Page last updated: 2024-08-23

paroxetine and substance p

paroxetine has been researched along with substance p in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's5 (50.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hill, DR; Stoessl, AJ1
Carlson, EJ; Carman, J; Cascieri, MA; Chicchi, GG; Cutler, N; Feighner, J; Hale, JJ; Hargreaves, RJ; Harrison, T; Hefti, F; Hewson, L; Hill, RG; Kramer, MS; Liu, G; MacCoss, M; Mills, SG; Reines, SA; Rupniak, NM; Sadowski, S; Scolnick, EM; Shrivastava, R; Smith, D; Snavely, D; Sramek, JJ; Swain, CJ; Williams, AR; Wyatt-Knowles, E1
Nutt, D1
Alberti, I; Boni, C; De Felipe, C; Froger, N; Gardier, AM; Hamon, M; Hunt, SP; Jacquot, C; Lanfumey, L; Lena, I; Moratalla, R; Rupniak, NM1
Salzman, C1
Krishnan, R; Ranga, K1
Baghai, TC; Bondy, B; Minov, C; Möller, HJ; Rupprecht, R; Schüle, C; Schwarz, MJ; Zwanzger, P1
Berger, M; Fiebich, BL; Grunze, H; Lieb, K; Normann, C; Walden, J1
Gehlert, DR; Iyengar, S; Kielbasa, W; Marek, G; Mozley, D; Peng, X; Tauscher, J; Vandenhende, F1
Alesci, S; Bonne, O; Charney, DS; Collins, C; Gill, JM; Kinkead, B; Luckenbaugh, DA; Manji, HK; Neumeister, A; Owens, MJ; Vythilingam, M; Yuan, P1

Reviews

1 review(s) available for paroxetine and substance p

ArticleYear
Substance P in depression.
    The Harvard mental health letter, 2001, Volume: 18, Issue:6

    Topics: Animals; Antidepressive Agents, Second-Generation; Humans; Paroxetine; Research Design; Selective Serotonin Reuptake Inhibitors; Serotonin; Substance P

2001

Trials

6 trial(s) available for paroxetine and substance p

ArticleYear
Distinct mechanism for antidepressant activity by blockade of central substance P receptors.
    Science (New York, N.Y.), 1998, Sep-11, Volume: 281, Issue:5383

    Topics: Adolescent; Adult; Aged; Amygdala; Animals; Antidepressive Agents, Second-Generation; Aprepitant; Behavior, Animal; Brain; Depressive Disorder; Female; Gerbillinae; Guinea Pigs; Humans; Male; Middle Aged; Morpholines; Neurokinin-1 Receptor Antagonists; Norepinephrine; Paroxetine; Receptors, Neurokinin-1; Serotonin; Stress, Psychological; Substance P; Vocalization, Animal

1998
Substance-P antagonists: a new treatment for depression?
    Lancet (London, England), 1998, Nov-21, Volume: 352, Issue:9141

    Topics: Antidepressive Agents, Second-Generation; Anxiety Disorders; Aprepitant; Depressive Disorder; Double-Blind Method; Humans; Morpholines; Paroxetine; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Substance P

1998
Clinical experience with substance P receptor (NK1) antagonists in depression.
    The Journal of clinical psychiatry, 2002, Volume: 63 Suppl 11

    Topics: Antidepressive Agents; Anxiety Disorders; Aprepitant; Depressive Disorder; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Ethers; Female; Humans; Hydrocarbons, Fluorinated; Male; Morpholines; Neurokinin-1 Receptor Antagonists; Paroxetine; Placebos; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Substance P; Treatment Outcome

2002
Substance P serum levels are increased in major depression: preliminary results.
    Biological psychiatry, 2003, Mar-15, Volume: 53, Issue:6

    Topics: Adult; Aged; Antidepressive Agents, Tricyclic; Depressive Disorder, Major; Diagnostic and Statistical Manual of Mental Disorders; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Mianserin; Middle Aged; Mirtazapine; Paroxetine; Selective Serotonin Reuptake Inhibitors; Severity of Illness Index; Substance P; Time Factors

2003
Serum levels of substance P and response to antidepressant pharmacotherapy.
    Pharmacopsychiatry, 2004, Volume: 37, Issue:5

    Topics: Acute Disease; Adult; Antidepressive Agents; Depressive Disorder, Major; Humans; Lamotrigine; Paroxetine; Severity of Illness Index; Substance P; Surveys and Questionnaires; Triazines

2004
Development of the 2nd generation neurokinin-1 receptor antagonist LY686017 for social anxiety disorder.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010, Volume: 20, Issue:2

    Topics: Adult; Animals; Anti-Anxiety Agents; Anxiety Disorders; Brain; Dose-Response Relationship, Drug; Gerbillinae; Humans; Male; Neurokinin-1 Receptor Antagonists; Paroxetine; Peptide Fragments; Pyridines; Radioligand Assay; Radionuclide Imaging; Receptors, Neurokinin-1; Stereotyped Behavior; Substance P; Treatment Outcome; Triazoles

2010

Other Studies

3 other study(ies) available for paroxetine and substance p

ArticleYear
Autoradiographic visualization of NK-3 tachykinin binding sites in the rat brain, utilizing [3H]senktide.
    Brain research, 1990, Nov-26, Volume: 534, Issue:1-2

    Topics: 5,7-Dihydroxytryptamine; Animals; Autoradiography; Brain; Kinetics; Male; Organ Specificity; Paroxetine; Peptide Fragments; Piperidines; Rats; Rats, Inbred Strains; Receptors, Neurotransmitter; Receptors, Tachykinin; Reference Values; Serotonin Antagonists; Substance P; Tachykinins; Tritium

1990
5-hydroxytryptamine (5-HT)1A autoreceptor adaptive changes in substance P (neurokinin 1) receptor knock-out mice mimic antidepressant-induced desensitization.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, Oct-15, Volume: 21, Issue:20

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Autoreceptors; Drug Resistance; Electrophysiology; Immunohistochemistry; In Vitro Techniques; Male; Mice; Mice, Knockout; Neurons; Paroxetine; Piperazines; Pyridines; Pyrimidines; Raphe Nuclei; Receptors, Neurokinin-1; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; RNA, Messenger; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Serotonin Receptor Agonists; Substance P

2001
Corticotropin-releasing factor, interleukin-6, brain-derived neurotrophic factor, insulin-like growth factor-1, and substance P in the cerebrospinal fluid of civilians with posttraumatic stress disorder before and after treatment with paroxetine.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:8

    Topics: Adult; Antidepressive Agents, Second-Generation; Brain-Derived Neurotrophic Factor; Chronic Disease; Corticotropin-Releasing Hormone; Female; Humans; Insulin-Like Growth Factor I; Interleukin-6; Male; Middle Aged; Paroxetine; Personality Inventory; Psychometrics; Stress Disorders, Post-Traumatic; Substance P; Treatment Outcome

2011