Page last updated: 2024-09-02

pd 123177 and 3-((2'-carboxybiphenyl-4-yl)methyl)-2-cyclopropyl-7-methyl-3h-imidazo(4,5-b)pyridine

pd 123177 has been researched along with 3-((2'-carboxybiphenyl-4-yl)methyl)-2-cyclopropyl-7-methyl-3h-imidazo(4,5-b)pyridine in 2 studies

Compound Research Comparison

Studies (pd 123177)	Trials (pd 123177)	Recent Studies (post-2010) (pd 123177)	Studies (3-((2'-carboxybiphenyl-4-yl)methyl)-2-cyclopropyl-7-methyl-3h-imidazo(4,5-b)pyridine)	Trials (3-((2'-carboxybiphenyl-4-yl)methyl)-2-cyclopropyl-7-methyl-3h-imidazo(4,5-b)pyridine)	Recent Studies (post-2010) (3-((2'-carboxybiphenyl-4-yl)methyl)-2-cyclopropyl-7-methyl-3h-imidazo(4,5-b)pyridine)
142	0	2	20	0	0

Protein Interaction Comparison

Protein	Taxonomy	pd 123177 (IC50)	3-((2'-carboxybiphenyl-4-yl)methyl)-2-cyclopropyl-7-methyl-3h-imidazo(4,5-b)pyridine (IC50)
Type-1A angiotensin II receptor	Rattus norvegicus (Norway rat)		0.052
Type-1B angiotensin II receptor	Rattus norvegicus (Norway rat)		0.052

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Horie, T; Kakiki, M; Morohashi, K; Nomura, M; Omura, T	2

Other Studies

2 other study(ies) available for pd 123177 and 3-((2'-carboxybiphenyl-4-yl)methyl)-2-cyclopropyl-7-methyl-3h-imidazo(4,5-b)pyridine

Article	Year
Regulation of aldosterone synthase cytochrome P450 (CYP11B2) and 11 beta-hydroxylase cytochrome P450 (CYP11B1) expression in rat adrenal zona glomerulosa cells by low sodium diet and angiotensin II receptor antagonists. Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:9 Topics: Aldosterone; Angiotensin Receptor Antagonists; Animals; Cytochrome P-450 CYP11B2; Imidazoles; Linear Models; Male; Polymerase Chain Reaction; Pyridines; Rats; Rats, Sprague-Dawley; Sodium, Dietary; Steroid 11-beta-Hydroxylase; Transcription, Genetic; Zona Glomerulosa	1997
Expression of aldosterone synthase cytochrome P450 (P450aldo) mRNA in rat adrenal glomerulosa cells by angiotensin II type 1 receptor. Endocrine research, 1997, Volume: 23, Issue:4 Topics: Aldosterone; Angiotensin II; Animals; Cytochrome P-450 CYP11B2; Gene Expression; Humans; Imidazoles; Male; Polymerase Chain Reaction; Pyridines; Rats; Rats, Sprague-Dawley; Renin; RNA; RNA, Messenger; Sodium, Dietary; Steroid 11-beta-Hydroxylase; Transcription, Genetic; Zona Glomerulosa	1997

Article

Year

Regulation of aldosterone synthase cytochrome P450 (CYP11B2) and 11 beta-hydroxylase cytochrome P450 (CYP11B1) expression in rat adrenal zona glomerulosa cells by low sodium diet and angiotensin II receptor antagonists.

Biological & pharmaceutical bulletin, 1997, Volume: 20, Issue:9

Topics: Aldosterone; Angiotensin Receptor Antagonists; Animals; Cytochrome P-450 CYP11B2; Imidazoles; Linear Models; Male; Polymerase Chain Reaction; Pyridines; Rats; Rats, Sprague-Dawley; Sodium, Dietary; Steroid 11-beta-Hydroxylase; Transcription, Genetic; Zona Glomerulosa

1997

Expression of aldosterone synthase cytochrome P450 (P450aldo) mRNA in rat adrenal glomerulosa cells by angiotensin II type 1 receptor.

Endocrine research, 1997, Volume: 23, Issue:4

Topics: Aldosterone; Angiotensin II; Animals; Cytochrome P-450 CYP11B2; Gene Expression; Humans; Imidazoles; Male; Polymerase Chain Reaction; Pyridines; Rats; Rats, Sprague-Dawley; Renin; RNA; RNA, Messenger; Sodium, Dietary; Steroid 11-beta-Hydroxylase; Transcription, Genetic; Zona Glomerulosa

1997