pd 98059 has been researched along with cyclosporine in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (14.81) | 18.2507 |
| 2000's | 16 (59.26) | 29.6817 |
| 2010's | 7 (25.93) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Alemany, S; Ballester, A; Tobeña, R; Velasco, A | 1 |
| Patriotis, C; Tsatsanis, C; Tsichlis, PN | 1 |
| Chayama, K; Gelfand, EW; Hamelmann, E; Ishizuka, T; Johnson, GL; Keller, GM; Takeda, K; Terada, N | 1 |
| Darnell, BF; Grammer, AC; Heaney, J; Lipsky, PE; McFarland, RD | 1 |
| Alam, T; Cho, CS; Hamawy, MM; Knechtle, SJ; Manthei, ER; Peters, D; Tsuchida, M | 1 |
| Beale, G; Cross, J; England, K; Rumsby, M; Warner, M; Watson, J | 1 |
| Fornoni, A; Foschi, A; Li, H; Striker, GE; Striker, LJ | 1 |
| Laan, M; Lindén, A; Lötvall, J; Prause, O | 1 |
| Feldman, G; Kiely, B; Ryan, MP | 1 |
| DeGregori, J; DeRyckere, D; Mann, DL | 1 |
| Coleman, JW; Davis, BJ; Dearman, RJ; Flanagan, BF; Kimber, I; Koranteng, RD; Swindle, EJ | 1 |
| Liot, G; Lobner, D | 1 |
| Bíró, T; Csortos, C; Czifra, G; Gergely, P; Juhász, T; Matta, C; Módis, L; Szíjgyártó, Z; Szucs, K; Zákány, R | 1 |
| Adragna, NC; Lauf, PK; Zhang, J | 1 |
| Camerini, D; Choudhary, SK; Planelles, V; Powell, DM; Walker, RM; Walsh, C | 1 |
| Adamczyk, J; Fischer, I; Gabryel, B; Malecki, A; Pudelko, A | 1 |
| Diao, H; Du, C; Guan, Q; Jevnikar, AM; Lian, D; Wang, S; Zhong, R | 1 |
| Kobayashi, D; Nakahata, N; Ohkubo, S | 1 |
| Cook, IH; Critchley, HO; Evans, J; Jabbour, HN; Maldonado-Pérez, D; Sales, KJ | 1 |
| Bao, SL; Kuang, ZJ; Li, YG; Mao, YY; Tang, CS; Wei, RH; Wu, LB; Zhang, YG | 1 |
| Chang, YC; Huang, FM; Kuan, YH; Lee, SS; Tsai, CH | 1 |
| Kotsimbos, TC; Levvey, BJ; Meehan, AC; Mifsud, NA; Nguyen, TH; Snell, GI; Westall, GP | 1 |
| Gergely, P; Hajdú, T; Juhász, T; Katona, É; Kókai, E; Rácz, K; Somogyi, CS; Szász, C; Zákány, R | 1 |
| Godbole, S; Paranjape, R; Pawar, J; Shete, A; Suryawanshi, P; Thakar, M | 1 |
| Jiang, XJ; Sun, WB; Zhang, DX; Zhang, LM; Zhao, XC | 1 |
1 trial(s) available for pd 98059 and cyclosporine
| Article | Year |
|---|---|
Impact of commonly used transplant immunosuppressive drugs on human NK cell function is dependent upon stimulation condition.
Topics: Acetophenones; Adult; Benzopyrans; Cells, Cultured; Chromones; Cyclosporine; Female; Flavonoids; Humans; Immunosuppressive Agents; Interferon-gamma; Killer Cells, Natural; Lung Transplantation; Lysosomal-Associated Membrane Protein 1; Male; Morpholines; Mycophenolic Acid; Prednisolone | 2013 |
26 other study(ies) available for pd 98059 and cyclosporine
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Cot kinase activates tumor necrosis factor-alpha gene expression in a cyclosporin A-resistant manner.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Antibodies; Calcimycin; CD28 Antigens; CD3 Complex; Cyclosporine; Dexamethasone; Flavonoids; Gene Expression Regulation, Neoplastic; Genes, Reporter; Humans; Jurkat Cells; MAP Kinase Kinase Kinases; Phorbol 12,13-Dibutyrate; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Messenger; Transcription Factor AP-1; Transcriptional Activation; Transfection; Tumor Necrosis Factor-alpha | 1998 |
Tpl-2 induces IL-2 expression in T-cell lines by triggering multiple signaling pathways that activate NFAT and NF-kappaB.
Topics: Animals; bcl-X Protein; Calcineurin; Calcium-Calmodulin-Dependent Protein Kinases; COS Cells; Cyclosporine; DNA-Binding Proteins; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Humans; Immunosuppressive Agents; Interleukin-2; Jurkat Cells; Lymphoma, T-Cell; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Kinase Kinases; Mice; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Neoplasm Proteins; NF-kappa B; NFATC Transcription Factors; Nuclear Proteins; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Signal Transduction; T-Lymphocytes; Transcription Factors; Transcription, Genetic; Tumor Cells, Cultured | 1998 |
Mitogen-activated protein kinase activation through Fc epsilon receptor I and stem cell factor receptor is differentially regulated by phosphatidylinositol 3-kinase and calcineurin in mouse bone marrow-derived mast cells.
Topics: Amino Acid Sequence; Androstadienes; Animals; Bone Marrow Cells; Calcineurin; Calcium-Calmodulin-Dependent Protein Kinases; Cyclosporine; Enzyme Activation; Female; Flavonoids; Interleukin-4; JNK Mitogen-Activated Protein Kinases; Mast Cells; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Molecular Sequence Data; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-kit; Receptor Aggregation; Receptors, IgE; Serotonin; Serotonin Antagonists; Tumor Necrosis Factor-alpha; Wortmannin | 1999 |
Expression, regulation, and function of B cell-expressed CD154 in germinal centers.
Topics: Acetylcysteine; B-Lymphocyte Subsets; CD40 Antigens; CD40 Ligand; Cell Communication; Cell Count; Cell Separation; Cells, Cultured; Cyclosporine; Flavonoids; Germinal Center; Humans; Immunologic Memory; Immunophenotyping; Ligands; Lymphocyte Activation; Membrane Glycoproteins; Palatine Tonsil; Protein Synthesis Inhibitors; Receptors, Antigen, B-Cell; Up-Regulation | 1999 |
Potentiation of CD3-induced expression of the linker for activation of T cells (LAT) by the calcineurin inhibitors cyclosporin A and FK506.
Topics: Adaptor Proteins, Signal Transducing; Calcimycin; Calcineurin Inhibitors; Carrier Proteins; CD28 Antigens; CD3 Complex; Cells, Cultured; Cyclosporine; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation; Humans; Indoles; Jurkat Cells; Lymphocyte Activation; Membrane Proteins; Phosphoproteins; Protein Kinase C; Receptor-CD3 Complex, Antigen, T-Cell; T-Lymphocytes; Tacrolimus; Transcription, Genetic | 2000 |
Signalling pathways regulating the dephosphorylation of Ser729 in the hydrophobic domain of protein kinase Cepsilon upon cell passage.
Topics: 3T3 Cells; Alkaloids; Animals; Anti-Bacterial Agents; Benzophenanthridines; Blotting, Western; Calcineurin; Cell Adhesion; Cell Line; Culture Media; Cyclosporine; Down-Regulation; Enzyme Inhibitors; Flavonoids; Indoles; Isoenzymes; MAP Kinase Signaling System; Marine Toxins; Methionine; Mice; Models, Biological; Okadaic Acid; Oxazoles; Phenanthridines; Phosphoprotein Phosphatases; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Kinase C-epsilon; Protein Structure, Tertiary; Serine; Signal Transduction; Sirolimus; Tacrolimus; Transfection | 2001 |
Hepatocyte growth factor, but not insulin-like growth factor I, protects podocytes against cyclosporin A-induced apoptosis.
Topics: Animals; Apoptosis; bcl-X Protein; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fas Ligand Protein; fas Receptor; Female; Flavonoids; Hepatocyte Growth Factor; Insulin-Like Growth Factor I; Kidney Glomerulus; MAP Kinase Kinase 1; Membrane Glycoproteins; Mice; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Time Factors | 2001 |
Pharmacological modulation of interleukin-17-induced GCP-2-, GRO-alpha- and interleukin-8 release in human bronchial epithelial cells.
Topics: Adrenergic beta-Agonists; Albuterol; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bronchi; Calcineurin Inhibitors; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line, Transformed; Chemokine CXCL1; Chemokine CXCL6; Chemokines; Chemokines, CXC; Chemotactic Factors; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Humans; Hydrocortisone; Imidazoles; Intercellular Signaling Peptides and Proteins; Interleukin-17; Interleukin-8; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Receptors, Adrenergic, beta; Receptors, Glucocorticoid | 2003 |
Modulation of renal epithelial barrier function by mitogen-activated protein kinases (MAPKs): mechanism of cyclosporine A-induced increase in transepithelial resistance.
Topics: Animals; Biological Transport; Cell Line; Cyclosporine; Electric Impedance; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Imidazoles; Immunosuppressive Agents; Kidney; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines | 2003 |
Characterization of transcriptional regulation during negative selection in vivo.
Topics: Amino Acid Sequence; Animals; Apoptosis; Cell Differentiation; Conserved Sequence; Cyclosporine; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Gene Expression Profiling; Injections, Intraperitoneal; Mice; Mice, Knockout; Mice, Transgenic; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Ovalbumin; Peptide Fragments; Receptors, Antigen, T-Cell; RNA; Signal Transduction; T-Lymphocyte Subsets; Thymus Gland; Transcription, Genetic | 2003 |
Differential regulation of mast cell cytokines by both dexamethasone and the p38 mitogen-activated protein kinase (MAPK) inhibitor SB203580.
Topics: Cells, Cultured; Cyclosporine; Cytokines; Dexamethasone; Enzyme Inhibitors; Flavonoids; Glucocorticoids; Humans; Imidazoles; Interleukin-4; Interleukin-6; Mast Cells; Phosphorylation; Pyridines; RNA, Messenger; Serotonin; Tumor Necrosis Factor-alpha | 2004 |
Role of MAPK/ERK in neurotrophin-4 potentiation of necrotic neuronal death.
Topics: Animals; Butadienes; Cell Death; Cells, Cultured; Cyclosporine; Enzyme Activation; Flavonoids; Immunosuppressive Agents; L-Lactate Dehydrogenase; Mice; Mitogen-Activated Protein Kinases; Necrosis; Nerve Growth Factors; Neurons; Nitriles; Phosphorylation; Tetrazolium Salts; Thiazoles | 2004 |
Hydrogen peroxide inhibits formation of cartilage in chicken micromass cultures and decreases the activity of calcineurin: implication of ERK1/2 and Sox9 pathways.
Topics: Animals; Calcineurin; Calcineurin Inhibitors; Cartilage; Chick Embryo; Chondrocytes; Cyclosporine; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Developmental; High Mobility Group Proteins; Hydrogen Peroxide; Limb Buds; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Organ Culture Techniques; Reverse Transcriptase Polymerase Chain Reaction; SOX9 Transcription Factor; Transcription Factors | 2005 |
PDGF activates K-Cl cotransport through phosphoinositide 3-kinase and protein phosphatase-1 in primary cultures of vascular smooth muscle cells.
Topics: Androstadienes; Animals; Becaplermin; Cells, Cultured; Chlorides; Chromones; Cyclosporine; Flavonoids; K Cl- Cotransporters; Marine Toxins; Mitogen-Activated Protein Kinase Kinases; Morpholines; Muscle, Smooth, Vascular; Okadaic Acid; Oxazoles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoprotein Phosphatases; Platelet-Derived Growth Factor; Potassium; Protein Phosphatase 1; Proto-Oncogene Proteins c-sis; Rats; Rats, Sprague-Dawley; Symporters; Vanadates; Wortmannin | 2005 |
CXCR4 tropic human immunodeficiency virus type 1 induces an apoptotic cascade in immature infected thymocytes that resembles thymocyte negative selection.
Topics: Apoptosis; Caspases; CD4 Antigens; CD8 Antigens; Cell Differentiation; Cyclosporine; Flavonoids; Gene Expression; HIV Infections; HIV-1; Humans; In Vitro Techniques; Protein Biosynthesis; Receptors, CXCR4; T-Lymphocytes; Virus Replication | 2006 |
Calcineurin and Erk1/2-signaling pathways are involved in the antiapoptotic effect of cyclosporin A on astrocytes exposed to simulated ischemia in vitro.
Topics: Androstadienes; Animals; Animals, Newborn; Apoptosis; Astrocytes; bcl-X Protein; Blotting, Western; Calcineurin; Calcineurin Inhibitors; Caspase 3; Caspase Inhibitors; Cell Hypoxia; Cyclosporine; Dose-Response Relationship, Drug; Flavonoids; Immunoblotting; Immunosuppressive Agents; Mitogen-Activated Protein Kinase 3; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Wistar; Signal Transduction; Transcription Factor RelA; Wortmannin | 2006 |
Prolongation of cardiac allograft survival by inhibition of ERK1/2 signaling in a mouse model.
Topics: Animals; Cyclosporine; Drug Interactions; Drug Therapy, Combination; Flavonoids; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppression Therapy; Interferon-gamma; Interleukin-4; Lymphocyte Activation; Male; Mice; Mice, Inbred Strains; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Protein Kinase Inhibitors; Signal Transduction; T-Lymphocytes; Th2 Cells | 2007 |
Cooperation of calcineurin and ERK for UTP-induced IL-6 production in HaCaT keratinocytes.
Topics: Calcineurin; Cell Line; Cyclosporine; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression; Humans; Immunosuppressive Agents; Interleukin-6; Keratinocytes; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tacrolimus; Uridine Triphosphate | 2007 |
Prokineticin-1 (PROK1) modulates interleukin (IL)-11 expression via prokineticin receptor 1 (PROKR1) and the calcineurin/NFAT signalling pathway.
Topics: Calcineurin; Calcineurin Inhibitors; Cell Line, Tumor; Cyclosporine; Decidua; Egtazic Acid; Endometrium; Enzyme-Linked Immunosorbent Assay; Female; Flavonoids; Gene Expression Regulation; Humans; Immunohistochemistry; Interleukin-11; NFATC Transcription Factors; Peptides, Cyclic; Pregnancy; Pregnancy Trimester, First; Receptors, G-Protein-Coupled; Vascular Endothelial Growth Factor, Endocrine-Gland-Derived | 2010 |
Osteopontin is involved in urotensin II-induced migration of rat aortic adventitial fibroblasts.
Topics: Amides; Animals; Calcium Channels; Cell Movement; Culture Media; Cyclosporine; Dose-Response Relationship, Drug; Fibroblasts; Flavonoids; Gene Expression Regulation; Male; Nicardipine; Oligonucleotides; Oligonucleotides, Antisense; Osteopontin; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Time Factors; Urotensins | 2011 |
The upregulation of transglutaminase-2 by cyclosporin a in human gingival fibroblasts is augmented by oxidative stress.
Topics: Acetylcysteine; Adult; Antioxidants; Catechin; Cell Culture Techniques; Cells, Cultured; Chromones; Curcumin; Cyclosporine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Female; Fibroblasts; Flavonoids; Free Radical Scavengers; Gingiva; GTP-Binding Proteins; Humans; Imidazoles; Immunosuppressive Agents; Male; Morpholines; Oxidative Stress; Phosphoinositide-3 Kinase Inhibitors; Protease Inhibitors; Protein Glutamine gamma Glutamyltransferase 2; Pyridines; Reactive Oxygen Species; Transglutaminases; Up-Regulation | 2013 |
PP2B and ERK1/2 regulate hyaluronan synthesis of HT168 and WM35 human melanoma cell lines.
Topics: Calcineurin; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclosporine; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; Humans; Hyaluronan Receptors; Hyaluronan Synthases; Hyaluronic Acid; MAP Kinase Signaling System; Melanoma; Phosphoproteins; Phosphorylation; Protein Phosphatase 2 | 2016 |
HIV-infected CD4+ T Cells Use T-bet-dependent Pathway for Production of IL-10 Upon Antigen Recognition.
Topics: Adult; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Cells, Cultured; Cyclosporine; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Forkhead Transcription Factors; HIV Core Protein p24; HIV Infections; Humans; Interferon-gamma; Interleukin-10; Lymphocyte Activation; Male; Middle Aged; Quinolones; T-Box Domain Proteins; Young Adult | 2016 |
Sevoflurane pre-conditioning increases phosphorylation of Erk1/2 and HO-1 expression via inhibition of mPTP in primary rat cortical neurons exposed to OGD/R.
Topics: Animals; Apoptosis; Atractyloside; Cell Hypoxia; Cells, Cultured; Cerebral Cortex; Cyclosporine; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Flavonoids; Glucose; Heme Oxygenase (Decyclizing); MAP Kinase Signaling System; Methyl Ethers; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Neuroprotective Agents; Phosphorylation; Rats, Sprague-Dawley; Sevoflurane | 2017 |