pd 98059 and h 89

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides

Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

Topics: Acetylcholine; Animals; Arachidonic Acid; Brain Chemistry; Chick Embryo; Cycloheximide; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Genistein; Indoles; Indomethacin; Ion Channel Gating; Isoquinolines; Maleimides; Masoprocol; Membrane Potentials; Mutagenesis, Site-Directed; Oocytes; Patch-Clamp Techniques; Phosphorylation; Protein Kinase C; Protein Synthesis Inhibitors; Rats; Receptors, Nicotinic; Sulfonamides; Torpedo; Xenopus

Topics: Animals; Calcimycin; Carcinogens; Cells, Cultured; Cholera Toxin; Cyclic AMP; Endothelial Growth Factors; Enzyme Activation; Enzyme Inhibitors; Fetus; Flavonoids; Ionophores; Isoquinolines; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Palate; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Fetus; Flavonoids; Hepatocyte Growth Factor; Isoenzymes; Isoquinolines; Naphthalenes; Neocortex; Neurons; Phospholipase C gamma; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Proto-Oncogene Proteins c-met; Rats; Rats, Wistar; Signal Transduction; Subcellular Fractions; Substrate Specificity; Sulfonamides; Type C Phospholipases

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Animals, Newborn; Astrocytes; Cells, Cultured; Cerebral Cortex; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Dinoprostone; Enkephalins; Enzyme Inhibitors; Flavonoids; Imidazoles; Isoquinolines; Kinetics; Nimodipine; omega-Conotoxin GVIA; Peptides; Phosphorylation; Protein Precursors; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; RNA, Messenger; Staurosporine; Sulfonamides; Transcription Factor AP-1; Transcription, Genetic

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colforsin; Corticotropin-Releasing Hormone; Cyclic AMP; DNA Replication; Enzyme Inhibitors; Flavonoids; Isoquinolines; Mice; Pituitary Gland, Anterior; Pituitary Neoplasms; Sheep; Sulfonamides; Thymidine

Topics: Animals; Arachidonic Acid; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Flavonoids; Indoles; Ion Channel Gating; Isoquinolines; Kainic Acid; Maleimides; Oocytes; Patch-Clamp Techniques; Protein Kinase C; Receptors, AMPA; RNA, Messenger; Signal Transduction; Sulfonamides; Xenopus

Topics: Alkaloids; Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cells, Cultured; Cyclic GMP; Dibutyryl Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Indoles; Isoquinolines; Male; Naphthalenes; Natriuretic Peptide, C-Type; Neurosecretory Systems; Nitroprusside; Phosphodiesterase Inhibitors; Phosphorylation; Pineal Gland; Protein Kinase C; Purinones; Rats; Rats, Sprague-Dawley; Sulfhydryl Reagents; Sulfonamides; Thionucleotides

Topics: Androstadienes; Blood Proteins; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chondrocytes; Collagen; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Flavonoids; Humans; Imidazoles; Isoquinolines; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutation; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Pyridines; Signal Transduction; Sulfonamides; Transcriptional Activation; Transfection; Wortmannin

Topics: Arachidonic Acid; Bronchi; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Carboxylic Acids; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Eicosanoids; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Fumonisins; Humans; Isoquinolines; Naphthalenes; Phospholipases A; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Signal Transduction; Sphingolipids; Sulfonamides

Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Line; Enzyme Inhibitors; Flavonoids; Indoles; Isoquinolines; Kinetics; Lysophosphatidylcholines; Myocardium; Nimodipine; Phospholipases A; Protein Kinase C; Rats; Staurosporine; Structure-Activity Relationship; Sulfonamides

Topics: Amidines; Animals; Benzylamines; Calcium Signaling; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Line; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Drug Design; Enzyme Inhibitors; Flavonoids; Imidazoles; Indole Alkaloids; Isoquinolines; Lipopolysaccharides; Mice; Microglia; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Phosphorylation; Pyridines; Staurosporine; Sulfonamides

Topics: 3T3 Cells; Adipocytes; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanolamines; Flavonoids; Glycerol; Isoquinolines; Mice; Mitogen-Activated Protein Kinases; Phosphorylation; Propanolamines; Propranolol; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Sulfonamides; Tetrahydronaphthalenes

Topics: Adenocarcinoma; Androstadienes; Antineoplastic Agents, Hormonal; Chorionic Gonadotropin; Cyclic AMP; Cyclooxygenase 2; Endometrial Neoplasms; Enzyme Activation; Enzyme Inhibitors; Estradiol; Female; Flavonoids; Humans; Isoenzymes; Isoquinolines; Medroxyprogesterone Acetate; Membrane Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mitogens; Platelet Activating Factor; Prostaglandin-Endoperoxide Synthases; Protein Kinase Inhibitors; Signal Transduction; Sulfonamides; Thionucleotides; Tumor Cells, Cultured; Wortmannin

Topics: Adenocarcinoma; Androstadienes; Breast Neoplasms; Butadienes; Chromones; Culture Media, Serum-Free; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Depression, Chemical; DNA Replication; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Flavonoids; Fulvestrant; Humans; Isoquinolines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitosis; Morpholines; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Retinoblastoma Protein; Sulfonamides; Wortmannin

Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Division; Cell Line; Cell Survival; Chromones; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytosol; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Activation; Enzyme Inhibitors; Epithelium; Fibroblasts; Flavonoids; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Intestinal Mucosa; Isoquinolines; Microscopy, Fluorescence; Mitochondria; Morpholines; Peptides; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Receptors, Cell Surface; Receptors, Glucagon; Signal Transduction; Sulfonamides; Time Factors; Transfection

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adjuvants, Immunologic; Animals; Butadienes; Cell Line; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Inhibitors; Extracellular Space; Flavonoids; Gene Expression; Indoles; Isoquinolines; Maleimides; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neuropeptides; Nitriles; Pituitary Adenylate Cyclase-Activating Polypeptide; Pituitary Gland; Prolactin; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptor Cross-Talk; RNA, Messenger; Sulfonamides; Thyrotropin-Releasing Hormone; Vasoactive Intestinal Peptide

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Actins; Animals; Calcium; Cell Size; CHO Cells; Colforsin; Cricetinae; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Fluorescent Dyes; Glutamic Acid; GTP-Binding Protein alpha Subunits, Gs; Isoquinolines; MAP Kinase Signaling System; Protein Kinase C; Receptors, Metabotropic Glutamate; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Transfection; Type C Phospholipases

Topics: Adenocarcinoma; Cyclooxygenase 2; Dinoprostone; Endometrial Neoplasms; Enzyme Activation; Enzyme Inhibitors; Female; Flavonoids; Gene Expression; Humans; Immunohistochemistry; Isoenzymes; Isoquinolines; Kinetics; Membrane Proteins; Mitogen-Activated Protein Kinases; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sulfonamides; Tumor Cells, Cultured

Topics: Blotting, Northern; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Insulin-Like Growth Factor Binding Protein 1; Interleukin-1; Isoquinolines; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Radioimmunoassay; RNA, Messenger; Signal Transduction; Stimulation, Chemical; Sulfonamides; Tumor Cells, Cultured

Topics: Animals; Cadherins; Carbazoles; Cartilage; Cell Differentiation; Chick Embryo; Chondrogenesis; Cyclic AMP-Dependent Protein Kinases; Embryonic Induction; Enzyme Inhibitors; Fibronectins; Flavonoids; Indoles; Isoenzymes; Isoquinolines; Mesoderm; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Kinase C; Protein Kinase C-alpha; Pyrroles; Receptors, Fibronectin; Signal Transduction; Sulfonamides

Topics: Animals; Apoptosis; Brain Chemistry; Calcium-Calmodulin-Dependent Protein Kinases; Cell Fractionation; Cell Survival; Cells, Cultured; Cerebellum; Colforsin; Culture Media, Serum-Free; Cyclic AMP; Enzyme Inhibitors; Flavonoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Immunoblotting; Isoquinolines; Neurons; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Fusion Proteins; Sulfonamides; Transfection

Topics: Activating Transcription Factor 1; Animals; Cattle; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cyclooxygenase 2; DNA-Binding Proteins; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Imidazoles; Indoles; Isoenzymes; Isoquinolines; Lysophosphatidylcholines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Pyridines; RNA, Messenger; Sulfonamides; Transcription Factors; Up-Regulation

Topics: Animals; Binding Sites; Colforsin; CREB-Binding Protein; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; E1A-Associated p300 Protein; Enzyme Inhibitors; Epidermal Growth Factor; ets-Domain Protein Elk-1; Flavonoids; Isoquinolines; Mitogen-Activated Protein Kinases; Nuclear Proteins; Pituitary Neoplasms; Potassium Channels; Prolactin; Promoter Regions, Genetic; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; rap1 GTP-Binding Proteins; Rats; Sulfonamides; Thyrotropin-Releasing Hormone; Trans-Activators; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured

Topics: Animals; Arachidonic Acid; Cation Transport Proteins; Cells, Cultured; Cholecystokinin; Colforsin; DNA-Binding Proteins; Enzyme Inhibitors; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Flavonoids; Humans; Indoles; Isoquinolines; Kinetics; Maleimides; Membrane Potentials; Membrane Transport Proteins; Patch-Clamp Techniques; Pituitary Gland, Anterior; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Kinase Inhibitors; Protein Kinases; Rats; Signal Transduction; Sulfonamides; Tetradecanoylphorbol Acetate; Thyrotropin-Releasing Hormone; Trans-Activators; Transcriptional Regulator ERG; Tyrphostins; Vasoactive Intestinal Peptide

Topics: Animals; Colforsin; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Glioma; Imidazoles; Isoquinolines; Lipopolysaccharides; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; RNA, Messenger; Sulfonamides; Transcription, Genetic; Tumor Cells, Cultured

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Astrocytes; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Cycloheximide; Enkephalins; Enzyme Inhibitors; Flavonoids; Gene Expression; Imidazoles; Isoquinolines; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Protein Precursors; Protein Synthesis Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sphingosine; Stimulation, Chemical; Sulfonamides; Transcription Factor AP-1

Topics: Apoptosis; bcl-2-Associated X Protein; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Caspases; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Cytochrome c Group; Cytosol; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Etoposide; Flavonoids; Gene Expression Regulation; Humans; In Situ Nick-End Labeling; Infant, Newborn; Isoquinolines; Mitochondria; Mitogen-Activated Protein Kinases; Naphthalenes; Neoplasm Proteins; Osteoblasts; Protein Kinase C; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Recombinant Proteins; Signal Transduction; Skull; Smad Proteins; Smad1 Protein; Sulfonamides; Trans-Activators; Transcription Factors; Transforming Growth Factor beta

Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Androstadienes; Animals; Anti-Bacterial Agents; Benzoquinones; Cell Differentiation; Chromones; Cyclic AMP; Enzyme Inhibitors; Flavonoids; Gene Expression; Glial Fibrillary Acidic Protein; Glioma; Indoles; Isoproterenol; Isoquinolines; Lactams, Macrocyclic; Maleimides; Morpholines; Phosphatidylinositol 3-Kinases; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Sirolimus; Sulfonamides; Tumor Cells, Cultured; Wortmannin

Topics: Acetylcysteine; Androstadienes; Animals; Cyclic N-Oxides; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Indoles; Isoquinolines; Kinetics; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neurites; Neuroprotective Agents; Nitrogen Oxides; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Protein Kinase C; ras Proteins; Rats; Recombinant Proteins; Signal Transduction; Sulfonamides; Transfection; Wortmannin

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Division; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Gene Expression; Isoquinolines; Kidney Tubules, Collecting; Mice; Phenotype; Polycystic Kidney Diseases; Proteins; Recombinant Fusion Proteins; RNA, Messenger; Signal Transduction; Sulfonamides; Transfection; TRPP Cation Channels

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Blood Flow Velocity; Bucladesine; Calcium-Calmodulin-Dependent Protein Kinases; Cardiovascular Agents; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Dogs; Enzyme Inhibitors; Flavonoids; Hemodynamics; Imidazoles; Indoles; Isoquinolines; Maleimides; Milrinone; Mitogen-Activated Protein Kinases; Myocardial Infarction; p38 Mitogen-Activated Protein Kinases; Phosphodiesterase Inhibitors; Protein Kinase C; Pyridines; Pyridones; Sulfonamides; Ventricular Fibrillation

Topics: Active Transport, Cell Nucleus; Animals; Apoptosis; Cell Nucleus; Cells, Cultured; Cerebral Cortex; Cytoplasm; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Flavonoids; Genistein; Glutamic Acid; Isoquinolines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Neurotoxins; Phosphoprotein Phosphatases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Sphingosine; Sulfonamides; Vanadates

Topics: Androstadienes; Benzylamines; Cell Line; Colforsin; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Epithelial Cells; Flavonoids; Genistein; Humans; Indoles; Interleukin-8; Isoquinolines; Lung; Maleimides; Okadaic Acid; Pertussis Toxin; Protein Kinase C; Signal Transduction; Sodium Fluoride; Sulfonamides; Tetradecanoylphorbol Acetate; Vanadates; Virulence Factors, Bordetella; Wortmannin

Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbazoles; Chromones; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation; Hemocytes; HSP70 Heat-Shock Proteins; Indoles; Isoproterenol; Isoquinolines; Luciferases; Morpholines; Naphthalenes; Norepinephrine; Ostreidae; Pertussis Toxin; Phenylephrine; Phosphodiesterase Inhibitors; Prazosin; Promoter Regions, Genetic; Propranolol; Pyrrolidinones; Signal Transduction; Sulfonamides; Transfection; Virulence Factors, Bordetella

Topics: Androstadienes; Carrier Proteins; Eukaryotic Initiation Factor-4E; Flavonoids; Imidazoles; Isoquinolines; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Pyridines; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 90-kDa; Sirolimus; Sulfonamides; Ultraviolet Rays; Wortmannin

Topics: Animals; Cell Line; Cyclic AMP-Dependent Protein Kinases; Dopamine; Dopamine Antagonists; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Isoquinolines; Kidney; MAP Kinase Signaling System; Naphthalenes; Opossums; Parathyroid Hormone; Pertussis Toxin; Phosphodiesterase Inhibitors; Phospholipases A; Protein Kinase C; Pyrones; Sodium-Potassium-Exchanging ATPase; Sulfonamides; Virulence Factors, Bordetella

Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bucladesine; Carbazoles; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Genistein; Indoles; Isoquinolines; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phosphorylation; Plasminogen Activator Inhibitor 1; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Rats; Signal Transduction; src-Family Kinases; Stilbenes; Sulfonamides; Tissue Plasminogen Activator; Urokinase-Type Plasminogen Activator

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Alloxan; Androstadienes; Apoptosis; Arginase; B-Lymphocytes; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chelating Agents; Cyclic AMP-Dependent Protein Kinases; Deoxyglucose; Egtazic Acid; Enzyme Inhibitors; Flavonoids; Gastric Inhibitory Polypeptide; Genistein; Glucokinase; Glucose; Humans; Indoles; Isoquinolines; Maleimides; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitosis; Phosphoinositide-3 Kinase Inhibitors; Plasmids; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; Sulfonamides; Wortmannin

Topics: 1-Methyl-3-isobutylxanthine; Alkaloids; Amino Acid Motifs; Benzophenanthridines; Bucladesine; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Female; Fetal Blood; Flavonoids; Follicular Fluid; Humans; Isoquinolines; Male; MAP Kinase Kinase Kinase 1; Phenanthridines; Phosphorylation; Progesterone; Protein Kinase C; Protein Serine-Threonine Kinases; Seminal Plasma Proteins; Signal Transduction; Sperm Capacitation; Sulfonamides; Tyrosine; Tyrphostins

Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipocytes; Adult; Antineoplastic Agents; Butadienes; Carrier Proteins; Cell Differentiation; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic Nucleotide Phosphodiesterases, Type 3; Enzyme Inhibitors; Female; Flavonoids; Humans; Isoquinolines; Lipolysis; Male; MAP Kinase Kinase 2; MAP Kinase Signaling System; Middle Aged; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Perilipin-1; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Sulfonamides; Tumor Necrosis Factor-alpha

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cell Differentiation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Flavonoids; HL-60 Cells; Humans; Isoquinolines; Lipopolysaccharide Receptors; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Phenotype; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-raf; Second Messenger Systems; Sulfonamides; Superoxides; Tetradecanoylphorbol Acetate

Topics: Animals; Apoptosis; Caspases; Cell Line; Chromones; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Isoquinolines; Macrophages; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Staurosporine; Sulfonamides

Topics: Animals; Butadienes; Cell Line; Cell Nucleus; Enzyme Inhibitors; Escherichia coli; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Isoquinolines; L Cells; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinases; Models, Biological; Mutation; NF-kappa B; Nitriles; Phosphorylation; Protein Subunits; Pyridines; Recombinant Proteins; Ribosomal Protein S6 Kinases, 90-kDa; Serine; Sulfonamides; Transcriptional Activation; Tumor Necrosis Factor-alpha

Topics: Antineoplastic Agents; Apoptosis; Butyrates; Caspases; Cyclic AMP Response Element-Binding Protein; Enzyme Inhibitors; Fibrosarcoma; Flavonoids; Humans; Isoquinolines; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Signal Transduction; Sulfonamides; Tumor Cells, Cultured

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Line; Cell Nucleus; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Isoquinolines; Male; Mice; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Neuregulins; Phosphorylation; Protein Subunits; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Recombinant Fusion Proteins; Sulfonamides; Synapses

Topics: Ascomycota; Cholera Toxin; Colforsin; Cyclic AMP; Enzyme Activators; Enzyme Inhibitors; Flavonoids; Hordeum; Hyphae; Isoquinolines; Mitogen-Activated Protein Kinases; Pertussis Toxin; Signal Transduction; Sphingosine; Sulfonamides; Time Factors

Topics: Animals; Aorta; Cells, Cultured; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Imidazoles; Imines; Indoles; Interleukin-6; Isoquinolines; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Protein Kinase C; Pyridines; Rats; Sulfonamides; Urocortins

Topics: Active Transport, Cell Nucleus; Animals; Calcium; Cell Differentiation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Flavonoids; Isoquinolines; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neurites; PC12 Cells; Phosphorylation; Potassium Chloride; Protein Serine-Threonine Kinases; Rats; Signal Transduction; Sulfonamides

Topics: Adenocarcinoma; Anticarcinogenic Agents; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Endometrial Neoplasms; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Flavonoids; Fulvestrant; Humans; Indoles; Isoquinolines; Ligands; MAP Kinase Signaling System; Phosphoprotein Phosphatases; Phosphorylation; Point Mutation; Sulfonamides; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured

Topics: Androstadienes; Blotting, Western; Cell Line; Chlorides; Chlorine; Colon; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Flavonoids; GTP-Binding Protein alpha Subunits, Gs; Humans; Ions; Isoquinolines; MAP Kinase Signaling System; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Protein Binding; Quinazolines; Sulfonamides; Time Factors; Transcriptional Activation; Tyrosine; Tyrphostins; Vasoactive Intestinal Peptide; Wortmannin

Topics: Animals; Calcitonin; CCAAT-Binding Factor; Cells, Cultured; Cloning, Molecular; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Genes, Reporter; Humans; Immunoglobulins; Isoquinolines; Mutation; Naphthalenes; Promoter Regions, Genetic; Protein Kinase C; Receptors, Calcitonin; Steroid Hydroxylases; Sulfonamides; Vitamin D3 24-Hydroxylase

Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cadmium; Cell Line, Tumor; Cell Survival; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Flavonoids; Gene Expression Regulation; Genes, Reporter; Humans; Immunohistochemistry; Inflammation; Isoquinolines; Lung; Mitogen-Activated Protein Kinases; Nuclear Receptor Subfamily 4, Group A, Member 1; Nucleic Acid Hybridization; Plasmids; Precipitin Tests; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sulfonamides; Time Factors; Transcription Factors; Transfection

Topics: Animals; Bumetanide; Butadienes; Cell Line; Chromones; Colforsin; Cyclic AMP; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Gastrointestinal Tract; Indoles; Isoproterenol; Isoquinolines; Maleimides; Mitogen-Activated Protein Kinases; Morpholines; Muscle, Skeletal; Nitriles; Potassium; Rats; Rubidium Radioisotopes; Sodium-Potassium-Chloride Symporters; Sulfonamides

Topics: Androgens; Animals; Autocrine Communication; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Flavonoids; Gene Expression Regulation; Isoquinolines; Leydig Cells; Luteinizing Hormone; Male; Mitogen-Activated Protein Kinases; Phosphoproteins; Quinazolines; Rats; RNA, Messenger; Steroids; Sulfonamides; Transforming Growth Factor alpha; Tyrphostins

Topics: Animals; Base Sequence; Benzylamines; Binding Sites; Bucladesine; Carbazoles; Cell Nucleus; CHO Cells; Cricetinae; Cyclic AMP; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; GATA6 Transcription Factor; Humans; Imidazoles; Indole Alkaloids; Isoquinolines; MAP Kinase Kinase Kinase 1; MAP Kinase Signaling System; Molecular Sequence Data; Mutation; Naphthalenes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Plasmids; Prostaglandin D2; Proteasome Endopeptidase Complex; Protein Binding; Pyridines; src-Family Kinases; Sulfonamides; Transcription Factors

Topics: Animals; Catecholamines; Cell Line, Tumor; Cyclic AMP-Dependent Protein Kinases; Flavonoids; Hypothalamic Hormones; Indoles; Isoquinolines; MAP Kinase Signaling System; Neuropeptides; Pheochromocytoma; Prolactin-Releasing Hormone; Protein Kinase C; Pyrroles; Rats; RNA, Messenger; Signal Transduction; Stimulation, Chemical; Sulfonamides; Tyrosine 3-Monooxygenase

Topics: Animals; Bucladesine; Caspase 3; Caspases; Cell Differentiation; Cell Survival; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Intracellular Membranes; Isoquinolines; MAP Kinase Signaling System; Membrane Potentials; Mitochondria; Nerve Growth Factors; Neurons; Neuropeptides; Neurosecretory Systems; Neurotransmitter Agents; p38 Mitogen-Activated Protein Kinases; Parkinson Disease; PC12 Cells; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Kinase Inhibitors; Rats; Rotenone; Signal Transduction; Sulfonamides

Topics: Animals; Base Sequence; Cell Line, Tumor; Colforsin; Connexins; Cyclic AMP; Cyclic AMP Response Element Modulator; Cyclic AMP-Dependent Protein Kinases; DNA-Binding Proteins; Down-Regulation; Flavonoids; Gap Junction delta-2 Protein; Glucose; Humans; Insulin-Secreting Cells; Isoquinolines; Mitogen-Activated Protein Kinases; Nifedipine; Promoter Regions, Genetic; Rats; Response Elements; RNA, Messenger; Sequence Deletion; Sulfonamides; Tetradecanoylphorbol Acetate

Topics: Adrenal Cortex Neoplasms; Alprostadil; Aromatase; Benzylamines; Cell Line, Tumor; Dinoprost; Dinoprostone; Epidermal Growth Factor; Exons; Flavonoids; Humans; Isoquinolines; Promoter Regions, Genetic; Prostaglandins; Prostaglandins A; Prostaglandins E; Protein Kinase Inhibitors; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Prostaglandin E, EP2 Subtype; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stimulation, Chemical; Sulfonamides

Topics: 3T3 Cells; Adipocytes; Animals; Colforsin; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dactinomycin; Flavonoids; Humans; Interleukin-6; Isoquinolines; Mice; Protein Synthesis Inhibitors; Signal Transduction; Sulfonamides; Thyroid Gland; Thyrotropin

Topics: Adiponectin; Animals; Butadienes; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Drug Interactions; Enzyme Activation; Flavonoids; Imidazoles; Isoquinolines; Leptin; Macrophages, Peritoneal; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 3; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Sulfonamides; Tumor Necrosis Factor-alpha

Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Basic Helix-Loop-Helix Transcription Factors; Benzylamines; Butadienes; Calcium Signaling; Carbazoles; Cell Hypoxia; Cell Line; Cycloheximide; Flavonoids; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indoles; Ionomycin; Isoquinolines; Kidney; Nitriles; PC12 Cells; Polyribosomes; Protein Biosynthesis; Protein Kinase C-alpha; Protein Kinases; Protein Synthesis Inhibitors; Rats; RNA Caps; RNA, Messenger; RNA, Small Interfering; Sirolimus; Sulfonamides; TOR Serine-Threonine Kinases

Topics: Adenylyl Cyclases; Androstadienes; Animals; Animals, Newborn; Cell Line; Cell Proliferation; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Enzyme Activation; Flavonoids; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Human Growth Hormone; Imidazoles; Insulin-Secreting Cells; Isoquinolines; Liraglutide; Mitogen-Activated Protein Kinase Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Rats; Signal Transduction; Stimulation, Chemical; Sulfonamides; Transcription, Genetic; Transduction, Genetic; Wortmannin

Topics: Animals; Blotting, Western; Cell Line; Cell Proliferation; Colforsin; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Dose-Response Relationship, Drug; Exenatide; Flavonoids; Gene Expression; Glucagon-Like Peptide-1 Receptor; Insulin-Secreting Cells; Isoquinolines; Mitogen-Activated Protein Kinase Kinases; Mutagenesis, Site-Directed; Peptides; Phosphorylation; Proto-Oncogene Proteins c-raf; Rats; Rats, Sprague-Dawley; Receptors, Glucagon; Response Elements; RNA, Messenger; Sulfonamides; Venoms

Topics: Adiponectin; Cell Proliferation; Chemokine CCL2; Cytokines; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Granulocyte-Macrophage Colony-Stimulating Factor; HT29 Cells; Humans; Imidazoles; Indoles; Interleukin-1; Interleukin-8; Intestinal Mucosa; Isoquinolines; Maleimides; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Sulfonamides; Sulfones

Topics: Animals; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Enzyme Activation; Flavonoids; Hydrogen Peroxide; I-kappa B Proteins; Imidazoles; Immunoblotting; Isoquinolines; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; Myoblasts, Skeletal; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Ribosomal Protein S6 Kinases, 90-kDa; Serine; src-Family Kinases; Sulfonamides

Topics: Animals; Apoptosis; Cell Line; Cell Survival; CREB-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Flavonoids; Gene Expression; Genes, bcl-2; Glucose; Islets of Langerhans; Isoquinolines; Male; Microscopy, Electron, Transmission; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; RNA, Messenger; RNA, Small Interfering; Sulfonamides; Transfection

Topics: 3T3-L1 Cells; Adipocytes; Adrenergic beta-3 Receptor Agonists; Animals; Cyclic AMP-Dependent Protein Kinases; Dioxoles; Enzyme Activation; ErbB Receptors; Estradiol; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Isoquinolines; Lipolysis; Mice; Quinazolines; Receptors, Adrenergic, beta-3; RNA, Small Interfering; src-Family Kinases; Sulfonamides; Tyrphostins

Topics: Animals; Aromatase; Blotting, Northern; Cattle; Cells, Cultured; Chromones; Cyclic AMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; Estradiol; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Follicle Stimulating Hormone; Follicular Phase; Granulosa Cells; Indoles; Insulin; Isoquinolines; Maleimides; MAP Kinase Signaling System; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; RNA, Messenger; Sulfonamides

Topics: Animals; Flavonoids; Furans; Humans; Indoles; Isoquinolines; Lignans; Magnetic Resonance Spectroscopy; Magnolia; Maleimides; Neurites; PC12 Cells; Plant Bark; Protein Kinase Inhibitors; Rats; Sulfonamides

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Anticonvulsants; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Cell Proliferation; Chelating Agents; Chlorocebus aethiops; Endorphins; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Isoquinolines; MAP Kinase Signaling System; Mice; Nifedipine; Protein Kinase Inhibitors; Sulfonamides; Verapamil

Topics: Cyclic AMP-Dependent Protein Kinases; Endocytosis; Flavonoids; Fluorescent Antibody Technique; Golgi Apparatus; Horseradish Peroxidase; HT29 Cells; Humans; Isoquinolines; Light; Mitogen-Activated Protein Kinases; Naphthalenes; Staurosporine; Sulfonamides

Topics: Adenoviridae; Annexin A5; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Cell Adhesion; Cells, Cultured; Cytochromes c; Dose-Response Relationship, Drug; Endothelial Cells; Epoprostenol; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Focal Adhesion Kinase 1; Genetic Vectors; Humans; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Isoquinolines; Mitochondria; Mitochondrial Proteins; Oxidants; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; ras Proteins; Signal Transduction; Sulfonamides; Time Factors; Transfection; Ubiquitins; X-Linked Inhibitor of Apoptosis Protein

Topics: Androstadienes; Animals; Apoptosis; Apoptosis Regulatory Proteins; Biological Transport; Cell Line; Chromones; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Immunohistochemistry; Indoles; Insulin-Like Growth Factor I; Isoquinolines; Male; Maleimides; Microscopy, Confocal; Mitogen-Activated Protein Kinase Kinases; Morpholines; Neurons; Oligonucleotides, Antisense; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Rats; Recombinant Proteins; Stroke; Sulfonamides; Wortmannin

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Bronchi; Cadherins; Calmodulin; Cell Line; Cell Proliferation; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression; Humans; Immunochemistry; Isoquinolines; Ki-67 Antigen; Models, Biological; Protein Kinase C; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sulfonamides; Vasoactive Intestinal Peptide; Wound Healing

Topics: Amino Acids, Branched-Chain; Animals; Arginine; Cell Line; Flavonoids; Gene Expression Regulation; Isoquinolines; Mice; Muscle Proteins; Phosphoproteins; Protein Kinases; RNA, Messenger; SKP Cullin F-Box Protein Ligases; Starvation; Sulfonamides; Time Factors; TOR Serine-Threonine Kinases; Tripartite Motif Proteins; Ubiquitin-Protein Ligases

Topics: Adipocytes; Animals; Carrier Proteins; Cell Differentiation; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Cytokine Receptor gp130; Extracellular Signal-Regulated MAP Kinases; Fatty Acids, Nonesterified; Female; Flavonoids; Gene Expression; Interleukin-6; Isoquinolines; Lipolysis; Male; MAP Kinase Signaling System; Oxidation-Reduction; Perilipin-1; Phosphoproteins; PPAR gamma; Protein Kinase Inhibitors; Sulfonamides; Sus scrofa; Transcription Factors

Topics: Animals; Carbazoles; Cell Line; Flavonoids; HSP70 Heat-Shock Proteins; Humans; Indoles; Isoquinolines; Maleimides; MAP Kinase Signaling System; Mice; NFATC Transcription Factors; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Protein Transport; Saline Solution, Hypertonic; Signal Transduction; Sulfonamides

Topics: Anthracenes; Cell Line; Chromones; Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Flavonoids; Genes, Reporter; Humans; Hypothalamus; Imidazoles; Isoquinolines; Morpholines; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyridines; Regulatory Elements, Transcriptional; Sequence Deletion; Sulfonamides; Transfection

Topics: 3T3 Cells; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cells, Cultured; Colforsin; Enzyme Activation; Flavonoids; Interleukin-6; Isoquinolines; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Osteoblasts; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Sulfonamides; Tumor Necrosis Factor-alpha; Vasoactive Intestinal Peptide

Topics: Adenosine Triphosphate; Animals; Autophagy; Bucladesine; Cell Count; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Knockdown Techniques; Humans; Isoquinolines; Mice; Microtubule-Associated Proteins; Phosphorylation; Sirolimus; Sulfonamides; TOR Serine-Threonine Kinases

Topics: Adrenal Medulla; Animals; Benzylamines; Carbachol; Catecholamines; Cells, Cultured; Chromaffin Cells; Cyclic AMP-Dependent Protein Kinases; Deer; Flavonoids; Isoquinolines; Nicotinic Agonists; Phosphorylation; Protein Kinase Inhibitors; Receptors, Nicotinic; Sulfonamides; Tyrosine 3-Monooxygenase; Up-Regulation

Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Conditioning, Psychological; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Injections, Intraventricular; Isoquinolines; Male; Mice; Mitogen-Activated Protein Kinases; N-Methylaspartate; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Seizures; Signal Transduction; Sulfonamides; Wortmannin

Topics: 14-alpha Demethylase Inhibitors; 8,11,14-Eicosatrienoic Acid; Arachidonic Acid; Cell Cycle; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Chromones; Cyclic AMP-Dependent Protein Kinases; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Eicosanoids; Enzyme Inhibitors; Flavonoids; Gene Expression; Genes, Reporter; Humans; Isoquinolines; Ketoconazole; Luciferases; Mitogen-Activated Protein Kinases; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Quinidine; RNA; Sulfonamides; Transfection

Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aldosterone; Animals; Chelating Agents; Diglycerides; Egtazic Acid; Enzyme Inhibitors; Estrenes; Flavonoids; GTP-Binding Proteins; Humans; Isoquinolines; Kidney Tubules, Collecting; Male; Mice; Mice, Inbred C57BL; Pertussis Toxin; Protein Kinase C; Pyrrolidinones; Signal Transduction; Sulfonamides; Suramin; Type C Phospholipases; Vacuolar Proton-Translocating ATPases

Topics: Breast Neoplasms; Catalytic Domain; Chromatin; Colforsin; Cyclic AMP-Dependent Protein Kinases; Estrogens; Female; Flavonoids; Histone Demethylases; Histones; Humans; Isoquinolines; MAP Kinase Signaling System; MCF-7 Cells; Methylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Sulfonamides; Transcription, Genetic; Tretinoin

Topics: Animals; Antigens, Differentiation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Electromagnetic Fields; Flavonoids; Isoquinolines; MAP Kinase Signaling System; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinase 3; Osteogenesis; Rats; Rats, Sprague-Dawley; Sulfonamides

Topics: Animals; Animals, Newborn; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Enzyme Inhibitors; Flavonoids; Gene Knockdown Techniques; Hypoxia; Immediate-Early Proteins; Isoquinolines; Models, Animal; Morpholines; Myocytes, Cardiac; Peptide Fragments; Peptides, Cyclic; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rats; Real-Time Polymerase Chain Reaction; Receptors, Corticotropin-Releasing Hormone; Reperfusion Injury; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Sulfonamides; Urocortins

Topics: Apoptosis; Autocrine Communication; Caspase 3; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 2; Dinoprostone; Flavonoids; HL-60 Cells; Humans; Indomethacin; Isoquinolines; Lamin Type B; Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; RNA Interference; RNA, Small Interfering; Signal Transduction; Sulfonamides; Vitamin K 3

Topics: Animals; Butadienes; Cell Differentiation; Cell Proliferation; Chromones; Cyclic AMP-Dependent Protein Kinases; Embryo, Mammalian; Epithelial Cells; Epithelial-Mesenchymal Transition; Fixatives; Flavonoids; Formaldehyde; Gene Expression Regulation, Developmental; Isoquinolines; Ki-67 Antigen; Mice; Mice, Inbred ICR; Morpholines; Nitriles; Organ Culture Techniques; Paraffin Embedding; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polymers; Signal Transduction; Sulfonamides; Tongue

Topics: 8-Bromo Cyclic Adenosine Monophosphate; CD13 Antigens; Cell Differentiation; Cell Proliferation; Cyclic AMP-Dependent Protein Kinases; Endometrium; Epithelial Cells; Estradiol; Female; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; Insulin-Like Growth Factor Binding Protein 1; Intercellular Signaling Peptides and Proteins; Isoquinolines; Keratins; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Primary Cell Culture; Prolactin; Pyridines; Signal Transduction; Stromal Cells; Sulfonamides; Tetraspanin 29; Umbilical Cord; Vimentin; Wharton Jelly

Topics: Animals; Cell Line; Chorionic Gonadotropin; Flavonoids; Gene Expression Regulation; Insulin; Isoquinolines; Leydig Cells; Male; Mice; Nuclear Receptor Subfamily 4, Group A, Member 1; Perylene; Proteins; Signal Transduction; Sulfonamides; Testosterone; Wortmannin