Page last updated: 2024-09-03

pd 145065 and endothelin-1

pd 145065 has been researched along with endothelin-1 in 31 studies

Compound Research Comparison

Studies (pd 145065)	Trials (pd 145065)	Recent Studies (post-2010) (pd 145065)	Studies (endothelin-1)	Trials (endothelin-1)	Recent Studies (post-2010) (endothelin-1)
76	1	5	12,740	632	3,394

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	9 (29.03)	18.2507
2000's	18 (58.06)	29.6817
2010's	4 (12.90)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Atkinson, JB; Forman, MB; Holsinger, JP; Jackson, EK; Kawana, M; Murray, JJ; Quertermous, T; Vitola, JV	1
Fineman, JR; Hanley, FL; Hendricks-Munoz, KD; Petrossian, E; Rajasinghe, HA; Reddy, VM	1
Andriuoli, G; Calignano, A; Cirino, G; Pinto, A; Sorrentino, L	1
Allcock, GH; Warner, TD	1
Alexiou, K; Baumann, G; Dschietzig, T; Laule, M; Schrör, K; Stangl, K	1
Held, B; Pearson, HA; Pocock, JM	1
Forrest, CR; Lipa, JE; Neligan, PC; Pang, CY; Xu, H; Zhang, J	1
Fineman, JR; Hanley, FL; Hendricks-Munoz, K; Liddicoat, JR; McElhinney, DB; Rajasinghe, HA; Reddy, VM	1
Campbell, WB; Hanke, CJ; Rosolowsky, LJ	1
Bhargava, J; Di Luozzo, G; Powell, RJ	1
Cittadino, MH; Gordo, WM; Moreno, H; Tanus-Santos, JE; Udelsmann, A	1
Lee, BH; Rapoport, RM; Zuccarello, M	1
Curtis, LA; Holm, AS; Holmes, EP; Koch, CE; Moore, RM; Venugopal, CS	1
Calaghan, SC; White, E	1
Delamere, NA; Okafor, MC	1
Delamere, NA; Mukhopadhyay, P; Okafor, MC	1
Cachofeiro, V; Cediel, E; de las Heras, N; Lahera, V; Navarro-Cid, J; Sanz-Rosa, D; Vázquez-Cruz, B	1
Fandino, J; Rapoport, RM; Sherman, JD; Zuccarello, M	1
Delamere, NA; Okafor, M; Tamiya, S	1
Bauerová, K; Doherty, AM; Drímal, D; Drímal, J; Kettmann, V; Knezl, V; Stefek, M	1
D'Amico, M; Di Filippo, C; Getting, SJ; Lam, CW; Rossi, F	1
Bartoli, E; Bergamasco, L; Castello, L; Letizia, C; Sainaghi, PP	2
Chong, T; Ramirez, R; Victorino, GP	1
Eades, SC; Hosgood, G; Moore, RM; Stokes, AM; Venugopal, CS	1
Groenendijk, BC; Hierck, BP; Lindken, R; Nieuwstadt, FT; Poelmann, RE; Stekelenburg-de Vos, S; Ursem, NT; Vennemann, P; Westerweel, J; Wladimiroff, JW	1
Castro-Chaves, P; Fontes-Carvalho, R; Leite-Moreira, AF; Pimentel-Nunes, P; Pintalhao, M	1
Beimgraben, C; Delamere, NA; Mandal, A; Shahidullah, M	1
Adams, MA; Bourque, SL; Brien, SE; Davidge, ST; Whittingham, HA	1
Rapoport, RM; Yoon, S; Zuccarello, M	1
Hostetter, TA; Iliff, JJ; Jones, SM; Seo, JW; West, GA	1

Other Studies

31 other study(ies) available for pd 145065 and endothelin-1

Article	Year
Role of endothelin in a rabbit model of acute myocardial infarction: effects of receptor antagonists. Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:6 Topics: Animals; Azepines; Endothelin Receptor Antagonists; Endothelin-1; Heart; Hemodynamics; Indoles; Male; Myocardial Reperfusion Injury; Myocardium; Oligopeptides; Rabbits; Receptors, Endothelin; RNA, Messenger	1996
Post-cardiopulmonary bypass pulmonary hypertension in lambs with increased pulmonary blood flow. A role for endothelin 1. Circulation, 1997, Feb-18, Volume: 95, Issue:4 Topics: Animals; Blood Pressure; Cardiopulmonary Bypass; Child; Endothelin-1; Female; Fetus; Heart Rate; Hemodynamics; Humans; Hypertension, Pulmonary; Oligopeptides; Postoperative Complications; Pregnancy; Pulmonary Artery; Pulmonary Circulation; Sheep; Vascular Resistance	1997
Fluoroaluminate induces rapid release of endothelin-1 in the isolated perfused arterial and venous vessels of the rat mesentery. General pharmacology, 1997, Volume: 28, Issue:3 Topics: Aluminum; Animals; Azepines; Endothelin Receptor Antagonists; Endothelin-1; Fluorine; Indoles; Male; Mesenteric Arteries; Mesenteric Veins; Oligopeptides; Perfusion; Rats; Rats, Wistar; Type C Phospholipases	1997
Activation of ET(A) receptors is partially responsible for the rapid increase in haematocrit induced by bacterial lipopolysaccharide in the rat. Life sciences, 1997, Volume: 60, Issue:19 Topics: Animals; Azepines; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Hematocrit; Indoles; Lipopolysaccharides; Male; Oligopeptides; Rats; Rats, Wistar; Receptor, Endothelin A; Receptors, Endothelin	1997
Coronary constriction and consequent cardiodepression in pulmonary embolism are mediated by pulmonary big endothelin and enhanced in early endothelial dysfunction. Critical care medicine, 1998, Volume: 26, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arteriosclerosis; Aspartic Acid Endopeptidases; Atrasentan; Coronary Circulation; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Endothelins; Endothelium, Vascular; Glycopeptides; In Vitro Techniques; Male; Metalloendopeptidases; Myocardial Contraction; Oligopeptides; Peptides, Cyclic; Protein Precursors; Pulmonary Embolism; Pyrrolidines; Rabbits; Thromboxane B2; Vasoconstriction	1998
Endothelin-1 inhibits voltage-sensitive Ca2+ channels in cultured rat cerebellar granule neurones via the ET-A receptor. Pflugers Archiv : European journal of physiology, 1998, Volume: 436, Issue:5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Signaling; Cerebellum; Dose-Response Relationship, Drug; Endothelin-1; Male; Nerve Tissue Proteins; Neurons; Oligopeptides; Patch-Clamp Techniques; Peptides, Cyclic; Potassium; Potassium Chloride; Rats; Rats, Wistar; Receptor, Endothelin A; Receptors, Cholinergic; Receptors, Endothelin; Second Messenger Systems; Viper Venoms	1998
Role and mechanism of endothelin-B receptors in mediating ET-1-induced vasoconstriction in pig skin. The American journal of physiology, 1998, Volume: 275, Issue:4 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Amino Acid Sequence; Animals; Antihypertensive Agents; Bosentan; Endothelin-1; Endothelins; Infusions, Intra-Arterial; Molecular Sequence Data; Norepinephrine; Oligopeptides; Peptide Fragments; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Skin; Sulfonamides; Surgical Flaps; Swine; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms	1998
Role of the endothelium in placental dysfunction after fetal cardiac bypass. The Journal of thoracic and cardiovascular surgery, 1999, Volume: 117, Issue:2 Topics: Acetylcholine; Analysis of Variance; Animals; Cardiac Surgical Procedures; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Female; Fetal Heart; Hemodynamics; Nitroprusside; Oligopeptides; Placenta; Placenta Diseases; Postoperative Complications; Pregnancy; Sheep; Vasodilator Agents	1999
Adrenal capillary endothelial cells stimulate aldosterone release through a protein that is distinct from endothelin. Endocrinology, 1999, Volume: 140, Issue:10 Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; Animals; Bradykinin; Capillaries; Cattle; Coculture Techniques; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Hormone Antagonists; Oligopeptides; Osmolar Concentration; Pronase; Receptor, Endothelin B; Steroids; Time Factors; Zona Fasciculata; Zona Glomerulosa	1999
Vascular smooth muscle cell effect on endothelial cell endothelin-1 production. Journal of vascular surgery, 2000, Volume: 31, Issue:4 Topics: Analysis of Variance; Animals; Aorta; Cattle; Cell Division; Cells, Cultured; Coculture Techniques; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Enzyme Inhibitors; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oligopeptides; RNA; Transcription, Genetic	2000
Nonselective endothelin-receptor antagonism attenuates hemodynamic changes after massive pulmonary air embolism in dogs. Chest, 2000, Volume: 118, Issue:1 Topics: Animals; Dogs; Embolism, Air; Endothelin Receptor Antagonists; Endothelin-1; Female; Hemodynamics; Male; Oligopeptides; Prospective Studies; Pulmonary Embolism; Thromboxanes	2000
Hypocapnic constriction in rabbit basilar artery in vitro: triggering by N(G)-monomethyl-L-arginine monoacetate and dependence on endothelin-1 and alkalosis. European journal of pharmacology, 2000, Aug-04, Volume: 401, Issue:2 Topics: Acetylcholine; Alkalies; Alkalosis; Animals; Basilar Artery; Carbon Dioxide; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Hypocapnia; In Vitro Techniques; Male; Oligopeptides; omega-N-Methylarginine; Papaverine; Piperidines; Rabbits; Receptor, Endothelin A; Receptor, Endothelin B; Solutions; Vasoconstriction; Vasodilation; Vasodilator Agents	2000
In vitro pharmacologic effect of two endothelin-1 antagonists on equine colonic arteries and veins. American journal of veterinary research, 2001, Volume: 62, Issue:2 Topics: Animals; Arteries; Colon; Dose-Response Relationship, Drug; Drug Synergism; Endothelin-1; Horses; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Vasoconstriction; Veins	2001
Contribution of angiotensin II, endothelin 1 and the endothelium to the slow inotropic response to stretch in ferret papillary muscle. Pflugers Archiv : European journal of physiology, 2001, Volume: 441, Issue:4 Topics: Angiotensin II; Animals; Endothelin-1; Endothelium; Female; Ferrets; Kinetics; Losartan; Male; Muscle Spindles; Myocardial Contraction; Octoxynol; Oligopeptides; Papillary Muscles; Peptides, Cyclic; Saralasin	2001
The inhibitory influence of endothelin on active sodium-potassium transport in porcine lens. Investigative ophthalmology & visual science, 2001, Volume: 42, Issue:5 Topics: Animals; Biological Transport, Active; Colforsin; Cyclic AMP; Endothelin-1; Enzyme Inhibitors; Genistein; Lens, Crystalline; Oligopeptides; Potassium; Receptors, Endothelin; Rubidium Radioisotopes; Sodium; Sodium-Potassium-Exchanging ATPase; Swine	2001
Studies on endothelin release and Na,K transport in porcine lens. Investigative ophthalmology & visual science, 2002, Volume: 43, Issue:3 Topics: Animals; Calcimycin; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Insulin; Ion Transport; Lens, Crystalline; Oligopeptides; Potassium; Receptors, Endothelin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Sodium-Potassium-Exchanging ATPase; Swine; Thrombin; Up-Regulation	2002
Role of endothelin-1 and thromboxane A2 in renal vasoconstriction induced by angiotensin II in diabetes and hypertension. Kidney international. Supplement, 2002, Issue:82 Topics: Angiotensin II; Animals; Blood Pressure; Bridged Bicyclo Compounds, Heterocyclic; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Hypertension; Kidney; Male; Oligopeptides; Oxazoles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Endothelin; Receptors, Thromboxane A2, Prostaglandin H2; Renal Circulation; Thromboxane A2; Vascular Resistance; Vasoconstriction	2002
Cocaine-induced endothelin-1-dependent spasm in rabbit basilar artery in vivo. Journal of cardiovascular pharmacology, 2003, Volume: 41, Issue:2 Topics: Animals; Basilar Artery; Cocaine; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Male; Oligopeptides; Rabbits; Receptor, Endothelin A; Receptors, Endothelin; Vasoconstriction	2003
Sodium-calcium exchange influences the response to endothelin-1 in lens epithelium. Cell calcium, 2003, Volume: 34, Issue:3 Topics: Animals; Bepridil; Blotting, Western; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Endothelin A Receptor Antagonists; Endothelin-1; Epithelial Cells; Fura-2; Immunohistochemistry; Indoles; Ionomycin; Lens, Crystalline; Microscopy, Fluorescence; Oligopeptides; Ouabain; Receptor, Endothelin A; Sodium; Sodium-Calcium Exchanger; Swine	2003
Cardiac effects of endothelin-1 (ET-1) and related C terminal peptide fragment: increased inotropy or contribution to heart failure? Physiological research, 2003, Volume: 52, Issue:6 Topics: Amino Acid Sequence; Animals; Coronary Circulation; Dioxoles; Endothelin-1; Endothelins; Heart; Heart Failure; Heart Rate; Humans; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Oligopeptides; Peptide Fragments; Perfusion; Piperidines; Rats; Rats, Wistar; Ventricular Function, Left; Ventricular Pressure	2003
Investigation into the potential anti-inflammatory effects of endothelin antagonists in a murine model of experimental monosodium urate peritonitis. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 310, Issue:1 Topics: Animals; Azepines; Chemokines; Endothelin Receptor Antagonists; Endothelin-1; Indoles; Interleukin-1; Mice; Neutrophils; Oligopeptides; Peritonitis; Piperidines; Platelet Activating Factor; Time Factors; Uric Acid	2004
Pathways of glomerular toxicity of cyclosporine-A: an "in vitro" study. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2005, Volume: 56, Issue:4 Topics: Angiotensin I; Angiotensin II; Animals; Cyclosporine; Endothelin-1; Female; Kidney Glomerulus; Oligopeptides; Organ Culture Techniques; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Swine; Time Factors	2005
Angiotensin II effect on hydraulic permeability: interaction with endothelin-1, nitric oxide, and platelet activating factor. The Journal of surgical research, 2006, Volume: 134, Issue:2 Topics: Angiotensin II; Animals; Capillary Permeability; Drug Interactions; Endothelin A Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Female; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; Platelet Activating Factor; Rats; Rats, Sprague-Dawley	2006
Comparison of 2 endothelin-receptor antagonists on in vitro responses of equine palmar digital arterial and venous rings to endothelin-1. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2006, Volume: 70, Issue:3 Topics: Animals; Arteries; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Horses; In Vitro Techniques; Muscle, Smooth, Vascular; Oligopeptides; Toes; Veins	2006
The endothelin-1 pathway and the development of cardiovascular defects in the haemodynamically challenged chicken embryo. Journal of vascular research, 2008, Volume: 45, Issue:1 Topics: Animals; Aspartic Acid Endopeptidases; Blood Flow Velocity; Cardiac Output; Cardiovascular Abnormalities; Cells, Cultured; Chick Embryo; Echocardiography; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Gene Expression Regulation, Developmental; Heart; Heart Rate; Hemodynamics; Laser-Doppler Flowmetry; Ligation; Metalloendopeptidases; Myocardium; Oligopeptides; Peptides, Cyclic; Piperidines; Receptors, Endothelin; RNA, Messenger; Signal Transduction; Time Factors; Veins; Ventricular Function; Yolk Sac	2008
In vitro effect of cyclosporine-A on angiotensins secretion by glomerular cells. Nephrology (Carlton, Vic.), 2008, Volume: 13, Issue:4 Topics: Angiotensin I; Angiotensin II; Animals; Cyclosporine; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Female; Immunosuppressive Agents; Kidney Glomerulus; Oligopeptides; Peptides, Cyclic; Piperidines; Receptor, Endothelin A; Receptor, Endothelin B; Swine; Time Factors; Tissue Culture Techniques; Up-Regulation	2008
Angiotensin II-induced increase in myocardial distensibility and its modulation by the endocardial endothelium in the rabbit heart. Experimental physiology, 2009, Volume: 94, Issue:6 Topics: Acetophenones; Angiotensin II; Animals; Diastole; Dose-Response Relationship, Drug; Endocardium; Endothelin Receptor Antagonists; Endothelin-1; Endothelium; Enzyme Inhibitors; In Vitro Techniques; Male; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oligopeptides; Papillary Muscles; Peptides, Cyclic; Rabbits; Receptors, Endothelin	2009
The effect of endothelin-1 on Src-family tyrosine kinases and Na,K-ATPase activity in porcine lens epithelium. Journal of cellular physiology, 2011, Volume: 226, Issue:10 Topics: Adenosine Triphosphate; Animals; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Epithelium; Lens, Crystalline; Oligopeptides; Organ Culture Techniques; Proto-Oncogene Proteins c-fyn; Signal Transduction; Sodium-Potassium-Exchanging ATPase; src-Family Kinases; Sus scrofa; Uridine Triphosphate	2011
Role of endothelin-1 in the hyper-responsiveness to nitrovasodilators following acute NOS inhibition. British journal of pharmacology, 2012, Volume: 165, Issue:6 Topics: Animals; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroprusside; Oligopeptides; Rats; Rats, Sprague-Dawley; Vasodilator Agents	2012
Cocaine constriction of rat basilar artery in situ: roles of nitric oxide and endothelin-1. Pharmacology, 2014, Volume: 93, Issue:3-4 Topics: Animals; Basilar Artery; Capsaicin; Cocaine; Dose-Response Relationship, Drug; Endothelin-1; Male; Nitric Oxide; Nitric Oxide Synthase; Oligopeptides; Rats; Rats, Sprague-Dawley; Vasoconstriction	2014
Methamphetamine induces the release of endothelin. Journal of neuroscience research, 2016, Volume: 94, Issue:2 Topics: Analysis of Variance; Animals; Arteries; Brain; Cell Line, Transformed; Cell Survival; Central Nervous System Stimulants; Dose-Response Relationship, Drug; Endothelin-1; Endothelium; Enzyme-Linked Immunosorbent Assay; Methamphetamine; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type III; Oligopeptides; RNA, Messenger; Time Factors; Vasoconstriction	2016