Page last updated: 2024-09-03

pca 4230 and dihydropyridines

pca 4230 has been researched along with dihydropyridines in 8 studies

Compound Research Comparison

Studies
(pca 4230)
Trials
(pca 4230)
Recent Studies (post-2010)
(pca 4230)
Studies
(dihydropyridines)
Trials
(dihydropyridines)
Recent Studies (post-2010) (dihydropyridines)
9005,022529969

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (87.50)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Alonso, MT; Sanchez, A; Villalobos, C1
Gutiérrez Díaz, JA; Ortega, MP; Priego, JG; Sunkel, C; Tolón, RM1
Aragonés, MD; Catalán, RE; Garde, E; Hernández, F; Lombardía, M; Martínez, AM1
Cárdenas, AM; Cortés, MP; Fernández, E; Glena, C; Hidalgo, ME; Sunkel, C1
Aragonés, MD; Catalán, RE; Garde, E; Lombardía, M; Martínez, AM; Ortega, P1
del Rio, M; Larcher, F; Ortega, MP; Sunkel, C1
Aragonés, MD; Catalán, RE; Lombardía, M; Martínez, AM1
Andrés, V; Font de Mora, J; Goukassian, D; Pérez-Roger, I; Sanz-González, SM; Ureña, J1

Other Studies

8 other study(ies) available for pca 4230 and dihydropyridines

ArticleYear
Effects of the antithrombitic agent PCA 4230 on agonist-induced Ca2+ entry and Ca2+ release in human platelets.
    Biochimica et biophysica acta, 1992, Mar-02, Volume: 1104, Issue:2

    Topics: Blood Platelets; Calcium; Calcium Channels; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dihydropyridines; Fura-2; Humans; Indoles; Manganese; Platelet Activating Factor; Thrombin

1992
Interaction of platelets with subendothelium in rats treated with PCA-4230, a new antithrombotic agent. Effect of PCA-4230 on experimental thrombosis.
    Haemostasis, 1992, Volume: 22, Issue:4

    Topics: Animals; Blood Platelets; Carotid Arteries; Dihydropyridines; Fibrinogen; Fibrinolytic Agents; Male; Platelet Membrane Glycoproteins; Rats; Rats, Sprague-Dawley; Thrombosis; Thromboxane B2; Ticlopidine

1992
Dissociation between secretion and protein phosphorylation in agonist-stimulated platelets; action of PCA-4230, a new antithrombotic drug.
    Thrombosis research, 1994, Jul-15, Volume: 75, Issue:2

    Topics: Animals; Blood Platelets; Blood Proteins; Calcimycin; Cytoplasmic Granules; Dihydropyridines; Fibrinolytic Agents; Phosphorylation; Platelet Activating Factor; Rabbits; Thrombin

1994
New 4-alkyl-1,4-dihydropyridines: evaluation of photostability and phototoxic potential.
    Journal of photochemistry and photobiology. B, Biology, 1993, Volume: 19, Issue:2

    Topics: Carcinoma, Squamous Cell; Cell Survival; Dihydropyridines; Erythrocytes; Fibrinolytic Agents; Humans; Kinetics; Light; Molecular Structure; Photosensitizing Agents; Time Factors; Tumor Cells, Cultured

1993
PAF and thrombin actions in platelets are selectively affected by a new 1,4-dihydropyridine derivative.
    Journal of biochemistry, 1993, Volume: 113, Issue:4

    Topics: Animals; Arachidonic Acid; Blood Platelets; Diglycerides; Dihydropyridines; Phosphatidylinositols; Platelet Activating Factor; Platelet Aggregation; Rabbits; Thrombin; Type C Phospholipases

1993
Antiproliferative effects of PCA-4230, a new antithrombotic drug, in vascular smooth muscle cells.
    British journal of pharmacology, 1997, Volume: 120, Issue:7

    Topics: Animals; Cattle; Cell Division; Cell Line; Dihydropyridines; DNA Replication; Fibrinolytic Agents; Gene Expression Regulation; Muscle, Smooth, Vascular; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Proto-Oncogenes; Rats; RNA, Messenger

1997
Involvement of cyclic GMP in the mode of action of a new antithrombotic agent PCA-4230; inhibition of the platelet cyclic GMP dependent phosphodiesterase.
    Thrombosis research, 1997, Sep-15, Volume: 87, Issue:6

    Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; Colforsin; Cyclic AMP; Cyclic GMP; Dihydropyridines; Drug Synergism; Fibrinolytic Agents; Kinetics; Nitroprusside; Phosphodiesterase Inhibitors; Phosphorylation; Rabbits; Serotonin; Thrombin; Vasodilator Agents

1997
Inhibition of the cyclin D1/E2F pathway by PCA-4230, a potent repressor of cellular proliferation.
    British journal of pharmacology, 2001, Volume: 132, Issue:7

    Topics: Animals; Carrier Proteins; Cell Cycle Proteins; Cell Division; Cells, Cultured; Cyclin A; Cyclin D1; Dihydropyridines; DNA-Binding Proteins; Dose-Response Relationship, Drug; E2F Transcription Factors; E2F1 Transcription Factor; Humans; Luciferases; Muscle, Smooth, Vascular; Promoter Regions, Genetic; Rats; Rats, Inbred F344; Recombinant Fusion Proteins; Retinoblastoma-Binding Protein 1; S Phase; Signal Transduction; Time Factors; Transcription Factor DP1; Transcription Factors; Tumor Cells, Cultured

2001