pd 98059 has been researched along with losartan in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 10 (55.56) | 29.6817 |
| 2010's | 6 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alterman, M; Beaudry, H; Botoros, M; Fändriks, L; Gallo-Payet, N; Hallberg, A; Holm, M; Johansson, B; Karlén, A; Mahalingam, AK; Nyberg, F; Pettersson, A; Plouffe, B; Wallinder, C; Wan, Y; Wu, X | 1 |
| Lu, D; Raizada, MK; Vinson, GP; Yang, H | 1 |
| Akishita, M; Daviet, L; Dzau, VJ; Horiuchi, M; Ito, M; Lehtonen, JY | 1 |
| Bobrovskaya, L; Dunkley, PR; Leal, RB; Odell, A | 1 |
| Chen, H; Li, D; Mehta, JL | 1 |
| Fan, YP; Puri, RN; Rattan, S | 1 |
| de Champlain, J; El Midaoui, A; Laplante, MA; Wu, R | 1 |
| Capuano, V; Coulombe, A; Deroubaix, E; Ferron, L; Renaud, JF; Ruchon, Y | 1 |
| Hama, K; Hanatsuka, K; Kita, H; Mashima, H; Ohashi, A; Ohnishi, H; Satoh, Y; Sugano, K; Tamada, K; Ueda, N; Yasuda, H | 1 |
| Ingelfinger, JR; Moini, B; Zhang, SL | 1 |
| Chen, K; Joseph, J; Joseph, L; Li, D; Mehta, JL | 1 |
| Ferrario, CM; Gallagher, PE; Tallant, EA | 1 |
| Cheng, PW; Cheng, WH; Ho, WY; Hsiao, M; Lu, PJ; Tseng, CJ; Tung, CS | 1 |
| Han, C; Li, M; Liu, J; Mao, J; Pang, X; Wang, B | 1 |
| Clark, MA; Nguyen, C; Tran, H | 1 |
| Kamata, K; Kobayashi, T; Matsumoto, T; Taguchi, K | 1 |
| Chiu, CZ; Shyu, KG; Wang, BW | 1 |
| Cai, W; Cai, X; Gao, F; Huang, D; Lan, J; Shi, G; Xu, H; Zhang, Y; Zheng, F; Zhong, S | 1 |
18 other study(ies) available for pd 98059 and losartan
| Article | Year |
|---|---|
Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Bicarbonates; Biological Availability; Cell Line; Drug Design; Enzyme Activation; Female; Half-Life; In Vitro Techniques; Intestinal Mucosa; Liver; Male; Mitogen-Activated Protein Kinases; Molecular Mimicry; Neurites; Peptides; Radioligand Assay; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Sulfonamides; Swine; Thiophenes; Uterus | 2004 |
Involvement of MAP kinase in angiotensin II-induced phosphorylation and intracellular targeting of neuronal AT1 receptors.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Animals; Biological Transport; Biphenyl Compounds; Brain Stem; Calcium-Calmodulin-Dependent Protein Kinases; Cell Nucleus; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Hypothalamus; Imidazoles; Losartan; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Phosphorylation; Plant Proteins; Protein Processing, Post-Translational; Rats; Rats, Inbred WKY; Signal Transduction; Tetrazoles | 1997 |
Expression of the AT2 receptor developmentally programs extracellular signal-regulated kinase activity and influences fetal vascular growth.
Topics: Angiotensin II; Animals; Blood Vessels; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Culture Media; DNA; Female; Flavonoids; Gene Expression Regulation, Developmental; Imidazoles; Losartan; Mice; Mice, Knockout; Muscle Development; Muscle, Smooth, Vascular; Okadaic Acid; Phosphoproteins; Phosphorylation; Protein Binding; Pyridines; Receptors, Angiotensin; Vanadates | 1999 |
Tyrosine hydroxylase phosphorylation in bovine adrenal chromaffin cells: the role of MAPKs after angiotensin II stimulation.
Topics: Adrenal Glands; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anisomycin; Antihypertensive Agents; Butadienes; Cattle; Chromaffin Cells; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Flavonoids; Imidazoles; Immunoblotting; Losartan; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Phosphoserine; Protein Synthesis Inhibitors; Pyridines; Receptors, Angiotensin; Time Factors; Tyrosine 3-Monooxygenase | 2001 |
Angiotensin II via activation of type 1 receptor upregulates expression of endoglin in human coronary artery endothelial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antigens, CD; Cells, Cultured; Coronary Vessels; Endoglin; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Humans; Losartan; Mitogen-Activated Protein Kinases; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Receptors, Cell Surface; Receptors, Transforming Growth Factor beta; RNA, Messenger; Transcriptional Activation; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2001 |
Comparison of angiotensin II (Ang II) effects in the internal anal sphincter (IAS) and lower esophageal sphincter smooth muscles.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anal Canal; Angiotensin II; Animals; Dose-Response Relationship, Drug; Drug Combinations; Esophagus; Female; Flavonoids; Genistein; Imidazoles; Losartan; Male; Muscle Contraction; Muscle, Smooth; Nicardipine; Opossums; Pyridines; Rabbits; Species Specificity; Tyrphostins | 2002 |
NAD(P)H oxidase activation by angiotensin II is dependent on p42/44 ERK-MAPK pathway activation in rat's vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta; Blood Pressure; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Hypertension; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Cardiovascular; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; Rats; Rats, Sprague-Dawley; Superoxides; Thioctic Acid; Vasoconstrictor Agents | 2003 |
Angiotensin II signaling pathways mediate expression of cardiac T-type calcium channels.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Bosentan; Butadienes; Calcium Channels, T-Type; Calcium-Calmodulin-Dependent Protein Kinases; Cardiomegaly; Constriction, Pathologic; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Flavonoids; Gene Expression; Losartan; Male; Membrane Potentials; Mitogen-Activated Protein Kinase Kinases; Myocytes, Cardiac; Nickel; Nitriles; Oligopeptides; Peptides, Cyclic; Piperidines; Rats; Rats, Wistar; Receptors, Angiotensin; Receptors, Endothelin; RNA, Messenger; Signal Transduction; Sulfonamides | 2003 |
Angiotensin II stimulates DNA synthesis of rat pancreatic stellate cells by activating ERK through EGF receptor transactivation.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blotting, Western; DNA; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Flavonoids; Humans; Losartan; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Pancreas; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Recombinant Proteins; Thymidine; Transcriptional Activation; Tritium | 2004 |
Angiotensin II increases Pax-2 expression in fetal kidney cells via the AT2 receptor.
Topics: Angiotensin II; Animals; Anthracenes; Blotting, Western; Cells, Cultured; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblasts; Flavonoids; Genistein; Imidazoles; Kidney; Losartan; Mice; Microscopy, Fluorescence; Onium Compounds; PAX2 Transcription Factor; Phosphorylation; Plasmids; Pyridines; Receptors, Angiotensin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Time Factors; Transcription Factors; Tyrphostins; Up-Regulation | 2004 |
Transforming growth factor beta receptor endoglin is expressed in cardiac fibroblasts and modulates profibrogenic actions of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Antibodies, Monoclonal; Benzimidazoles; Biphenyl Compounds; Cells, Cultured; Collagen Type I; Endoglin; Fibroblasts; Flavonoids; Gene Expression Regulation; Imidazoles; Intracellular Signaling Peptides and Proteins; Losartan; MAP Kinase Signaling System; Matrix Metalloproteinase 1; Myocardium; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Transforming Growth Factor beta; RNA, Messenger; Signal Transduction; Tetrazoles; Valine; Valsartan | 2004 |
Regulation of ACE2 in cardiac myocytes and fibroblasts.
Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Animals; Animals, Newborn; Atrial Natriuretic Factor; Butadienes; Cells, Cultured; Endothelin-1; Fibroblasts; Flavonoids; Gene Expression Regulation, Enzymologic; Heart Ventricles; Losartan; Mitogen-Activated Protein Kinase 1; Myocytes, Cardiac; Nitriles; Peptide Fragments; Peptidyl-Dipeptidase A; Protein Kinase Inhibitors; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction | 2008 |
Angiotensin II inhibits neuronal nitric oxide synthase activation through the ERK1/2-RSK signaling pathway to modulate central control of blood pressure.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Cyclic N-Oxides; Disease Models, Animal; Enzyme Activation; Flavonoids; Hypertension; Losartan; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Ribosomal Protein S6 Kinases; Signal Transduction; Solitary Nucleus; Spin Labels; Time Factors | 2010 |
Angiotensin II induces the expression of c-reactive protein via MAPK-dependent signal pathway in U937 macrophages.
Topics: Acetylcysteine; Angiotensin II; Antihypertensive Agents; C-Reactive Protein; Flavonoids; Humans; Imidazoles; Losartan; Macrophages; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proline; Pyridines; Thiocarbamates; U937 Cells | 2011 |
Angiotensin III stimulates ERK1/2 mitogen-activated protein kinases and astrocyte growth in cultured rat astrocytes.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin III; Animals; Astrocytes; Brain Stem; Cells, Cultured; Cerebellum; Enzyme Inhibitors; Flavonoids; Imidazoles; Losartan; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley | 2011 |
Angiotensin II type 2 receptor-dependent increase in nitric oxide synthase activity in the endothelium of db/db mice is mediated via a MEK pathway.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Activation; Flavonoids; Losartan; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Kinase Kinases; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type III; Oligopeptides; Phosphorylation; Protein Kinase Inhibitors; Receptor, Angiotensin, Type 2; Signal Transduction; Time Factors; Vasodilation; Vasodilator Agents | 2012 |
Effects of cyclic stretch on the molecular regulation of myocardin in rat aortic vascular smooth muscle cells.
Topics: Angiotensin II; Animals; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation; Humans; Losartan; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nuclear Proteins; Promoter Regions, Genetic; Rats; Signal Transduction; Stress, Mechanical; Trans-Activators | 2013 |
Angiotensin II confers resistance to apoptosis in cardiac myofibroblasts through the AT1/ERK1/2/RSK1 pathway.
Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Apoptosis; Butadienes; Cell Survival; Cycloheximide; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Losartan; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardium; Myofibroblasts; Nitriles; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Signal Transduction; Tumor Necrosis Factor-alpha | 2019 |