pd 98059 has been researched along with benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 11 (73.33) | 29.6817 |
| 2010's | 3 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bilney, AJ; Hartfield, PJ; Murray, AW | 1 |
| Boushey, RP; Drucker, DJ; Yusta, B | 1 |
| Holbrook, NJ; Martindale, JL; Wang, X | 1 |
| Andreka, P; Bishopric, NH; Dougherty, C; Slepak, TI; Webster, KA; Zang, J | 1 |
| Chiba, H; Shimoke, K | 1 |
| Ahonen, M; Eriksson, JE; Holmstrom, TH; Kahari, VM; Tran, SE | 1 |
| Dent, P; Duigou, GJ; Ellis, E; Fisher, PB; Grant, S; Hagan, MP; Hinman, D; McKinstry, R; Park, JS; Qiao, L; Su, ZZ; Willoughby, K; Yacoub, A; Young, CS | 1 |
| Khwaja, A; Linch, DC; Somervaille, TC | 1 |
| Chong, A; Guo, Y; Ma, X; Regan, RF; Wang, Y | 1 |
| Arena, S; Benatti, U; Corsaro, A; Damonte, G; Florio, T; Millo, E; Schettini, G; Tagliavini, F; Thellung, S; Villa, V | 1 |
| Choi, AM; Chupp, GL; Flavell, RA; Lee, PJ; Sasidhar, M; Shan, P; Zhang, X | 1 |
| Kim, CH; Kim, JY; Kim, KS; Lee, BJ; Lee, JG; Song, KS; Yoon, JH | 1 |
| Agrawal, M; Bala Bhaskar, AS; Gupta, N; Lakshmana Rao, PV; Ravindran, J | 1 |
| Cho, SS; Im, HJ; Kim, CS; Kim, DK; Kim, JS; Kim, SG; Lee, SY; Moon, SM; Oh, JS; Park, MR; Yoon, G; You, JS | 1 |
| Han, Y; Liu, L; Luo, Y; Shi, X; Song, X; Wang, N; Xia, Y; Ye, T; Yu, L; Zeng, J; Zhu, Y | 1 |
15 other study(ies) available for pd 98059 and benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone
| Article | Year |
|---|---|
Neurotrophic factors prevent ceramide-induced apoptosis downstream of c-Jun N-terminal kinase activation in PC12 cells.
Topics: Amino Acid Chloromethyl Ketones; Androstadienes; Animals; Apoptosis; Cell Survival; Chromones; Cyclic AMP; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Fibroblast Growth Factor 2; Flavonoids; Hypoglycemic Agents; Insulin; Morpholines; Nerve Growth Factors; Neurons; Neuropeptides; Neuroprotective Agents; PC12 Cells; Pituitary Adenylate Cyclase-Activating Polypeptide; Protein Synthesis Inhibitors; Proto-Oncogene Proteins c-jun; Rats; Sphingosine; Thionucleotides; Wortmannin | 1998 |
The glucagon-like peptide-2 receptor mediates direct inhibition of cellular apoptosis via a cAMP-dependent protein kinase-independent pathway.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Division; Cell Line; Cell Survival; Chromones; Colforsin; Cricetinae; Cyclic AMP-Dependent Protein Kinases; Cycloheximide; Cysteine Proteinase Inhibitors; Cytochrome c Group; Cytosol; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Activation; Enzyme Inhibitors; Epithelium; Fibroblasts; Flavonoids; Glucagon-Like Peptide 2; Glucagon-Like Peptide-1 Receptor; Glucagon-Like Peptides; Intestinal Mucosa; Isoquinolines; Microscopy, Fluorescence; Mitochondria; Morpholines; Peptides; Poly(ADP-ribose) Polymerases; Protein Synthesis Inhibitors; Receptors, Cell Surface; Receptors, Glucagon; Signal Transduction; Sulfonamides; Time Factors; Transfection | 2000 |
Requirement for ERK activation in cisplatin-induced apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents; Apoptosis; Blotting, Western; Butadienes; Caspase 3; Caspases; Cell Line; Cell Survival; Cisplatin; Cysteine Proteinase Inhibitors; Cytochrome c Group; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; HeLa Cells; Humans; Indoles; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Nitriles; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Signal Transduction; Suramin; Tetradecanoylphorbol Acetate; Time Factors | 2000 |
Cytoprotection by Jun kinase during nitric oxide-induced cardiac myocyte apoptosis.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspase Inhibitors; Caspases; Cells, Cultured; Cyclic GMP; Cysteine Proteinase Inhibitors; DNA Fragmentation; DNA, Recombinant; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Glutathione; Imidazoles; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Myocardium; Nitric Oxide; Nitroso Compounds; Plasmids; Protein Serine-Threonine Kinases; Pyridines; S-Nitrosoglutathione; Transfection | 2001 |
Nerve growth factor prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced cell death via the Akt pathway by suppressing caspase-3-like activity using PC12 cells: relevance to therapeutical application for Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Amino Acid Chloromethyl Ketones; Amino Acid Substitution; Animals; Apoptosis; Caspase 3; Caspases; Chromones; Coumarins; Cysteine Proteinase Inhibitors; Dopamine Agents; Drug Evaluation, Preclinical; Enzyme Inhibitors; Flavonoids; Genes, Dominant; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Morpholines; Mutagenesis, Site-Directed; Neoplasm Proteins; Nerve Growth Factor; Oligopeptides; Parkinson Disease; Parkinsonian Disorders; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoserine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Recombinant Fusion Proteins; Signal Transduction; Transfection | 2001 |
MAPK/ERK overrides the apoptotic signaling from Fas, TNF, and TRAIL receptors.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspases; Cycloheximide; Cysteine Proteinase Inhibitors; DNA Fragmentation; Enzyme Activation; Enzyme Inhibitors; fas Receptor; Flavonoids; HeLa Cells; Humans; Kinetics; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Protein Serine-Threonine Kinases; Receptors, Tumor Necrosis Factor; Recombinant Proteins; Signal Transduction; Transfection; Tumor Necrosis Factor-alpha | 2001 |
Ionizing radiation modulates vascular endothelial growth factor (VEGF) expression through multiple mitogen activated protein kinase dependent pathways.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antigens, Differentiation; Apoptosis; Astrocytes; Cell Survival; Clone Cells; Endothelial Growth Factors; Flavonoids; Glioblastoma; Glioma; Lymphokines; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Radiation, Ionizing; Rats; Rats, Inbred F344; Signal Transduction; Transcription Factor AP-1; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2001 |
Growth factor withdrawal from primary human erythroid progenitors induces apoptosis through a pathway involving glycogen synthase kinase-3 and Bax.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; bcl-2-Associated X Protein; Calcium-Calmodulin-Dependent Protein Kinases; Caspase 3; Caspase Inhibitors; Cells, Cultured; Chromones; Colony-Forming Units Assay; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Erythroid Precursor Cells; Erythropoietin; Flavonoids; Glycogen Synthase Kinase 3; Glycogen Synthase Kinases; Humans; Isoenzymes; Lithium Chloride; MAP Kinase Kinase 1; MAP Kinase Signaling System; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase Kinases; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Conformation; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Stem Cell Factor | 2001 |
Activation of extracellular signal-regulated kinases potentiates hemin toxicity in astrocyte cultures.
Topics: Amino Acid Chloromethyl Ketones; Animals; Antioxidants; Astrocytes; Blood Proteins; Butadienes; Cell Survival; Cells, Cultured; Cerebral Cortex; Cysteine Proteinase Inhibitors; Enzyme Activation; Flavonoids; Free Radicals; Hemin; MAP Kinase Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinases; Nitriles; Oxidative Stress; Phenanthrolines; Pregnatrienes; Protease Inhibitors; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Signal Transduction | 2001 |
p38 MAP kinase mediates the cell death induced by PrP106-126 in the SH-SY5Y neuroblastoma cells.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspases; Cysteine Proteinase Inhibitors; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Neuroblastoma; Oligopeptides; p38 Mitogen-Activated Protein Kinases; Peptide Fragments; Prion Diseases; Prions; Pyridines; Tumor Cells, Cultured | 2002 |
Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspases; Cell Death; Cell Line, Transformed; Cysteine Proteinase Inhibitors; Electron Transport Complex IV; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Flavonoids; Hyperoxia; Lung; Mice; Mice, Knockout; Mitogen-Activated Protein Kinases; NADPH Oxidases; Onium Compounds; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Signal Transduction | 2003 |
Sulindac sulfide-induced apoptosis in sinonasal cancer cells.
Topics: Amino Acid Chloromethyl Ketones; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Carcinoma, Squamous Cell; Caspase Inhibitors; Flavonoids; Fluorescence; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Paranasal Sinus Neoplasms; Pyridines; Signal Transduction; Sulindac | 2005 |
Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Anthracenes; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Caspase 3; Caspase 7; Caspase 9; Cell Line, Tumor; Cyclosporins; Cytochromes c; DNA Damage; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutathione; Humans; Imidazoles; Immunoblotting; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Pyridines; Reactive Oxygen Species; U937 Cells | 2011 |
Licochalcone A induces apoptosis in KB human oral cancer cells via a caspase-dependent FasL signaling pathway.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Caspase 3; Caspase 8; Caspase Inhibitors; Cell Line, Tumor; Cell Survival; Chalcones; Chromatin; DNA Fragmentation; Extracellular Signal-Regulated MAP Kinases; Fas Ligand Protein; Flavonoids; Humans; Imidazoles; KB Cells; Keratinocytes; Mouth Neoplasms; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Pyridines; Signal Transduction | 2014 |
A novel small-molecule YLT205 induces apoptosis in human colorectal cells via mitochondrial apoptosis pathway in vitro and inhibits tumor growth in vivo.
Topics: Acetamides; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; bcl-2-Associated X Protein; Benzothiazoles; Cell Line, Tumor; Cell Survival; Colorectal Neoplasms; Cytochromes c; Down-Regulation; Flavonoids; HCT116 Cells; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitochondria; Phosphorylation; Transplantation, Heterologous | 2014 |