Compounds > pca 4248

pca 4248 and dihydropyridines

pca 4248 has been researched along with dihydropyridines in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (61.54)18.2507
2000's5 (19.23)29.6817
2010's5 (19.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Lima, MC; Martins, MA; Silva, AR; Silva, PM; Vargaftig, BB1
Achiwa, K; Ebiike, H; Maruyama, K1
Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Correia-Da-Silva, AC; Martins, MA; Morhy, L; Sousa, MV1
de Casa-Juana, MF; García, MC; Gijón, MA; Ortega, MP; Priego, JG; Sanchez Crespo, M; Sunkel, C1
de Casa-Juana, MF; Fernández-Gallardo, S; Ortega, MP; Priego, JG; Sánchez Crespo, M; Sunkel, C1
de Casa-Juana, MF; Gómez, MM; González-Morales, MA; Ortega, MP; Priego, JG; Santos, L; Sunkel, CE; Villarroya, M1
Aragonés, MD; Catalán, RE; Garde, E; Lombardía, M; Martínez, AM1
Desquand, S; Hatmi, M; Lefort, J; Pina, M; Priego, JG; Ruffié, C; Vargaftig, BB1
Aragonés, MD; Calcerrada, MC; Catalán, RE; Fernández, I; Martínez, AM; Miguel, BG; Pérez, MJ1
Bozza, PT; Castro-Faria-Neto, HC; Cordeiro, RS; Larangeira, AP; Martins, MA; Silva, AR; Silva, PM1
Amorim, CZ; Cordeiro, RS; Vargaftig, BB1
Cárdenas, AM; Cortés, MP; Fernández, E; Glena, C; Hidalgo, ME; Sunkel, C1
Bozza, PT; Cordeiro, RS; Faria Neto, HC; Lima, MC; Martins, MA; Silva, PM; Sunkel, CE1
Calcerrada, MC; Catalán, RE; Hernández, F; Martínez, AM; Pérez, MJ1
Ferreira, MG; Fonteles, MC1
Jan, CR; Tseng, CJ; Wu, SN1
Bolsover, S; Ranasinghe, S1
Antunes, E; Coelho, MB; Desouza, IA; Freire, MG; Macedo, ML; Marangoni, S1
Byrne, SN; Matsumura, Y; Miyahara, Y; Nghiem, DX; Ullrich, SE1
Bar-Eli, M; Melnikova, V1
Amidi, F; Bardag-Gorce, F; Dedes, J; French, BA; French, SW; Habibi, A; Li, J; McPhaul, L; Nguyen, S; Oliva, J1
Cassali, GD; Fagundes, CT; Garcia, CC; Guabiraba, R; Machado, AV; Polidoro, RB; Russo, RC; Salgado, AP; Sousa, LP; Tavares, LP; Teixeira, MM1
Bambach, I; Huettner, B; Koefeler, H; Mayer, G; Schön, MP; Singh, TP; Wallbrecht, K; Wolf, P1
Cunha, FQ; Cunha, TM; Ferreira, SH; Guerrero, AT; Pinto, LG; Verri, WA; Vieira, SM; Zaperlon, AC; Zarpelon, AC1
Chu, YF; Feng, J; Jia, HZ; Wang, HF; Zhang, XZ; Zhuo, RX1
Borges, AF; de Oliveira, MAP; Dorta, ML; Gomes, RS; Morato, CI; Ribeiro-Dias, F1

Reviews

1 review(s) available for pca 4248 and dihydropyridines

ArticleYear
Inflammation and melanoma growth and metastasis: the role of platelet-activating factor (PAF) and its receptor.
    Cancer metastasis reviews, 2007, Volume: 26, Issue:3-4

    Topics: Animals; Cyclic AMP Response Element-Binding Protein; Dihydropyridines; Humans; Inflammation; Lung Neoplasms; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Melanoma; Neovascularization, Pathologic; Platelet Activating Factor; Platelet Membrane Glycoproteins; Proteins; Receptors, G-Protein-Coupled; Signal Transduction

2007

Other Studies

25 other study(ies) available for pca 4248 and dihydropyridines

ArticleYear
Interference of azelastine with anaphylaxis induced by ovalbumin challenge in actively sensitized rats.
    European journal of pharmacology, 1992, Mar-24, Volume: 213, Issue:2

    Topics: Anaphylaxis; Animals; Azepines; Dihydropyridines; Dose-Response Relationship, Drug; Hematocrit; Histamine H1 Antagonists; Leukocyte Count; Male; Meclizine; Ovalbumin; Phthalazines; Platelet Activating Factor; Platelet Count; Rats; Rats, Inbred Strains; Terfenadine; Triazoles

1992
Lipase-catalyzed enantioselective hydrolysis of 4-alkyl-1,4-dihydropyridine derivatives: synthesis of (+)- and (-)-methyl 2-(phenylthio)ethyl 1,4-dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylate (PCA 4248).
    Chemical & pharmaceutical bulletin, 1992, Volume: 40, Issue:4

    Topics: Dihydropyridines; Hydrolysis; Lipase; Platelet Activating Factor; Stereoisomerism

1992
Enterolobin induces rat paw oedema independently of PAF-acether.
    Memorias do Instituto Oswaldo Cruz, 1991, Volume: 86 Suppl 2

    Topics: Animals; Azepines; Dihydropyridines; Diterpenes; Edema; Ginkgolides; Lactones; Male; Plant Proteins; Platelet Activating Factor; Rats; Rats, Wistar; Triazoles

1991
1,4-Dihydropyridines, a new class of platelet-activating factor receptor antagonists: in vitro pharmacologic studies.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:1

    Topics: Animals; Blood Platelets; Dihydropyridines; Humans; In Vitro Techniques; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin

1990
Pharmacological actions of PCA 4248, a new platelet-activating factor receptor antagonist: in vivo studies.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:1

    Topics: Animals; Blood Pressure; Capillary Permeability; Dihydropyridines; Endotoxins; Male; Mice; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tumor Necrosis Factor-alpha

1990
4-Alkyl-1,4-dihydropyridines derivatives as specific PAF-acether antagonists.
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:12

    Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Blood Platelets; Blood Pressure; Chemical Phenomena; Chemistry; Dihydropyridines; Heart Rate; Ileum; Male; Microsomes; Molecular Structure; Muscle Contraction; Myocardial Contraction; Nitrendipine; Platelet Activating Factor; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Rabbits; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, G-Protein-Coupled

1990
PCA-4248, a PAF receptor antagonist, inhibits PAF-induced phosphoinositide turnover.
    European journal of pharmacology, 1995, Aug-15, Volume: 290, Issue:3

    Topics: Animals; Blood Platelets; Cell Membrane; Dihydropyridines; In Vitro Techniques; Kinetics; Phosphatidylinositols; Phosphorus Radioisotopes; Phosphorylation; Platelet Activating Factor; Platelet Membrane Glycoproteins; Rabbits; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin

1995
Compound PCA-4248 interferes with bronchopulmonary anaphylaxis and with in vitro hyperresponsiveness to platelet-activating factor.
    European journal of pharmacology, 1993, Apr-22, Volume: 235, Issue:1

    Topics: Anaphylaxis; Animals; Blood Cell Count; Bronchial Hyperreactivity; Bronchoconstriction; Dihydropyridines; Female; Guinea Pigs; Histamine Release; Immunization; In Vitro Techniques; Injections, Intravenous; Lung; Male; Platelet Activating Factor; Radioimmunoassay; Thromboxane B2

1993
Platelet-activating factor inhibits (Na+,K+) ATPase activity in rat brain.
    Neuroscience research, 1994, Volume: 19, Issue:2

    Topics: Animals; Brain; Calcium; Dihydropyridines; Egtazic Acid; In Vitro Techniques; Male; Platelet Activating Factor; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase

1994
Lipopolysaccharide-induced pleural neutrophil accumulation depends on marrow neutrophils and platelet-activating factor.
    European journal of pharmacology, 1994, Apr-04, Volume: 270, Issue:2-3

    Topics: Animals; Azepines; Bone Marrow; Bone Marrow Cells; Cell Cycle; Cell Movement; Dihydropyridines; Escherichia coli; Injections; Kinetics; Leukocyte Count; Lipopolysaccharides; Male; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleura; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thorax; Triazoles

1994
Interference of PCA 4248, a novel PAF receptor antagonist, with antigen-induced paw edema in mice.
    European journal of pharmacology, 1993, May-19, Volume: 236, Issue:2

    Topics: Animals; Dihydropyridines; Edema; Injections, Intraperitoneal; Male; Mice; Ovalbumin; Platelet Activating Factor

1993
New 4-alkyl-1,4-dihydropyridines: evaluation of photostability and phototoxic potential.
    Journal of photochemistry and photobiology. B, Biology, 1993, Volume: 19, Issue:2

    Topics: Carcinoma, Squamous Cell; Cell Survival; Dihydropyridines; Erythrocytes; Fibrinolytic Agents; Humans; Kinetics; Light; Molecular Structure; Photosensitizing Agents; Time Factors; Tumor Cells, Cultured

1993
Interference of the PAF receptor antagonist, PCA 4248, with the rat pleurisy evoked by inflammatory mediators or allergen.
    European journal of pharmacology, 1993, Jun-11, Volume: 237, Issue:1

    Topics: Allergens; Animals; Bradykinin; Dihydropyridines; Edema; Eosinophils; Exudates and Transudates; Female; Histamine; Hypersensitivity; Leukocyte Count; Male; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Pleurisy; Rats; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Serotonin

1993
Nitric oxide mediates the PAF-stimulated cyclic GMP production in hippocampal slices.
    Biochemical and biophysical research communications, 1996, Sep-04, Volume: 226, Issue:1

    Topics: Animals; Arginine; Cyclic GMP; Dihydropyridines; Enzyme Inhibitors; Hippocampus; In Vitro Techniques; Male; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Platelet Activating Factor; Rats; Rats, Wistar

1996
Different classes of PAF-antagonists block norepinephrine-induced vascular escape and tachyphylaxis in the isolated rabbit kidney.
    Research communications in molecular pathology and pharmacology, 1996, Volume: 94, Issue:2

    Topics: Animals; Azepines; Dihydropyridines; Ginkgolides; In Vitro Techniques; Kidney; Lactones; Norepinephrine; Platelet Activating Factor; Rabbits; Tachyphylaxis; Triazoles; Vasoconstriction

1996
The ether lipid ET-18-OCH3 increases cytosolic Ca2+ concentrations in Madin Darby canine kidney cells.
    British journal of pharmacology, 1999, Volume: 127, Issue:6

    Topics: Adenosine Triphosphate; Animals; Calcium; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line; Cytosol; Dihydropyridines; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Kidney; Phosphodiesterase Inhibitors; Phospholipid Ethers; Platelet Membrane Glycoproteins; Pyrrolidinones; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Thapsigargin; Type C Phospholipases; Uncoupling Agents

1999
Microglial calcium responses to platelet-activating factor are inhibited by analogue CAS 99103-16-9 and dihydropyridine PCA 4248 but not by ginkgolide A.
    Basic & clinical pharmacology & toxicology, 2004, Volume: 95, Issue:2

    Topics: Aniline Compounds; Calcium; Calcium Signaling; Cell Line; Dihydropyridines; Diterpenes; Ginkgolides; Glyceryl Ethers; Humans; Lactones; Microglia; Platelet Activating Factor; United Kingdom; Xanthenes

2004
Neutrophil migration in mice induced by a mannose-binding lectin isolated from Annona coriacea seeds.
    Toxicon : official journal of the International Society on Toxinology, 2006, Volume: 48, Issue:5

    Topics: Animals; Annona; Celecoxib; Chemotaxis, Leukocyte; Dihydropyridines; Dose-Response Relationship, Drug; Leukocytes, Mononuclear; Male; Mannose; Mannose-Binding Lectin; Mice; Neutrophils; Peritoneal Cavity; Plant Extracts; Pyrazoles; Seeds; Sulfonamides

2006
A role for inflammatory mediators in the induction of immunoregulatory B cells.
    Journal of immunology (Baltimore, Md. : 1950), 2006, Oct-01, Volume: 177, Issue:7

    Topics: Adoptive Transfer; Animals; Antigens, CD19; B-Lymphocytes; Dermatitis, Contact; Dihydropyridines; Flow Cytometry; Fluorescein-5-isothiocyanate; Immune Tolerance; Inflammation; Interleukin-10; Leukocyte Common Antigens; Lymphocyte Activation; Mice; Mice, Mutant Strains; Platelet Activating Factor; Serotonin; Serotonin Antagonists; Ultraviolet Rays

2006
Fat10 is an epigenetic marker for liver preneoplasia in a drug-primed mouse model of tumorigenesis.
    Experimental and molecular pathology, 2008, Volume: 84, Issue:2

    Topics: Animals; Carcinogens; Cells, Cultured; Dihydropyridines; Disease Models, Animal; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Hepatocytes; Hydroxamic Acids; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred C3H; Oligonucleotide Array Sequence Analysis; Precancerous Conditions; Proteins; Ubiquitins; Up-Regulation

2008
Platelet-activating factor receptor plays a role in lung injury and death caused by Influenza A in mice.
    PLoS pathogens, 2010, Nov-04, Volume: 6, Issue:11

    Topics: Animals; Apoptosis; Blotting, Western; Chickens; Dihydropyridines; Disease Models, Animal; Inflammation Mediators; Influenza A Virus, H1N1 Subtype; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Orthomyxoviridae Infections; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Survival Rate; Toll-Like Receptors; Viral Load

2010
Platelet-activating factor blockade inhibits the T-helper type 17 cell pathway and suppresses psoriasis-like skin disease in K5.hTGF-β1 transgenic mice.
    The American journal of pathology, 2011, Volume: 178, Issue:2

    Topics: Animals; Cytokines; Dihydropyridines; Disease Progression; Down-Regulation; Humans; Mice; Mice, Transgenic; Phenotype; Platelet Activating Factor; Platelet Membrane Glycoproteins; Psoriasis; PUVA Therapy; Receptors, G-Protein-Coupled; RNA, Messenger; Signal Transduction; Skin; STAT3 Transcription Factor; Th17 Cells; Transforming Growth Factor beta1; Up-Regulation

2011
The role of PAF/PAFR signaling in zymosan-induced articular inflammatory hyperalgesia.
    Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:1

    Topics: Animals; Dihydropyridines; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Immune System Diseases; Inflammation; Joint Diseases; Leukocyte Disorders; Leukotriene B4; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Neutrophils; Platelet Activating Factor; Platelet Membrane Glycoproteins; Prostaglandins; Receptors, G-Protein-Coupled; Time Factors; Zymosan

2013
Acidity-promoted cellular uptake and drug release mediated by amine-functionalized block polycarbonates prepared via one-shot ring-opening copolymerization.
    Macromolecular bioscience, 2014, Volume: 14, Issue:4

    Topics: Amines; Camptothecin; Dihydropyridines; Doxorubicin; Drug Liberation; HeLa Cells; Humans; Hydrogen-Ion Concentration; Neoplasms; Polymers

2014
Platelet-activating factor increases reactive oxygen species-mediated microbicidal activity of human macrophages infected with Leishmania (Viannia) braziliensis.
    Pathogens and disease, 2017, 09-29, Volume: 75, Issue:7

    Topics: Acetophenones; Dihydropyridines; Enzyme Inhibitors; Gene Expression; Humans; Leishmania braziliensis; Macrophages; NADPH Oxidases; Phagocytosis; Platelet Activating Factor; Primary Cell Culture; Reactive Oxygen Species; Respiratory Burst

2017