pd 98059 has been researched along with fulvestrant in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 19 (79.17) | 29.6817 |
| 2010's | 5 (20.83) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H | 1 |
| Frail, DE; Guan, X; Sétáló, G; Singh, M; Toran-Allerand, CD | 1 |
| Huper, G; Iglehart, JD; Lobenhofer, EK; Marks, JR | 1 |
| Akaike, A; Honda, K; Kihara, T; Nakamizo, T; Sawada, H; Shimohama, S; Urushitani, M | 1 |
| Bruce-Keller, AJ; Camondola, S; Huang, FF; Keeling, JL; Keller, JN; Mattson, MP | 1 |
| Eischeid, A; Jeng, MH; Santen, RJ; Wang, JP; Yue, W | 1 |
| de Jager, T; Imam, A; Muck, J; Müller-Botz, S; Neyses, L; Pelzer, T | 1 |
| Adachi, K; Hayakawa, J; Hisamoto, K; Kanda, Y; Mabuchi, S; Miyamoto, Y; Murata, Y; Nishio, Y; Ohmichi, M; Takahashi, K; Taniguchi, N; Tasaka, K | 1 |
| Dorsa, DM; Mize, AL; Shapiro, RA | 1 |
| Bjeldanes, LF; Firestone, GL; Leong, H; Riby, JE | 1 |
| Bellesini, LS; Beloti, MM; de Oliveira, PT; Rosa, AL | 1 |
| Han, SY; Hong, JT; Kim, DJ; Kim, TM; Kim, TS; Lee, JW; Lee, YK; Lee, YM; Nam, SY; Seong, MJ; Yun, YW | 1 |
| Cheng, J; Shapiro, DJ; Yu, DV; Zhou, JH | 1 |
| Gooderham, NJ; Lauber, SN | 1 |
| Arshad, F; Braun, AP; Braun, JE; Sheng, JZ | 1 |
| Chung, KY; Dayton, WR; Hathaway, MR; Johnson, BJ; Kamanga-Sollo, E; White, ME | 1 |
| Akishita, M; Eto, M; Kozaki, K; Okabe, T; Ouchi, Y; Yu, J | 1 |
| Kabil, A; Kortenkamp, A; Silva, E | 1 |
| Aleskandarany, M; Ball, G; Douglas Macmillan, R; Ellis, IO; Gee, JM; Green, AR; Habashy, HO; Nicholson, RI; Paish, EC; Powe, DG; Rakha, EA; Staka, CM | 1 |
| Hatae, J; Honda, A; Inoue, R; Lin, H; Takami, N | 1 |
| Du, X; Lee, C; Mei, M; Park, I; Shi, J; Wang, L; Zhang, J; Zhang, Z; Zhu, Y | 1 |
| Choi, EM; Lee, YS | 1 |
| Hojo, Y; Kawato, S; Kimoto, T; Ogiue-Ikeda, M; Shimohigashi, Y; Tanabe, N; Yoshino, H | 1 |
| Gao, R; Jiang, L; Liu, J; Liu, Y; Qian, W; Wang, J; Xiao, H; Zhou, J; Zhu, J | 1 |
24 other study(ies) available for pd 98059 and fulvestrant
| Article | Year |
|---|---|
Identifying off-target effects and hidden phenotypes of drugs in human cells.
Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship | 2006 |
Estrogen-induced activation of the mitogen-activated protein kinase cascade in the cerebral cortex of estrogen receptor-alpha knock-out mice.
Topics: Animals; Brain Chemistry; Cells, Cultured; Cerebral Cortex; Enzyme Inhibitors; Escherichia coli Proteins; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Flavonoids; Fulvestrant; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Genotype; Male; MAP Kinase Signaling System; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Receptors, Estrogen | 2000 |
Inhibition of mitogen-activated protein kinase and phosphatidylinositol 3-kinase activity in MCF-7 cells prevents estrogen-induced mitogenesis.
Topics: Adenocarcinoma; Androstadienes; Breast Neoplasms; Butadienes; Chromones; Culture Media, Serum-Free; Cyclic AMP-Dependent Protein Kinases; Cyclin D1; Depression, Chemical; DNA Replication; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Receptor Modulators; Estrogens; Female; Flavonoids; Fulvestrant; Humans; Isoquinolines; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitosis; Morpholines; Neoplasm Proteins; Neoplasms, Hormone-Dependent; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Retinoblastoma Protein; Sulfonamides; Wortmannin | 2000 |
Phosphatidylinositol 3-kinase mediates neuroprotection by estrogen in cultured cortical neurons.
Topics: Animals; Blotting, Western; Cell Survival; Cells, Cultured; Cerebral Cortex; Chromones; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Excitatory Amino Acid Antagonists; Flavonoids; Fulvestrant; Glutamic Acid; Morpholines; Neurons; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley | 2000 |
Antiinflammatory effects of estrogen on microglial activation.
Topics: Animals; Anti-Inflammatory Agents; Cells, Cultured; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; Microglia; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phagocytosis; Rats; Receptors, Estrogen; Superoxides | 2000 |
Role of MAP kinase in the enhanced cell proliferation of long term estrogen deprived human breast cancer cells.
Topics: Breast Neoplasms; Cell Division; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Female; Flavonoids; Fulvestrant; Humans; MAP Kinase Signaling System; Neoplasms, Hormone-Dependent; Receptors, Estrogen; Thymidine; Transcription, Genetic; Tumor Cells, Cultured; Up-Regulation | 2000 |
Mechanisms of estrogen receptor action in the myocardium. Rapid gene activation via the ERK1/2 pathway and serum response elements.
Topics: Animals; Animals, Newborn; Blotting, Northern; Cell Nucleus; Cells, Cultured; DNA-Binding Proteins; Early Growth Response Protein 1; Estradiol; Flavonoids; Fulvestrant; Immediate-Early Proteins; Immunoblotting; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Myocardium; Nuclear Proteins; Plasmids; Promoter Regions, Genetic; Rats; Rats, Wistar; Receptors, Estrogen; RNA, Messenger; Serum Response Factor; Time Factors; Transcription Factors; Transfection | 2001 |
Induction of endothelial nitric-oxide synthase phosphorylation by the raloxifene analog LY117018 is differentially mediated by Akt and extracellular signal-regulated protein kinase in vascular endothelial cells.
Topics: Animals; Cell Line, Transformed; Cells, Cultured; CHO Cells; Cricetinae; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Flavonoids; Fulvestrant; Humans; Lung; Mitogen-Activated Protein Kinases; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrrolidines; Raloxifene Hydrochloride; Rats; Receptors, Estradiol; Thiophenes; Time Factors; Umbilical Veins | 2001 |
Estrogen receptor-mediated neuroprotection from oxidative stress requires activation of the mitogen-activated protein kinase pathway.
Topics: Animals; Cell Line; Cell Survival; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Flavonoids; Fulvestrant; Glutamic Acid; Hippocampus; Humans; Mitogen-Activated Protein Kinases; Mutation; Neuroprotective Agents; Oxidative Stress; Rats; Receptors, Estrogen; Transfection | 2003 |
Potent ligand-independent estrogen receptor activation by 3,3'-diindolylmethane is mediated by cross talk between the protein kinase A and mitogen-activated protein kinase signaling pathways.
Topics: Adenocarcinoma; Anticarcinogenic Agents; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Endometrial Neoplasms; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Female; Flavonoids; Fulvestrant; Humans; Indoles; Isoquinolines; Ligands; MAP Kinase Signaling System; Phosphoprotein Phosphatases; Phosphorylation; Point Mutation; Sulfonamides; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured | 2004 |
Participation of estrogen receptors in the enhancement of osteoblast differentiation by TAK-778.
Topics: Alkaline Phosphatase; Benzothiepins; Cell Differentiation; Cell Proliferation; Cells, Cultured; Collagen; Drug Combinations; Estradiol; Flavonoids; Fulvestrant; Humans; Microscopy, Fluorescence; Osteoblasts; Osteogenesis; Receptors, Estrogen | 2006 |
Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen.
Topics: Animals; Apoptosis; Benzhydryl Compounds; Blotting, Western; Cell Differentiation; Cell Survival; Estradiol; Estrogens, Non-Steroidal; Flavonoids; Fulvestrant; Neurons; NF-kappa B; PC12 Cells; Phenols; Rats; Receptors, Estrogen; Tamoxifen | 2007 |
Delayed and persistent ERK1/2 activation is required for 4-hydroxytamoxifen-induced cell death.
Topics: Caspase 3; Caspase 9; Cell Death; Enzyme Activation; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; HeLa Cells; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptors, Estrogen; Tamoxifen; Time Factors | 2007 |
The cooked meat derived genotoxic carcinogen 2-amino-3-methylimidazo[4,5-b]pyridine has potent hormone-like activity: mechanistic support for a role in breast cancer.
Topics: Animals; Breast Neoplasms; Carcinogens; Cell Growth Processes; Estradiol; Flavonoids; Fulvestrant; Imidazoles; Pituitary Gland; Prolactin; Rats | 2007 |
Estrogen and the Ca2+-mobilizing agonist ATP evoke acute NO synthesis via distinct pathways in an individual human vascular endothelium-derived cell.
Topics: Adenosine Triphosphate; Apamin; Calcium Signaling; Cell Line; Charybdotoxin; Chelating Agents; Chromones; Cytophotometry; Egtazic Acid; Endothelial Cells; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; Humans; Membrane Potentials; Mitogen-Activated Protein Kinases; Morpholines; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Patch-Clamp Techniques; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Protein Kinase Inhibitors; Time Factors; Up-Regulation | 2008 |
Roles of IGF-I and the estrogen, androgen and IGF-I receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells.
Topics: Anabolic Agents; Androstadienes; Animals; Cattle; Cell Proliferation; Cells, Cultured; Culture Media; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; Gene Expression; Insulin-Like Growth Factor I; Mitogen-Activated Protein Kinase Kinases; Receptor, IGF Type 1; Receptors, Androgen; Receptors, Estrogen; RNA, Messenger; Satellite Cells, Skeletal Muscle; Trenbolone Acetate; Wortmannin | 2008 |
Raloxifene analogue LY117018 suppresses oxidative stress-induced endothelial cell apoptosis through activation of ERK1/2 signaling pathway.
Topics: Animals; Apoptosis; Cattle; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Activation; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; Hydrogen Peroxide; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Oxidants; Oxidative Stress; Phosphorylation; Protein Kinase Inhibitors; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Thiophenes | 2008 |
Estrogens and genomic instability in human breast cancer cells--involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals.
Topics: Benzhydryl Compounds; Benzo(a)pyrene; Breast Neoplasms; Cell Line, Tumor; Estradiol; Estrogens; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Fulvestrant; Genomic Instability; Humans; Kinetochores; Micronuclei, Chromosome-Defective; Phenols; raf Kinases; Receptors, Estrogen; Signal Transduction; src-Family Kinases; Tamoxifen | 2008 |
Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen.
Topics: Adult; Antigens, CD; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Carcinoma; Cell Line, Tumor; Cell Proliferation; Chromones; Drug Resistance, Neoplasm; Estradiol; Female; Flavonoids; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Middle Aged; Mitogen-Activated Protein Kinases; Morpholines; Neoplasm Invasiveness; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Predictive Value of Tests; Proportional Hazards Models; Protein Kinase Inhibitors; Receptors, Estrogen; Receptors, Transferrin; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Risk Assessment; RNA, Messenger; Tamoxifen; Time Factors; Tissue Array Analysis; Transferrin; Treatment Outcome | 2010 |
17beta-Estradiol-induced enhancement of estrogen receptor biosynthesis via MAPK pathway in mouse skeletal muscle myoblasts.
Topics: Animals; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogens; Flavonoids; Fulvestrant; Imidazoles; Mice; Mitogen-Activated Protein Kinase Kinases; Models, Animal; Muscle, Skeletal; Myoblasts, Skeletal; Pyridines; Receptors, Estrogen; Signal Transduction; Tamoxifen | 2009 |
Both nongenomic and genomic effects are involved in estradiol's enhancing the phenotype of smooth muscle cells in cultured prostate stromal cells.
Topics: Antibodies, Neutralizing; Cell Differentiation; Cells, Cultured; Drug Synergism; Estradiol; Estrogen Antagonists; Flavonoids; Fulvestrant; Gene Expression Regulation; Genome, Human; Humans; Male; MAP Kinase Signaling System; Myocytes, Smooth Muscle; Phenotype; Prostate; Serum Albumin, Bovine; Stromal Cells; Transforming Growth Factor beta1; Up-Regulation | 2010 |
Effect of pollen from Typha angustata on hydrogen peroxide induced toxicity in osteoblastic MC3T3-E1 cells.
Topics: 3T3 Cells; Acetophenones; Alkaline Phosphatase; Animals; Benzopyrans; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Culture Techniques; Cell Differentiation; Collagen; Enzyme Activation; Estradiol; Estrogen Antagonists; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Fulvestrant; Hydrogen Peroxide; Lipid Peroxidation; Malondialdehyde; Mice; Osteoblasts; Osteocalcin; Oxidants; Oxidative Stress; Plant Extracts; Pollen; Protein Carbonylation; Protein Kinase C; RANK Ligand; Typhaceae | 2012 |
Nanomolar dose of bisphenol A rapidly modulates spinogenesis in adult hippocampal neurons.
Topics: Animals; Benzhydryl Compounds; Dendritic Spines; Dizocilpine Maleate; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Flavonoids; Fulvestrant; Hippocampus; Humans; Male; Mitogen-Activated Protein Kinases; Neurons; Phenols; Rats; Rats, Wistar; Receptors, Estrogen; Receptors, N-Methyl-D-Aspartate; Tamoxifen | 2012 |
MAPK and NF-κB pathways are involved in bisphenol A-induced TNF-α and IL-6 production in BV2 microglial cells.
Topics: Animals; Anthracenes; Anti-Inflammatory Agents; Benzhydryl Compounds; Cell Line; Endocrine Disruptors; Enzyme Activation; Estradiol; Estrogen Receptor Antagonists; Estrogen Receptor Modulators; Estrogens; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Fulvestrant; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Microglia; Neurodegenerative Diseases; NF-kappa B; Phenols; Tumor Necrosis Factor-alpha | 2015 |