Page last updated: 2024-08-23

paroxetine and tryptophan

paroxetine has been researched along with tryptophan in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's6 (25.00)18.2507
2000's10 (41.67)29.6817
2010's7 (29.17)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellman, K; Knegtel, RM; Settimo, L1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Badawy, AA; Morgan, CJ1
Bech, P; Bjerrum, H; Butler, B; Bøjholm, S; Folker, H; Gram, LF; Larsen, JK; Lauritzen, L; Loldrup, D; Møller, SE1
Magnussen, I1
Bristow, LJ; Cunningham, JR; Hogg, JE; Hutson, PH; Longmore, J; Murray, F; Pearce, D; Razzaque, Z; Saywell, K; Tricklebank, MD1
Carpenter, LL; Epperson, CN; McDougle, CJ; Price, LH1
Arango, V; Henteleff, RA; Lagattuta, TF; Li, S; Mann, JJ; Perper, JA1
McAllister-Williams, RH; Porter, RJ; Young, AH1
Croonenberghs, J; Deboutte, D; Delmeire, L; Lin, AH; Maes, M; Meskal, A; Neels, H; Pison, G; Scharpe, S; Van der Planken, M; Verkerk, R1
Delmeire, L; Maes, M; Scharpé, S; Van Gastel, A; van Hunsel, F; Verkerk, R1
Blier, P; Diksic, M; Okazawa, H; Yamane, F1
Adrover, M; Argyropoulos, S; Bell, C; Forshall, S; Hood, S; Nash, J; Nutt, DJ; Rich, A1
Capuron, L; Fuchs, D; Lawson, DH; Miller, AH; Musselman, DL; Nemeroff, CB; Neurauter, G1
Callebert, J; Chabane, N; Delorme, R; Falissard, B; Launay, JM; Leboyer, M; Mouren-Siméoni, MC; Rouillon, F1
Bergan, A; Chopra, MP; Crits-Christoph, P; DeRubeis, RJ; Gallop, R; O'Reardon, JP1
Cedeño, N; Lima, L; Obregón, F; Urbina, M1
Hasegawa, H; Hirose, S; Lin, QS; Nakamura, K; Nishimura, H; Ohashi, A; Ohtsuji, M; Sawabe, K; Sugawara, Y; Tsurui, H; Xiu, Y1
Caccia, S; Calcagno, E; Canetta, A; Cervo, L; Fracasso, C; Guzzetti, S; Invernizzi, RW; Sacchetti, G1
Castro, WL; Delgado, PL; El Khoury, A; Mathé, AA; Misiaszek, J; Moreno, FA; Palmer, C; Parkinson, D; Wright, R1
Blokland, A; Dawson, N; Ferrington, L; Kelly, PA; Prickaerts, J; Steinbusch, HW; van Donkelaar, EL1
Bermudez, I; Franklin, M; Gaburro, S; Murck, H; Singewald, N1
Argyropoulos, SV; Bell, CJ; Hood, SD; Nutt, DJ1
Bermudez, I; Csanova, A; Franklin, M; Hlavacova, N; Jezova, D; Li, Y; Sanchez, C1

Reviews

2 review(s) available for paroxetine and tryptophan

ArticleYear
A risk-benefit assessment of drugs used in the management of obsessive-compulsive disorder.
    Drug safety, 1996, Volume: 15, Issue:2

    Topics: 1-Naphthylamine; Adult; Aged; Antidepressive Agents; Buspirone; Child; Clomipramine; Clonazepam; Costs and Cost Analysis; Dopamine Antagonists; Drug Interactions; Drug Tolerance; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Lithium; Obsessive-Compulsive Disorder; Paroxetine; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Sertraline; Tryptophan

1996
Don't panic. A guide to tryptophan depletion with disorder-specific anxiety provocation.
    Journal of psychopharmacology (Oxford, England), 2016, Volume: 30, Issue:11

    Topics: Anxiety; Anxiety Disorders; Humans; Male; Paroxetine; Serotonin; Tryptophan

2016

Trials

7 trial(s) available for paroxetine and tryptophan

ArticleYear
Plasma ratio tryptophan/neutral amino acids in relation to clinical response to paroxetine and clomipramine in patients with major depression.
    Journal of affective disorders, 1990, Volume: 18, Issue:1

    Topics: Adult; Aged; Amino Acids; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Middle Aged; Paroxetine; Piperidines; Serotonin Antagonists; Tryptophan

1990
Acute effects of venlafaxine and paroxetine on serotonergic transmission in human volunteers.
    Psychopharmacology, 1999, Volume: 146, Issue:2

    Topics: Adolescent; Adult; Area Under Curve; Clomipramine; Cyclohexanols; Human Growth Hormone; Humans; Male; Nausea; Paroxetine; Prolactin; Selective Serotonin Reuptake Inhibitors; Serotonin; Synaptic Transmission; Tryptophan; Venlafaxine Hydrochloride; Vomiting

1999
Does 5-HT restrain panic? A tryptophan depletion study in panic disorder patients recovered on paroxetine.
    Journal of psychopharmacology (Oxford, England), 2002, Volume: 16, Issue:1

    Topics: Adult; Affect; Aged; Agoraphobia; Cross-Over Studies; Double-Blind Method; Female; Flumazenil; GABA Modulators; Hemodynamics; Humans; Male; Middle Aged; Panic Disorder; Paroxetine; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan

2002
Interferon-alpha-induced changes in tryptophan metabolism. relationship to depression and paroxetine treatment.
    Biological psychiatry, 2003, Nov-01, Volume: 54, Issue:9

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Anxiety; Depression; Double-Blind Method; Female; Humans; Interferon-alpha; Kynurenine; Male; Melanoma; Middle Aged; Neopterin; Paroxetine; Selective Serotonin Reuptake Inhibitors; Time Factors; Tryptophan

2003
Platelet serotonergic predictors of clinical improvement in obsessive compulsive disorder.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Binding Sites; Biomarkers; Blood Platelets; Carrier Proteins; Cell Membrane; Child; Diet; Female; France; Humans; Imipramine; Inositol Phosphates; Iodine Isotopes; Lysergic Acid Diethylamide; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Obsessive-Compulsive Disorder; Paroxetine; Psychiatric Status Rating Scales; Radiochemistry; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Treatment Outcome; Tritium; Tryptophan

2004
Response to tryptophan depletion in major depression treated with either cognitive therapy or selective serotonin reuptake inhibitor antidepressants.
    Biological psychiatry, 2004, May-01, Volume: 55, Issue:9

    Topics: Cognitive Behavioral Therapy; Cross-Over Studies; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Drug Administration Schedule; Female; Fluoxetine; Humans; Male; Middle Aged; Paroxetine; Remission Induction; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Tryptophan

2004
CSF neurochemicals during tryptophan depletion in individuals with remitted depression and healthy controls.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:1

    Topics: Adult; Analysis of Variance; Case-Control Studies; Chromatography, High Pressure Liquid; Circadian Rhythm; Cross-Over Studies; Depressive Disorder, Major; Double-Blind Method; Electrochemistry; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Indoles; Male; Methoxyhydroxyphenylglycol; Middle Aged; Neurochemistry; Neuropeptide Y; Paroxetine; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Tryptophan; Young Adult

2010

Other Studies

15 other study(ies) available for paroxetine and tryptophan

ArticleYear
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Effects of acute paroxetine administration on tryptophan metabolism and disposition in the rat.
    British journal of pharmacology, 1991, Volume: 102, Issue:2

    Topics: Administration, Oral; Animals; Antidepressive Agents; Brain; Corticosterone; Enzyme Induction; Hydrocortisone; In Vitro Techniques; Liver; Male; Paroxetine; Piperidines; Rats; Rats, Inbred Strains; Tryptophan; Tryptophan Oxygenase

1991
p,p'-DDT-induced myoclonus in mice: the effect of enhanced 5-HT neurotransmission.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; DDT; Female; Mice; Mice, Inbred Strains; Myoclonus; Paroxetine; Piperidines; Serotonin; Synaptic Transmission; Tryptophan

1985
The effects of GR127935, a putative 5-HT1D receptor antagonist, on brain 5-HT metabolism, extracellular 5-HT concentration and behaviour in the guinea pig.
    Neuropharmacology, 1995, Volume: 34, Issue:4

    Topics: Animals; Biogenic Monoamines; Brain; Dyskinesia, Drug-Induced; Electric Stimulation; Fluoxetine; Guinea Pigs; Humans; In Vitro Techniques; Male; Methiothepin; Oxadiazoles; Paroxetine; Piperazines; Raphe Nuclei; Serotonin Antagonists; Synaptic Transmission; Tryptophan

1995
Lower 3H-paroxetine binding in cerebral cortex of suicide victims is partly due to fewer high affinity, non-transporter sites.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:11

    Topics: 5-Hydroxytryptophan; Adult; Antidepressive Agents, Second-Generation; Carrier Proteins; Cerebral Cortex; Female; Humans; Hydroxyindoleacetic Acid; Kinetics; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Paroxetine; Receptors, Presynaptic; Receptors, Serotonin; Serotonin Plasma Membrane Transport Proteins; Suicide; Tryptophan

1996
Peripheral markers of serotonergic and noradrenergic function in post-pubertal, caucasian males with autistic disorder.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2000, Volume: 22, Issue:3

    Topics: Adolescent; Autistic Disorder; Belgium; Biomarkers; Child; Dopamine; Epinephrine; Humans; Hydroxyindoleacetic Acid; Intelligence; Male; Netherlands; Norepinephrine; Paroxetine; Puberty; Serotonin; Tryptophan; Tyrosine; White People; Yohimbine

2000
Serotonergic markers and lowered plasma branched-chain-amino acid concentrations in fibromyalgia.
    Psychiatry research, 2000, Dec-04, Volume: 97, Issue:1

    Topics: Adult; Amino Acids, Branched-Chain; Biomarkers; Case-Control Studies; Female; Fibromyalgia; Humans; Isoleucine; Leucine; Male; Middle Aged; Paroxetine; Phenylalanine; Selective Serotonin Reuptake Inhibitors; Tryptophan; Valine

2000
Reduction in serotonin synthesis following acute and chronic treatments with paroxetine, a selective serotonin reuptake inhibitor, in rat brain: an autoradiographic study with alpha-[14C]methyl-L-tryptophan(2).
    Biochemical pharmacology, 2001, Dec-01, Volume: 62, Issue:11

    Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Carrier Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tryptophan

2001
Characterization of serotonin transporter in blood lymphocytes of rats. Modulation by in vivo administration of mitogens.
    Journal of neuroimmunology, 2005, Volume: 159, Issue:1-2

    Topics: Animals; Binding, Competitive; Cell Membrane; Chromatography, High Pressure Liquid; Concanavalin A; Hydroxyindoleacetic Acid; Injections, Intraperitoneal; Kinetics; Lipopolysaccharides; Lymphocytes; Male; Membrane Glycoproteins; Membrane Transport Modulators; Membrane Transport Proteins; Mitogens; Nerve Tissue Proteins; Paroxetine; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Plasma Membrane Transport Proteins; Tryptophan; Up-Regulation

2005
Late developmental stage-specific role of tryptophan hydroxylase 1 in brain serotonin levels.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006, Jan-11, Volume: 26, Issue:2

    Topics: Animals; Antidepressive Agents; Biopterins; Brain; Chlorocebus aethiops; COS Cells; Depression; Enzyme Induction; Freezing Reaction, Cataleptic; Gene Expression Regulation, Developmental; Humans; Imipramine; Mice; Mice, Inbred Strains; Paroxetine; Raphe Nuclei; Recombinant Fusion Proteins; RNA, Messenger; Serotonin; Tryptophan; Tryptophan Hydroxylase

2006
Strain differences in paroxetine-induced reduction of immobility time in the forced swimming test in mice: role of serotonin.
    European journal of pharmacology, 2008, Oct-10, Volume: 594, Issue:1-3

    Topics: Animals; Antidepressive Agents, Second-Generation; Brain Chemistry; Depression; Male; Melatonin; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Motor Activity; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin; Species Specificity; Swimming; Tryptophan

2008
Acute tryptophan depletion potentiates 3,4-methylenedioxymethamphetamine-induced cerebrovascular hyperperfusion in adult male Wistar rats.
    Journal of neuroscience research, 2010, May-15, Volume: 88, Issue:7

    Topics: Animals; Binding, Competitive; Brain; Cerebral Arteries; Cerebrovascular Circulation; Cerebrovascular Disorders; Depressive Disorder; Disease Models, Animal; Hyperemia; Male; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Rats; Rats, Wistar; Serotonin; Serotonin Agents; Serotonin Plasma Membrane Transport Proteins; Tryptophan; Vasodilation

2010
Sub-chronic dietary tryptophan depletion--an animal model of depression with improved face and good construct validity.
    Journal of psychiatric research, 2012, Volume: 46, Issue:2

    Topics: Aldosterone; Analysis of Variance; Animals; Body Weight; Brain; Calcium-Binding Proteins; Catecholamines; Chromatography, High Pressure Liquid; Corticosterone; Depression; Diet; Disease Models, Animal; DNA-Binding Proteins; Kynurenic Acid; Kynurenine; Male; Nerve Tissue Proteins; Nucleobindins; Paroxetine; Protein Binding; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Selective Serotonin Reuptake Inhibitors; Swimming; Time Factors; Tritium; Tryptophan

2012
Contrasting effects of vortioxetine and paroxetine on pineal gland biochemistry in a tryptophan-depletion model of depression in female rats.
    Progress in neuro-psychopharmacology & biological psychiatry, 2017, 10-03, Volume: 79, Issue:Pt B

    Topics: Administration, Oral; Animals; Antidepressive Agents, Second-Generation; Depressive Disorder; Disease Models, Animal; Female; Glutamic Acid; Melatonin; Norepinephrine; Paroxetine; Pineal Gland; Piperazines; Random Allocation; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA-Binding Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Sulfides; Tryptophan; Vortioxetine

2017