pd 117302 has been researched along with spiradoline in 2 studies
Studies (pd 117302) | Trials (pd 117302) | Recent Studies (post-2010) (pd 117302) | Studies (spiradoline) | Trials (spiradoline) | Recent Studies (post-2010) (spiradoline) |
---|---|---|---|---|---|
48 | 0 | 2 | 132 | 6 | 24 |
Protein | Taxonomy | pd 117302 (IC50) | spiradoline (IC50) |
---|---|---|---|
Mu-type opioid receptor | Homo sapiens (human) | 0.234 | |
Kappa-type opioid receptor | Homo sapiens (human) | 0.0083 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (50.00) | 18.7374 |
1990's | 1 (50.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Boyle, SJ; Hughes, J; Hunter, JC; Meecham, KG | 1 |
Holtzman, SG; Powell, KR | 1 |
2 other study(ies) available for pd 117302 and spiradoline
Article | Year |
---|---|
An in vitro profile of activity for the (+) and (-) enantiomers of spiradoline and PD117302.
Topics: Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Pyrroles; Pyrrolidines; Rabbits; Rats; Rats, Inbred Strains; Receptors, Opioid; Receptors, Opioid, kappa; Receptors, Opioid, mu; Stereoisomerism; Thiophenes; Vas Deferens | 1989 |
Differential antagonism of the rate-decreasing effects of kappa-opioid receptor agonists by naltrexone and norbinaltorphimine.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Analgesics; Animals; Behavior, Animal; Benzeneacetamides; Benzofurans; Benzomorphans; Conditioning, Operant; Dose-Response Relationship, Drug; Ethylketocyclazocine; Nalorphine; Naltrexone; Narcotic Antagonists; Pyrroles; Pyrrolidines; Receptors, Opioid, kappa; Reinforcement Schedule; Saimiri; Thiophenes | 1999 |