pd 135158 has been researched along with sincalide in 14 studies
| Studies (pd 135158) | Trials (pd 135158) | Recent Studies (post-2010) (pd 135158) | Studies (sincalide) | Trials (sincalide) | Recent Studies (post-2010) (sincalide) |
|---|---|---|---|---|---|
| 51 | 0 | 0 | 4,015 | 72 | 533 |
| Protein | Taxonomy | pd 135158 (IC50) | sincalide (IC50) |
|---|---|---|---|
| Cholecystokinin receptor type A | Rattus norvegicus (Norway rat) | 0.0006 | |
| Cholecystokinin receptor type A | Homo sapiens (human) | 0.0006 | |
| Gastrin/cholecystokinin type B receptor | Homo sapiens (human) | 0.001 | |
| Gastrin/cholecystokinin type B receptor | Mus musculus (house mouse) | 0.0008 | |
| Cholecystokinin receptor type A | Cavia porcellus (domestic guinea pig) | 0.0004 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (71.43) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Henklein, P; Zippel, U | 1 |
| Chen, D; Ding, XQ; Håkanson, R | 1 |
| Fölsch, UR; Höcker, M; Hughes, J; Schmidt, WE | 1 |
| Balschun, D; Reymann, KG | 1 |
| Wang, HL; Wu, T | 2 |
| Fuxe, K; Hernandez-Gómez, AM; Méndez-Franco, J; Pérez de la Mora, M | 1 |
| Choi, YS; Kim, YH; Song, DK; Suh, HW | 1 |
| Colombo, S; Letari, O; Makovec, F; Mennuni, L; Revel, L | 1 |
| Acosta, GB | 1 |
| Blackburn-Munro, G; Dickinson, T; Fleetwood-Walker, SM | 1 |
| Guimarães, FS; Netto, CF | 1 |
| Davidowa, H; Plagemann, A; Zippel, U | 1 |
| Hara, I; Hayashi, H; Kagawa, K; Kirisawa, R; Onaga, T; Sugita, A; Wakaiki, R | 1 |
14 other study(ies) available for pd 135158 and sincalide
| Article | Year |
|---|---|
Effects of two newly synthetized cholecystokinin tetrapeptides on the activity of single hippocampal and thalamic neurons.
Topics: Animals; Anti-Anxiety Agents; Cholecystokinin; Electrophysiology; Hippocampus; Indoles; Male; Meglumine; Neurons; Neuropeptides; Rats; Rats, Wistar; Receptors, Cholecystokinin; Sincalide; Thalamus | 1995 |
Cholecystokinin-B receptor ligands of the dipeptoid series act as agonists on rat stomach histidine decarboxylase.
Topics: Animals; Benzodiazepinones; Devazepide; Enzyme Activation; Gastrins; Histidine Decarboxylase; Indoles; Ligands; Male; Meglumine; Phenethylamines; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sincalide; Stomach | 1995 |
PD 135158, a CCKB/gastrin receptor antagonist, stimulates rat pancreatic enzyme secretion as a CCKA receptor agonist.
Topics: Animals; Anti-Anxiety Agents; Cholecystokinin; Drug Interactions; Indoles; Lipase; Meglumine; Pancreas; Proglumide; Rats; Sincalide | 1993 |
Cholecystokinin (CCK-8S) prolongs 'unsaturated' theta-pulse induced long-term potentiation in rat hippocampal CA1 in vitro.
Topics: Animals; Anti-Anxiety Agents; Evoked Potentials; Hippocampus; Indoles; Long-Term Potentiation; Male; Meglumine; Pyramidal Cells; Rats; Rats, Wistar; Sincalide; Theta Rhythm | 1994 |
CCK-8 excites substantia nigra dopaminergic neurons by increasing a cationic conductance.
Topics: Animals; Cations; Dopamine; Dose-Response Relationship, Drug; Electrophysiology; Indoles; Meglumine; Neurons; Rats; Rats, Sprague-Dawley; Sincalide; Sodium; Substantia Nigra; Tetragastrin | 1994 |
Cholecystokinin-8 increases K(+)-evoked [3H] gamma-aminobutyric acid release in slices from various brain areas.
Topics: Animals; Benzodiazepinones; beta-Alanine; Brain; Calcium; Devazepide; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Indoles; Male; Meglumine; Phenylurea Compounds; Potassium; Rats; Rats, Wistar; Receptors, Cholecystokinin; Sincalide | 1993 |
Involvement of different subtypes of cholecystokinin receptors in opioid antinociception in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Animals; beta-Endorphin; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Indoles; Injections, Intraventricular; Male; Meglumine; Mice; Mice, Inbred ICR; Morphine; Narcotics; Pain Measurement; Proglumide; Pyrrolidines; Receptors, Cholecystokinin; Sincalide | 1995 |
Cytosolic Ca2+ evaluation in rabbit parietal cells: a novel method to screen gastrin receptor antagonists.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Benzodiazepinones; Calcium; Devazepide; Dose-Response Relationship, Drug; Fura-2; Gastrins; Hormone Antagonists; Humans; Indoles; Male; Meglumine; Parietal Cells, Gastric; Phenylurea Compounds; Rabbits; Receptors, Cholecystokinin; Sincalide | 1996 |
The excitatory effect of cholecystokinin on rat neostriatal neurons: ionic and molecular mechanisms.
Topics: Action Potentials; Animals; Calcium; Chelating Agents; Cholecystokinin; Egtazic Acid; Evoked Potentials; GTP-Binding Proteins; Heparin; Immunohistochemistry; In Vitro Techniques; Indoles; Ion Channels; Meglumine; Neostriatum; Neural Conduction; Neurons, Afferent; Patch-Clamp Techniques; Pertussis Toxin; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Cholecystokinin; Sincalide; Tetragastrin; Virulence Factors, Bordetella | 1996 |
Administration of cholecystokinin sulphated octapeptide (CCK-8S) induces changes on rat amino acid tissue levels and on a behavioral test for anxiety.
Topics: Alanine; Amino Acids; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Brain; Cerebral Cortex; Corpus Striatum; gamma-Aminobutyric Acid; Glutamic Acid; Glycine; Hippocampus; Hypothalamus; Indoles; Lighting; Male; Meglumine; Neurotransmitter Agents; Olfactory Bulb; Rats; Rats, Wistar; Sincalide; Taurine | 1998 |
Non-opioid actions of lamotrigine within the rat dorsal horn after inflammation and neuropathic nerve damage.
Topics: Action Potentials; Analgesics, Opioid; Animals; Anti-Anxiety Agents; Calcium Channel Blockers; Cholecystokinin; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Indoles; Inflammation; Lamotrigine; Male; Meglumine; Mustard Plant; Neural Pathways; Nociceptors; Opioid Peptides; Pain; Peripheral Nervous System Diseases; Plant Extracts; Plant Oils; Posterior Horn Cells; Rats; Rats, Wistar; Sincalide; Triazines | 2001 |
Anxiogenic effect of cholecystokinin in the dorsal periaqueductal gray.
Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Appetite Depressants; Cell Count; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Hormone Antagonists; Immunohistochemistry; Indoles; Male; Maze Learning; Meglumine; Microinjections; Neurons; Periaqueductal Gray; Proglumide; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Sincalide; Superior Colliculi; Time Factors | 2004 |
Altered action of dopamine and cholecystokinin on lateral hypothalamic neurons in rats raised under different feeding conditions.
Topics: Action Potentials; Animals; Animals, Newborn; Benzazepines; Cholecystokinin; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiologic Techniques, Cardiac; Feeding Behavior; Hypothalamus; Indoles; Male; Meglumine; Neurons; Nootropic Agents; Rats; Rats, Wistar; Receptors, Cholecystokinin; Salicylamides; Sincalide | 2003 |
Localization of CCK-1R in the omasum and role of CCK in the regulation of omasal contractions in sheep.
Topics: Animals; Atropine; Electromyography; Hormone Antagonists; In Vitro Techniques; Indoles; Meglumine; Muscle Contraction; Omasum; Proglumide; Receptors, Cholecystokinin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sheep; Sincalide; Tetrodotoxin | 2008 |