parthenolide has been researched along with fluorouracil in 6 studies
*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]
*Fluorouracil: A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Du, G; Jia, X; Li, Y; Liu, Q; Wang, S; Zeng, B; Zhang, C | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Kang, SB; Kim, DG; Kim, IH; Kim, SH; Kim, SL; Kim, SW; Lee, SO; Lee, ST; Trang, KT | 1 |
| Li, Y; Liu, D; Liu, M; Liu, Y; Ran, L | 1 |
| Chen, T; Chen, Y; Ding, Y; Ge, W; Li, S; Liu, Z; Wang, M; Zhang, Q; Zhang, X | 1 |
6 other study(ies) available for parthenolide and fluorouracil
| Article | Year |
|---|---|
Synthesis, cytotoxicity, and in vivo antitumor activity study of parthenolide semicarbazones and thiosemicarbazones.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carbamates; Cell Line, Tumor; Cell Survival; Drug Screening Assays, Antitumor; Humans; Male; Mice; Mice, Inbred C57BL; Molecular Docking Simulation; Neoplasms, Experimental; NF-kappa B; Semicarbazones; Sesquiterpenes; Structure-Activity Relationship; Thiosemicarbazones | 2020 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Synergistic antitumor effect of 5-fluorouracil in combination with parthenolide in human colorectal cancer.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Apoptosis; Caspase 3; Caspase 9; Cell Cycle; Cell Line, Tumor; Colorectal Neoplasms; Cytochromes c; Drug Combinations; Drug Resistance, Neoplasm; Drug Synergism; Fluorouracil; Humans; Mice; Mice, Nude; Mitochondria; Neoplasm Transplantation; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Sesquiterpenes; Xenograft Model Antitumor Assays | 2013 |
Reversing resistance of multidrug-resistant hepatic carcinoma cells with parthenolide.
Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fluorouracil; Humans; Liver Neoplasms; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Sesquiterpenes; Tumor Suppressor Protein p53; Wnt1 Protein | 2013 |
Design and synthesis of parthenolide and 5-fluorouracil conjugates as potential anticancer agents against drug resistant hepatocellular carcinoma.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Nucleus; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Liver Neoplasms; Molecular Structure; Sesquiterpenes; Structure-Activity Relationship; Tumor Cells, Cultured | 2019 |