Page last updated: 2024-09-03

pd 145065 and ng-nitroarginine methyl ester

pd 145065 has been researched along with ng-nitroarginine methyl ester in 6 studies

Compound Research Comparison

Studies
(pd 145065)
Trials
(pd 145065)
Recent Studies (post-2010)
(pd 145065)
Studies
(ng-nitroarginine methyl ester)
Trials
(ng-nitroarginine methyl ester)
Recent Studies (post-2010) (ng-nitroarginine methyl ester)
761512,6401172,342

Protein Interaction Comparison

ProteinTaxonomypd 145065 (IC50)ng-nitroarginine methyl ester (IC50)
Neutrophil elastaseHomo sapiens (human)2.7
Nitric oxide synthase, endothelialHomo sapiens (human)2.1
Nitric oxide synthase, brainHomo sapiens (human)1.1167
Nitric oxide synthase, inducibleMus musculus (house mouse)2.6
Nitric oxide synthase, inducibleHomo sapiens (human)8
Collagenase 3Homo sapiens (human)2.7

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adams, MA; Banting, JD; Friberg, P1
Bhargava, J; Di Luozzo, G; Powell, RJ1
Kadekaro, M; Salas, N; Summy-Long, JY; Terrell, ML1
Chong, T; Ramirez, R; Victorino, GP1
Cupples, WA; Lau, C; Shi, Y1
Adams, MA; Bourque, SL; Brien, SE; Davidge, ST; Whittingham, HA1

Other Studies

6 other study(ies) available for pd 145065 and ng-nitroarginine methyl ester

ArticleYear
Acute hypertension after nitric oxide synthase inhibition is mediated primarily by increased endothelin vasoconstriction.
    Journal of hypertension, 1996, Volume: 14, Issue:8

    Topics: Animals; Blood Pressure; Endothelins; Enzyme Inhibitors; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Vasoconstriction

1996
Vascular smooth muscle cell effect on endothelial cell endothelin-1 production.
    Journal of vascular surgery, 2000, Volume: 31, Issue:4

    Topics: Analysis of Variance; Animals; Aorta; Cattle; Cell Division; Cells, Cultured; Coculture Techniques; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oligopeptides; RNA; Transcription, Genetic

2000
Role of prostaglandin, endothelin and sympathetic nervous system on the L-NAME-induced pressor responses in spontaneously hypertensive rats.
    Brain research, 2003, Sep-05, Volume: 983, Issue:1-2

    Topics: Acetamides; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Chlorisondamine; Cyclooxygenase Inhibitors; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Ganglionic Blockers; Heart Rate; Indomethacin; Injections, Intraventricular; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oligopeptides; Prostaglandins; Rats; Rats, Inbred SHR; Sympathetic Nervous System

2003
Angiotensin II effect on hydraulic permeability: interaction with endothelin-1, nitric oxide, and platelet activating factor.
    The Journal of surgical research, 2006, Volume: 134, Issue:2

    Topics: Angiotensin II; Animals; Capillary Permeability; Drug Interactions; Endothelin A Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Female; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; Platelet Activating Factor; Rats; Rats, Sprague-Dawley

2006
Interactive modulation of renal myogenic autoregulation by nitric oxide and endothelin acting through ET-B receptors.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2007, Volume: 292, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Data Interpretation, Statistical; Endothelin B Receptor Antagonists; Endothelins; Enzyme Inhibitors; Homeostasis; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; Peptides, Cyclic; Rats; Rats, Wistar; Receptor, Endothelin B; Renal Circulation; Vascular Resistance

2007
Role of endothelin-1 in the hyper-responsiveness to nitrovasodilators following acute NOS inhibition.
    British journal of pharmacology, 2012, Volume: 165, Issue:6

    Topics: Animals; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oligopeptides; Rats; Rats, Sprague-Dawley; Vasodilator Agents

2012