pd 98059 has been researched along with leukotriene b4 in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 6 (60.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuroki, M; O'Flaherty, JT | 1 |
| Barnes, PJ; Giembycz, MA; Haddad, EB; Hellewell, PG; Lindsay, MA; Rousell, J; Teixeira, MM | 1 |
| Buridi, A; Coxon, PY; Kettritz, R; Klein, JB; Manning, T; McLeish, KR; Rane, MJ | 1 |
| Barnes, PJ; Giembycz, MA; Lindsay, MA; Lynch, OT | 1 |
| Gilbert, AK; Pétrin, D; Rola-Pleszczynski, M; Stankova, J; Turcotte, S | 1 |
| Adrian, TE; Bell, RH; Ding, XZ; Talamonti, MS; Tong, WG | 1 |
| Bonanno, A; Bonsignore, G; Bousquet, J; Giorgi, RD; Gjomarkaj, M; Mirabella, F; Profita, M; Riccobono, L; Sala, A; Vignola, AM | 1 |
| Hide, M; Hiragun, T; Koro, O; Morita, E; Okabe, T; Yamamoto, S | 1 |
| Cai, L; Hao, H; Li, HH; Miao, S; Tang, K; Wu, L; Wu, P; Wu, Q; Xiong, J; Ye, DY; Zeng, P; Zou, LB | 1 |
| Kim, S; Lee, CH; Lee, HJ; Park, MK; Park, Y; Shim, J | 1 |
10 other study(ies) available for pd 98059 and leukotriene b4
| Article | Year |
|---|---|
Differential effects of a mitogen-activated protein kinase kinase inhibitor on human neutrophil responses to chemotactic factors.
Topics: Chemotactic Factors; Complement C5a; Enzyme Activation; Flavonoids; Humans; Interleukin-8; Leukotriene B4; Mitogen-Activated Protein Kinase Kinases; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Protein Kinase Inhibitors; Protein Kinases | 1997 |
Role of the mitogen-activated protein kinases and tyrosine kinases during leukotriene B4-induced eosinophil activation.
Topics: Animals; Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Flavonoids; Guinea Pigs; JNK Mitogen-Activated Protein Kinases; Kinetics; Lactams, Macrocyclic; Leukotriene B4; Male; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Peritoneal Cavity; Phenols; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Quinones; Rifabutin | 1998 |
Role of extracellular signal-regulated kinase and phosphatidylinositol-3 kinase in chemoattractant and LPS delay of constitutive neutrophil apoptosis.
Topics: Androstadienes; Apoptosis; Chemotaxis, Leukocyte; Chromones; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Leukotriene B4; Lipopolysaccharides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Morpholines; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Virulence Factors, Bordetella; Wortmannin | 2001 |
Pharmacological comparison of LTB(4)-induced NADPH oxidase activation in adherent and non-adherent guinea-pig eosinophils.
Topics: Androstadienes; Animals; Antibodies; Carbazoles; CD18 Antigens; Cell Adhesion; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Eosinophils; Flavonoids; Guinea Pigs; Imidazoles; Indoles; Integrin beta1; Intracellular Signaling Peptides and Proteins; Leukotriene B4; Macrophage-1 Antigen; Male; Maleimides; Mitogen-Activated Protein Kinases; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Pyrimidines; Rats; src-Family Kinases; Stilbenes; Syk Kinase; Time Factors; Wortmannin | 2001 |
The anti-apoptotic effect of leukotriene B4 in neutrophils: a role for phosphatidylinositol 3-kinase, extracellular signal-regulated kinase and Mcl-1.
Topics: Androstadienes; Apoptosis; bcl-2-Associated X Protein; Cell Survival; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation; Humans; Kinetics; Leukotriene B4; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Neutrophils; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-bcl-2; Reference Values; RNA, Messenger; Signal Transduction; Time Factors; Wortmannin | 2006 |
LTB4 stimulates growth of human pancreatic cancer cells via MAPK and PI-3 kinase pathways.
Topics: Androstadienes; Arachidonate 5-Lipoxygenase; Benzoates; Butadienes; Cell Division; Cell Line, Tumor; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Flavonoids; Humans; Leukotriene B4; Mitogen-Activated Protein Kinases; Nitriles; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Signal Transduction; Wortmannin | 2005 |
Muscarinic receptors, leukotriene B4 production and neutrophilic inflammation in COPD patients.
Topics: Acetylcholine; Aged; Calcium-Binding Proteins; Cells, Cultured; Chemotaxis, Leukocyte; Female; Flavonoids; Humans; Immunohistochemistry; Leukocytes, Mononuclear; Leukotriene B4; Male; Middle Aged; Mitogen-Activated Protein Kinase 3; Neutrophils; Protozoan Proteins; Pulmonary Disease, Chronic Obstructive; Receptors, Muscarinic; Sputum | 2005 |
Bone marrow derived mast cell acquire responsiveness to substance P with Ca(2+) signals and release of leukotriene B(4) via mitogen-activated protein kinase.
Topics: Animals; Bone Marrow Cells; Calcium; Calcium Signaling; Coculture Techniques; Enzyme Inhibitors; Fibroblasts; Flavonoids; Histamine Release; Imidazoles; Leukotriene B4; Male; Mast Cells; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; NIH 3T3 Cells; Pyridines; Species Specificity; Substance P | 2006 |
Lipoxin A4 inhibits 5-lipoxygenase translocation and leukotrienes biosynthesis to exert a neuroprotective effect in cerebral ischemia/reperfusion injury.
Topics: Animals; Animals, Newborn; Arachidonate 5-Lipoxygenase; Astrocytes; Brain Edema; Brain Ischemia; Disease Models, Animal; Enzyme Inhibitors; Flavonoids; Glucose; Leukotriene B4; Leukotriene C4; Leukotrienes; Lipoxins; Male; MAP Kinase Signaling System; Neuroprotective Agents; Oxygen; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger | 2012 |
Novel involvement of leukotriene B₄ receptor 2 through ERK activation by PP2A down-regulation in leukotriene B₄-induced keratin phosphorylation and reorganization of pancreatic cancer cells.
Topics: Anesthetics, Inhalation; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Down-Regulation; Enzyme Activation; Ethers; Flavonoids; Flow Cytometry; Fluorescent Antibody Technique; Humans; Hydrocarbons, Fluorinated; Immunoprecipitation; Keratin-8; Leukotriene B4; Mitogen-Activated Protein Kinase 3; Pancreatic Neoplasms; Phosphorylation; Protein Phosphatase 2; Receptors, Leukotriene B4; RNA, Messenger; RNA, Small Interfering; Serine; Signal Transduction; Tumor Cells, Cultured | 2012 |