pd 98059 has been researched along with leupeptins in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 9 (60.00) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harb, S; Heesemann, J; Hornef, M; Köhler, S; Roggenkamp, A; Rouot, B; Ruckdeschel, K; Zumbihl, R | 1 |
| Fernandes, DJ; Guida, E; Harris, T; Koutsoubos, V; Ravenhall, CE; Schachte, LC; Stewart, AG; Vadiveloo, P; Wilson, JW | 1 |
| Churg, A; Dai, J | 1 |
| Fong, WF; Lam, W; Leung, CH; Wong, NS; Yang, MS; Zhuang, WJ | 1 |
| Alexander, JS; Grisham, MB; Jordan, P; Laroux, FS; Oshima, T; Pavlick, KP; Verma, SK; Williams, L | 1 |
| Fukuda, I; Hatakeyama, M; Imaizumi, T; Matsumiya, T; Munakata, H; Satoh, K; Shibata, T; Tamo, W; Yoshida, H | 1 |
| Brecher, P; Cohen, RA; Hou, X; Jiang, B; Pimentel, DR; Xu, S | 1 |
| Bonjardim, CA; Brasil, BS; De Sousa, LP; Ferreira, PC; Freitas, MH; Kroon, EG; Nogueira, SV; Silva, BM | 1 |
| Liang, S; Sun, R; Tian, Z; Wei, H; Zhang, J | 1 |
| Chiasson, S; Girard, D; Pelletier, M; Ratthé, C | 1 |
| Du, ZX; Gao, YY; Guan, Y; Liu, BQ; Meng, X; Wang, HQ; Zhang, HY | 1 |
| Choo, SJ; Kim, DS; Kwon, SB; Lee, HK; Lee, JH; Na, JI; Park, KC; Park, SH; Song, GY; Yoo, ID | 1 |
| Han, YH; Park, WH | 1 |
| Ebert, B; El-Hawari, Y; Kisiela, M; Malátková, P; Maser, E | 1 |
| Curcio, F; Ferro, F; Spelat, R | 1 |
15 other study(ies) available for pd 98059 and leupeptins
| Article | Year |
|---|---|
Yersinia enterocolitica impairs activation of transcription factor NF-kappaB: involvement in the induction of programmed cell death and in the suppression of the macrophage tumor necrosis factor alpha production.
Topics: Animals; Apoptosis; Cell Line; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Leupeptins; Lipopolysaccharides; Macrophages, Peritoneal; Mice; NF-kappa B; Pyridines; Serotyping; Suppression, Genetic; Transcriptional Activation; Tumor Necrosis Factor-alpha; Yersinia enterocolitica | 1998 |
Beta2-adrenergic receptor agonists and cAMP arrest human cultured airway smooth muscle cells in the G(1) phase of the cell cycle: role of proteasome degradation of cyclin D1.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Albuterol; Calpain; Cells, Cultured; Cyclin D1; Cysteine Endopeptidases; Dinoprostone; DNA; Flavonoids; G1 Phase; Gene Expression Regulation; Humans; Leupeptins; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Muscle, Smooth; Phosphorylation; Proteasome Endopeptidase Complex; Protein Serine-Threonine Kinases; Retinoblastoma Protein; RNA, Messenger; S Phase; Thrombin; Time Factors | 1999 |
Relationship of fiber surface iron and active oxygen species to expression of procollagen, PDGF-A, and TGF-beta(1) in tracheal explants exposed to amosite asbestos.
Topics: Animals; Asbestos, Amosite; Cells, Cultured; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Flavonoids; Gene Expression; Iron; Leupeptins; Male; MAP Kinase Signaling System; NF-kappa B; Platelet-Derived Growth Factor; Procollagen; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; RNA, Messenger; Trachea; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha | 2001 |
PKCdelta-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF.
Topics: Acetophenones; Benzopyrans; Cell Division; Cycloheximide; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flavonoids; GADD45 Proteins; Humans; Imidazoles; Intracellular Signaling Peptides and Proteins; Isoenzymes; Kinetics; Leupeptins; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Proteins; Pyridines; Recombinant Proteins; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Ubiquitins | 2001 |
Regulation and distribution of MAdCAM-1 in endothelial cells in vitro.
Topics: Alkaloids; Animals; Benzophenanthridines; Benzopyrans; Carbazoles; Cell Adhesion Molecules; Cell Line, Transformed; Cysteine Proteinase Inhibitors; Endothelium; Enzyme Inhibitors; Flavonoids; Fluorescent Antibody Technique; Gene Expression; Genistein; Imidazoles; Immunoglobulins; In Vitro Techniques; Indoles; Inflammatory Bowel Diseases; Intestinal Mucosa; Isoquinolines; Leupeptins; MAP Kinase Signaling System; Mice; Mucoproteins; NF-kappa B; Phenanthridines; Pyridines; RNA, Messenger; Tumor Necrosis Factor-alpha | 2001 |
Effect of MG132, a proteasome inhibitor, on the expression of growth related oncogene protein-alpha in human umbilical vein endothelial cells.
Topics: Acetylcysteine; Anthracenes; Cells, Cultured; Chemokine CXCL1; Chemokines, CXC; Cysteine Proteinase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Humans; I-kappa B Proteins; Imidazoles; Intercellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Leupeptins; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Umbilical Veins | 2003 |
Temporal control of NF-kappaB activation by ERK differentially regulates interleukin-1beta-induced gene expression.
Topics: Animals; Blotting, Western; Butadienes; Cells, Cultured; Cyclooxygenase 2; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Genes, Dominant; I-kappa B Proteins; Interleukin-1; Isoenzymes; Leupeptins; Mitogen-Activated Protein Kinases; Multienzyme Complexes; Mutation; Myocytes, Smooth Muscle; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitriles; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Proteasome Endopeptidase Complex; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Time Factors; Vascular Cell Adhesion Molecule-1 | 2004 |
Plasminogen/plasmin regulates c-fos and egr-1 expression via the MEK/ERK pathway.
Topics: Animals; Binding Sites; Blotting, Northern; Blotting, Western; Cell Line; Cholera Toxin; DNA; DNA-Binding Proteins; Dose-Response Relationship, Drug; Early Growth Response Protein 1; Enzyme Activation; Fibrinolysin; Flavonoids; Genes, Dominant; Humans; Immediate-Early Proteins; Leupeptins; Lysine; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Plasminogen; Protein Binding; Proto-Oncogene Proteins c-fos; RNA; RNA, Messenger; Serine Endopeptidases; Signal Transduction; Time Factors; Transcription Factors | 2005 |
Differential roles of constitutively activated ERK1/2 and NF-kappa B in cytotoxicity and proliferation by human NK cell lines.
Topics: Cell Line; Cell Proliferation; Cytotoxicity, Immunologic; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; Flavonoids; Humans; Interferon-gamma; Killer Cells, Natural; Leupeptins; MAP Kinase Signaling System; Membrane Glycoproteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; RNA, Messenger; Signal Transduction | 2005 |
Molecular mechanisms involved in interleukin-4-induced human neutrophils: expression and regulation of suppressor of cytokine signaling.
Topics: Apoptosis; Cycloheximide; Dose-Response Relationship, Drug; Flavonoids; Gene Expression Profiling; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Imidazoles; Interleukin-4; Leupeptins; Neutrophils; Pyridines; Receptors, Interleukin-4, Type I; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship; Suppressor of Cytokine Signaling Proteins; Tyrphostins | 2007 |
Inhibition of the JNK signalling pathway enhances proteasome inhibitor-induced apoptosis of kidney cancer cells by suppression of BAG3 expression.
Topics: Adaptor Proteins, Signal Transducing; Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Kidney Neoplasms; Leupeptins; Mitogen-Activated Protein Kinase 8; p38 Mitogen-Activated Protein Kinases; Proteasome Inhibitors; Pyridines; Signal Transduction | 2009 |
Hypopigmentary action of dihydropyranocoumarin D2, a decursin derivative, as a MITF-degrading agent.
Topics: Animals; Benzopyrans; Butyrates; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Hypopigmentation; Leupeptins; Lysosomes; Melanins; Melanocytes; Mice; Microphthalmia-Associated Transcription Factor; Molecular Structure; Monophenol Monooxygenase; Proteasome Inhibitors; Pyranocoumarins | 2010 |
Treatment with p38 inhibitor partially prevents Calu-6 lung cancer cell death by a proteasome inhibitor, MG132.
Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Cycle; Cell Proliferation; Cysteine Proteinase Inhibitors; Flavonoids; Glutathione; Humans; Imidazoles; Leupeptins; Lung Neoplasms; Membrane Potential, Mitochondrial; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; Tumor Cells, Cultured | 2010 |
Regulation of human carbonyl reductase 3 (CBR3; SDR21C2) expression by Nrf2 in cultured cancer cells.
Topics: Alcohol Oxidoreductases; Animals; Cell Line; Cell Line, Tumor; Colonic Neoplasms; Cricetinae; Enzyme Inhibitors; Flavonoids; Gene Expression; Gene Expression Regulation; Humans; Hydroquinones; Leupeptins; Maleates; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Proteasome Inhibitors; RNA, Messenger; Transfection | 2010 |
Serine 111 phosphorylation regulates OCT4A protein subcellular distribution and degradation.
Topics: Cell Line, Tumor; Fibroblast Growth Factor 2; Flavonoids; Gene Expression; Homeodomain Proteins; Humans; Immunoblotting; Immunoprecipitation; Kruppel-Like Transcription Factors; Leupeptins; MAP Kinase Kinase 1; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nanog Homeobox Protein; Octamer Transcription Factor-3; Phosphorylation; Protein Binding; Protein Isoforms; Proteolysis; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Serine; SOXB1 Transcription Factors; Ubiquitination | 2012 |