paroxetine has been researched along with tramadol in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 3 (18.75) | 2.80 |
| Authors | Studies |
|---|---|
| De Laat, M; Devulder, J; Dumoulin, K; Renson, A; Rolly, G | 1 |
| Brodie-Meijer, CC; Egberts, AC; ter Borgh, J | 1 |
| Buchalter, EN; Giambanco, V; Lantz, MS | 1 |
| Brøsen, K; Enggaard, TP; Laugesen, S; Pedersen, RS; Sindrup, SH | 1 |
| Escrivá-Moscardó, S; Llinares-Tello, F; Martínez-Mascaraque, P; Martínez-Pastor, F | 1 |
| John, AP; Koloth, R | 1 |
| Olivier, B; Schweitzer, DH; Waldinger, MD; Zwinderman, AH | 1 |
| Drummer, OH; Gerostamoulos, D; Pilgrim, JL | 1 |
| Brosen, K; Damkier, P; Nielsen, AG; Noehr-Jensen, L; Pedersen, RS | 1 |
| Alghobary, M; Amr, M; El-Bayoumy, Y; Mahmoud, el-HM; Mostafa, Y | 1 |
| Dimpfel, W | 1 |
| Esquivel Franco, DC; Olivier, B; Olivier, JD; Oosting, R; Sarnyai, Z; Waldinger, M | 1 |
| Daali, Y; Desmeules, J; Lenglet, S; Matthey, A; Storelli, F; Thomas, A | 1 |
| Cui, Y; Feng, F; Tan, H; Zhang, Y; Zhou, Z | 1 |
| Cui, Y; Wang, Y; Yang, Z; Zhang, X; Zhang, Y; Zhou, Z | 1 |
| Doss C, GP; Kumar S, U; Tayubi, IA | 1 |
2 review(s) available for paroxetine and tramadol
| Article | Year |
|---|---|
A systematic review and meta-analysis of randomized controlled trials of "on-demand" use of tramadol vs "on-demand" use of paroxetine in the management of patients with premature ejaculation.
Topics: Ejaculation; Humans; Male; Paroxetine; Premature Ejaculation; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Tramadol; Treatment Outcome | 2021 |
The network meta-analysis of "on-demand" and "daily" use of paroxetine in treating men with premature ejaculation from randomized controlled trials.
Topics: Ejaculation; Humans; Male; Network Meta-Analysis; Paroxetine; Phosphodiesterase 5 Inhibitors; Premature Ejaculation; Randomized Controlled Trials as Topic; Selective Serotonin Reuptake Inhibitors; Tramadol; Treatment Outcome | 2022 |
3 trial(s) available for paroxetine and tramadol
| Article | Year |
|---|---|
Paroxetine, a cytochrome P450 2D6 inhibitor, diminishes the stereoselective O-demethylation and reduces the hypoalgesic effect of tramadol.
Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Area Under Curve; Cross-Over Studies; Cytochrome P-450 CYP2D6; Double-Blind Method; Drug Interactions; Female; Humans; Male; Molecular Conformation; Pain Threshold; Paroxetine; Tramadol; Treatment Outcome | 2005 |
Two separate dose-dependent effects of paroxetine: mydriasis and inhibition of tramadol's O-demethylation via CYP2D6.
Topics: Adult; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Cytochrome P-450 CYP2D6 Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Paroxetine; Pupil; Tramadol | 2010 |
Evaluation of tramadol on demand vs. daily paroxetine as a long-term treatment of lifelong premature ejaculation.
Topics: Adult; Analgesics, Opioid; Drug Administration Schedule; Egypt; Ejaculation; Follow-Up Studies; Humans; Libido; Long-Term Care; Male; Paroxetine; Penile Erection; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunction, Physiological; Tramadol | 2010 |
11 other study(ies) available for paroxetine and tramadol
| Article | Year |
|---|---|
Nightmares and hallucinations after long-term intake of tramadol combined with antidepressants.
Topics: Aged; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Dothiepin; Dreams; Hallucinations; Humans; Male; Paroxetine; Tramadol | 1996 |
Serotonin syndrome attributed to tramadol addition to paroxetine therapy.
Topics: Analgesics, Opioid; Drug Interactions; Humans; Male; Middle Aged; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin; Tramadol | 1997 |
Serotonin syndrome following the administration of tramadol with paroxetine.
Topics: Aged; Aged, 80 and over; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Autonomic Nervous System Diseases; Central Nervous System Diseases; Depression; Drug Interactions; Female; Humans; Pain; Paroxetine; Selective Serotonin Reuptake Inhibitors; Syndrome; Tramadol | 1998 |
[Possible serotoninergic syndrome associated with coadministration of paroxetine and tramadol].
Topics: Aged; Aged, 80 and over; Algorithms; Analgesics, Opioid; Antidepressive Agents, Second-Generation; Depressive Disorder; Drug Interactions; Drug Therapy, Combination; Female; Humans; Iatrogenic Disease; Osteoarthritis; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Time Factors; Tramadol | 2007 |
Severe serotonin toxicity and manic switch induced by combined use of tramadol and paroxetine.
Topics: Analgesics, Opioid; Bipolar Disorder; Depressive Disorder, Major; Drug Therapy, Combination; Female; Humans; Middle Aged; Pain; Paroxetine; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome; Tramadol | 2007 |
The majority of men with lifelong premature ejaculation prefer daily drug treatment: an observation study in a consecutive group of Dutch men.
Topics: Adult; Benzylamines; Clomipramine; Cohort Studies; Coitus; Dose-Response Relationship, Drug; Ejaculation; Humans; Male; Middle Aged; Naphthalenes; Netherlands; Paroxetine; Patient Satisfaction; Selective Serotonin Reuptake Inhibitors; Sexual Dysfunction, Physiological; Tramadol; Treatment Outcome | 2007 |
Deaths involving serotonergic drugs.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Australia; Cause of Death; Citalopram; Cyclohexanols; Female; Fluoxetine; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Serotonin Agents; Sertraline; Tramadol; Venlafaxine Hydrochloride | 2010 |
Pharmacological classification of herbal extracts by means of comparison to spectral EEG signatures induced by synthetic drugs in the freely moving rat.
Topics: Animals; Brain; Caffeine; Electroencephalography; Magnoliopsida; Methylphenidate; Paroxetine; Phenytoin; Plant Extracts; Rats; Tramadol | 2013 |
Tramadol: Effects on sexual behavior in male rats are mainly caused by its 5-HT reuptake blocking effects.
Topics: Animals; Dose-Response Relationship, Drug; Drug Interactions; Ejaculation; Male; Naloxone; Narcotic Antagonists; Paroxetine; Piperazines; Pyridines; Random Allocation; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Receptors, Opioid, mu; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Sexual Behavior, Animal; Tramadol | 2017 |
Impact of CYP2D6 Functional Allelic Variations on Phenoconversion and Drug-Drug Interactions.
Topics: Adolescent; Adult; Alleles; Analgesics, Opioid; Antitussive Agents; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP2D6 Inhibitors; Dextromethorphan; Drug Interactions; Duloxetine Hydrochloride; Female; Genotype; Heterozygote; Homozygote; Humans; Male; Paroxetine; Pharmacogenomic Variants; Phenotype; Tramadol; Young Adult | 2018 |
Identification of potential inhibitors, conformational dynamics, and mechanistic insights into mutant Kirsten rat sarcoma virus (G13D) driven cancers.
Topics: Humans; Kirsten murine sarcoma virus; Molecular Docking Simulation; Molecular Dynamics Simulation; Neoplasms; Paroxetine; Prospective Studies; Proto-Oncogene Proteins p21(ras); Tramadol | 2022 |