pd 153035 has been researched along with epidermal growth factor in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (25.64) | 18.2507 |
| 2000's | 22 (56.41) | 29.6817 |
| 2010's | 7 (17.95) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ambroso, LA; Bridges, AJ; Connors, RW; Fry, DW; Kraker, AJ; Leopold, WR; McMichael, A; Nelson, JM | 1 |
| Bridges, AJ; Cody, DR; Denny, WA; Fry, DW; Kraker, AJ; McMichael, A; Rewcastle, GW; Showalter, HD; Zhou, H | 1 |
| Hollenberg, MD; Zheng, XL | 1 |
| Fridman, R; Kondapaka, SB; Reddy, KB | 1 |
| Elder, J; Garner, W; Stoll, S | 1 |
| Hamacher, L; Peus, D; Pittelkow, MR | 1 |
| Hollenberg, MD; Renaux, B; Zheng, XL | 1 |
| Earp, HS; Graves, LM; Lee, JW; Li, X | 1 |
| Ahola, H; Carlstedt-Duke, J; Modéer, T; Yucel-Lindberg, T | 1 |
| Greenberg, NM; Kassis, J; Kim, HG; Lo, H; Moellinger, J; Wells, A | 1 |
| Diao, C; Hollenberg, MD; Matsubara, S; Wong, NC; Zheng, XL | 1 |
| Klar, U; Lichtner, RB; Menrad, A; Schneider, MR; Sommer, A | 1 |
| Bulloch, AG; Hermann, PM; Wildering, WC | 1 |
| Katoh, O; Lu, H; Uesaka, T; Watanabe, H | 1 |
| Hénichart, JP; Mimeault, M; Pommery, N | 1 |
| Conzen, SD; Coticchia, CM; Dickson, RB; Nishanian, TG; Ramljak, D; Ringel, MD; Saji, M | 1 |
| Bromberg, PA; Dailey, LA; Graves, LM; Samet, JM; Sheppard, D; Silbajoris, R; Wu, W | 1 |
| Diggle, C; Holder, J; Lee, WC; Selby, PJ; Southgate, J; Stahlschmidt, J; Trejdosiewicz, LK; Varley, CL | 1 |
| Cho, YM; Foley, J; Gocken, TA; Koltz, PF; Konger, RL; Lewis, DA; Richard, V; Rosol, TJ; Spandau, DF | 1 |
| Bazan, HE; Bazan, NG; Ottino, P; Sharma, GD | 1 |
| Hill, G; Pellegrin, S; Selby, PJ; Shaw, NJ; Southgate, J; Trejdosiewicz, LK; Varley, C | 1 |
| Derby, S; Di, W; Jiang, Q; Qiu, L; Schefeller, E; Wan, Y; Wanebo, H; Wang, Q; Yan, B | 1 |
| Iwakura, Y; Jourdi, H; Nagano, T; Namba, H; Nawa, H; Takei, N; Xiong, H | 1 |
| Gallo, RM; Gilmore, JL; Riese, DJ | 1 |
| Chen, H; Fan, ST; Kok, TW; Liu, Y; Poon, RT; Shao, W; Sun, X | 1 |
| Cereijido, M; Contreras, RG; Flores-Benítez, D; Flores-Maldonado, C; Ruiz-Cabrera, A; Shoshani, L | 1 |
| Hofer, HW; Pfeiffer, T; Schreiner, D; Stenzinger, A; Tag, C; Wimmer, M | 1 |
| Bassuk, JA; Carmean, N; Hudson, AE; Kosman, JW; Leaf, EM; Opheim, KE | 1 |
| Amaral, A; Cao, C; Chu, W; Di, W; Kivlin, R; Lu, S; Sowa, A; Wan, Y; Yang, H | 1 |
| Bi, K; Echeverria, VM; Honer, J; Machleidt, T; Vandenheuvel-Kramer, K; Wilkinson, JM; Zhong, Z | 1 |
| Iyengar, L; Lovicu, FJ; McAvoy, JW; Patkunanathan, B | 1 |
| Kawanishi, M; Koizumi, K; Nishimura, M; Saiki, I; Sakurai, H; Shin, MS; Singhirunnusorn, P; Suzuki, S | 1 |
| Partridge, NC; Qin, L; Shimizu, E; Zhang, X; Zhu, J | 1 |
| Gong, K; Li, X; Liu, W; Luo, K; Wang, K | 1 |
| Eda, T; Iwakura, Y; Mizuno, M; Nagata, K; Namba, H; Nawa, H; Okubo, T; Shibuya, M; Sotoyama, H; Wang, R | 1 |
| Arndt-Jovin, DJ; Bunt, G; Fritsch, C; Jovin, TM; Klement, R; Klymchenko, AS; Loman, A; Ziomkiewicz, I | 1 |
| Leon Carrion, S; Sutter, CH; Sutter, TR | 1 |
| Campion, CM; Cole, JA; Leon Carrion, S; Mamidanna, G; Sutter, CH; Sutter, TR | 1 |
| Abisoye-Ogunniyan, A; Davis, M; Ghebremedhin, A; Grizzle, W; Jones-Trich, J; Karanam, B; Lin, H; Salam, AB; Theodore, S; Wang, H; Yates, C | 1 |
39 other study(ies) available for pd 153035 and epidermal growth factor
| Article | Year |
|---|---|
A specific inhibitor of the epidermal growth factor receptor tyrosine kinase.
Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Epidermal Growth Factor; ErbB Receptors; Fibroblast Growth Factor 2; Gene Expression; Humans; Kinetics; Mice; Mitosis; Phosphorylation; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Quinazolines; Tumor Cells, Cultured; Tyrosine | 1994 |
Tyrosine kinase inhibitors. 8. An unusually steep structure-activity relationship for analogues of 4-(3-bromoanilino)-6,7-dimethoxyquinazoline (PD 153035), a potent inhibitor of the epidermal growth factor receptor.
Topics: Aniline Compounds; Binding Sites; Blotting, Western; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Kinetics; Molecular Conformation; Molecular Structure; Phosphorylation; Protein Binding; Quinazolines; Structure-Activity Relationship; Tumor Cells, Cultured | 1996 |
Tyrosine kinase inhibitor-sensitive contractile action of ethanol in gastric smooth muscle: comparison with the action of epidermal growth factor.
Topics: 1-Propanol; Animals; Calcium; Catechols; Cyclohexanones; Enzyme Inhibitors; Epidermal Growth Factor; Ethanol; Fomepizole; Genistein; Guinea Pigs; Humans; In Vitro Techniques; Indoles; Indomethacin; Isoflavones; Male; Maleimides; Methanol; Muscle Contraction; Muscle, Smooth; Nitriles; Protein-Tyrosine Kinases; Pyrazoles; Quinazolines; Signal Transduction; Stomach; Tyrphostins | 1997 |
Epidermal growth factor and amphiregulin up-regulate matrix metalloproteinase-9 (MMP-9) in human breast cancer cells.
Topics: Amphiregulin; Antineoplastic Agents; Breast Neoplasms; Cell Division; Collagenases; EGF Family of Proteins; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gelatinases; Glycoproteins; Growth Substances; Humans; Intercellular Signaling Peptides and Proteins; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Metalloendopeptidases; Neoplasm Invasiveness; Neoplasm Metastasis; Quinazolines; Tumor Cells, Cultured; Up-Regulation | 1997 |
Heparin-binding ligands mediate autocrine epidermal growth factor receptor activation In skin organ culture.
Topics: Adult; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Gene Expression; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Organ Culture Techniques; Quinazolines; Skin; Wound Healing | 1997 |
EGF-receptor tyrosine kinase inhibition induces keratinocyte growth arrest and terminal differentiation.
Topics: Antibodies, Monoclonal; Cell Differentiation; Cell Division; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Humans; Keratinocytes; Phosphorylation; Quinazolines | 1997 |
Parallel contractile signal transduction pathways activated by receptors for thrombin and epidermal growth factor-urogastrone in guinea pig gastric smooth muscle: blockade by inhibitors of mitogen-activated protein kinase-kinase and phosphatidyl inositol
Topics: Animals; Arachidonic Acid; Calcium; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Guinea Pigs; Lipoprotein Lipase; Male; Mitogen-Activated Protein Kinase Kinases; Muscle Contraction; Muscle, Smooth, Vascular; Phosphatidylinositols; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Receptors, Thrombin; Signal Transduction | 1998 |
Angiotensin II stimulates ERK via two pathways in epithelial cells: protein kinase C suppresses a G-protein coupled receptor-EGF receptor transactivation pathway.
Topics: Angiotensin II; Animals; Cell Line; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; GTP-Binding Proteins; Humans; Liver; Protein Kinase C; Protein-Tyrosine Kinases; Quinazolines; Rats; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Transcriptional Activation | 1998 |
Involvement of tyrosine kinases on cyclooxygenase expression and prostaglandin E2 production in human gingival fibroblasts stimulated with interleukin-1beta and epidermal growth factor.
Topics: Benzoquinones; Cells, Cultured; Child; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Drug Synergism; Epidermal Growth Factor; Fibroblasts; Gene Expression Regulation; Gingiva; Humans; Interleukin-1; Isoenzymes; Lactams, Macrocyclic; Membrane Proteins; Nitrobenzenes; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Quinazolines; Quinones; Rifabutin; RNA, Messenger; Sulfonamides; Time Factors | 1999 |
A role for phospholipase C-gamma-mediated signaling in tumor cell invasion.
Topics: Adenocarcinoma; Animals; Autocrine Communication; Breast Neoplasms; Cell Line; Diffusion Chambers, Culture; Epidermal Growth Factor; ErbB Receptors; Estrenes; Female; Humans; Immunoblotting; Isoenzymes; Male; Mice; Neoplasm Invasiveness; Phosphodiesterase Inhibitors; Phospholipase C gamma; Phosphorylation; Prostatic Neoplasms; Pyrrolidinones; Quinazolines; Receptor, ErbB-2; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Type C Phospholipases | 1999 |
Epidermal growth factor induction of apolipoprotein A-I is mediated by the Ras-MAP kinase cascade and Sp1.
Topics: Amino Acid Sequence; Apolipoprotein A-I; Binding Sites; Blotting, Western; Chloramphenicol O-Acetyltransferase; Cycloheximide; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genes, Dominant; Genes, ras; Genes, Reporter; Humans; Insulin; MAP Kinase Signaling System; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Plasmids; Protein Binding; Protein Kinase C; Protein Synthesis Inhibitors; Quinazolines; ras Proteins; Retroviridae; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Sp1 Transcription Factor; Threonine; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Up-Regulation | 2001 |
Signaling-inactive epidermal growth factor receptor/ligand complexes in intact carcinoma cells by quinazoline tyrosine kinase inhibitors.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gefitinib; Humans; Kinetics; Ligands; Lung Neoplasms; Mammary Neoplasms, Experimental; Phthalimides; Quinazolines; Rats; Signal Transduction; Tumor Cells, Cultured | 2001 |
Lymnaea epidermal growth factor promotes axonal regeneration in CNS organ culture.
Topics: Animals; Axons; Carbazoles; Central Nervous System; Disease Models, Animal; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Indole Alkaloids; Lymnaea; Nerve Crush; Nerve Regeneration; Neurons; Organ Culture Techniques; Quinazolines; Reproducibility of Results | 2001 |
Heparin-binding EGF-like growth factor gene transcription regulated by Cdx2 in the intestinal epithelium.
Topics: Animals; CDX2 Transcription Factor; Cell Division; Cell Line; Cell Movement; Enzyme Inhibitors; Epidermal Growth Factor; Gene Expression; Gene Expression Regulation; Heparin; Heparin-binding EGF-like Growth Factor; Homeodomain Proteins; Intercellular Signaling Peptides and Proteins; Intestinal Mucosa; Male; Mice; Promoter Regions, Genetic; Quinazolines; Rats; Reverse Transcriptase Polymerase Chain Reaction; Trans-Activators; Transcription, Genetic; Transfection | 2002 |
Synergistic antiproliferative and apoptotic effects induced by epidermal growth factor receptor and protein kinase a inhibitors in human prostatic cancer cell lines.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; Cell Division; Cell Separation; Ceramides; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; ErbB Receptors; Flow Cytometry; Humans; Male; Membrane Potentials; Mitochondria; Necrosis; Prostatic Neoplasms; Protease Inhibitors; Quinazolines; Tumor Cells, Cultured | 2003 |
Epidermal growth factor inhibition of c-Myc-mediated apoptosis through Akt and Erk involves Bcl-xL upregulation in mammary epithelial cells.
Topics: Animals; Apoptosis; bcl-X Protein; Butadienes; Cell Line; Chromones; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Quinazolines; Up-Regulation | 2003 |
Heparin-binding epidermal growth factor cleavage mediates zinc-induced epidermal growth factor receptor phosphorylation.
Topics: Antibodies; Bronchi; Cells, Cultured; Dipeptides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Ligands; Matrix Metalloproteinase Inhibitors; Phosphorylation; Quinazolines; Tyrosine; Zinc | 2004 |
Role of PPARgamma and EGFR signalling in the urothelial terminal differentiation programme.
Topics: Active Transport, Cell Nucleus; Adipocytes; Anilides; Animals; Blotting, Western; Cattle; Cell Differentiation; Cell Line; Cell Proliferation; Chromans; Enzyme Inhibitors; Epidermal Growth Factor; Epithelium; ErbB Receptors; Gene Expression Regulation; Humans; Immunoprecipitation; Ligands; Membrane Glycoproteins; Membrane Proteins; Microscopy, Fluorescence; Phosphorylation; PPAR gamma; Promoter Regions, Genetic; Quinazolines; Ribonucleases; RNA, Messenger; Signal Transduction; Thiazolidinediones; Time Factors; Troglitazone; Uroplakin Ia; Uroplakin Ib; Uroplakin II; Uroplakin III; Urothelium | 2004 |
Regulation of parathyroid hormone-related protein gene expression by epidermal growth factor-family ligands in primary human keratinocytes.
Topics: Adult; Amphiregulin; Antibodies, Monoclonal; Bacterial Proteins; Cell Division; Cells, Cultured; Dactinomycin; EGF Family of Proteins; Epidermal Growth Factor; Epidermis; ErbB Receptors; Gene Expression Regulation; Genes, erbB-1; Glycoproteins; Heparin-binding EGF-like Growth Factor; Humans; Infant, Newborn; Intercellular Signaling Peptides and Proteins; Keratinocytes; Parathyroid Hormone-Related Protein; Quinazolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Transforming Growth Factor alpha | 2004 |
Epidermal and hepatocyte growth factors, but not keratinocyte growth factor, modulate protein kinase Calpha translocation to the plasma membrane through 15(S)-hydroxyeicosatetraenoic acid synthesis.
Topics: Arachidonate 15-Lipoxygenase; Blotting, Western; Cell Membrane; Cell Proliferation; Cells, Cultured; Chromatography, High Pressure Liquid; Cornea; Cytosol; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Fibroblast Growth Factor 7; Fibroblast Growth Factors; Green Fluorescent Proteins; Hepatocyte Growth Factor; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Lipoxygenase; MAP Kinase Kinase Kinases; Microscopy, Fluorescence; Models, Biological; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Transport; Quinazolines; Signal Transduction; Time Factors; Transfection; Wound Healing | 2005 |
Autocrine regulation of human urothelial cell proliferation and migration during regenerative responses in vitro.
Topics: Amphiregulin; Antibodies; Autocrine Communication; Cell Cycle; Cell Movement; Cell Proliferation; Cells, Cultured; EGF Family of Proteins; Enzyme Inhibitors; Epidermal Growth Factor; Epiregulin; ErbB Receptors; Gene Expression; Glycoproteins; Growth Substances; Heparin-binding EGF-like Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; MAP Kinase Signaling System; Quinazolines; Regeneration; Transforming Growth Factor alpha; Urothelium; Wound Healing | 2005 |
Transient activation of EGFR/AKT cell survival pathway and expression of survivin contribute to reduced sensitivity of human melanoma cells to betulinic acid.
Topics: Animals; Antineoplastic Agents, Phytogenic; Betulinic Acid; Blotting, Western; Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; Drug Resistance, Neoplasm; Drug Synergism; Embryo, Mammalian; Epidermal Growth Factor; ErbB Receptors; Fibroblasts; Humans; Inhibitor of Apoptosis Proteins; Keratinocytes; Melanoma; Mice; Mice, Knockout; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Proteins; Pentacyclic Triterpenes; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Quinazolines; Survivin; Time Factors; Triterpenes | 2005 |
Transforming growth factor alpha attenuates the functional expression of AMPA receptors in cortical GABAergic neurons.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Cerebral Cortex; Culture Media, Serum-Free; Electrophysiology; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; gamma-Aminobutyric Acid; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Ligands; Neurons; Protein Subunits; Quinazolines; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Transforming Growth Factor alpha | 2006 |
The epidermal growth factor receptor (EGFR)-S442F mutant displays increased affinity for neuregulin-2beta and agonist-independent coupling with downstream signalling events.
Topics: Amino Acid Substitution; Animals; Apoptosis; Binding Sites; Cell Line; Chromones; Epidermal Growth Factor; ErbB Receptors; Genes, erbB-1; Humans; Hydrophobic and Hydrophilic Interactions; Ligands; Mice; Morpholines; Mutation, Missense; Myeloid Cells; Neuregulins; Phosphatidylinositol 3-Kinases; Phosphorylation; Point Mutation; Protein Binding; Protein Interaction Mapping; Protein Processing, Post-Translational; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quinazolines; Recombinant Fusion Proteins; Signal Transduction; Transfection | 2006 |
Blockage of epidermal growth factor receptor by quinazoline tyrosine kinase inhibitors suppresses growth of human hepatocellular carcinoma.
Topics: Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Flow Cytometry; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines | 2007 |
Control of tight junctional sealing: role of epidermal growth factor.
Topics: Adolescent; Adult; Animals; Cell Membrane Permeability; Cells, Cultured; Claudin-1; Claudin-4; Dogs; Electric Impedance; Epidermal Growth Factor; ErbB Receptors; Humans; Male; Membrane Proteins; Quinazolines; Tight Junctions | 2007 |
Epidermal growth factor-, transforming growth factor-beta-, retinoic acid- and 1,25-dihydroxyvitamin D3-regulated expression of the novel protein PTPIP51 in keratinocytes.
Topics: Calcitriol; Cell Line; Cell Nucleus; Cytoplasm; Epidermal Growth Factor; Gene Expression Regulation; Humans; Keratinocytes; Mitochondrial Proteins; Protein Tyrosine Phosphatases; Quinazolines; RNA, Messenger; Transforming Growth Factor beta; Tretinoin | 2006 |
Immortalization of human urothelial cells by human papillomavirus type 16 E6 and E7 genes in a defined serum-free system.
Topics: Animals; Cell Cycle; Cell Growth Processes; Cell Line, Transformed; Cell Transformation, Viral; Cells, Cultured; Clone Cells; Culture Media, Serum-Free; Epidermal Growth Factor; ErbB Receptors; Genes, Viral; Human papillomavirus 16; Humans; Karyotyping; Keratins; Mice; Oncogene Proteins, Viral; Papillomavirus E7 Proteins; Papillomavirus Infections; Phenotype; Quinazolines; Repressor Proteins; Telomerase; Urothelium | 2007 |
Priming with EGFR tyrosine kinase inhibitor and EGF sensitizes ovarian cancer cells to respond to chemotherapeutical drugs.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Cell Proliferation; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Female; Mice; Ovarian Neoplasms; Paclitaxel; Protein Kinase Inhibitors; Quinazolines; Signal Transduction | 2008 |
HTS assays using a disease-relevant cell model for interrogating the MAP kinase pathway initiated by multiple receptors.
Topics: Cell Line, Tumor; Epidermal Growth Factor; Female; Hepatocyte Growth Factor; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Proto-Oncogene Proteins; Quinazolines; Receptors, Cell Surface | 2008 |
Growth factors involved in aqueous humour-induced lens cell proliferation.
Topics: Animals; Aqueous Humor; Cell Proliferation; Cells, Cultured; Epidermal Growth Factor; Epithelial Cells; Fibroblast Growth Factors; Insulin-Like Growth Factor I; Intercellular Signaling Peptides and Proteins; Lens, Crystalline; Platelet-Derived Growth Factor; Pyrroles; Quinazolines; Rats; Rats, Wistar; Signal Transduction; Tyrphostins | 2009 |
TAK1-mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal-regulated kinase: NF-{kappa}B-independent survival pathways in tumor necrosis factor alpha signaling.
Topics: Anthracenes; Butadienes; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; HeLa Cells; Humans; Imidazoles; Lactones; MAP Kinase Kinase Kinases; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Quinazolines; Resorcinols; RNA, Small Interfering; Serine; Signal Transduction; Threonine; Tumor Necrosis Factor-alpha | 2009 |
EGFR signaling suppresses osteoblast differentiation and inhibits expression of master osteoblastic transcription factors Runx2 and Osterix.
Topics: 3T3 Cells; Alkaline Phosphatase; Amphiregulin; Animals; Cell Differentiation; Core Binding Factor Alpha 1 Subunit; EGF Family of Proteins; Epidermal Growth Factor; ErbB Receptors; Genetic Markers; Glycoproteins; Heparin-binding EGF-like Growth Factor; Histone Deacetylase 6; Histone Deacetylases; Humans; Integrin-Binding Sialoprotein; Intercellular Signaling Peptides and Proteins; Mice; Neuregulin-1; Osteoblasts; Osteocalcin; Osteogenesis; Quinazolines; Signal Transduction; Sp7 Transcription Factor; Transcription Factors; Transcription, Genetic; Transforming Growth Factor alpha | 2011 |
Epidermal growth factor enhances MPC-83 pancreatic cancer cell migration through the upregulation of aquaporin 3.
Topics: Antineoplastic Agents; Aquaporin 3; Butadienes; Cell Line, Tumor; Cell Movement; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Humans; Nitriles; Pancreatic Neoplasms; Phosphorylation; Quinazolines; Up-Regulation | 2012 |
ErbB inhibitors ameliorate behavioral impairments of an animal model for schizophrenia: implication of their dopamine-modulatory actions.
Topics: Animals; Antipsychotic Agents; Brain Chemistry; Disease Models, Animal; Dopaminergic Neurons; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Female; Gefitinib; Male; Motor Activity; Quinazolines; Rats; Rats, Sprague-Dawley; Reflex, Startle; Schizophrenia; Schizophrenic Psychology | 2013 |
Dynamic conformational transitions of the EGF receptor in living mammalian cells determined by FRET and fluorescence lifetime imaging microscopy.
Topics: Animals; Cell Membrane; CHO Cells; Cricetulus; Endocytosis; Epidermal Growth Factor; ErbB Receptors; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Microscopy, Fluorescence; Models, Molecular; Molecular Dynamics Simulation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Quinazolines; Recombinant Proteins | 2013 |
Combined treatment with sodium butyrate and PD153035 enhances keratinocyte differentiation.
Topics: Antineoplastic Agents; Butyric Acid; Cell Differentiation; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Filaggrin Proteins; Histamine Antagonists; Humans; Intermediate Filament Proteins; Keratinocytes; Quinazolines; RNA, Messenger; Transglutaminases | 2014 |
Role of EGF receptor ligands in TCDD-induced EGFR down-regulation and cellular proliferation.
Topics: Amphiregulin; Cell Proliferation; Cells, Cultured; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Epidermal Growth Factor; ErbB Receptors; Humans; Iodine Radioisotopes; Ligands; Polychlorinated Dibenzodioxins; Protein Binding; Quinazolines; Transforming Growth Factor alpha | 2016 |
Transcriptional repressor Kaiso promotes epithelial to mesenchymal transition and metastasis in prostate cancer through direct regulation of miR-200c.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; ErbB Receptors; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Mice; Mice, Nude; MicroRNAs; Neoplasm Metastasis; Neoplasm Transplantation; Prostatic Neoplasms; Quinazolines; Transcription Factors | 2018 |