parthenolide and helenalin

parthenolide has been researched along with helenalin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (66.67)29.6817
2010's2 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gasteiger, J; Hofmann, A; Merfort, I; Siedle, B; Terfloth, L; Wagner, S1
Arce, R; Gasteiger, J; Merfort, I; Murillo, R; Terfloth, L; Wagner, S1
Emerenciano, VP; Fernandes, MB; Ferreira, MJ; Scotti, MT1
Da Costa, FB; Klempnauer, KH; Schmidt, TJ; Schomburg, C; Schuehly, W1
Chiarugi, A1
Cho, KM; Hwang, SY; Kim, HJ; Kim, SH; Kim, TS; Song, JH1

Other Studies

6 other study(ies) available for parthenolide and helenalin

ArticleYear
Development of a structural model for NF-kappaB inhibition of sesquiterpene lactones using self-organizing neural networks.
    Journal of medicinal chemistry, 2006, Apr-06, Volume: 49, Issue:7

    Topics: Lactones; Models, Molecular; Neural Networks, Computer; NF-kappa B; Quantitative Structure-Activity Relationship; Sesquiterpenes

2006
Neural networks as valuable tools to differentiate between sesquiterpene lactones' inhibitory activity on serotonin release and on NF-kappaB.
    Journal of medicinal chemistry, 2008, Mar-13, Volume: 51, Issue:5

    Topics: Animals; Blood Platelets; Cattle; Electricity; In Vitro Techniques; Lactones; Models, Molecular; Neural Networks, Computer; NF-kappa B; Quantitative Structure-Activity Relationship; Serotonin; Serotonin Antagonists; Sesquiterpenes

2008
Use of self-organizing maps and molecular descriptors to predict the cytotoxic activity of sesquiterpene lactones.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:10

    Topics: Antineoplastic Agents; Drug Evaluation, Preclinical; Humans; Lactones; Neural Networks, Computer; Sesquiterpenes

2008
Natural sesquiterpene lactones as inhibitors of Myb-dependent gene expression: structure-activity relationships.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Acetyltransferases; Animals; Cell Line; Cell Survival; Chickens; Computer Simulation; Dose-Response Relationship, Drug; Gene Expression; Green Fluorescent Proteins; Inhibitory Concentration 50; Lactones; Models, Molecular; Molecular Conformation; Molecular Structure; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myb; Sesquiterpenes; Structure-Activity Relationship

2013
Characterization of the molecular events following impairment of NF-kappaB-driven transcription in neurons.
    Brain research. Molecular brain research, 2002, Dec-30, Volume: 109, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Caspases; Cells, Cultured; Cerebral Cortex; Cytochrome c Group; DNA; DNA-Binding Proteins; Homeostasis; Mitochondria; Neurons; NF-kappa B; Nitriles; Organic Chemicals; Peptides; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Protein Binding; Protein Precursors; Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Replication Protein C; Sesquiterpenes; Sesquiterpenes, Guaiane; Sulfones; Transcription, Genetic

2002
Analysis of gene profiles involved in the enhancement of all-trans retinoic acid-induced HL-60 cell differentiation by sesquiterpene lactones identifies asparagine synthetase as a novel target for differentiation-inducing therapy.
    International journal of oncology, 2014, Volume: 44, Issue:3

    Topics: Asparagine; Aspartate-Ammonia Ligase; Cell Differentiation; Culture Media; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Oligonucleotide Array Sequence Analysis; Receptors, Retinoic Acid; Sesquiterpenes; Sesquiterpenes, Guaiane; Tretinoin

2014