Compounds > pd 98059

pd 98059 and go 6976

pd 98059 has been researched along with go 6976 in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (13.51)18.2507
2000's24 (64.86)29.6817
2010's8 (21.62)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Caivano, M; Cohen, P; Davies, SP; Reddy, H1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A1
Baumruker, T; Csonga, R; Jaksche, D; Novotny, V; Prieschl, EE1
Alexander, JS; Kevil, CG; Mire, E; Payne, DK1
Shibuya, M; Takahashi, T; Ueno, H1
Henrion, D; Lehoux, S; Lévy, BI; Loufrani, L; Tedgui, A1
Alexander, JS; Battarbee, H; Gute, D; Krsmanovic, A; Okayama, N; Park, JH1
Alexander, BC; Alexander, JS; Carden, DL; Davis, CP; Eppihimer, LA; Goodyear, N; Haque, R; Kalogeris, TJ; Kevil, CG; Zhu, YN1
Akkerman, JW; Gorter, G; van Willigen, G1
Joe, E; Jou, I; Pyo, H; Ryu, J1
Chen, H; Fetscher, C; Heusch, G; Michel, MC; Schäfers, RF; Wambach, G1
Chang, LC; Wang, JP1
Chen, Y; Jing, Q; Li, X; Pei, G; Qiu, J; Sun, G; Wang, P; Zhang, W; Zhong, Y1
Barnes, PJ; Giembycz, MA; Lindsay, MA; Lynch, OT1
Cueff, A; De Cian, MC; Lacoste, A; Poulet, SA1
Blomhoff, HK; Myklebust, JH; Rusten, LS; Smeland, EB; Stokke, T1
Chain, BM; Cho, JY; Katz, DR1
Farnell, MB; Genovese, K; He, H; Kogut, MH1
Chang, YY; Sun, SH; Wang, CM1
Chang, YH; Chi, KH; Chio, CC; Hsu, YW; Lin, WW1
Chun, JS; Jeon, HB; Lee, JH; Lee, SJ; Yoo, JS; Yoo, YJ1
Honda, Y; Kemmochi, S; Miyamoto, N; Oh, H; Ohashi, H; Ojima, T; Sato, Y; Suganami, E; Suzuma, I; Suzuma, K; Takagi, H; Uemura, A; Watanabe, D1
Cruciani, V; Flørenes, VA; Jørgensen, K; Mikalsen, SO; Skrede, M; Slipicevic, A1
Bauer, AL; Czyzyk-Krzeska, MF; Hui, AS; Schnell, PO; Striet, JB1
Amiel, S; Asare-Anane, H; Gray, E; Huang, GC; Jones, PM; Muller, D; Persaud, SJ; Squires, PE1
Ji, Y; Lee, HJ; Maehr, H; Paul, S; Suh, N; Uskokovic, M1
Huang, TQ; Lee, JS; Lim, YS; Seo, JS1
Ansari, HR; Martin, KH; Mustafa, SJ; Nadeem, A; Roush, KP; Schnermann, J; Teng, B1
Kanai, T; Maruta, T; Miyazaki, S; Nemoto, T; Satoh, S; Wada, A; Yanagita, T; Yoshikawa, N1
Carlson, M; Lampinen, M; Venge, P1
Fang, J; Huang, J; Li, C; Li, Z; Tian, F; Wang, N; Xie, F1
Aravena, C; Beltrán, AR; Cornejo, M; Díaz, ES; Guzmán-Gutiérrez, E; Leiva, A; Pardo, F; Ramírez, MA; Sobrevia, L; Torres, V1
Dick, GM; Kunduri, SS; Mustafa, SJ; Nayeem, MA; Ponnoth, DS1
Aoki, M; Hirose, E; Ishimaru, Y; Kawata, J; Matsmoto, T; Narahara, S; Ono, T; Sagara, K; Yamaguchi, Y1
Chidipi, B; Kim, JC; Kim, KH; Kim, SW; Son, MJ; Subedi, KP; Wang, J; Woo, SH1

Other Studies

37 other study(ies) available for pd 98059 and go 6976

ArticleYear
Specificity and mechanism of action of some commonly used protein kinase inhibitors.
    The Biochemical journal, 2000, Oct-01, Volume: 351, Issue:Pt 1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Acetophenones; Alkaloids; Amides; Animals; Benzamides; Benzophenanthridines; Benzopyrans; Butadienes; Cell Line; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Indoles; Inhibitory Concentration 50; Isoquinolines; Lithium; Magnesium; Nitriles; Phenanthridines; Phosphorylation; Potassium Chloride; Protein Kinase Inhibitors; Protein Kinases; Pyridines; Sirolimus; Substrate Specificity; Sulfonamides

2000
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2

    Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

2013
Common and distinct signaling pathways mediate the induction of TNF-alpha and IL-5 in IgE plus antigen-stimulated mast cells.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Jan-01, Volume: 160, Issue:1

    Topics: Animals; Antigens; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cells, Cultured; Chamomile; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Immunoglobulin E; Indoles; Interleukin-5; Mast Cells; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NFATC Transcription Factors; Nuclear Proteins; Oils, Volatile; Plants, Medicinal; Promoter Regions, Genetic; Protein Kinase C; Signal Transduction; Transcription Factors; Tumor Necrosis Factor-alpha

1998
Vascular permeability factor/vascular endothelial cell growth factor-mediated permeability occurs through disorganization of endothelial junctional proteins.
    The Journal of biological chemistry, 1998, Jun-12, Volume: 273, Issue:24

    Topics: Androstadienes; Antigens, CD; Cadherins; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Membrane Permeability; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Histocytochemistry; Humans; Indoles; Lymphokines; Membrane Proteins; Muscle, Smooth, Vascular; Nitriles; Occludin; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Serum Albumin; Staurosporine; Tyrphostins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin

1998
VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells.
    Oncogene, 1999, Apr-01, Volume: 18, Issue:13

    Topics: 3T3 Cells; Adenoviridae; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Chromones; DNA Replication; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genes, ras; Genetic Vectors; Indoles; Lymphokines; Maleimides; MAP Kinase Kinase Kinase 1; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Isoforms; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Rats; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Tetradecanoylphorbol Acetate; Transfection; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; Wortmannin

1999
Stretch induces mitogen-activated protein kinase activation and myogenic tone through 2 distinct pathways.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:12

    Topics: Animals; Benzoquinones; Carbazoles; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix; Flavonoids; Genistein; Indoles; Lactams, Macrocyclic; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle Tonus; Protein Kinase C; Quinones; Rabbits; Rifabutin; Temperature; Vasoconstriction; Veins

1999
Hypoxia/aglycemia increases endothelial permeability: role of second messengers and cytoskeleton.
    The American journal of physiology, 1999, Volume: 277, Issue:6

    Topics: Alkaloids; beta Catenin; Cadherins; Calcium; Calcium Channel Blockers; Calcium Signaling; Carbazoles; Cell Hypoxia; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Cyclic GMP-Dependent Protein Kinases; Cytoskeletal Proteins; Cytoskeleton; Dermis; Endothelium; Enzyme Inhibitors; Flavonoids; Gallic Acid; Glucose; Humans; Indoles; Intercellular Junctions; Isoenzymes; Membrane Proteins; Microspheres; Mitogen-Activated Protein Kinases; Occludin; Oxygen; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Second Messenger Systems; Thioglycolates; Trans-Activators

1999
Inflammatory mediators induce sequestration of VE-cadherin in cultured human endothelial cells.
    Inflammation, 2000, Volume: 24, Issue:2

    Topics: Antigens, CD; Cadherins; Carbazoles; Cells, Cultured; Cytochalasin D; Cytoskeleton; Edetic Acid; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Histamine; Humans; Hydrogen Peroxide; Indoles; Inflammation Mediators; Membrane Proteins; Protein Binding; Time Factors; Umbilical Veins

2000
Thrombopoietin increases platelet sensitivity to alpha-thrombin via activation of the ERK2-cPLA2 pathway.
    Thrombosis and haemostasis, 2000, Volume: 83, Issue:4

    Topics: Animals; Blood Platelets; Carbazoles; Cattle; Cytoplasmic Granules; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Group IV Phospholipases A2; Humans; Imidazoles; Indoles; Indomethacin; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Platelet Aggregation; Protein Kinase C; Protein Processing, Post-Translational; Pyridines; Serotonin; Serum Albumin, Bovine; Thrombin; Thrombopoietin; Thromboxane A2

2000
Thrombin induces NO release from cultured rat microglia via protein kinase C, mitogen-activated protein kinase, and NF-kappa B.
    The Journal of biological chemistry, 2000, Sep-29, Volume: 275, Issue:39

    Topics: Acetylcysteine; Animals; Carbazoles; Cells, Cultured; Cerebral Cortex; Enzyme Induction; Flavonoids; Imidazoles; Indoles; Maleimides; Microglia; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Protein Kinase C; Proteins; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Receptors, Thrombin; Signal Transduction; Thrombin

2000
Modulation of noradrenaline-induced microvascular constriction by protein kinase inhibitors.
    Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Blood Vessels; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Genistein; In Vitro Techniques; Indoles; Kidney; Male; Maleimides; Mesentery; Norepinephrine; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Staurosporine; Tyrphostins; Vasoconstriction

2001
Signal transduction pathways for activation of extracellular signal-regulated kinase by arachidonic acid in rat neutrophils.
    Journal of leukocyte biology, 2001, Volume: 69, Issue:4

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Androstadienes; Animals; Arachidonic Acid; Arachidonic Acids; Butadienes; Calcium; Carbazoles; Chelating Agents; Chromones; Cyclooxygenase Inhibitors; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Flavonoids; GTP-Binding Protein alpha Subunits, Gi-Go; Heterotrimeric GTP-Binding Proteins; Indoles; Lipoxygenase Inhibitors; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Neutrophils; Nitriles; Pertussis Toxin; Phosphatidylinositol Diacylglycerol-Lyase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Type C Phospholipases; Virulence Factors, Bordetella; Wortmannin

2001
Rapid activation of ERK1/2 mitogen-activated protein kinase by corticosterone in PC12 cells.
    Biochemical and biophysical research communications, 2001, Oct-05, Volume: 287, Issue:4

    Topics: Active Transport, Cell Nucleus; Animals; Anti-Inflammatory Agents; Carbazoles; Corticosterone; Culture Media, Serum-Free; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Immunoblotting; Indoles; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Models, Biological; PC12 Cells; Phosphorylation; Protein Kinase C; Rats

2001
Pharmacological comparison of LTB(4)-induced NADPH oxidase activation in adherent and non-adherent guinea-pig eosinophils.
    British journal of pharmacology, 2001, Volume: 134, Issue:4

    Topics: Androstadienes; Animals; Antibodies; Carbazoles; CD18 Antigens; Cell Adhesion; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Eosinophils; Flavonoids; Guinea Pigs; Imidazoles; Indoles; Integrin beta1; Intracellular Signaling Peptides and Proteins; Leukotriene B4; Macrophage-1 Antigen; Male; Maleimides; Mitogen-Activated Protein Kinases; NADPH Oxidases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Pyrimidines; Rats; src-Family Kinases; Stilbenes; Syk Kinase; Time Factors; Wortmannin

2001
Noradrenaline and alpha-adrenergic signaling induce the hsp70 gene promoter in mollusc immune cells.
    Journal of cell science, 2001, Volume: 114, Issue:Pt 19

    Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbazoles; Chromones; Enzyme Inhibitors; Estrenes; Flavonoids; Gene Expression Regulation; Hemocytes; HSP70 Heat-Shock Proteins; Indoles; Isoproterenol; Isoquinolines; Luciferases; Morpholines; Naphthalenes; Norepinephrine; Ostreidae; Pertussis Toxin; Phenylephrine; Phosphodiesterase Inhibitors; Prazosin; Promoter Regions, Genetic; Propranolol; Pyrrolidinones; Signal Transduction; Sulfonamides; Transfection; Virulence Factors, Bordetella

2001
Activation of phosphatidylinositol 3-kinase is important for erythropoietin-induced erythropoiesis from CD34(+) hematopoietic progenitor cells.
    Experimental hematology, 2002, Volume: 30, Issue:9

    Topics: Adult; Antigens, CD34; Antigens, Differentiation; Butadienes; Carbazoles; Cell Cycle; Cell Differentiation; Cell Division; Cells, Cultured; Chromones; Enzyme Activation; Enzyme Inhibitors; Erythroid Precursor Cells; Erythropoiesis; Erythropoietin; Flavonoids; Glycophorins; Hematopoietic Stem Cells; Humans; Indoles; Isoenzymes; Morpholines; Naphthalenes; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase C-alpha; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Staurosporine; Stem Cell Factor

2002
Staurosporine induces rapid homotypic intercellular adhesion of U937 cells via multiple kinase activation.
    British journal of pharmacology, 2003, Volume: 140, Issue:2

    Topics: Acetophenones; Adenosine Triphosphate; Benzopyrans; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; CD18 Antigens; Cell Aggregation; Cycloheximide; Cytoskeleton; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Genistein; Humans; Imidazoles; Indoles; Integrin beta1; Isoenzymes; Maleimides; Mitogen-Activated Protein Kinases; Naphthalenes; Phosphorylation; Phosphotransferases; Protein Kinase C; Protein-Tyrosine Kinases; Pyridines; Staurosporine; Temperature; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells

2003
Pharmacological analysis of signal transduction pathways required for oxidative burst in chicken heterophils stimulated by a Toll-like receptor 2 agonist.
    International immunopharmacology, 2003, Volume: 3, Issue:12

    Topics: Androstadienes; Animals; Animals, Newborn; Carbazoles; Chickens; Estrenes; Flavonoids; Indoles; Lipopolysaccharides; Male; Membrane Glycoproteins; Neutrophils; Nitriles; Pyrrolidinones; Receptors, Cell Surface; Respiratory Burst; Signal Transduction; Sulfones; Teichoic Acids; Toll-Like Receptor 2; Toll-Like Receptors; Wortmannin

2003
Activation of P2X7 purinoceptor-stimulated TGF-beta 1 mRNA expression involves PKC/MAPK signalling pathway in a rat brain-derived type-2 astrocyte cell line, RBA-2.
    Cellular signalling, 2003, Volume: 15, Issue:12

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Astrocytes; Blotting, Northern; Blotting, Western; Brain; Carbazoles; Cell Line; Dose-Response Relationship, Drug; Flavonoids; Gene Expression; Indoles; Kinetics; Maleimides; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Rats; Receptors, Purinergic P2; Receptors, Purinergic P2X4; Receptors, Purinergic P2X7; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetradecanoylphorbol Acetate; Transforming Growth Factor beta; Transforming Growth Factor beta1

2003
PKA-dependent activation of PKC, p38 MAPK and IKK in macrophage: implication in the induction of inducible nitric oxide synthase and interleukin-6 by dibutyryl cAMP.
    Cellular signalling, 2004, Volume: 16, Issue:5

    Topics: Animals; Bucladesine; Carbazoles; Carrier Proteins; Cell Line; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; I-kappa B Kinase; Indoles; Interleukin-6; Intracellular Signaling Peptides and Proteins; Macrophages; Mice; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Signal Transduction

2004
Identification of proteins differentially expressed during chondrogenesis of mesenchymal cells.
    FEBS letters, 2004, Apr-09, Volume: 563, Issue:1-3

    Topics: Animals; Carbazoles; Cell Differentiation; Cells, Cultured; Chick Embryo; Chondrocytes; Chondrogenesis; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Extracellular Matrix; Flavonoids; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Imidazoles; Indoles; Mesoderm; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Protein Kinases; Proteins; Proteome; Pyridines; Signal Transduction; Time Factors

2004
Transcription factor Ets-1 mediates ischemia- and vascular endothelial growth factor-dependent retinal neovascularization.
    The American journal of pathology, 2004, Volume: 164, Issue:5

    Topics: Adenoviridae; Angiopoietin-2; Animals; Blotting, Northern; Blotting, Western; Butadienes; Carbazoles; Cattle; Cell Division; Disease Models, Animal; DNA; Enzyme Inhibitors; Flavonoids; Genes, Dominant; Humans; Hypoxia; Indoles; Maleimides; Mice; Models, Biological; Neovascularization, Pathologic; Neuropilin-1; Nitriles; Phosphorylation; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-ets; Reperfusion Injury; Retina; RNA, Messenger; Staurosporine; Time Factors; Transcription Factors; Up-Regulation; Vascular Endothelial Growth Factor A

2004
Phorbol ester phorbol-12-myristate-13-acetate promotes anchorage-independent growth and survival of melanomas through MEK-independent activation of ERK1/2.
    Biochemical and biophysical research communications, 2005, Apr-01, Volume: 329, Issue:1

    Topics: Anoikis; Apoptosis; Butadienes; Carbazoles; Cell Adhesion; Cell Culture Techniques; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Progression; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Immunoblotting; Indoles; Melanocytes; Melanoma; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Nitriles; Oligonucleotides, Antisense; Protein Kinase C; Protein Kinase C-alpha; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Transfection

2005
Calcium signaling stimulates translation of HIF-alpha during hypoxia.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2006, Volume: 20, Issue:3

    Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Basic Helix-Loop-Helix Transcription Factors; Benzylamines; Butadienes; Calcium Signaling; Carbazoles; Cell Hypoxia; Cell Line; Cycloheximide; Flavonoids; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indoles; Ionomycin; Isoquinolines; Kidney; Nitriles; PC12 Cells; Polyribosomes; Protein Biosynthesis; Protein Kinase C-alpha; Protein Kinases; Protein Synthesis Inhibitors; Rats; RNA Caps; RNA, Messenger; RNA, Small Interfering; Sirolimus; Sulfonamides; TOR Serine-Threonine Kinases

2006
Activation of the extracellular calcium-sensing receptor initiates insulin secretion from human islets of Langerhans: involvement of protein kinases.
    The Journal of endocrinology, 2006, Volume: 190, Issue:3

    Topics: Aniline Compounds; Antibodies, Monoclonal; Benzylamines; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Communication; Cell Line; Cells, Cultured; Estrenes; Extracellular Fluid; Flavonoids; Glucose; Humans; Immunohistochemistry; Indoles; Insulin; Insulin Secretion; Insulin-Secreting Cells; Mitogen-Activated Protein Kinases; Phenethylamines; Propylamines; Protein Kinase C; Protein Kinases; Pyrrolidinones; Receptors, Calcium-Sensing; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staurosporine; Stimulation, Chemical; Sulfonamides; Type C Phospholipases

2006
Activation of bone morphogenetic protein signaling by a Gemini vitamin D3 analogue is mediated by Ras/protein kinase C alpha.
    Cancer research, 2007, Dec-15, Volume: 67, Issue:24

    Topics: Bone Morphogenetic Proteins; Breast; Breast Neoplasms; Calcitriol; Carbazoles; Cell Line; Cell Line, Tumor; Epithelial Cells; Female; Flavonoids; Humans; Indoles; Kinetics; Protein Kinase C-alpha; ras Proteins; RNA, Neoplasm

2007
Protein kinase Cmu plays an essential role in hypertonicity-induced heat shock protein 70 expression.
    Experimental & molecular medicine, 2008, Dec-31, Volume: 40, Issue:6

    Topics: Animals; Carbazoles; Cell Line; Flavonoids; HSP70 Heat-Shock Proteins; Humans; Indoles; Isoquinolines; Maleimides; MAP Kinase Signaling System; Mice; NFATC Transcription Factors; Phosphorylation; Promoter Regions, Genetic; Protein Kinase C; Protein Transport; Saline Solution, Hypertonic; Signal Transduction; Sulfonamides

2008
A(1) adenosine receptor-mediated PKC and p42/p44 MAPK signaling in mouse coronary artery smooth muscle cells.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:3

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Carbazoles; Cell Membrane; Cells, Cultured; Coronary Vessels; Cytosol; Enzyme Inhibitors; Female; Flavonoids; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Phospholipase C beta; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-alpha; Receptor, Adenosine A1

2009
Nav1.7-Ca2+ influx-induced increased phosphorylations of extracellular signal-regulated kinase (ERK) and p38 attenuate tau phosphorylation via glycogen synthase kinase-3beta: priming of Nav1.7 gating by ERK and p38.
    European journal of pharmacology, 2010, Aug-25, Volume: 640, Issue:1-3

    Topics: Animals; Calcium; Carbazoles; Cattle; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Growth Cones; Humans; Imidazoles; Ion Channel Gating; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Nicotine; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase C-alpha; Pyridines; Receptors, Nicotinic; Sodium Channels; tau Proteins; Tetrodotoxin; Time Factors; Veratridine

2010
C3b-induced eosinophil degranulation involves PI3-kinases and is inhibited by protein kinase C activity.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2011, Volume: 119, Issue:2

    Topics: Carbazoles; Cell Degranulation; Complement C3b; Eosinophils; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Staurosporine

2011
Role of PKC-ERK signaling in tamoxifen-induced apoptosis and tamoxifen resistance in human breast cancer cells.
    Oncology reports, 2012, Volume: 27, Issue:6

    Topics: Acetophenones; Antineoplastic Agents, Hormonal; Apoptosis; Benzopyrans; Breast Neoplasms; Carbazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Humans; Protein Kinase C-alpha; Protein Kinase C-delta; Receptors, Estrogen; Signal Transduction; Tamoxifen

2012
Potential role of sodium-proton exchangers in the low concentration arsenic trioxide-increased intracellular pH and cell proliferation.
    PloS one, 2012, Volume: 7, Issue:12

    Topics: Amiloride; Analysis of Variance; Animals; Arsenic Trioxide; Arsenicals; Blotting, Western; Carbazoles; Cell Count; Cell Fractionation; Cell Proliferation; Dogs; Flavonoids; Fluorometry; Hydrogen-Ion Concentration; Imidazoles; Macrolides; Madin Darby Canine Kidney Cells; Oxides; Sodium-Hydrogen Exchangers

2012
Adenosine A1 receptors link to smooth muscle contraction via CYP4a, protein kinase C-α, and ERK1/2.
    Journal of cardiovascular pharmacology, 2013, Volume: 62, Issue:1

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Animals; Blotting, Western; Carbazoles; Cytochrome P-450 CYP4A; Enzyme Inhibitors; Female; Flavonoids; Hydroxyeicosatetraenoic Acids; Isometric Contraction; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle, Smooth, Vascular; Protein Kinase C-alpha; Receptor, Adenosine A1

2013
Mechanism of tissue factor production by monocytes stimulated with neutrophil elastase.
    Blood cells, molecules & diseases, 2015, Volume: 54, Issue:2

    Topics: Calcium Channel Blockers; Carbazoles; Enzyme Inhibitors; Estrenes; Flavonoids; Gallic Acid; Gene Expression Regulation; Humans; Imidazoles; Indoles; Leukocyte Elastase; Maleimides; Monocytes; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Pyrrolidinones; RNA, Messenger; Signal Transduction; Thromboplastin; Type C Phospholipases

2015
Signaling Pathway for Endothelin-1- and Phenylephrine-Induced cAMP Response Element Binding Protein Activation in Rat Ventricular Myocytes: Role of Inositol 1,4,5-Trisphosphate Receptors and CaMKII.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 41, Issue:1

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Carbazoles; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Endothelin-1; Flavonoids; Inositol 1,4,5-Trisphosphate Receptors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Phenylephrine; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Signal Transduction; Type C Phospholipases

2017