pd 173074 and su 5402
pd 173074 has been researched along with su 5402 in 8 studies
Research
Studies (8)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Chanda, SK; DeJesus, PD; Izpisúa Belmonte, JC; Luesch, H; Orth, AP; Raya, RM; Schultz, PG; Walker, JR | 1 |
| Cheng, W; Tian, X; Wang, M; Zhang, X | 1 |
| Doherty, P; Facci, L; Kee, WJ; Macdonald, G; Skaper, SD; Walsh, FS | 1 |
| Chase, AJ; Cross, NC; Grand, EK; Heath, C; Rahemtulla, A | 1 |
| Bachmann, AW; Hutley, LJ; Newell, FS; Prins, JB; Ramnoruth, SN; Spelta, MC; Whitehead, JP; Widberg, CH | 1 |
| Chester, JD; Cooper, PA; Knowles, MA; Lamont, FR; Shnyder, SD; Tomlinson, DC | 1 |
| Ealy, AD; Zhang, K | 1 |
| Balek, L; Buchtova, M; Dosedelova, H; Gudernova, I; Jelinkova, I; Kozubik, A; Krejci, P; Kunova, M; Pivnicka, J; Roubalova, L; Vesela, I | 1 |
Reviews
1 review(s) available for pd 173074 and su 5402
| Article | Year |
|---|---|
An overview of the binding models of FGFR tyrosine kinases in complex with small molecule inhibitors.
Topics: Humans; Protein Binding; Protein Kinase Inhibitors; Receptor Protein-Tyrosine Kinases; Small Molecule Libraries | 2017 |
Other Studies
7 other study(ies) available for pd 173074 and su 5402
| Article | Year |
|---|---|
A functional genomics approach to the mode of action of apratoxin A.
Topics: Animals; Apoptosis; Cell Cycle; Cell Proliferation; Depsipeptides; Drug Resistance, Neoplasm; Endothelial Cells; Fibroblast Growth Factors; G1 Phase; Gene Expression Regulation; Genomics; Humans; In Vitro Techniques; Molecular Conformation; Phosphorylation; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Structure-Activity Relationship; Transcription, Genetic; Tumor Cells, Cultured; Zebrafish | 2006 |
The FGFR1 inhibitor PD 173074 selectively and potently antagonizes FGF-2 neurotrophic and neurotropic effects.
Topics: Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Chick Embryo; Ciliary Neurotrophic Factor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibroblast Growth Factor 2; Glial Cell Line-Derived Neurotrophic Factor; Insulin-Like Growth Factor I; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Nerve Growth Factors; Nerve Tissue Proteins; Neurites; Neurons; PC12 Cells; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Sensitivity and Specificity | 2000 |
Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074.
Topics: Cell Line, Tumor; Chromosomes, Human, Pair 14; Chromosomes, Human, Pair 4; Humans; Multiple Myeloma; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; Translocation, Genetic | 2004 |
Fibroblast growth factor receptor 1 is a key regulator of early adipogenic events in human preadipocytes.
Topics: Adipocytes; Adipogenesis; Adipose Tissue; Adult; Aged; Becaplermin; Cell Growth Processes; Female; Fibroblast Growth Factor 1; Humans; Male; Middle Aged; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Pyrimidines; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A | 2009 |
Small molecule FGF receptor inhibitors block FGFR-dependent urothelial carcinoma growth in vitro and in vivo.
Topics: Animals; Apoptosis; Benzimidazoles; Blotting, Western; Carcinoma, Transitional Cell; Cell Cycle; Cell Proliferation; Cells, Cultured; Humans; Immunoenzyme Techniques; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Mutation; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Quinolones; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 3; Urinary Bladder Neoplasms; Urothelium; Xenograft Model Antitumor Assays | 2011 |
Disruption of fibroblast growth factor receptor signaling in bovine cumulus-oocyte complexes during in vitro maturation reduces subsequent embryonic development.
Topics: Animals; Cattle; Cumulus Cells; Embryonic Development; Female; Fertilization in Vitro; Oocytes; Pregnancy; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Real-Time Polymerase Chain Reaction; Receptors, Fibroblast Growth Factor; RNA; Signal Transduction | 2012 |
Multikinase activity of fibroblast growth factor receptor (FGFR) inhibitors SU5402, PD173074, AZD1480, AZD4547 and BGJ398 compromises the use of small chemicals targeting FGFR catalytic activity for therapy of short-stature syndromes.
Topics: Achondroplasia; Animals; Benzamides; Cartilage; Catalysis; Cells, Cultured; Chick Embryo; Chondrocytes; Humans; Mice; Phenylurea Compounds; Piperazines; Pyrazoles; Pyrimidines; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; Signal Transduction; Syndrome | 2016 |