peptidylprolyl Isomerase; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Plants, Medicinal; Promoter Regions, Genetic; Protein Kinase Inhibitors; Protein Kinases; Proto-Oncogene Proteins; Rats; Receptor Protein-Tyrosine Kinases; Receptor, trkA; Receptors, Nerve Growth Factor; RNA, Messenger; Transcription, Genetic; Transfection; Type C Phospholipases

1999
Role of mitogen-activated protein kinases in the induction of parathyroid hormone-related peptide.
    Cancer research, 2000, Mar-15, Volume: 60, Issue:6

    Topics: Animals; Antineoplastic Agents; Calcium; Cycloheximide; Dose-Response Relationship, Drug; Flavonoids; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; Lovastatin; Male; Methionine; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutation; Neoplasms, Experimental; Parathyroid Hormone-Related Protein; Proteins; Proto-Oncogene Proteins c-raf; rac1 GTP-Binding Protein; ras Proteins; Rats; Rats, Inbred F344; RNA, Messenger; Signal Transduction; Ultraviolet Rays

2000
Lovastatin and phospholipase Cgamma regulate constitutive and protein kinase C dependent integrin mediated interactions of human T-cells with collagen.
    Cellular immunology, 2003, Volume: 223, Issue:1

    Topics: Cell Adhesion; Collagen Type IV; Flavonoids; Flow Cytometry; Herpesvirus 2, Saimiriine; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Integrin alpha1beta1; Interferon-gamma; Lovastatin; MAP Kinase Kinase 1; Mevalonic Acid; Mitogen-Activated Protein Kinase Kinases; Phospholipase C gamma; Pravastatin; Protein Kinase C; Protein Serine-Threonine Kinases; T-Lymphocytes; Tetradecanoylphorbol Acetate; Type C Phospholipases

2003
Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways.
    Circulation research, 2004, Aug-20, Volume: 95, Issue:4

    Topics: Alkyl and Aryl Transferases; Androstadienes; Anthracenes; Antibodies, Monoclonal; Cells, Cultured; Chemotaxis; Chromones; Class I Phosphatidylinositol 3-Kinases; Farnesyltranstransferase; Flavonoids; Glucose; Humans; Imidazoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Lovastatin; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polyisoprenyl Phosphates; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; ras Proteins; Sesquiterpenes; Sirolimus; TOR Serine-Threonine Kinases; Wortmannin

2004
Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosis.
    Cancer research, 2004, Sep-15, Volume: 64, Issue:18

    Topics: Antineoplastic Agents; Apoptosis; Down-Regulation; Flavonoids; Humans; Leukemia, Myeloid, Acute; Lovastatin; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Polyisoprenyl Phosphates; Proto-Oncogene Proteins c-raf

2004
Statins potentiate the IFN-gamma-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells.
    Biochimica et biophysica acta, 2005, Apr-15, Volume: 1733, Issue:2-3

    Topics: Amides; Aorta; Atorvastatin; Bacterial Proteins; Bacterial Toxins; Butadienes; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cell Line, Tumor; Drug Synergism; Flavonoids; Group II Phospholipases A2; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon-gamma; Janus Kinase 2; Lovastatin; Myocytes, Smooth Muscle; NF-kappa B; Nitriles; Phospholipases A; Phospholipases A2; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyridines; Pyrroles; RNA Stability; Up-Regulation

2005
HMG-CoA reductase inhibitors inhibit rat propylthiouracil-induced goiter by modulating the ras-MAPK pathway.
    Journal of molecular medicine (Berlin, Germany), 2006, Volume: 84, Issue:11

    Topics: Animals; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Transfer Techniques; Goiter; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperplasia; Hypertrophy; Lovastatin; Male; MAP Kinase Signaling System; Phosphorylation; Proliferating Cell Nuclear Antigen; Propylthiouracil; Protein Kinase Inhibitors; Protein Prenylation; ras Proteins; Rats; Rats, Wistar; Terpenes; Thyroid Gland; Thyrotropin

2006
Curcumin inhibits TGFβ1-induced CCN2 via Src, JNK, and Smad3 in gingiva.
    Journal of dental research, 2013, Volume: 92, Issue:7

    Topics: Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cell Culture Techniques; Cell Movement; Cells, Cultured; Connective Tissue Growth Factor; Curcumin; Enzyme Inhibitors; Fibroblasts; Flavonoids; Gingiva; Gingival Overgrowth; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lovastatin; MAP Kinase Kinase 4; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Signal Transduction; Smad3 Protein; src-Family Kinases; Transforming Growth Factor beta1

2013