pd 135158 has been researched along with morphine in 6 studies
| Studies (pd 135158) | Trials (pd 135158) | Recent Studies (post-2010) (pd 135158) | Studies (morphine) | Trials (morphine) | Recent Studies (post-2010) (morphine) |
|---|---|---|---|---|---|
| 51 | 0 | 0 | 44,270 | 5,200 | 8,695 |
| Protein | Taxonomy | pd 135158 (IC50) | morphine (IC50) |
|---|---|---|---|
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.2939 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.2278 | |
| Kappa-type opioid receptor | Mus musculus (house mouse) | 0.0828 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0385 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0545 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.122 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1199 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.9308 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.655 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.3305 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.202 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dickenson, AH; Hewett, K; Sullivan, AF | 1 |
| Choi, YS; Kim, YH; Song, DK; Suh, HW | 1 |
| Fujimoto, JM; Lin, W; Rady, JJ | 1 |
| Fujimoto, JM; Holmes, BB; Rady, JJ | 1 |
| Fujimoto, JM; Holmes, BB; Rady, JJ; Smith, DJ | 1 |
| Sakashita, Y; Yamamoto, T | 1 |
6 other study(ies) available for pd 135158 and morphine
| Article | Year |
|---|---|
Differential modulation of alpha 2-adrenergic and opioid spinal antinociception by cholecystokinin and cholecystokinin antagonists in the rat dorsal horn: an electrophysiological study.
Topics: Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Anxiety Agents; Benzodiazepinones; Cholecystokinin; Electrophysiology; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Enkephalins; Imidazoles; Indoles; Injections, Spinal; Male; Medetomidine; Meglumine; Morphine; Nerve Fibers; Phenylurea Compounds; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Receptors, Cholecystokinin; Receptors, Opioid; Spinal Cord | 1994 |
Involvement of different subtypes of cholecystokinin receptors in opioid antinociception in the mouse.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesia; Analgesics; Animals; beta-Endorphin; Drug Interactions; Enkephalin, D-Penicillamine (2,5)-; Enkephalins; Indoles; Injections, Intraventricular; Male; Meglumine; Mice; Mice, Inbred ICR; Morphine; Narcotics; Pain Measurement; Proglumide; Pyrrolidines; Receptors, Cholecystokinin; Sincalide | 1995 |
Pentobarbital antagonism of morphine analgesia mediated by spinal cholecystokinin.
Topics: Animals; Cholecystokinin; Dose-Response Relationship, Drug; Indoles; Male; Meglumine; Mice; Morphine; Pentobarbital; Proglumide; Receptor, Cholecystokinin A; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Spinal Cord | 1998 |
Antianalgesic action of dynorphin A mediated by spinal cholecystokinin.
Topics: Analgesia; Analgesics; Animals; Antibodies; Cholecystokinin; Dynorphins; Enkephalin, D-Penicillamine (2,5)-; Enkephalin, Leucine; Enkephalins; Indoles; Injections, Spinal; Male; Meglumine; Mice; Morphine; Proglumide; Receptors, Cholecystokinin; Receptors, Opioid, delta; Spinal Cord | 1999 |
Supraspinal neurotensin-induced antianalgesia in mice is mediated by spinal cholecystokinin.
Topics: Analgesics, Opioid; Animals; Anti-Anxiety Agents; Cholecystokinin; Dose-Response Relationship, Drug; Drug Interactions; Hormone Antagonists; Immune Sera; Indoles; Injections, Intraventricular; Injections, Spinal; Male; Meglumine; Mice; Morphine; Neurotensin; Proglumide; Receptors, Cholecystokinin | 1999 |
Differential effects of intrathecally administered morphine and its interaction with cholecystokinin-B antagonist on thermal hyperalgesia following two models of experimental mononeuropathy in the rat.
Topics: Analgesics, Opioid; Animals; Drug Synergism; Hot Temperature; Hyperalgesia; Indoles; Injections, Spinal; Male; Meglumine; Morphine; Naloxone; Rats; Rats, Sprague-Dawley; Receptor, Cholecystokinin B; Receptors, Cholecystokinin; Sciatic Nerve | 1999 |