parthenolide has been researched along with costunolide in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.09) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 7 (31.82) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Backlund, A; Bohlin, L; Gottfries, J; Larsson, J | 1 |
| Gasteiger, J; Hofmann, A; Merfort, I; Siedle, B; Terfloth, L; Wagner, S | 1 |
| Bachelier, A; Klein, CD; Mayer, R | 1 |
| Emerenciano, VP; Fernandes, MB; Ferreira, MJ; Scotti, MT | 1 |
| Chen, Y; Ding, Y; Fan, H; Gao, Y; Han, B; Ji, Q; Jia, Y; Li, D; Li, LY; Li, Q; Lin, J; Long, J; Lu, Y; Ma, W; Ma, X; Qiu, C; Shi, Q; Shi, Y; Tong, Z; Yang, M; Zhai, J; Zhang, H; Zhang, J; Zhang, Q; Zhang, W | 1 |
| Da Costa, FB; Klempnauer, KH; Schmidt, TJ; Schomburg, C; Schuehly, W | 1 |
| Chen, Y; Ge, WZ; Gong, JM; Kuang, BJ; Li, QY; Lu, Y; Wu, H; Xi, X; Yang, ZJ; Zhang, Q | 1 |
| Chan, YM; el-Feraly, FS | 1 |
| Cole, JR; Hoffmann, JJ; Torrance, SJ; Widehopf, RM | 1 |
| Che, CT; Farnsworth, NR; Fong, HH; Mondranondra, IO; Rimando, AM; Vajrodaya, S | 1 |
| Cantrell, CL; Castañeda-Acosta, J; Fischer, NH; Franzblau, SG; Lu, T; Quijano, L | 1 |
| Castellano, D; Galindo, JC; Macías, FA; Velasco, RF | 1 |
| Hong, YS; Kim, HS; Kim, KW; Koo, TH; Lee, JH; Lee, JJ; Park, YJ | 1 |
| Cai, Y; Liu, XY; Lu, Y; Song, XK; Tu, PF; Wu, LJ; Zheng, QT; Zhu, H | 1 |
| Afshari, LK; Azam, M; Bidja, AH; Feeney, RB; Pagán, OR; Rowlands, AL; Roy, DM; Urban, KR | 1 |
| Boggs, AE; Charpentier, MS; Martin, SS; Thompson, K; Vitolo, MI; Whipple, RA | 1 |
| Chen, Y; Ding, YH; Long, J; Wang, PP; Zhang, Q | 1 |
| Mehrotra, E; Saraf, SK; Sonar, PK; Tripathi, AC; Vishwakarma, J | 1 |
| Beyraghdar Kashkooli, A; Bouwmeester, H; de Vos, RCH; Franssen, MCR; Guallar, V; Kolkman, P; Liu, Q; Lucas, MF; Manzano, D; Pateraki, I; Richard, L; van der Krol, A | 1 |
| Anuchapreeda, S; Berkland, C; Chiampanichayakul, S; Katekunlaphan, T; Khounvong, J; Rungrojsakul, M; Saosathan, S; Tima, S | 1 |
| Bouwmeester, H; Kashkooli, AB; van der Krol, A; van Dijk, ADJ | 1 |
| Ávila-Gálvez, MÁ; Bosch, D; Brito, MA; Cankar, K; Dos Santos, CN; Figueira, I; Marques, D | 1 |
22 other study(ies) available for parthenolide and costunolide
| Article | Year |
|---|---|
Expanding the ChemGPS chemical space with natural products.
Topics: Biological Products; Combinatorial Chemistry Techniques; Computer Graphics; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Molecular Structure; Prostaglandin-Endoperoxide Synthases; Structure-Activity Relationship | 2005 |
Development of a structural model for NF-kappaB inhibition of sesquiterpene lactones using self-organizing neural networks.
Topics: Lactones; Models, Molecular; Neural Networks, Computer; NF-kappa B; Quantitative Structure-Activity Relationship; Sesquiterpenes | 2006 |
Sesquiterpene lactones are potent and irreversible inhibitors of the antibacterial target enzyme MurA.
Topics: Alkyl and Aryl Transferases; Enzyme Inhibitors; Escherichia coli; Lactones; Peptidoglycan; Pseudomonas aeruginosa; Sesquiterpenes; Structure-Activity Relationship | 2006 |
Use of self-organizing maps and molecular descriptors to predict the cytotoxic activity of sesquiterpene lactones.
Topics: Antineoplastic Agents; Drug Evaluation, Preclinical; Humans; Lactones; Neural Networks, Computer; Sesquiterpenes | 2008 |
Guaianolide sesquiterpene lactones, a source to discover agents that selectively inhibit acute myelogenous leukemia stem and progenitor cells.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Hematopoietic Stem Cells; Humans; Lactones; Leukemia, Myeloid, Acute; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasm Transplantation; Neoplastic Stem Cells; Prodrugs; Sesquiterpenes; Sesquiterpenes, Guaiane; Structure-Activity Relationship; Transplantation, Heterologous | 2012 |
Natural sesquiterpene lactones as inhibitors of Myb-dependent gene expression: structure-activity relationships.
Topics: Acetyltransferases; Animals; Cell Line; Cell Survival; Chickens; Computer Simulation; Dose-Response Relationship, Drug; Gene Expression; Green Fluorescent Proteins; Inhibitory Concentration 50; Lactones; Models, Molecular; Molecular Conformation; Molecular Structure; Promoter Regions, Genetic; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myb; Sesquiterpenes; Structure-Activity Relationship | 2013 |
Syntheses and Biological Evaluation of Costunolide, Parthenolide, and Their Fluorinated Analogues.
Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Fluorine; Half-Life; Halogenation; Humans; Microsomes, Liver; Rats; Sesquiterpenes; Stereoisomerism; Structure-Activity Relationship | 2015 |
Isolation and characterization of the sesquiterpene lactones costunolide, parthenolide, costunolide diepoxide, santamarine, and reynosin from Magnolia grandiflora L.
Topics: Cyclization; Epoxy Compounds; Lactones; Oxidation-Reduction; Plant Extracts; Sesquiterpenes | 1978 |
Cytotoxic agents from Michelia champaca and Talauma ovata: parthenolide and costunolide.
Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Squamous Cell; Cell Survival; Cells, Cultured; Humans; Neoplasms, Experimental; Phytotherapy; Plants, Medicinal; Sesquiterpenes | 1977 |
Sesquiterpene lactones and other constituents from a cytotoxic extract of Michelia floribunda.
Topics: Animals; Antineoplastic Agents, Phytogenic; Aporphines; Glucosides; Lactones; Phenylpropionates; Plant Extracts; Sesquiterpenes; Tumor Cells, Cultured | 1990 |
Antimycobacterial evaluation of germacranolides.
Topics: Anti-Bacterial Agents; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium tuberculosis; Sesquiterpenes | 1998 |
Sesquiterpene lactones with potential use as natural herbicide models (I): trans,trans-germacranolides.
Topics: Herbicides; Humans; Lactones; Plants, Edible; Sesquiterpenes | 1999 |
A sesquiterpene lactone, costunolide, from Magnolia grandiflora inhibits NF-kappa B by targeting I kappa B phosphorylation.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Gene Expression Regulation; I-kappa B Proteins; Lipopolysaccharides; Macrophages; Mice; Molecular Structure; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphorylation; Plant Leaves; Plants, Medicinal; Sesquiterpenes | 2001 |
A new sesquiterpene lactone from Tsoongiodendron odorum Chun.
Topics: Antineoplastic Agents, Phytogenic; Chromatography, Gel; Crystallography, X-Ray; Formazans; Gas Chromatography-Mass Spectrometry; HeLa Cells; HL-60 Cells; Humans; KB Cells; Lactones; Magnetic Resonance Spectroscopy; Magnoliaceae; Models, Molecular; Plant Roots; Sesquiterpenes; Sesquiterpenes, Eudesmane; Terpenes; Tetrazolium Salts | 2001 |
Reversal of cocaine-induced planarian behavior by parthenolide and related sesquiterpene lactones.
Topics: Algorithms; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Hyperkinesis; Mass Spectrometry; Motor Activity; Planarians; Santonin; Sesquiterpenes; Sesquiterpenes, Eudesmane; Spectrometry, Mass, Electrospray Ionization | 2008 |
Parthenolide and costunolide reduce microtentacles and tumor cell attachment by selectively targeting detyrosinated tubulin independent from NF-κB inhibition.
Topics: Breast Neoplasms; Cell Line, Tumor; Enzyme Activation; Female; Humans; Microtubules; NF-kappa B; Protein Processing, Post-Translational; Sesquiterpenes; Signal Transduction; Tubulin | 2013 |
Protection-group-free semisyntheses of parthenolide and its cyclopropyl analogue.
Topics: Apoptosis; Cell Line, Tumor; Cyclopropanes; Humans; Sesquiterpenes | 2013 |
Schizonticidal antimalarial sesquiterpene lactones from Magnolia champaca (L.) Baill. ex Pierre: microwave-assisted extraction, HPTLC fingerprinting and computational studies.
Topics: Antimalarials; Antiprotozoal Agents; Chromatography, High Pressure Liquid; Lactones; Magnolia; Microwaves; Molecular Docking Simulation; Plant Extracts; Sesquiterpenes; Spectrum Analysis | 2019 |
Kauniolide synthase is a P450 with unusual hydroxylation and cyclization-elimination activity.
Topics: Biosynthetic Pathways; Cyclization; Cytochrome P-450 Enzyme System; Hydroxylation; Molecular Docking Simulation; Nicotiana; Saccharomyces cerevisiae; Sesquiterpenes; Tanacetum | 2018 |
Costunolide and parthenolide from Champi Sirindhorn (
Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Humans; Inhibitory Concentration 50; K562 Cells; Magnolia; Plant Extracts; Sesquiterpenes; Thailand | 2021 |
Individual lipid transfer proteins from Tanacetum parthenium show different specificity for extracellular accumulation of sesquiterpenes.
Topics: Lipids; Sesquiterpenes; Tanacetum parthenium | 2023 |
Costunolide and parthenolide: Novel blood-brain barrier permeable sesquiterpene lactones to improve barrier tightness.
Topics: Blood-Brain Barrier; Endothelial Cells; Lactones; Sesquiterpenes | 2023 |