pd 98059 has been researched along with bradykinin in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (29.17) | 18.2507 |
| 2000's | 16 (66.67) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gould, GW; Plevin, R; Robinson, CJ; Scott, PH | 1 |
| Rozengurt, E; Seufferlein, T | 1 |
| Pyne, NJ; Pyne, S; Tolan, D | 1 |
| Kosugi, Y; Kudo, I; Murakami, M; Naraba, H; Oh-ishi, S; Ueno, A; Yoshimura, M | 1 |
| Hamada, Y; Nakahata, N; Nakatani, K; Ohizumi, Y; Tsurufuji, S | 1 |
| Marsh, JD; Ritchie, RH; Schiebinger, RJ | 1 |
| Fukuda, M; Miki, H; Nishida, E; Takenawa, T | 1 |
| Bernier, SG; Haldar, S; Michel, T | 1 |
| Chien, CS; Chiu, CT; Hsiao, LD; Lin, CH; Luo, SF; Wang, CC; Yang, CM | 1 |
| Arai, N; Araya, J; Fujita, T; Hayashi, R; Kashii, T; Kobayashi, M; Maruyama, M; Matsui, S; Sassa, K; Sugiyama, E; Yamashita, N; Yoshida, Y | 1 |
| Christopher, JT; Douillet, CD; Jaffa, AA; Mayfield, RK; Trojanowska, ME; Velarde, V | 1 |
| Drube, S; Liebmann, C | 1 |
| Chien, CS; Chiu, CT; Hsiao, LD; Hsu, YM; Liang, KY; Luo, SF; Wang, CC; Yang, CM | 1 |
| Christopher, J; Jaffa, AA; Velarde, V | 1 |
| Gibraeil, HD; Mayer, B; Schmidt, K | 1 |
| Cohen, MV; Cui, L; Downey, JM; Krieg, T; Yang, XM | 1 |
| Hirano, K; Kanaide, H; Maeda, Y; Nishimura, J; Sasaki, T | 1 |
| Hsieh, HL; Jou, MJ; Yang, CM; Yen, MH | 1 |
| Adner, M; Bryborn, M; Cardell, LO | 1 |
| Hsieh, HL; Hwang, TL; Parker, P; Wu, CY; Yang, CM; Yen, MH | 1 |
| Corvol, P; Hus-Citharel, A; Iturrioz, X; Llorens-Cortes, C; Marchetti, J | 1 |
| Greco, S; Marsigliante, S; Storelli, C | 1 |
| Cui, M; Dong, Q; Liu, L; Luo, BY; Ren, HM; Shao, Y; Tang, M; Xiao, BG; Zhou, HG | 1 |
| Endoh, T; Sueishi, K; Tazaki, M; Uchida, Y | 1 |
24 other study(ies) available for pd 98059 and bradykinin
| Article | Year |
|---|---|
Efficacy of agonist-stimulated MEK activation determines the susceptibility of mitogen-activated protein (MAP) kinase to inhibition in rat aortic smooth muscle cells.
Topics: Angiotensin II; Animals; Aorta; Bradykinin; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Cell Line; Cells, Cultured; Colforsin; DNA; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Mitogen-Activated Protein Kinase Kinases; Muscle, Smooth; Muscle, Smooth, Vascular; Platelet-Derived Growth Factor; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Trachea | 1996 |
Galanin, neurotensin, and phorbol esters rapidly stimulate activation of mitogen-activated protein kinase in small cell lung cancer cells.
Topics: Bradykinin; Calcium-Calmodulin-Dependent Protein Kinases; Carcinogens; Carcinoma, Small Cell; Down-Regulation; Enzyme Activation; Flavonoids; Galanin; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Neoplasm Proteins; Neuropeptides; Neurotensin; Phorbol 12,13-Dibutyrate; Protein Kinase C; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Ribosomal Protein S6 Kinases; Tumor Cells, Cultured; Tumor Stem Cell Assay; Virulence Factors, Bordetella | 1996 |
Bradykinin stimulates cAMP synthesis via mitogen-activated protein kinase-dependent regulation of cytosolic phospholipase A2 and prostaglandin E2 release in airway smooth muscle.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cholera Toxin; Cyclic AMP; Cytosol; Dinoprostone; Down-Regulation; Drug Interactions; Flavonoids; Guinea Pigs; Indoles; Indomethacin; Maleimides; Muscle, Smooth; Phospholipases A; Phospholipases A2; Protein Kinase C; Signal Transduction; Tetradecanoylphorbol Acetate; Trachea | 1997 |
Agonist stimulation of B1 and B2 kinin receptors causes activation of the MAP kinase signaling pathway, resulting in the translocation of AP-1 in HEK 293 cells.
Topics: Animals; Biological Transport; Bradykinin; Bradykinin Receptor Antagonists; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Consensus Sequence; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Flavonoids; Humans; Oligonucleotides; Rats; Rats, Inbred BN; Rats, Sprague-Dawley; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Receptors, Bradykinin; Signal Transduction; Transcription Factor AP-1 | 1998 |
Medium change amplifies mitogen-activated protein kinase-mediated prostaglandin E2 synthesis in Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Bradykinin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Culture Media; Cytosol; Dinoprostone; Enzyme Inhibitors; Fibroblasts; Flavonoids; Genistein; Hydrolysis; Mice; Phosphatidylinositols; Phospholipases A; Phospholipases A2; Phosphorylation; Protein-Tyrosine Kinases; Tyrphostins | 1998 |
Bradykinin-stimulated protein synthesis by myocytes is dependent on the MAP kinase pathway and p70(S6K).
Topics: Angiotensin II; Animals; Bradykinin; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Flavonoids; Male; Muscle Proteins; Myocardium; Phenylalanine; Rats; Rats, Sprague-Dawley; Ribosomal Protein S6 Kinases; Sirolimus | 1999 |
Phosphorylation of WAVE downstream of mitogen-activated protein kinase signaling.
Topics: 3T3 Cells; Animals; Bradykinin; Cell Membrane; Enzyme Inhibitors; Flavonoids; Hepatocyte Growth Factor; Mice; Microfilament Proteins; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Phosphoproteins; Platelet-Derived Growth Factor; Recombinant Proteins; Signal Transduction; Wiskott-Aldrich Syndrome Protein Family | 1999 |
Bradykinin-regulated interactions of the mitogen-activated protein kinase pathway with the endothelial nitric-oxide synthase.
Topics: Androstadienes; Animals; Bradykinin; Cattle; Endothelium, Vascular; Enzyme Activation; Flavonoids; Gene Expression Regulation, Enzymologic; Mitogen-Activated Protein Kinases; Naphthalenes; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-raf; Receptor, Bradykinin B2; Receptors, Bradykinin; Wortmannin | 2000 |
Lipopolysaccharide enhances bradykinin-induced signal transduction via activation of Ras/Raf/MEK/MAPK in canine tracheal smooth muscle cells.
Topics: Animals; Binding, Competitive; Bradykinin; Calcium; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Female; Flavonoids; Imidazoles; Inositol Phosphates; Isoenzymes; Lipopolysaccharides; Male; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Pyridines; ras Proteins; Signal Transduction; Time Factors; Trachea; Tritium | 2000 |
Bradykinin stimulates IL-6 and IL-8 production by human lung fibroblasts through ERK- and p38 MAPK-dependent mechanisms.
Topics: Blotting, Northern; Blotting, Western; Bradykinin; Cells, Cultured; Enzyme Inhibitors; Fibroblasts; Flavonoids; Humans; Imidazoles; Interleukin-6; Interleukin-8; Lung; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA, Messenger; Signal Transduction | 2000 |
Mechanisms by which bradykinin promotes fibrosis in vascular smooth muscle cells: role of TGF-beta and MAPK.
Topics: Animals; Aorta; Bradykinin; Collagen; Enzyme Inhibitors; Fibrosis; Flavonoids; Gene Expression; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1; Transcriptional Activation; Transforming Growth Factor beta | 2000 |
In various tumour cell lines the peptide bradykinin B(2) receptor antagonist, Hoe 140 (Icatibant), may act as mitogenic agonist.
Topics: Bradykinin; Bradykinin Receptor Antagonists; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Inositol Phosphates; Mitogen-Activated Protein Kinases; Mitogens; Quinolines; Receptor, Bradykinin B2; Receptors, Bradykinin; Signal Transduction; Tumor Cells, Cultured | 2000 |
Tumour necrosis factor-alpha enhances bradykinin-induced signal transduction via activation of Ras/Raf/MEK/MAPK in canine tracheal smooth muscle cells.
Topics: Animals; Bradykinin; Calcium; Cells, Cultured; Dogs; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Inositol Phosphates; MAP Kinase Kinase 1; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Trachea; Tumor Necrosis Factor-alpha | 2001 |
Induction of B(1)-kinin receptors in vascular smooth muscle cells: cellular mechanisms of map kinase activation.
Topics: Animals; Bradykinin; Cells, Cultured; Cholera Toxin; Enzyme Activation; Flavonoids; Gene Expression Regulation; Indoles; Interleukin-1; Male; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Phosphorylation; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B1; Receptors, Bradykinin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Virulence Factors, Bordetella | 2001 |
Lack of involvement of extracellular signal-regulated kinase (ERK) in the agonist-induced endothelial nitric oxide synthesis.
Topics: Adenosine Triphosphate; Animals; Bradykinin; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Induction; Enzyme Inhibitors; Flavonoids; Mitogen-Activated Protein Kinases; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Swine | 2002 |
NECA and bradykinin at reperfusion reduce infarction in rabbit hearts by signaling through PI3K, ERK, and NO.
Topics: Adenosine A2 Receptor Antagonists; Adenosine-5'-(N-ethylcarboxamide); Androstadienes; Animals; Bradykinin; Caffeine; Enzyme Inhibitors; Flavonoids; In Vitro Techniques; Infarction; Mitogen-Activated Protein Kinases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rabbits; Receptors, Adenosine A2; Reperfusion; Signal Transduction; Vasodilator Agents; Wortmannin | 2004 |
Endothelial dysfunction and altered bradykinin response due to oxidative stress induced by serum deprivation in the bovine cerebral artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amides; Animals; Ascorbic Acid; Bradykinin; Cattle; Cerebral Arteries; Chromones; Culture Media; Culture Media, Serum-Free; Endothelium, Vascular; Enzyme Inhibitors; Flavonoids; Free Radical Scavengers; Genistein; Imidazoles; In Vitro Techniques; Indoles; Maleimides; Morpholines; Oxidative Stress; Potassium; Protein Kinase Inhibitors; Pyridines; Serum; Superoxide Dismutase; Time Factors; Vasoconstriction; Vasoconstrictor Agents; Vasodilation | 2004 |
Intracellular signalings underlying bradykinin-induced matrix metalloproteinase-9 expression in rat brain astrocyte-1.
Topics: Active Transport, Cell Nucleus; Animals; Astrocytes; Bradykinin; Cells, Cultured; Chromones; Flavonoids; Gene Expression Regulation; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Morpholines; NF-kappaB-Inducing Kinase; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Sesquiterpenes; Sesquiterpenes, Guaiane; Signal Transduction | 2004 |
Interleukin-4 increases murine airway response to kinins, via up-regulation of bradykinin B1-receptors and altered signalling along mitogen-activated protein kinase pathways.
Topics: Animals; Anthracenes; Bradykinin; Dactinomycin; Dexamethasone; Electromyography; Enzyme Inhibitors; Flavonoids; Imidazoles; In Vitro Techniques; Interleukin-4; Male; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle, Smooth; Pyridines; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Trachea | 2004 |
BK-induced cytosolic phospholipase A2 expression via sequential PKC-delta, p42/p44 MAPK, and NF-kappaB activation in rat brain astrocytes.
Topics: Acetophenones; Animals; Astrocytes; Benzopyrans; Bradykinin; Cell Line; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Kinase C-delta; Rats; Receptors, Bradykinin; RNA, Messenger; Sesquiterpenes; Sesquiterpenes, Guaiane | 2006 |
Tyrosine kinase and mitogen-activated protein kinase/extracellularly regulated kinase differentially regulate intracellular calcium concentration responses to angiotensin II/III and bradykinin in rat cortical thick ascending limb.
Topics: Angiotensin II; Angiotensin III; Animals; Bradykinin; Calcium; Cerebral Cortex; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Kinetics; Male; Mitogen-Activated Protein Kinase 1; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley | 2006 |
Protein kinase C (PKC)-delta/-epsilon mediate the PKC/Akt-dependent phosphorylation of extracellular signal-regulated kinases 1 and 2 in MCF-7 cells stimulated by bradykinin.
Topics: Analysis of Variance; Biological Transport; Bradykinin; Bradykinin B1 Receptor Antagonists; Bradykinin B2 Receptor Antagonists; Breast Neoplasms; Cell Line, Tumor; Cell Membrane; Cell Proliferation; Chromones; Cytosol; Dose-Response Relationship, Drug; Estrenes; Female; Flavonoids; Humans; Immunoblotting; Indoles; Kallidin; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase C beta; Protein Kinase C-delta; Protein Kinase C-epsilon; Pyrrolidinones; Stimulation, Chemical; Tetrahydroisoquinolines | 2006 |
The bradykinin B2 receptor mediates hypoxia/reoxygenation induced neuronal cell apoptosis through the ERK1/2 pathway.
Topics: Animals; Apoptosis; Bradykinin; Bradykinin B2 Receptor Antagonists; Cell Hypoxia; Cells, Cultured; Culture Media; Flavonoids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Oxygen; Phosphorylation; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Reperfusion Injury | 2009 |
Chronic bradykinin treatment alters 1α,25-dihydroxyvitamin D3-induced calcium current modulation in pre-osteoblasts.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Barium; Bone Resorption; Bradykinin; Calcitriol; Calcium; Calcium Channels, N-Type; Cell Line; Enzyme Activation; Flavonoids; Inflammation; Mice; Mitogen-Activated Protein Kinase Kinases; Osteoblasts; Patch-Clamp Techniques | 2012 |