pd 128483 has been researched along with amphetamine in 1 studies
*Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE. [MeSH]
*Amphetamine: A powerful central nervous system stimulant and sympathomimetic. Amphetamine has multiple mechanisms of action including blocking uptake of adrenergics and dopamine, stimulation of release of monamines, and inhibiting monoamine oxidase. Amphetamine is also a drug of abuse and a psychotomimetic. The l- and the d,l-forms are included here. The l-form has less central nervous system activity but stronger cardiovascular effects. The d-form is DEXTROAMPHETAMINE. [MeSH]
| Studies (pd 128483) | Trials (pd 128483) | Recent Studies (post-2010) (pd 128483) | Studies (amphetamine) | Trials (amphetamine) | Recent Studies (post-2010) (amphetamine) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 13,071 | 329 | 1,977 |
| Protein | Taxonomy | pd 128483 (IC50) | amphetamine (IC50) |
|---|---|---|---|
| Phenylethanolamine N-methyltransferase | Bos taurus (cattle) | 0.96 | |
| Cytochrome P450 2A6 | Homo sapiens (human) | 3.5 | |
| Cytochrome P450 2A5 | Mus musculus (house mouse) | 2.85 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.96 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.96 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Caprathe, BW; Christoffersen, CL; Corbin, AE; Jaen, JC; Meltzer, LT; Ninteman, FW; Pugsley, TA; Serpa, KA; Shih, YH; Whetzel, SZ | 1 |
1 other study(ies) available for pd 128483 and amphetamine
| Article | Year |
|---|---|
Pharmacological profile of the dopamine partial agonist, (+/-)-PD 128483 and its enantiomers.
Topics: 4-Butyrolactone; Aminoquinolines; Amphetamine; Animals; Apomorphine; Avoidance Learning; Behavior, Animal; Cebus; Dopamine; Dopamine Agents; Dose-Response Relationship, Drug; Extrapyramidal Tracts; Male; Mice; Motor Activity; Neurons; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Saimiri; Serotonin; Stereoisomerism; Stereotyped Behavior; Stimulation, Chemical; Thiazoles | 1993 |