pd 145065 has been researched along with pd 142893 in 5 studies
| Studies (pd 145065) | Trials (pd 145065) | Recent Studies (post-2010) (pd 145065) | Studies (pd 142893) | Trials (pd 142893) | Recent Studies (post-2010) (pd 142893) |
|---|---|---|---|---|---|
| 76 | 1 | 5 | 64 | 0 | 3 |
| Protein | Taxonomy | pd 145065 (IC50) | pd 142893 (IC50) |
|---|---|---|---|
| Polyunsaturated fatty acid 5-lipoxygenase | Homo sapiens (human) | 4.4 | |
| Endothelin receptor type B | Rattus norvegicus (Norway rat) | 3.95 | |
| Endothelin receptor type B | Homo sapiens (human) | 4.4 | |
| Endothelin-1 receptor | Homo sapiens (human) | 4.1 | |
| Endothelin-1 receptor | Rattus norvegicus (Norway rat) | 4.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, XM; Cody, WL; Davis, LS; DePue, PL; Doherty, AM; Flynn, MA; He, JX; LaDouceur, DM; Reynolds, EE; Welch, KM | 1 |
| Cahoon, NM; Clarke, FH | 1 |
| Cody, WL; Doherty, AM; Hayes, RN; He, JX; Reyner, EL; Stewart, BH; Tse, E; Werness, S | 1 |
| Curtis, LA; Holm, AS; Holmes, EP; Koch, CE; Moore, RM; Venugopal, CS | 1 |
| Eades, SC; Hosgood, G; Moore, RM; Stokes, AM; Venugopal, CS | 1 |
5 other study(ies) available for pd 145065 and pd 142893
| Article | Year |
|---|---|
In vitro and in vivo studies with a series of hexapeptide endothelin antagonists.
Topics: Amino Acid Sequence; Animals; Arachidonic Acid; Azepines; Endothelin Receptor Antagonists; Endothelins; Ganglionic Blockers; Hemodynamics; In Vitro Techniques; Indoles; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Rabbits; Rats; Receptors, Endothelin; Structure-Activity Relationship; Vasoconstriction | 1993 |
Potentiometric determination of the partition and distribution coefficients of dianionic compounds.
Topics: Amino Acid Sequence; Endothelin Receptor Antagonists; Endothelins; Hydrogen-Ion Concentration; Molecular Sequence Data; Octanols; Oligopeptides; Potentiometry; Solubility | 1995 |
In vitro assessment of oral delivery for hexapeptide endothelin antagonists.
Topics: Animals; Captopril; Chromatography, High Pressure Liquid; Competitive Bidding; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; In Vitro Techniques; Male; Oligopeptides; Permeability; Rats; Rats, Wistar | 1996 |
In vitro pharmacologic effect of two endothelin-1 antagonists on equine colonic arteries and veins.
Topics: Animals; Arteries; Colon; Dose-Response Relationship, Drug; Drug Synergism; Endothelin-1; Horses; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Vasoconstriction; Veins | 2001 |
Comparison of 2 endothelin-receptor antagonists on in vitro responses of equine palmar digital arterial and venous rings to endothelin-1.
Topics: Animals; Arteries; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Horses; In Vitro Techniques; Muscle, Smooth, Vascular; Oligopeptides; Toes; Veins | 2006 |