parthenolide has been researched along with sirolimus in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Batista-Gonzalez, A; Brunhofer, G; Fallarero, A; Gopi Mohan, C; Karlsson, D; Shinde, P; Vuorela, P | 1 |
| Balys, M; Corbett, CA; Crooks, PA; Guzman, ML; Hassane, DC; Jordan, CT; Minhajuddin, M; Rossi, RM; Sen, S; Wei, L | 1 |
| Beaupere, C; Capeau, J; Fève, B; Garcia, M; Lagathu, C; Larghero, J | 1 |
| Adane, B; Ashton, JM; Crooks, PA; D'Alessandro, A; De, S; Gutman, JA; Hagen, FK; Hansen, KC; Jordan, CT; Khan, N; Minhajuddin, M; Nemkov, T; Pei, S; Pollyea, DA; Smith, C; Stevens, BM; Yadav, VK | 1 |
4 other study(ies) available for parthenolide and sirolimus
| Article | Year |
|---|---|
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine.
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Benzophenanthridines; Binding Sites; Butyrylcholinesterase; Catalytic Domain; Cholinesterase Inhibitors; Humans; Isoquinolines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship | 2012 |
Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomarkers, Tumor; Blotting, Western; Bone Marrow; Cell Proliferation; Cells, Cultured; Drug Synergism; Enzyme Inhibitors; Flow Cytometry; Gene Expression Profiling; Humans; Leukemia, Myeloid, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Oligonucleotide Array Sequence Analysis; Phosphatidylinositol 3-Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sesquiterpenes; Sirolimus; TOR Serine-Threonine Kinases | 2010 |
The HIV proteins Tat and Nef promote human bone marrow mesenchymal stem cell senescence and alter osteoblastic differentiation.
Topics: Acetylcysteine; Antioxidants; Autophagy; Bone Marrow Cells; Cell Differentiation; Cell Proliferation; Cellular Senescence; Gene Expression Regulation; Humans; Interleukin-6; Interleukin-8; Mesenchymal Stem Cells; Mitochondria; nef Gene Products, Human Immunodeficiency Virus; NF-kappa B; Osteoblasts; Osteocalcin; Oxidative Stress; Primary Cell Culture; Recombinant Proteins; Sesquiterpenes; Signal Transduction; Sirolimus; tat Gene Products, Human Immunodeficiency Virus | 2015 |
Rational Design of a Parthenolide-based Drug Regimen That Selectively Eradicates Acute Myelogenous Leukemia Stem Cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Deoxyglucose; Female; Gene Expression Regulation, Leukemic; Humans; Leukemia, Myeloid, Acute; Male; NADP; Neoplasm Proteins; Neoplastic Stem Cells; NF-E2-Related Factor 2; Sesquiterpenes; Sirolimus; Up-Regulation | 2016 |