Compounds > pd 123177
Page last updated: 2024-09-02

pd 123177 and propranolol

pd 123177 has been researched along with propranolol in 3 studies

Compound Research Comparison

Studies
(pd 123177)		Trials
(pd 123177)		Recent Studies (post-2010)
(pd 123177)		Studies
(propranolol)		Trials
(propranolol)		Recent Studies (post-2010) (propranolol)
1420233,3103,4063,218

Protein Interaction Comparison

ProteinTaxonomypd 123177 (IC50)propranolol (IC50)
Beta-1 adrenergic receptor Cavia porcellus (domestic guinea pig)0.0347
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.0288
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)2.294
Cytochrome P450 1A2Homo sapiens (human)4
Beta-2 adrenergic receptorHomo sapiens (human)0.0114
Beta-1 adrenergic receptorHomo sapiens (human)0.0575
5-hydroxytryptamine receptor 1AHomo sapiens (human)3.9811
Beta-2 adrenergic receptorRattus norvegicus (Norway rat)0.012
Cytochrome P450 2D6Homo sapiens (human)2.9706
Beta-3 adrenergic receptorHomo sapiens (human)0.0493
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.0288
Beta-1 adrenergic receptorRattus norvegicus (Norway rat)0.012
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.0288
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0827
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0288
Beta-3 adrenergic receptorRattus norvegicus (Norway rat)0.012
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.466
5-hydroxytryptamine receptor 2CHomo sapiens (human)2.294
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.0288
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.243
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.0288
Sodium-dependent serotonin transporterHomo sapiens (human)0.38
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.342
5-hydroxytryptamine receptor 6Homo sapiens (human)3.065
Beta-2 adrenergic receptorCanis lupus familiaris (dog)0.017
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.0288
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.0288
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)2.828
Sodium channel protein type 5 subunit alphaHomo sapiens (human)2.1
Sodium/bile acid cotransporterHomo sapiens (human)5.5
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.0288
GABA theta subunitRattus norvegicus (Norway rat)0.0288
Sigma non-opioid intracellular receptor 1Homo sapiens (human)2.87
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.0288

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pfaffendorf, M; van Zwieten, PA; Zhang, J2
Couch, SJ; Pals, DT1

Other Studies

3 other study(ies) available for pd 123177 and propranolol

ArticleYear
Effect of various angiotensin receptor antagonists on cardiovascular responses to angiotensin II in pithed rats.
    Journal of cardiovascular pharmacology, 1994, Volume: 24, Issue:1

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Cardiac Output; Cardiovascular Physiological Phenomena; Cardiovascular System; Heart Rate; Imidazoles; Losartan; Male; Methylurea Compounds; Propranolol; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles

1994
Hemodynamic effects of angiotensin II and the influence of angiotensin receptor antagonists in pithed rabbits.
    Journal of cardiovascular pharmacology, 1995, Volume: 25, Issue:5

    Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Decerebrate State; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Losartan; Male; Methylurea Compounds; Propranolol; Pyridines; Rabbits; Tetrazoles; Ventricular Function, Left

1995
Renin release induced by losartan (DuP 753), an angiotensin II receptor antagonist.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1993, Volume: 15, Issue:1

    Topics: Angiotensin Receptor Antagonists; Animals; Atenolol; Biphenyl Compounds; Dose-Response Relationship, Drug; Feedback; Imidazoles; Indomethacin; Injections, Intravenous; Losartan; Male; Meclofenamic Acid; Propranolol; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Angiotensin; Renin; Sympathetic Nervous System; Tetrazoles

1993