pd-117596 has been researched along with amsacrine in 1 studies
*Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent. [MeSH]
*Amsacrine: An aminoacridine derivative that intercalates into DNA and is used as an antineoplastic agent. [MeSH]
| Studies (pd-117596) | Trials (pd-117596) | Recent Studies (post-2010) (pd-117596) | Studies (amsacrine) | Trials (amsacrine) | Recent Studies (post-2010) (amsacrine) |
|---|---|---|---|---|---|
| 21 | 0 | 0 | 1,293 | 127 | 120 |
| Protein | Taxonomy | pd-117596 (IC50) | amsacrine (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 1 | Homo sapiens (human) | 5 | |
| Multidrug resistance-associated protein 4 | Homo sapiens (human) | 7.43 | |
| DNA topoisomerase 2-alpha | Homo sapiens (human) | 5.47 | |
| 5-hydroxytryptamine receptor 7 | Cavia porcellus (domestic guinea pig) | 5 | |
| DNA topoisomerase 2-beta | Homo sapiens (human) | 1.88 | |
| Aldehyde oxidase | Homo sapiens (human) | 3.2 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 0.2095 | |
| Aldehyde oxidase 1 | Rattus norvegicus (Norway rat) | 6.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aldous, SC; Coughlin, SA; Dorff, PH; Gruett, MD; Lesher, GY; Rake, JB; Reuman, M; Singh, B; Wentland, MP | 1 |
1 other study(ies) available for pd-117596 and amsacrine
| Article | Year |
|---|---|
Mammalian topoisomerase II inhibitory activity of 1-cyclopropyl-6,8- difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarb oxylic acid and related derivatives.
Topics: Animals; Anti-Infective Agents; Fluoroquinolones; HeLa Cells; Humans; Leukemia P388; Mice; Quinolones; Structure-Activity Relationship; Topoisomerase II Inhibitors | 1993 |