Compounds > pd 81723
Page last updated: 2024-09-03

pd 81723 and theophylline

pd 81723 has been researched along with theophylline in 4 studies

Compound Research Comparison

Studies
(pd 81723)		Trials
(pd 81723)		Recent Studies (post-2010)
(pd 81723)		Studies
(theophylline)		Trials
(theophylline)		Recent Studies (post-2010) (theophylline)
5501220,0761,6121,383

Protein Interaction Comparison

ProteinTaxonomypd 81723 (IC50)theophylline (IC50)
Adenosine receptor A1Bos taurus (cattle)2.43

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
IJzerman, AP; Kourounakis, AP; van der Klein, PA1
Bruns, RF; Montamat, SC; Mudumbi, RV; Vestal, RE1
Richardt, G; Schreieck, J1
de Ligt, RA; IJzerman, AP; Leurs, R; Lorenzen, A; Rivkees, SA1

Other Studies

4 other study(ies) available for pd 81723 and theophylline

ArticleYear
Allosteric modulation of the adenosine A(1) receptor. Synthesis and biological evaluation of novel 2-amino-3-benzoylthiophenes as allosteric enhancers of agonist binding.
    Journal of medicinal chemistry, 1999, Sep-09, Volume: 42, Issue:18

    Topics: Adenosine; Allosteric Regulation; Animals; Binding, Competitive; Brain; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Rats; Thiophenes; Xanthines

1999
Cardiac functional responses to adenosine by PD 81,723, an allosteric enhancer of the adenosine A1 receptor.
    The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 2

    Topics: Adenosine; Allosteric Regulation; Animals; Atrial Function; Depression, Chemical; Drug Synergism; Heart; Heart Atria; Heart Rate; Male; Myocardial Contraction; Rats; Rats, Sprague-Dawley; Receptors, Purinergic; Theophylline; Thiophenes; Xanthines

1993
Endogenous adenosine reduces the occurrence of ischemia-induced ventricular fibrillation in rat heart.
    Journal of molecular and cellular cardiology, 1999, Volume: 31, Issue:1

    Topics: Adenine; Adenosine; Aminoimidazole Carboxamide; Animals; Caffeine; Creatine Kinase; Electrocardiography; Enzyme Inhibitors; Hypoxanthine; Inosine; Male; Myocardial Ischemia; Myocardium; Perfusion; Rats; Rats, Wistar; Reperfusion Injury; Ribonucleosides; Theophylline; Thioinosine; Thiophenes; Time Factors; Ventricular Fibrillation; Xanthines

1999
A "locked-on," constitutively active mutant of the adenosine A1 receptor.
    European journal of pharmacology, 2005, Mar-07, Volume: 510, Issue:1-2

    Topics: Adenosine; Animals; Binding, Competitive; Cell Line; Cell Membrane; Chlorocebus aethiops; Colforsin; COS Cells; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Kinetics; Mutation; Plasmids; Radioligand Assay; Receptor, Adenosine A1; Sodium; Sulfur Radioisotopes; Theophylline; Thiophenes; Transfection; Tritium; Xanthines

2005