Page last updated: 2024-09-03

pd 142893 and endothelin-1

pd 142893 has been researched along with endothelin-1 in 32 studies

Compound Research Comparison

Studies (pd 142893)	Trials (pd 142893)	Recent Studies (post-2010) (pd 142893)	Studies (endothelin-1)	Trials (endothelin-1)	Recent Studies (post-2010) (endothelin-1)
64	0	3	12,740	632	3,394

Research

Studies (32)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	12 (37.50)	18.2507
2000's	16 (50.00)	29.6817
2010's	4 (12.50)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brunner, F; Doherty, AM	1
Cervar, M; Desoye, G; Kainer, F; Puerstner, P	1
Grafov, MA; Lapshin, AV; Manukhina, EB; Medvedev, OS; Medvedeva, NA; Rubina, AIu	1
Chevillard, C; Hamroun, D; Laliberté, F; Laliberté, MF; Launay, JM; Mathieu, MN; Nonotte, I; Vittet, D	1
de Wit, D; Kimura, S; Masaki, T; Masuda, Y; Mizuguchi, T; Moroi, K; Nishiyama, M; Saito, T; Tanaka, H; Yanagisawa, M	1
Cody, WL; Doherty, AM; Haleen, SJ; He, JX; Reily, MD; Reyner, EL; Stewart, BH; Walker, DM	1
Acland, RD; Anderson, G; Barker, J; Wang, WZ	1
Brunner, F	1
Dai, SM; Miao, CY; Shan, ZZ; Su, DF; Yin, M	1
Brunner, F; Kukovetz, WR; Leonhard, B; Mayer, B	1
Benigni, A; Bertani, T; Brena, C; Bruzzi, I; Colosio, V; Remuzzi, G	1
Bodelsson, G; Laursen, M; Stjernquist, M	1
Costa, S; Monti, LD; Phan, CV; Piatti, PM; Pontiroli, AE; Pozza, G; Sandoli, EP; Valsecchi, G	1
Goto, K	1
Davydova, MP; Grafov, MA; Medvedeva, NA; Tolordava, IA; Volkov, VN	1
Grafov, MA; Kalenikova, EI; Zaretskaia, MV; Zaretsky, DV	1
Curtis, LA; Holm, AS; Holmes, EP; Koch, CE; Moore, RM; Venugopal, CS	1
Damon, DH	1
Hendry, BM; James, AF; Ramsey, JE; Reynolds, AM; Shattock, MJ	1
Asham, E; Boulos, PB; Burnstock, G; Fredericks, S; Loizidou, M; Miller, K; Shankar, A; Taylor, I	1
Gardner, A; Hoang, D; Macarthur, H; Westfall, TC	1
de Champlain, J; Lamontagne, D; Millette, E	1
Bruch, D; Kittur, DS; Kittur, S; Ondocin, P; Shah, G; Wilasrusmee, C; Wilasrusmee, S	1
Desai, D; He, S; Krishnamoorthy, RR; Prasanna, G; Yorio, T	1
Achard, JM; Faure, S; Javellaud, J; Oudart, N	1
Clark, AD; Eringa, EC; Sipkema, P; Stehouwer, CD; van Nieuw Amerongen, GP; Walburg, K; Westerhof, N	1
Eades, SC; Hosgood, G; Moore, RM; Stokes, AM; Venugopal, CS	1
Eringa, EC; Roos, MH; Sipkema, P; Stehouwer, CD; Westerhof, N	1
Meoli, DF; White, RJ	1
Aguirre, A; Dupree, J; Gadea, A; Gallo, V; Hammond, TR; Kerninon, C; Nait-Oumesmar, B	1
Chen, W; Li, T; Liu, LM; Zhang, ZS	1
Cao, Z; Jia, Y; Luo, X; Tian, M; Wang, T; Xiao, Y; Xue, J; Zhang, Y; Zhu, B	1

Reviews

1 review(s) available for pd 142893 and endothelin-1

Article	Year
[Endothelin receptors]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 2000, Volume: 45, Issue:6 Suppl Topics: Animals; Cardiovascular Diseases; Drug Design; Endothelin Receptor Antagonists; Endothelin-1; GTP-Binding Proteins; Humans; Oligopeptides; Peptides, Cyclic; Piperidines; Receptors, Endothelin; Signal Transduction	2000

Other Studies

31 other study(ies) available for pd 142893 and endothelin-1

Article	Year
Role of ET(B) receptors in local clearance of endothelin-1 in rat heart: studies with the antagonists PD 155080 and BQ-788. FEBS letters, 1996, Nov-04, Volume: 396, Issue:2-3 Topics: Animals; Coronary Vessels; Dioxoles; Endothelin Receptor Antagonists; Endothelin-1; Heart Rate; In Vitro Techniques; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Oligopeptides; Piperidines; Rats; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Vascular Resistance; Ventricular Function, Left	1996
Endothelin-1 stimulates the proliferation and invasion of first trimester trophoblastic cells in vitro--a possible role in the etiology of pre-eclampsia? Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 1996, Volume: 44, Issue:8 Topics: Cell Division; Cell Survival; Cells, Cultured; Chorionic Gonadotropin; Eclampsia; Endothelin-1; Female; Humans; Oligopeptides; Pregnancy; Pregnancy Trimester, First; Trophoblasts	1996
[Endothelin-1 modulates acetylcholine-induces relaxation of isolated rat aorta]. Doklady Akademii nauk, 1996, Volume: 351, Issue:1 Topics: Acetylcholine; Animals; Aorta; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; In Vitro Techniques; Male; Oligopeptides; Rats; Rats, Wistar; Vasodilation	1996
Endothelin expression in human megakaryoblastic leukemia cell lines and normal platelet precursors. Regulatory peptides, 1997, Jan-29, Volume: 68, Issue:2 Topics: Blood Platelets; Blotting, Southern; Cell Division; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression; Hematopoietic Stem Cells; Humans; Immunohistochemistry; Leukemia, Megakaryoblastic, Acute; Megakaryocytes; Oligopeptides; Polymerase Chain Reaction; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; RNA, Messenger; Thrombin; Tumor Cells, Cultured; Viper Venoms	1997
Analysis of two pharmacologically predicted endothelin B receptor subtypes by using the endothelin B receptor gene knockout mouse. British journal of pharmacology, 1997, Volume: 120, Issue:8 Topics: Animals; Aorta; Endothelin-1; Gastric Fundus; In Vitro Techniques; Mice; Mice, Knockout; Muscle Contraction; Muscle Relaxation; Oligopeptides; Peptides, Cyclic; Phenylephrine; Receptor, Endothelin B; Receptors, Endothelin	1997
Design of a potent combined pseudopeptide endothelin-A/endothelin-B receptor antagonist, Ac-DBhg16-Leu-Asp-Ile-[NMe]Ile-Trp21 (PD 156252): examination of its pharmacokinetic and spectral properties. Journal of medicinal chemistry, 1997, Jul-04, Volume: 40, Issue:14 Topics: Amino Acid Sequence; Animals; Drug Design; Endothelin Receptor Antagonists; Endothelin-1; Femoral Artery; Humans; In Vitro Techniques; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Protein Conformation; Pulmonary Artery; Rabbits; Rats; Receptor, Endothelin A; Receptor, Endothelin B; Renal Circulation; Structure-Activity Relationship; Tumor Cells, Cultured	1997
Endothelin-1 does not contribute to ischemia/reperfusion-induced vasoconstriction in skeletal muscle. Journal of reconstructive microsurgery, 1997, Volume: 13, Issue:6 Topics: Analysis of Variance; Animals; Arteries; Endothelin-1; Humans; Male; Muscle, Skeletal; Oligopeptides; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Vasoconstriction	1997
Interaction of nitric oxide and endothelin-1 in ischemia/reperfusion injury of rat heart. Journal of molecular and cellular cardiology, 1997, Volume: 29, Issue:9 Topics: Acetylcholine; Animals; Cyclic AMP; Endothelin-1; Enzyme Inhibitors; Exudates and Transudates; Heart Rate; In Vitro Techniques; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oligopeptides; Penicillamine; Perfusion; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine	1997
Hemodynamic responses to endothelin-1 and endothelin antagonists microinjected into the nucleus tractus solitarius in rats. Journal of cardiovascular pharmacology, 1997, Volume: 30, Issue:4 Topics: Animals; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Heart Rate; Hexamethonium; Male; Microinjections; Oligopeptides; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Solitary Nucleus	1997
Role of endothelin, nitric oxide and L-arginine release in ischaemia/reperfusion injury of rat heart. Cardiovascular research, 1997, Volume: 36, Issue:1 Topics: Analysis of Variance; Animals; Arginine; Chromatography, High Pressure Liquid; Cyclic GMP; Endothelin Receptor Antagonists; Endothelin-1; L-Lactate Dehydrogenase; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oligopeptides; Penicillamine; Perfusion; Rats; Rats, Sprague-Dawley; S-Nitroso-N-Acetylpenicillamine; Vasodilator Agents	1997
Unselective inhibition of endothelin receptors reduces renal dysfunction in experimental diabetes. Diabetes, 1998, Volume: 47, Issue:3 Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cohort Studies; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Follow-Up Studies; In Situ Hybridization; Kidney; Lisinopril; Male; Oligopeptides; Pilot Projects; Proteinuria; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors	1998
Atypical receptors mediate the response to endothelin-1 and sarafotoxin S6b in the human umbilical artery. European journal of pharmacology, 1998, Dec-04, Volume: 362, Issue:2-3 Topics: Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Humans; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Piperidines; Receptor, Endothelin B; Umbilical Arteries; Vasoconstriction; Vasoconstrictor Agents; Viper Venoms	1998
Effects of endothelin-1 and nitric oxide on glucokinase activity in isolated rat hepatocytes. Metabolism: clinical and experimental, 2000, Volume: 49, Issue:1 Topics: Animals; Arginine; Cells, Cultured; Cyclic GMP; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Glucokinase; Glucose; Glycogen; Kinetics; Liver; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Oligopeptides; Piperidines; Rats; Rats, Sprague-Dawley	2000
Altered endothelin-dependent regulation of blood pressure and vascular tone in stress-sensitive august rats. Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:5 Suppl 1 Topics: Animals; Blood Pressure; Endothelin-1; Heart Rate; Male; Oligopeptides; Rats; Stress, Physiological; Vasoconstriction	2000
Endothelin antagonism does not affect adrenal catecholamine secretion and system haemodynamics during acute stress in Wistar rats. Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:5 Suppl 1 Topics: Acute Disease; Animals; Catecholamines; Endothelin Receptor Antagonists; Endothelin-1; Hemodynamics; Male; Oligopeptides; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; Stress, Physiological	2000
In vitro pharmacologic effect of two endothelin-1 antagonists on equine colonic arteries and veins. American journal of veterinary research, 2001, Volume: 62, Issue:2 Topics: Animals; Arteries; Colon; Dose-Response Relationship, Drug; Drug Synergism; Endothelin-1; Horses; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Oligopeptides; Vasoconstriction; Veins	2001
NGF-independent survival of postganglionic sympathetic neurons in neuronal-vascular smooth muscle cocultures. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 280, Issue:4 Topics: Animals; Animals, Newborn; Cell Division; Cell Survival; Coculture Techniques; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Male; Nerve Growth Factor; Neurons; Oligopeptides; Rats; Rats, Sprague-Dawley; Receptors, Endothelin; Superior Cervical Ganglion; Time Factors; Tyrosine 3-Monooxygenase	2001
Effects of endothelin-1 on K(+) currents from rat ventricular myocytes. Biochemical and biophysical research communications, 2001, Jun-22, Volume: 284, Issue:4 Topics: Animals; Cells, Cultured; Endothelin-1; Heart; Heart Ventricles; Male; Membrane Potentials; Myocardium; Oligopeptides; Patch-Clamp Techniques; Potassium; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Wistar	2001
Increased endothelin-1 in colorectal cancer and reduction of tumour growth by ET(A) receptor antagonism. British journal of cancer, 2001, Nov-30, Volume: 85, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Animals; Colon; Colorectal Neoplasms; Endothelin Receptor Antagonists; Endothelin-1; Female; Humans; Immunohistochemistry; Liver Neoplasms; Male; Middle Aged; Neoplasm Transplantation; Neoplasms, Experimental; Oligopeptides; Peptides, Cyclic; Pyrrolidines; Rats; Receptor, Endothelin A; Receptor, Endothelin B	2001
Endothelin-induced modulation of neuropeptide Y and norepinephrine release from the rat mesenteric bed. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:4 Topics: Animals; Antihypertensive Agents; Electric Stimulation; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Male; Mesenteric Arteries; Neuropeptide Y; Norepinephrine; Oligopeptides; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Vasoconstrictor Agents; Viper Venoms	2002
Contribution of endogenous endothelin in the enhanced coronary constriction in DOCA-salt hypertensive rats. Journal of hypertension, 2003, Volume: 21, Issue:1 Topics: Angiotensin II; Animals; Coronary Circulation; Desoxycorticosterone; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Heart; Hypertension; In Vitro Techniques; Male; Nephrectomy; Oligopeptides; Propionates; Pyrimidines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Chloride; Vasoconstriction; Vasoconstrictor Agents; Vasopressins	2003
Amelioration of cyclosporin A effect on microvasculature by endothelin inhibitor. Surgery, 2003, Volume: 134, Issue:2 Topics: Animals; Antibodies; Capillaries; Cyclosporine; Dose-Response Relationship, Drug; Endothelin-1; Endothelium, Vascular; Kidney; Mice; Mice, Inbred C3H; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Physiologic; Oligopeptides; Survival Analysis	2003
Hypoxia augments TNF-alpha-mediated endothelin-1 release and cell proliferation in human optic nerve head astrocytes. Biochemical and biophysical research communications, 2004, Jun-04, Volume: 318, Issue:3 Topics: Aged; Aged, 80 and over; Aspartic Acid Endopeptidases; Astrocytes; Butadienes; Cell Division; Cell Hypoxia; Cell Line, Tumor; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-Converting Enzymes; Enzyme Inhibitors; Glycopeptides; Humans; Metalloendopeptidases; Mitogen-Activated Protein Kinases; Nitriles; Oligopeptides; Optic Disk; Protease Inhibitors; Tumor Necrosis Factor-alpha	2004
Vasoconstrictive effect of angiotensin IV in isolated rat basilar artery independent of AT1 and AT2 receptors. Journal of vascular research, 2006, Volume: 43, Issue:1 Topics: Angiotensin II; Animals; Basilar Artery; Drug Interactions; Endothelin-1; Endothelium, Vascular; Gene Expression; In Vitro Techniques; Male; Oligopeptides; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasoconstriction; Vasoconstrictor Agents	2006
Physiological concentrations of insulin induce endothelin-dependent vasoconstriction of skeletal muscle resistance arteries in the presence of tumor necrosis factor-alpha dependence on c-Jun N-terminal kinase. Arteriosclerosis, thrombosis, and vascular biology, 2006, Volume: 26, Issue:2 Topics: Acetylcholine; Animals; Arteries; Endothelin-1; Endothelium, Vascular; Hypoglycemic Agents; Insulin; JNK Mitogen-Activated Protein Kinases; Muscle, Skeletal; Oligopeptides; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Vascular Resistance; Vasoconstriction; Vasodilation; Vasodilator Agents	2006
Comparison of 2 endothelin-receptor antagonists on in vitro responses of equine palmar digital arterial and venous rings to endothelin-1. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2006, Volume: 70, Issue:3 Topics: Animals; Arteries; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Horses; In Vitro Techniques; Muscle, Smooth, Vascular; Oligopeptides; Toes; Veins	2006
Selective resistance to vasoactive effects of insulin in muscle resistance arteries of obese Zucker (fa/fa) rats. American journal of physiology. Endocrinology and metabolism, 2007, Volume: 293, Issue:5 Topics: Animals; Blotting, Western; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; In Vitro Techniques; Insulin; Insulin Resistance; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type III; Nitroarginine; Obesity; Oligopeptides; Oncogene Protein v-akt; Rats; Rats, Zucker; Receptors, Endothelin; Vasoconstriction; Vasodilation	2007
Endothelin-1 induces pulmonary but not aortic smooth muscle cell migration by activating ERK1/2 MAP kinase. Canadian journal of physiology and pharmacology, 2010, Volume: 88, Issue:8 Topics: Animals; Antihypertensive Agents; Aorta; Becaplermin; Cell Line; Cell Movement; Cells, Cultured; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Humans; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Oligopeptides; Peptides, Cyclic; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Signal Transduction; Tunica Media	2010
Astrocyte-derived endothelin-1 inhibits remyelination through notch activation. Neuron, 2014, Feb-05, Volume: 81, Issue:3 Topics: Animals; Astrocytes; Calcium-Binding Proteins; Cell Count; Cell Differentiation; Demyelinating Diseases; Disease Models, Animal; Drug Delivery Systems; Endothelin-1; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Green Fluorescent Proteins; Intercellular Signaling Peptides and Proteins; Jagged-1 Protein; Lipopolysaccharides; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oligopeptides; Platelet Endothelial Cell Adhesion Molecule-1; Receptors, Notch; Serrate-Jagged Proteins; Stem Cells	2014
Organ-specific changes in vascular reactivity and roles of inducible nitric oxide synthase and endothelin-1 in a rabbit endotoxic shock model. The journal of trauma and acute care surgery, 2018, Volume: 85, Issue:4 Topics: Acetylcholine; Animals; Celiac Artery; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin-1; Enzyme Inhibitors; Female; Guanidines; Lactic Acid; Lipopolysaccharides; Male; Mesenteric Artery, Superior; Nitric Oxide Synthase Type II; Norepinephrine; Oligopeptides; Rabbits; Renal Artery; RNA, Messenger; Shock, Septic; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents	2018
The Expression of BNP, ET-1, and TGF-β1 in Myocardium of Rats with Ventricular Arrhythmias. International journal of molecular sciences, 2019, Nov-21, Volume: 20, Issue:23 Topics: Animals; Arrhythmias, Cardiac; Benzamides; Death, Sudden, Cardiac; Dioxoles; Endothelin Receptor Antagonists; Endothelin-1; Gene Expression; Male; Myocardium; Natriuretic Peptide, Brain; Oligopeptides; Rats, Sprague-Dawley; Receptors, Endothelin; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta1	2019